Did You Know...
...that the Band-Aid Bandage was invented by a Johnson & Johnson employee whose wife had cut herself? Earl Dickson's wife was rather accident prone, so he set out to develop a bandage that she could apply without help. He placed a small piece of gauze in the center of a small piece of surgical tape, and what we know today as the Band Aid bandage was born!
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| Number | Title | Issue Date |
| 7888133 | Method of detecting auto-antibodies from patients suffering from rheumatoid arthritis, a peptide and an assay kit The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fila... | 02/15/2011 |
| 7335724 | Peptides immunoreactive with autoantibodies from patients suffering from rheumatoid arthritis The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine res... | 02/26/2008 |
| 7267963 | Modified plant viruses and methods of use thereof The present invention relates to modulating the nature and/or level of an immune response to a molecule. In particular, the invention relates to effecting an increase in the TH1 immune response to molecules such as, but not limited to, antigens or immunogens. The in... | 09/11/2007 |
| 7205382 | Peptides, the production and use thereof for binding immunoglobulins Peptides having the following amino acid sequence as well as peptides or proteins which contain this amino acid sequence: R1-X01-X02-X03-X04-X05-X06-X07-X08-X09-X10-X11-X12-X13-R2. These peptides have a high affinity for imm... | 04/17/2007 |
| 7153887 | Use of 15-deoxyspergualin for the treatment of ANCA associated vasculitis The invention describes the use of deoxyspergualin (DSG) or an analogue thereof for the preparation of a medicament for the treatment of and/or prophylaxis against hyperreactive inflammatory diseases and autoimmune diseases, wherein the treatment is performed in cyc... | 12/26/2006 |
| 6951716 | Anti-platelet immunoglobulin bead positive control Immunoassay methods and apparatus are provided which utilize flow cytometry, coated latex microspheres, and fluorochrome labeled antibodies, to simultaneously detect the presence and amount of one or more analytes in a sample. Beads of several different sizes, color... | 10/04/2005 |
| 6933106 | Platelet immunoglobulin bead suspension and flow cytometry Immunoassay methods and apparatus are provided which utilize flow cytometry, coated latex microspheres, and fluorochrome labeled antibodies, to simultaneously detect the presence and amount of one or more analytes in a sample. By combining FALS and fluorescence, it ... | 08/23/2005 |
| 6920722 | Elongated truss boom structures for space applications An elongated truss boom structure is adapted to be flattened and coiled to a stowed configuration. The truss boom includes longerons, battens, and diagonals A fixed ladder shaped structure is formed by a plurality of fixedly coupled battens which interconnect two ad... | 07/26/2005 |
| 6890720 | Antigens derived from filaggrin and their use for diagnosing rheumatoid polyarthritis The invention concerns an artificial antigen specifically identified by the anti-filaggrin autoantibodies present in the serum of patients suffering from rheumatoid polyarthritis, and consisting of one polypeptide comprising all or part of the sequence of one filagg... | 05/10/2005 |
| 6858438 | Peptides immunoreactive with autoantibodies from patients with rheumatoid arthritis The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine res... | 02/22/2005 |
| 6638723 | Method for diagnosing autoimmune diseases A method of diagnosing an autoimmune disease is disclosed which involves determining whether autoantibodies from a body fluid react with a microtubule organizing center (MTOC). This diagnostic procedure provides a simple, highly specific, and highly relia... | 10/28/2003 |
| 6489129 | Antigen-specific IgM detection The invention concerns a method for the determination of antigen-specific antibodies of the immunoglobulin M class in the presence of immunoglobulins of the G class and/or rheumatoid factors in body fluids by incubation with at least two different recepto... | 12/03/2002 |
| 6372715 | Use of erythropoientin and iron preparations for producing pharmaceutical combination preparations for treating rheumatic diseases The present invention is concerned with the use of individual administration forms of an erythropoietin preparation and a physiologically compatible iron preparation corresponding to an equivalent amount of 1-40 mg of iron ions for the production of a pha... | 04/16/2002 |
