...Chester Carlson was a patent agent who tired of having to make multiple copies of patent applications using the only duplication method available at the time: carbon paper. In 1959 he came up with a new copying system and took it to IBM for evaluation. The "experts" at IBM determined potential sales to be only 5,000 units because people wouldn't want to use a bulky machine when they had carbon paper. Carlson's invention was the xerography process, the company founded on the system is Xerox.
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| Number | Title | Issue Date |
| 8183053 | Preconcentrator media and methods for preconcentration of an analyte The present invention provides improved preconcentrator media suitable for selectively desorbing captured analytes. Additionally, the current invention provides improved methods for concentrating trace quantities of analytes to a degree suitable for detection by a d... | 05/22/2012 |
| 8183054 | Instrument and method for collecting nucleic acids An instrument and a method for conveniently collecting nucleic acids from a biological nucleic acid-containing sample are provided. A nucleic acid-capturing tip having silica-containing solid phases enclosed therein in such a state as being capable of coming into co... | 05/22/2012 |
| 8148169 | Method and device for extracting an analyte The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a ... | 04/03/2012 |
| 8148168 | Method and device for sample preparation The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a ... | 04/03/2012 |
| 7989215 | Methods and systems for adding a reagent to an analyte in a gel The present invention relates to methods and systems for adding a reagent to an analyte in a gel. The invention further provides methods and systems for transferring liquid analyte reagent mixtures from a gel to a second vessel, such as a microtitre plate. The inven... | 08/02/2011 |
| 7960182 | Affinity adsorbents for Factor VIII and von Willebrand's Factor For the separation, removal, isolation, purification, characterization, identification or quantification of Factor VIII, von Willebrand's Factor or a protein that is a analogue of either, an affinity adsorbent is used that is a compound of formula (II) wherein one X... | 06/14/2011 |
| 7943393 | Method and device for extracting an analyte The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a ... | 05/17/2011 |
| 7879621 | Open channel solid phase extraction systems and methods The invention provides, inter alia, methods, devices and reagents for the preparation of native and non-denatured biomolecules using solid-phase extraction channels. The invention is particularly suited for the purification, concentration and/or analysis of protein ... | 02/01/2011 |
| 7875462 | Method and device for sample preparation The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a ... | 01/25/2011 |
| 7820451 | Analytical test element An analytical test element for determining at least one analyte in a liquid is provided comprising a support, at least one detection element, and a channel capable of capillary liquid transport which is at least partially formed by a hydrophilic network, one side of... | 10/26/2010 |
| 7776616 | Apparatuses and methods for isolating nucleic acid The present invention is an apparatus and method for purifying and isolating nucleic acid. The system uses one or more automated stations to perform steps of the method, including loading a sample onto a solid support in a processing container, purifying the sample,... | 08/17/2010 |
| 7776615 | Method for solid-phase micro extraction and apparatus therefor The present invention is directed to a system for pre-treatment of a sample to be introduced in a chromatograph, and a method for performing solid-phase extraction of a component present in a sample. The system uses a syringe having a needle being provided with a po... | 08/17/2010 |
| 7767467 | Coaxial tubular sequestering device for micro spheres and cells A device for the separation of small particles or cells from a fluid suspension of the same is described. The device includes a coaxial tubular design in which the inner tube is a micro porous tube that allows the passage of liquids and certain particulates up to a ... | 08/03/2010 |
| 7709267 | System and method for extracting headspace vapor A system and method for extracting headspace vapor is generally disclosed comprising pressurizing a vessel containing headspace vapor with a carrier gas and subsequently venting the sample mixture through an adsorbent trap and out a vent. A flow controller is employ... | 05/04/2010 |
| 7674631 | Method and device for solid phase microextraction and desorption A device for carrying out solid phase microextraction on-site is a tubular member having one closed end and one open end with an extracting surface within said tubular member. The extracting surface can be an extracting phase coating extending over a zone within the... | 03/09/2010 |
| 7666686 | Method for sample preparation by solid phase extraction An method for sample preparation using solid phase extraction. Using an apparatus comprising a SPE cartridge and a sorbent-containing gas filter which contains a sorbent and is detachably connected to the SPE cartridge the gas used to dry the SPE cartridge is purifi... | 02/23/2010 |
| 7651866 | Purge and trap concentrator with electrically adjusted purge flow A purge and trap concentrator has a sample processing system that includes a network of fluid passageways and fluid control devices. A flow controller couples to a purge gas inlet provides an electrically adjustable purge gas flow rate as a function of an electrical... | 01/26/2010 |
| 7625762 | Coaxial tubular sequestering device for micro spheres and cells A device for the separation of small particles or cells from a fluid suspension of the same is described. The device includes a coaxial tubular design in which the inner tube is a micro porous tube that allows the passage of liquids and certain particulates up to a ... | 12/01/2009 |
| 7605003 | Use of biomarkers for detecting ovarian cancer The present invention relates to a method of qualifying ovarian cancer status in a subject comprising: (a) measuring at least one biomarker in a sample from the subject and (b) correlating the measurement with ovarian cancer status. The invention further relates to ... | 10/20/2009 |
| 7517698 | Installation and process for automatic preparation of samples An installation for the automatic preparation of specimens by liquid/solid extraction on a column is characterized in that the extraction device comprises, on either side of the columns (3), a valve (4) controllable to switch one column (3) to t... | 04/14/2009 |
