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| Number | Title | Issue Date |
| 8026106 | Removal of mercuric chloride crystals from fixed tissues Mercuric chloride precipitates are removed from biological cell samples fixed with mercuric chloride and held in an embedding media, by contacting the biological cell samples with an aqueous solution containing a surfactant, and incubating at a temperature in excess... | 09/27/2011 |
| 7858392 | Method and apparatus for processing of biological samples for mass spectrometry analysis A system and corresponding method for processing of biological samples prior to spectroscopy analysis. The system includes a support for an organic sample, a solution applicator configured to apply a solution for extraction of at least one biomarker protein from the... | 12/28/2010 |
| 7807475 | Process for producing surface enhanced membrane A membrane having a refined surface as well as to a process and an apparatus for producing such a membrane, and which is useful, in particular, for rapid diagnostic tests for identifying specific analytes in liquid media. ... | 10/05/2010 |
| 7767465 | Reduction of platelet interference in plasma assay samples The present invention relates to compositions for improving assay accuracy for plasma samples by decreasing or eliminating false results due to platelet interference. The compositions of the present invention comprise compositions that include a platelet interferenc... | 08/03/2010 |
| 7632686 | High sensitivity quantitation of peptides by mass spectrometry The instant invention provides an economical flow-through method for determining amount of target proteins in a sample. An antibody preparation (whether polyclonal or monoclonal, or any equivalent specific binding agent) is used to capture and thus enrich a specific... | 12/15/2009 |
| 7563622 | Molybdenum complex and test kit to enhance accuracy of analysis of endogenous analytes in biological fluids Methods for enhancement in accuracy of immunochemical analysis of heterogeneous biological fluids containing exogenous substances that can interfere in immunochemical analysis for endogenous analytes of interest. According to this method a heterogeneous biological f... | 07/21/2009 |
| 7442516 | Antibody specific to central nervous system tau protein The present invention provides an antibody which specifically recognizes a CNS tau protein but not a peripheral tau protein. More specifically, the present invention provides an antibody obtainable by using a polypeptide comprising an amino acid sequence of a connec... | 10/28/2008 |
| 7442556 | Microfluidic-based electrospray source for analytical devices with a rotary fluid flow channel for sample preparation This invention provides microfluidic devices and methods for using the same. Microfluidic devices of the present invention comprises a first elastic layer, a fluid flow channel within the elastic layer; and a means for providing a fluid sample from the fluid flow ch... | 10/28/2008 |
| 7442555 | Ammonia gas sensor method and device A mixed potential sensor device and methods for measuring total ammonia (NH3) concentration in a gas is provided. The gas is first partitioned into two streams directed into two sensing chambers. Each gas stream is conditioned by a specific catalyst syste... | 10/28/2008 |
| 7439070 | Waste material handling, sampling and metal content value calculation A bulk sample is fed with a liquid into a mixing tank (1) where it is stirred to form a dispersion. A proportion of the dispersion is recycled from the bottom of the tank through a line to the top of the tank so that at least the dispersion in the recycle loo... | 10/21/2008 |
| 7419831 | Method and apparatus for determination of water and for normal phase liquid chromatography A method for calibrating an analysis instrument, e.g., a gas chromatograph, for water analysis that includes four steps. The first step is to continuously remove water from a liquid that contains water to produce a liquid containing a reduced amount of water such as... | 09/02/2008 |
| 7419835 | Screening for ligand binding at specific target sites A method for screening of compounds for binding differentiation at various drug target binding sites is used with a device measuring the enthalpy of reaction for the binding. The method includes merging test ligand with target compound and merging test ligand with t... | 09/02/2008 |
| 7416897 | Method for high-throughput screening assay sample preparation and analysis A method is disclosed for high-throughput screening assay sample preparation and testing for the identification of binding between drug targets and library compounds, for use with a calorimetric device measuring the enthalpy of reaction for the binding. The method i... | 08/26/2008 |
| 7413905 | Reagents and methods for classifying leukocytes The present invention relates to a reagent for classifying leukocytes including (a) at least one surfactant capable of lysing erythrocytes and partly damaging the cell membrane of leukocytes, (b) at least one organic compound bearing an anionic group capable of bind... | 08/19/2008 |
| 7410753 | Removal of embedding media from biological samples and cell conditioning on automated staining instruments The present invention provides reagents for use in an automated environment for removing or etching embedding media by exposing a biological sample to be stained in histochemical or cytochemical procedures without the dependence on organic solvents. The reagents com... | 08/12/2008 |
| 7405036 | Process for reducing pathogens in a biological sample and removing a sample pellet from a sample tube The present invention is directed towards an apparatus and method for disinfecting biological samples, including semen and the like, and for removing a biological sample pellet from surrounding media while reducing the risk of recontamination of the pellet with said... | 07/29/2008 |