| 6303325 | Method for detecting analytes The invention relates to methods of determining the presence or amount of an analyte in a sample suspected of containing the analyte, said method comprising the steps of: (a) bringing together in an aqueous medium to form a mixture: (i) the sample; (ii) a... | 10/16/2001 |
| 6225442 | Method of detecting autoantibody present in the serum of rheumatic A reagent for immunologically detecting rheumatism containing as an antigen at least one mammalian protein selected from among ezrin, radixin and moesin and/or a peptide composed of at least nine consecutive amino acid residues found in the amino acid seq... | 05/01/2001 |
| 6159748 | Evaluation of autoimmune diseases using a multiple parameter latex bead suspension and flow cytometry Immunoassay methods and apparatus are provided which utilize flow cytometry, coated latex microspheres, and labelled antibodies, to simultaneously detect the presence and amount of several antigens or antibodies in a sample. Microspheres can be sized by f... | 12/12/2000 |
| 6136610 | Method and apparatus for performing a lateral flow assay An embodiment of the present invention provides a method for performing a lateral flow assay. The method includes depositing a sample on a test strip at an application region, detecting a first detection signal arising from the test strip in the first det... | 10/24/2000 |
| 6100098 | Anti-AGE IgG and uses thereof for the diagnosis of severe disease The present invention relates to the diagnosis of severe diseases based on the determination of the presence of AGE-IgG autoantibodies in patients and to a method of treatment thereof. More precisely, the invention relates to a method for the diagnosis of... | 08/08/2000 |
| 5989922 | Method for determining rheumatoid factors and agents for carrying out the method The invention relates to an immunochemical method for the detection and determination of rheumatoid factors using immune complexes as specific binding partners as well as to the preparation of reagents that are suitable for these methods.... | 11/23/1999 |
| 5976810 | Method of detecting autoantibody present in the serum of rheumatic A reagent for immunologically detecting rheumatism containing as an antigen at least one mammalian protein selected from among ezrin, radixin and moesin and/or a peptide composed of at least nine consecutive amino acid residues found in the amino acid seq... | 11/02/1999 |
| 5965378 | Antibody class-specific interference eliminating reagent The invention concerns a composition composed of several different antibodies or/and antibody fragments which is suitable as a reagent to reduce interferences in an immunological method for the class-specific detection of antibodies from one or several of... | 10/12/1999 |
| 5888833 | Antigens recognized by antibodies to rheumatoid arthritis, their preparation and their applications The present invention relates to antigens extracted from mammalian malpighian epithelia, in particular rat esophageal epithelium or human epidermis, which are specifically recognized by the autoantibodies present in patients suffering form rheumatoid arth... | 03/30/1999 |
| 5846532 | Method and composition for the treatment of disorders involving immunological dysfunction A method and composition are provided for treatment of disorders involving immunological dysfunction. The invention comprises the administration of a low level of ribonucleotide polymerase protein or a derivative thereof to a human or animal with an immun... | 12/08/1998 |
| 5834215 | Method for detecting antipolymer antibodies and diagnosing silicone related disease (SRD) fibromyalgia and chronic fatigue syndrome (CFS) The present invention provides for a method of detecting antipolymer antibodies, and a method for detecting silicone related disease, fibromyalgia, and chronic fatigue syndrome.... | 11/10/1998 |
| 5831037 | Method for clinical examination based on the structures of immunoglobin G-linked oligosaccharides The present invention relates to a novel clinical examination method which comprises analyzing the alteration in the amount of a specific component in oligosaccharides of immunogloblin G. Human diseases such as liver diseases, malignant hypertension, immu... | 11/03/1998 |
| 5804391 | Elimination of rheumatoid factor interference using anti-FD antibodies The invention concerns the use of a composition which is composed of several different antibodies or/and antibody fragments which serves as a reagent to eliminate rheumatoid factor interference in an immunochemical method.... | 09/08/1998 |
| 5804188 | Method and composition for treatment of disorders involving immunological dysfunction A method and composition are provided for treatment of disorders involving immunological dysfunction. The invention comprises the administration of a low level of ribonucleotide polymerase protein or a derivative thereof to a human or animal with an immun... | 09/08/1998 |
