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| Number | Title | Issue Date |
| 8183046 | Temperature resistant pH buffers for use at low temperatures A method for preparing a composition that includes selecting a pH of the composition; selecting a first buffer with a negative temperature coefficient; selecting a second buffer with a positive temperature coefficient; and forming the composition comprising the firs... | 05/22/2012 |
| 7422903 | Multi-analyte reference solutions The present invention provides a reference solution for use in instruments that determine hematocrit levels in biological samples by measuring the resistance and/or conductivity of the biological samples. A reference solution according to the invention achieves cond... | 09/09/2008 |
| 7416891 | Reagent and method for classifying leucocytes A reagent for classifying leucocytes, including: a) at least one of surfactant selected from a cationic surfactant, an amphoteric surfactant, and the combination thereof; b) an organic compound having phenyl or heterocyclic group, wherein when the surfactant is a ca... | 08/26/2008 |
| 7413905 | Reagents and methods for classifying leukocytes The present invention relates to a reagent for classifying leukocytes including (a) at least one surfactant capable of lysing erythrocytes and partly damaging the cell membrane of leukocytes, (b) at least one organic compound bearing an anionic group capable of bind... | 08/19/2008 |
| 7390663 | Process, composition and kit for providing a stable whole blood calibrator/control The present invention is directed toward a stable calibrator and/or control, kit and process for using in a glucose monitoring instrumentation. Principally, the instant invention teaches a glycolyzed red blood cell component which has been treated with a glycolysis ... | 06/24/2008 |
| 7387880 | Method for monitoring resting and activated platelets in unfixed blood samples The amount of platelet surface proteins in a sample may be measured by collecting a sample containing platelets into a collection tube containing a platelet stabilizing composition, labeling the platelet surface protein and detecting by cytometry. ... | 06/17/2008 |
| 7368132 | Glyoxal/zinc fixative This invention provides compositions and methods for fixing a biological sample, particularly fecal samples for diagnosis of parasitic infection. The fixative composition of the present invention comprises glyoxal (pyruvate aldehyde) and zinc sulfate and permits sta... | 05/06/2008 |
| 7361513 | Cellular controls for glycated hemoglobin Hb A1c Disclosed are cellular hemoglobin A1c (Hb A1c) normal and abnormal (high) controls for use in detecting Hb A1c levels. The present invention also relates to methods for generating cellular Hb A1c controls using red blood cells and methods for using the cellular cont... | 04/22/2008 |
| 7338809 | Method for assaying whole blood In a method for measuring an analyte, which comprises a reaction step of forming a reaction system including a sample containing whole blood, a first substance carried by a solid carrier and specifically binding to an analyte contained in the sample and a second sub... | 03/04/2008 |
| 7332295 | Multidimensional leukocyte differential analysis This invention relates to an improved procedure for the multiparameter analysis of leukocyte subpopulations from peripheral blood, bone marrow or any body fluid containing blood nucleated cells, including the quantification of each subpopulation in terms of cells pe... | 02/19/2008 |
| 7326577 | Cell fixation and use in phospho-proteome screening A new method of cell fixation using a mild denaturing heat and the fixative PERMIFLOW™ or similar fixative that preserves cell morphology, light scatter profiles, nucleic acid content, cell surface epitopes and unmasks internal epitopes previously not available. T... | 02/05/2008 |
| 7306950 | Composition and use of substances for stabilising amino acids containing sulphur The invention relates to a composition for the stabilization of sulphur-containing amino acids and/or for the inhibition of the continuous formation of sulphur-containing amino acids in withdrawn blood, to the use of suitable substances and compositions therefor as ... | 12/11/2007 |
| 7303920 | Staining reagent for staining hematology samples in an automated staining apparatus Automated staining equipment that can mix reagents is used to spray a Romanowsky stain onto slide mounted specimens which are then briefly centrifuged. The centrifugation step removes excess stain leaving only a thin film. Depending on the time of the centrifugation... | 12/04/2007 |
