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| Number | Title | Issue Date |
| 8137983 | Method of maintaining a protein concentration at a tangential flow filter The present invention describes a system and method for accurately measuring the concentration of a substance within a filter housing. A concentration sensor and a communications device are coupled so as to be able to measure and transmit the concentration of a part... | 03/20/2012 |
| 8114680 | Buffy coat separator float system and method A tube and float system for use in separation and axial expansion of the buffy coat includes a transparent or semi-transparent, flexible sample tube and a rigid separator float having a specific gravity intermediate that of red blood cells and plasma. The float incl... | 02/14/2012 |
| 8084272 | Amelioration of heterophile antibody immunosensor interference The invention is directed to methods and devices for reducing interference from heterophile antibodies in an analyte immunoassay. In one embodiment, the invention is to a method comprising the steps of (a) amending a biological sample such as a whole blood sample wi... | 12/27/2011 |
| 8084271 | Method and a device for treating microparticles Method for handling microparticles in such a manner, that at least two treatment steps are performed for microparticles in the same vessel without moving the particles to another vessel. There are organs in the device for changing the solution without having to move... | 12/27/2011 |
| 8057762 | Penetrable cap A cap having a core structure dimensioned to receive a pipette therethrough. The cap includes two axially aligned frangible seals that are affixed to the core structure in a spaced-apart relationship. The frangible seals are constructed so that air passageways are f... | 11/15/2011 |
| 8034628 | Apparatus and method for trapping bead based reagents within microfluidic analysis systems An on-chip packed reactor bed design is disclosed that allows for an effective exchange of packing materials such as beads at a miniaturized level. Also disclosed is a method of treating a sample within a microfluidic analysis system, comprising; providing a main ch... | 10/11/2011 |
| 8007743 | Multifunctional vacuum manifold A laboratory device design particularly for a multiplate format that includes a manifold wherein the position of the plate is not a function of gasket compression or vacuum rate applied. In one embodiment, the device has a modular design, wherein one or more removab... | 08/30/2011 |
| 7993607 | Device and method for separating and discharging plasma The invention concerns plasma separation on a microliter scale. The method/system according to the invention is able to provide plasma in the range of several microliters within a very short time as it is required, for example, in modern analyses by carrier-bound te... | 08/09/2011 |
| 7972869 | Method and device for collecting and transferring biohazard samples A method and system for collecting airborne particles and hydrating the collected particles for analysis. The airborne particles, which may be biological contaminants, are collected from a container containing one or more mailpieces. In the collection stage, a dry f... | 07/05/2011 |
| 7955863 | Microfluidic device and material manipulating method using same Microfluidic devices for manipulating relatively dense materials, such as colloidal rod particles, are provided. Microfluidic devices for separating a denser first material from a less-dense second material are provided. Methods of manipulating a relatively dense fi... | 06/07/2011 |
| 7939034 | Method and tool for collecting blood plasma According to a blood plasma collection tool of the present invention, a phenomenon that blood cells in blood spontaneously precipitate due to an effect of gravitational force takes place in the very narrow microspace (separation part) having the very narrow depth in... | 05/10/2011 |
| 7927563 | Kit for separation of biological fluids For containing a biological fluid and draining a constituent of the biological fluid, a kit includes a barrel, a piston assembly, a removable element, which is configured to move the piston assembly, a drainage element, which interacts with the piston assembly, and ... | 04/19/2011 |
| 7910378 | Methods for detection of hydrophobic drugs Methods and reagents are disclosed for pretreating a sample suspected of containing a hydrophobic drug for conducting an assay method for detecting the hydrophobic drug. A combination is provided in a medium. The combination comprises (i) the sample, (ii) a releasin... | 03/22/2011 |
| 7846742 | Method for detecting substance to be detected containing at least one component that is dispersible in air in the form of solid particles The invention relates to a method and apparatus for detecting substance to be detected. The apparatus comprises at least one sampling member for sampling air contained in a closed space, the sampling member comprising at least one filter presenting pore or mesh size... | 12/07/2010 |
| 7846743 | Uses of parylene membrane filters The invention provides parylene membrane filters, filter devices and methods of making them and using them in the mechanical separation of cells and particles by size. The provision of parylene membrane filters with high figures of merit and finely controlled hole s... | 12/07/2010 |
| 7833804 | Structure for introducing a plurality of solutions, micro fluidic device having said structure and method for introducing solution The present invention relates to a solution introducing structure for introducing a plurality of solutions (a sample and/or a reagent solution) in highly accurate volume, in high amount and simply, into a channel (1) of a micro fluidic device, said channel ( | 11/16/2010 |
| 7807476 | Vial system and method for processing liquid-based specimens A vial-based system and method for handling and processing specimens of particulate matter-containing liquid directly in the vial. A processing assembly, which includes a stirrer and a particulate matter separation chamber, is releasably coupled to the inside of the... | 10/05/2010 |
| 7767466 | Sample filtering method using sample collecting container, jig and sample collecting container A method for filtrating liquid sample such as blood or the like with a filter member utilizing inner vacuum, the same enabling completion of filtration without removing a stopper, and superior in safety and being free from contamination. In collecting and fil... | 08/03/2010 |
| 7736907 | Device for collecting blood and separating blood constituents, method for separating blood constituents and use of said device A device and a method for collecting blood and separating blood plasma as a liquid sample using a channel that absorbs the liquid sample by capillary forces. To obtain a uniform filling of the channel with the liquid sample and an effective separation, deaeration ta... | 06/15/2010 |