| 5786154 | Human phospholipase activating protein and methods for diagnosis of rheumatoid arthritis The invention provides methods for detecting elevated levels of phospholipase A2 activating protein in persons suspected of having rheumatoid arthritis to thereby indicate the presence of rheumatoid arthritis in the person comprising the steps ... | 07/28/1998 |
| 5776708 | Method for identifying T cells involved in autoimmune disease The invention relates to a method for identifying T cell populations involved in autoimmune diseases. This involves determining levels of a Vଲ element in a body fluid sample of a patient and comparing this to normal levels. Variation from normal lev... | 07/07/1998 |
| 5747266 | Assay and method for determining newborn risk for sudden infant death syndrome An assay and method for screening newborns to determine risk of Sudden Infant Syndrome is described. The assay and method is based on the detection of elevated IgM-anti-IgG (MAG) levels in newborns' serum within the first year of birth. In particular, it ... | 05/05/1998 |
| 5698393 | Method for elimination of rheumatoid factor interference in diagnostic assays A method for treating biological samples, e.g., human sera or plasma, suspected of containing rheumatoid factors to eliminate cross-reactivity and false positive assay results in IgM immunoassays that are caused by the presence of rheumatoid factors in th... | 12/16/1997 |
| 5620859 | Method to aid in the diagnosis of silicone related disease A process to aid in the diagnosis of silicone related disease in which a correlation between silicone related disease and the presence of antibodies that bind to partially polymerized acrylamide is disclosed.... | 04/15/1997 |
| 5556745 | Method for the detection and quantitative determination of antigen in a test sample containing immune complexes of antigen bound to antibodies and to rheumatoid factors The invention is a simple and rapid method for immune complex dissociation and destruction of rheumatoid factors. It permits the quantitative measurement of the total, i.e., free and immune complex-bound, antigen contained in a test sample. The method inv... | 09/17/1996 |
| 5556759 | Assay and method for determining newborn risk for sudden infant death syndrome An assay and method for screening newborns to determine risk of Sudden Infant Syndrome is described. The assay and method is based on the detection of elevated IgM-anti-IgG (MAG) levels in newborns' serum within the first year of birth. In particular, it ... | 09/17/1996 |
| 5496520 | Rotary fluid manipulator A rotary fluid manipulator utilizable as a diagnostic device includes a porous body having fluid passages defined therein by fluid blocking means in the porosities of the body such as openings or slots in the body or compaction of areas of the porous body... | 03/05/1996 |
| 5486452 | Devices and kits for immunological analysis New devices and kits for solid-phase immuno-assays comprising a solid porous support, preferably in the form of a sheet, where antigens or immuno-globulins or both of them are bound by direct application in any suitable geometry, e.g. as an assay of dots ... | 01/23/1996 |
| 5472849 | Method for detecting inflammation A method for the detection of the presence of inflammation in a patient by measuring the amount of circulating intercellular adhesion molecule (cICAM-1) in a sample of one or more bodily fluids of the patient and then comparing the amount of cICAM-1 in th... | 12/05/1995 |
| 5466611 | Method for the determination of antigens or antibodies in the presence of an immune complex The invention relates to a latex agglutination method for the detection or determination of one partner of an antigen-antibody reaction, wherein, in order to suppress non-specific reactions, to, for example, Clq and rheumatoid factors the immunochemical r... | 11/14/1995 |
| 5378637 | Method for measuring hyaluronic acid A method for measuring hyaluronic acid in a biological sample which comprises (a) coating a solid support with hyaluronic acid; (b) incubating the sample with cartilage proteoglycan; (c) exposing the incubated sample to the coated solid support; (d) then ... | 01/03/1995 |
| 5354691 | Polypeptides and derivatives thereof as well as their use in pharmaceutical and diagnostic compositions A polypeptide having amino acid sequence 172-192 of a Mycobacterium bovis BCG 64 kD polypeptide, said sequence having the formula ##STR1## as well as polypeptides derived therefrom, in the amino acid sequence of which sequence 172-179 and/or sequence... | 10/11/1994 |