| 7294512 | Solution for calibrating a chemical analyzer for alcohol, carbonate and ammonia assays A multi-analyte calibration solution having known amounts of sodium carbonate, ammonium bicarbonate, and ethyl alcohol, with pH adjusted within a range between about 7.8 and 8.4. ... | 11/13/2007 |
| 7294307 | Apparatus for pumping and directing fluids for hematology testing An apparatus is provided for hematology testing, which has a sensing unit defining a counting orifice for the flow of a blood sample through the counting orifice to analyze the blood sample, and a pump unit having three syringes. A first syringe is coupled in fluid ... | 11/13/2007 |
| 7288410 | Assay buffer, compositions containing the same, and methods of using the same Compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the invention relates to the use of novel combinations of reagents to provide improved assay performance. ... | 10/30/2007 |
| 7285418 | Method and kit for the diagnosis of troponin I The invention provides a method for assaying for troponin I in a sample such as serum, the method comprising a determination of the troponin I concentration in a sample using a standard preparation that comprises a complete native troponin complex. One exemplary ass... | 10/23/2007 |
| 7279136 | Metering technique for lateral flow assay devices A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. A sample membrane is utilized having a collection region and a detection region, the collection region having a known saturation volume for the intended test ... | 10/09/2007 |
| 7244618 | Stable lipid standards The invention describes materials useful for calibrating methods, and standards, calibration verification, linearity, and quality control materials for any method used to detect lipids and/or lipoproteins. This invention describes methods for producing, and composit... | 07/17/2007 |
| 7235391 | Formulation of adenovirus for gene therapy The present invention addresses the need to improve the long-term storage stability (i.e. infectivity) of vector formulations. In particular, it has been demonstrated that for adenovirus, the use of bulking agents, cryoprotectants and lyoprotectants imparts desired ... | 06/26/2007 |
| 7223413 | Organ arrest, protection and preservation The present invention relates to a method for arresting, protecting and/or preserving an organ which includes administering effective amounts of (i) potassium channel opener or agonist and/or an adenosine receptor agonist and (ii) local anaesthetic to a subject in n... | 05/29/2007 |
| 7220747 | Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer This invention provides methods for treating cellular blood components and other cells containing mitochondria to improve vital qualities of the cells by contacting the cells with a mitochondrial enhancer to the cells. Mitochondrial enhancers prevent damage to and r... | 05/22/2007 |
| 7208166 | Use of botuline toxin to obtain a product to be used in articular pathologies, particularly coxarthrosis, epicondylitis and rotator muscle cap pathology Use of botulin toxin to obtain a product intended to be administered intramuscular with lissive effect in treating articular pathologies, particularly coxarthrosis, or arthrosis of the hip, epicondylitis of the elbow and rotator muscle cap pathology of the shoulder.... | 04/24/2007 |
| 7202090 | Hardness measurement reagent To provide a hardness measurement reagent unaffected by an M alkalinity in hardness measurement. A hardness measurement reagent as a one-solution type reagent includes a dye chosen from Eriochrome Black T (EBT) and Calmagite, triethanolamine, a glycol compound, and ... | 04/10/2007 |
| 7202087 | Anticoagulant composition A solid heparin tablet composition has a melting point of 25° C. or higher and is a continuous lipid component containing one or more polar lipids, one or more non-polar lipids, optionally one or several of water and mono- to trivalent alcohol in an amount of up to... | 04/10/2007 |
| 7195923 | Ratiometric determination of glycated protein The present invention provides methods for determining a ratio of an amount of a glycated form of a protein to a total amount of the protein in a sample containing the glycated protein, the glycosylated protein, or the glycoprotein. The method incorporates lateral f... | 03/27/2007 |
| 7192776 | Synthetic urine and method of manufacturing same A synthetic urine solution and method of its manufacture are disclosed. The solution includes water having a pH between 3 and 10. The solution further includes creatinine and means for removing bacteria from the solution so as to control or eliminate sepsis of the u... | 03/20/2007 |