| 7700368 | Methods of purifying cannabinoids from plant material The invention relates to methods of preparing cannabinoids in substantially pure form starting from plant material. Also described are substantially pure preparations of various cannabinoids and cannabinoid acids, and also extracts enriched in cannabinoids and canna... | 04/20/2010 |
| 7700369 | Method and apparatus for applying a pressure differential to a multi-well plate A method and apparatus for moving material in a multi-well plate includes applying positive and negative pressure to one or more wells in the plate, e.g., to enhance a flow rate of material from the well through a filter element. Wells requiring application of posit... | 04/20/2010 |
| 7674630 | Method and device for separating particles The invention relates to a method and a device for separating particles using ultrasonic standing waves which are switched between two different frequencies. A second order harmonic standing wave is used together with the fundamental standing wave. If the particles ... | 03/09/2010 |
| 7651865 | Conditioning slurry samples for quantitative instrumental analysis A method and system to consistently and automatically conditioning and delivering a solid-free liquid (filtrate) sample suitable for instrumental analysis is disclosed. A slurry, preferably a slurry produced by a sub-atmospheric pressure chlorate dioxide generating ... | 01/26/2010 |
| 7638342 | Spectrophotometric analysis of plasma in a closed-container The present invention provides a method of analyzing plasma from a sample of whole blood. The method includes a) obtaining a sample of whole blood from a subject in a container, the container having a first end and a second end, the first end of the container for re... | 12/29/2009 |
| 7629176 | Buffy coat separator float system and method A tube and float system for use in separation and axial expansion of the buffy coat includes a transparent or semi-transparent, flexible sample tube and a rigid separator float having a specific gravity intermediate that of red blood cells and plasma. The float incl... | 12/08/2009 |
| 7611903 | System for trapping and storing gases for subsequent chemical reduction to solids A system for quantitatively reducing oxide gases. A pre-selected amount of zinc is provided in a vial. A tube is provided in the vial. The zinc and the tube are separated. A pre-selected amount of a catalyst is provided in the tube. Oxide gases are injected into the... | 11/03/2009 |
| 7601545 | Automated macromolecule sample preparation system An apparatus for preparing a macromolecule sample from a complex liquid mixture includes a hydraulic system adapted for control by an automated controller, comprising a pump and one or more valves. The hydraulic system can be controlled by an automated controller to... | 10/13/2009 |
| 7598089 | Methods and compositions for separating cells The invention provides compositions and methods for cell separation. These reagents and techniques specifically agglutinate cells via surface antigen recognition and can be used to recover rare cell types in high yield. ... | 10/06/2009 |
| 7595199 | Method of detecting amyloid-like fibrils or protein aggregates The present invention relates to methods of detecting the presence of detergent- or urea-insoluble amyloid-like fibrils or protein aggregates on filters. Preferably, said fibrils or aggregates are indicative of a disease, preferably of a neurodegenerative disease su... | 09/29/2009 |
| 7537935 | System for providing biological materials A process and closure arrangement is provided for isolating purified biological material. The process includes placing biological materials in separate lysis vessels, adding lysis liquids to the biological materials in the lysis vessels, and transferring the liquids... | 05/26/2009 |
| 7534623 | Apparatus and method for the purification of nucleic acids The present invention is directed to novel device comprising a sol-gel filled microchannel and methods for purifying nucleic acids from biological samples. In one embodiment shown in FIG. 1, the microfluidic device (1) comprises a base (2) with ... | 05/19/2009 |
| 7521256 | Method and a device for defining a small volume of a liquid sample A method and a device for separating a small defined volume of a liquid sample from a relatively large undefined volume of the sample. In a surface of a first body (10) at least one cavity (12) having said small defined volume is provided. The relative... | 04/21/2009 |
| 7498174 | Kinetic microplate with temporary seals A microplate assembly comprising a multi-well microplate and a plurality of reagent wells proximal the multi-wells. The microplate includes a frame that houses a plurality of open wells in a rectangular array. Reagent wells mounted within the microplate to react wit... | 03/03/2009 |
| 7498175 | Method and apparatus for determining temperature of and controlling the evaporation of liquid samples A method is described for evaporating liquid samples contained in sample holders mounted within a chamber and rotated by the rotor during an evaporation process in which the pressure in the chamber is reduced below atmospheric and the sample holders are rotated at h... | 03/03/2009 |
| 7491548 | Method and device for collecting and transferring biohazard samples A method and system for collecting airborne particles and hydrating the collected particles for analysis. The airborne particles, which may be biological contaminants, are collected from a container containing one or more mailpieces. In the collection stage, a dry f... | 02/17/2009 |
| 7488603 | Method and device for extracting an analyte The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a ... | 02/10/2009 |
| 7476547 | Cell separation compositions and methods The invention provides compositions and methods for cell separation. These reagents and techniques specifically agglutinate cells via surface antigen recognition and can be used to recover even rare cell types in high yield. ... | 01/13/2009 |
| 7470545 | Buccal dissolution of active substances Equipment and method of use for in vitro buccal dissolution testing. The invention is particularly useful for evaluating the effect of taste-masking in oral dosage forms. ... | 12/30/2008 |
| 7442556 | Microfluidic-based electrospray source for analytical devices with a rotary fluid flow channel for sample preparation This invention provides microfluidic devices and methods for using the same. Microfluidic devices of the present invention comprises a first elastic layer, a fluid flow channel within the elastic layer; and a means for providing a fluid sample from the fluid flow ch... | 10/28/2008 |
| 7438856 | Microfluidic devices and methods Embodiments of the invention are directed to microfluidic devices. In one embodiment, a microanalysis chip comprises a body having at least one transfer-separation channel with a channel bottom that has a bottom opening. The transfer-separation channel terminates in... | 10/21/2008 |