| 7491549 | Apparatus for desorption and ionization of analytes This invention relates generally to methods and apparatus for desorption and ionization of analytes for the purpose of subsequent scientific analysis by such methods, for example, as mass spectrometry or biosensors. More specifically, this invention relates to the f... | 02/17/2009 |
| 7482169 | Low dead volume extraction column device The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The invention is characterized b... | 01/27/2009 |
| 7468281 | Hollow fiber membrane sample preparation devices Simultaneous sample purification, enrichment and analysis of pharmaceuticals, illicit drugs, pollutants, biotechnological products, synthetic organic reaction products and food/flavor ingredients from complex matrices can be performed using porous hollow fiber or po... | 12/23/2008 |
| 7445939 | Stable liquid membranes for liquid phase microextraction The invention provides devices and methods for performing liquid phase microextraction of at least one analyte from an aqueous sample, wherein the device comprises a liquid membrane comprising a fatty acid ester, a vegetable oil, a silicone oil, a nitroarylalkylethe... | 11/04/2008 |
| 7442341 | Cartridge retaining mechanism for nucleic acid extracting apparatus A cartridge retaining mechanism equipped in a nucleic acid extracting apparatus for extracting a nucleic acid, the mechanism comprising: a cartridge that comprises: a cartridge main body that has a cylindrical shape with a bottom, and the bottom is shaped in a funne... | 10/28/2008 |
| 7442665 | Preparation and screening of crystalline inorganic materials Methods and apparatus for the preparation and use of a substrate having an array of diverse materials in predefined regions thereon. A substrate having an array of diverse materials thereon is generally prepared by delivering components of materials to predefined re... | 10/28/2008 |
| 7431841 | Method for the extraction of components made from organic material The invention relates to a method for the extraction of components made from organic material, comprising the step of extraction with a single-phase mixture of 50 to 90 vol. % methanol and 50 to 10 vol. % water and optionally 0 to 40 vol. % of a further solvent or s... | 10/07/2008 |
| 7419831 | Method and apparatus for determination of water and for normal phase liquid chromatography A method for calibrating an analysis instrument, e.g., a gas chromatograph, for water analysis that includes four steps. The first step is to continuously remove water from a liquid that contains water to produce a liquid containing a reduced amount of water such as... | 09/02/2008 |
| 7413909 | Method and apparatus for desorption and ionization of analytes This invention relates generally to methods and apparatus for desorption and ionization of analytes for the purpose of subsequent scientific analysis by such methods, for example, as mass spectrometry or biosensors. More specifically, this invention relates to the f... | 08/19/2008 |
| 7407625 | Volume-differential water assay system using hydrophilic gel Systems and methods for measuring the moisture and sediment content of a petroleum sample. In one embodiment, a sample to be tested is collected in a field bottle. The sample from the field bottle is then transferred from the field bottle, and into and through a mea... | 08/05/2008 |
| 7405083 | Method and apparatus for purifying and desalting biological samples The subject invention provides a sample processing technique for purifying a biological or chemical sample. The invention is particularly well-suited to prepare a sample for mass spectrometry. The process is to be performed in an article having at least one well, in... | 07/29/2008 |
| 7404931 | Device for separating and discharging plasma The invention concerns plasma separation on a microliter scale. The method/system according to the invention is able to provide plasma in the range of several microliters within a very short time as it is required, for example, in modern analyses by carrier-bound te... | 07/29/2008 |
| 7399635 | Impurity measuring method for Ge substrates The present invention provides an impurity measuring method comprising the steps of dropping a drop of a first solution on the surface of a substrate to be measured, moving the drop dropped on the surface of the substrate so that the drop is kept in contact with the... | 07/15/2008 |
| 7393691 | SERS method and apparatus for rapid extraction and analysis of drugs in saliva The method and apparatus rapidly separate drugs and their metabolites from saliva and, in a continuous sequence of steps, rapidly detect, identify and quantify them through surface-enhanced Raman spectroscopy. ... | 07/01/2008 |
| 7393694 | Chemical and biological sampling device and kit and method of use thereof A self-contained, leak-proof sampling device and kit employing said device for collecting chemical and biological samples from various surfaces. The invention provides a sampling device and kit that may be employed to easily collect chemical and biological samples, ... | 07/01/2008 |
| 7393692 | SERS method for rapid pharmacokinetic analysis of drugs in saliva The method and apparatus rapidly separate drugs and their metabolites from saliva and, in a continuous sequence of steps, rapidly detect, identify and quantify them through surface-enhanced Raman spectroscopy. ... | 07/01/2008 |
| 7390666 | Methods and devices for measuring total polar compounds in degrading oils This invention relates to methods for determining whether or not to discard a sample of oil based on the presence of polar compounds in the oil and devices to be used therewith. In a preferred embodiment a test strip including an adsorbent affixed to a backing is sp... | 06/24/2008 |
| 7387899 | Saliva sample collection system Test kit whereby the sponge portion of kit is used to swab saliva. The saliva is then extracted from sponge by either squeezing it out or through the use of a centrifuge. The sponge portion of the kit is attached to a collection container when used in the centrifuge... | 06/17/2008 |
| 7384794 | Micro-devices and analytical procedures for investigation of biological systems Fibres with an extraction phase coated thereon in combination with a positioning device are described to perform adsorption of components of interest from an animal or animal tissue for the investigation of living systems. A number of interfaces to analytical instru... | 06/10/2008 |
| 7374726 | Chemical reactor In a chemical reactor, a gas and a liquid which are in trace volumes are used to produce air bubbles and thus increase the interface area between the gas and liquid, substantially enhancing the efficiency of reaction between the gas and liquid. The chemical reactor ... | 05/20/2008 |