| 7176022 | Directly injectable formulations which provide enhanced cryoprotection of cell products This invention provides compositions and methods for cryoprotection of recombinant live cancer cells. Specifically, an improved cryoprotective medium is provided which includes a hydroxyethyl starch and/or derivative thereof alone or in combination with either DMSO ... | 02/13/2007 |
| 7172902 | Quality control material for reagentless measurement of analytes A method of monitoring calibration of a spectrophotometric apparatus that includes one or more than one calibration algorithm for one or more than one analyte, involves measuring absorbance of a quality control material with the apparatus to obtain a measurement, ca... | 02/06/2007 |
| 7169547 | High concentration white blood cells as a therapeutic product A therapeutic product formed from a high concentration of white blood cells having a high degree of cell viability. The white blood cells are sequestered from their normal population presence in whole blood by placing the blood into a container and preventing coagul... | 01/30/2007 |
| 7157282 | Quality control material for reagentless measurement of analytes A method of monitoring calibration of a spectrophotometric apparatus having one or more than one calibration algorithm for one or more than one analyte. This method involves measuring an absorbance of a quality control material to obtain a measurement, calculating o... | 01/02/2007 |
| 7156997 | Package assembly for piperazine-based membranes A package assembly comprising a sealed water-impermeable bag enclosing: a spiral wound filtration element comprising a piperazine-based membrane, and an aqueous solution comprises a substantially non-oxidizable buffer having capacity to sequester at least 0.0025 mol... | 01/02/2007 |
| 7148067 | Thromboplastin reagents A thromboplastin reagent includes tissue factor, Factor VIIa, and a net negatively charged phospholipid. The thromboplastin reagent is a synthetic thromboplastin reagent, and is in dried form. ... | 12/12/2006 |
| 7138226 | Preservation of RNA and morphology in cells and tissues A solution for preservation and/or storage of a cell or tissue is described. This simple nonaqueous composition can have 10% polyethylene glycol and 90% methanol. It can be used at room temperature. Special chemicals, equipment, and techniques are not needed. Tissue... | 11/21/2006 |
| 7135341 | Reference control containing a nucleated red blood cell component A method of making a reference control containing a nucleated red blood cell component includes providing a blood cell containing a nucleus; treating the blood cell with a treatment solution to alter a nucleus property from a natural value to a target value suitable... | 11/14/2006 |
| 7106889 | Image analysis systems and devices for use therewith An image analysis system for automated reading of printed multi-character codes, for example on antibiotic susceptibility testing disks, makes use of an orientation means, for example an underline printed beneath the code, to bring the code or its image into canonic... | 09/12/2006 |
| 7094601 | Microinjection of cryoprotectants for preservation of cells A preservation method for biological material having cell membranes includes microinjecting the cells with sugar; preparing the cells for storage; storing the biological material; and recovering the stored biological material from storage. The invention also feature... | 08/22/2006 |
| 7094378 | Method and apparatus for inactivation of biological contaminants using photosensitizers Methods and apparatuses for treating fluids to inactivate microorganisms which may be present therein, said fluid containing one or more components selected from the group consisting of protein, blood and blood constituents are provided. The methods comprise adjusti... | 08/22/2006 |
| 7049110 | Inactivation of West Nile virus and malaria using photosensitizers Methods and apparatuses are provided for inactivation of microorganisms in fluids or on surfaces. Preferably the fluids contain blood or blood products and comprise biologically active proteins. Preferred methods include the steps of adding an effective, non-toxic a... | 05/23/2006 |
| 7045279 | Isolated perfused heart preparation and method of use An isolated heart preparation in which essentially normal pumping activity of all four chambers of the heart is preserved, allowing for the use of the preparation in conjunction with investigations of electrode leads, catheters, cardiac implants and other medical de... | 05/16/2006 |