| 7405047 | Method for estimation of the amount of specific cell types The present invention relates to the estimation of the amount of subtypes of specific cells, for example the number of certain subtypes of leukocytes, by measurements of unique proteins in extracts of blood and other biological material. The knowledge of the number ... | 07/29/2008 |
| 7405083 | Method and apparatus for purifying and desalting biological samples The subject invention provides a sample processing technique for purifying a biological or chemical sample. The invention is particularly well-suited to prepare a sample for mass spectrometry. The process is to be performed in an article having at least one well, in... | 07/29/2008 |
| 7396688 | Mass spectrometric analysis of biopolymers The present invention makes use of unique tags of a specific biopolymer that can be exploited for determining the concentration the biopolymer in crude solutions. In preferred embodiments the biopolymer is either a protein or a polynucleotide. Particularly, the inve... | 07/08/2008 |
| 7390677 | Immunoassay and immunoassay apparatus An immunoassay comprises the steps of: (a) mixing a whole blood sample with sensitized insoluble carrier particles smaller than erythrocytes to cause an immune agglutination reaction; (b) introducing the resulting immune agglutination reaction mixture including aggl... | 06/24/2008 |
| 7384791 | Method of analyzing blood A method of analyzing blood includes delivering a blood sample to a test device, applying a spatially varying electric field to the blood sample to provide a depleted cell concentration in a portion of the blood sample, and sensing a property of the portion of the b... | 06/10/2008 |
| 7374951 | System and apparatus for use in detecting microorganisms A system and an apparatus for use in detecting a target microorganism or agent is disclosed which involves a solid support carrying a binding partner specific for the particular microorganism or agent and the solid support being characterised in that it defines mean... | 05/20/2008 |
| 7361479 | Assay The present invention provides a method of determining the presence or amount of newly synthesized antibody in a sample in response to an immunogen by detecting the released antibodies or parts thereof in a sample containing lymphocytes which have been disrupted whe... | 04/22/2008 |
| 7361513 | Cellular controls for glycated hemoglobin Hb A1c Disclosed are cellular hemoglobin A1c (Hb A1c) normal and abnormal (high) controls for use in detecting Hb A1c levels. The present invention also relates to methods for generating cellular Hb A1c controls using red blood cells and methods for using the cellular cont... | 04/22/2008 |
| 7348157 | Immunoassay A method for detection and/or quantification of cardiac troponin I (cTnI) in a sample derived from an individual's blood, the method being based on a sandwich immunoassay employing at least two capture antibodies and at least one tracer antibody, in which a first ca... | 03/25/2008 |
| 7347976 | Methods and devices for removal of organic molecules from biological mixtures using a hydrophilic solid support in a hydrophobic matrix Methods and devices for removing small negatively charged molecules from a biological sample mixture that uses a solid-phase extraction material that includes a hydrophilic solid support at least partially embedded within a hydrophobic matrix. ... | 03/25/2008 |
| 7344890 | Method for discriminating platelets from red blood cells A method for discriminating and quantifying platelets within an analyzed blood sample involves initially diluting the blood sample with a ghosting reagent that causes a change in the index of refraction of the red blood cells. Owing to the change in the index of ref... | 03/18/2008 |
| 7332346 | Method of collecting chemically contaminating impurity constituents contained in air The method is intended to detect with high sensitivity and high accuracy chemically contaminating impurities in which there exist chemically contaminating impurity constituents of basic series, acidic series, and organic substance series, in gaseous and particle sta... | 02/19/2008 |
| 7326577 | Cell fixation and use in phospho-proteome screening A new method of cell fixation using a mild denaturing heat and the fixative PERMIFLOW™ or similar fixative that preserves cell morphology, light scatter profiles, nucleic acid content, cell surface epitopes and unmasks internal epitopes previously not available. T... | 02/05/2008 |
| 7326386 | Apparatus for extracting nucleic acid The apparatus for extracting nucleic acid includes a cartridge holder 61 which holds nucleic acid extraction cartridges 11, a container holder 62 which holds waste liquid containers 12 and recovering containers 13 and a container h... | 02/05/2008 |
| 7323144 | Apparatus for separating biological sample and separating method of the same A simplified collecting operation of a biological sample is provided, which enables reduction of the examination cost. The invention comprises a biological sample collecting means 2 for receiving a collected biological sample, a filtering means 21 for ... | 01/29/2008 |
| 7323344 | Method of measuring the concentration of hydrogen and methane in nitrogen by ion mobility spectrometry A method is provided for the quantitative analysis of the contents, in nitrogen, of hydrogen and methane by ionic mobility spectrometry. The method includes the steps of: a) performing a measurement of the apparent hydrogen concentration in the nitrogen to be analyz... | 01/29/2008 |
| 7323342 | Method for improving oil desalting by forming unstable water-in-oil emulsions A method for determination for a given oil the relative stability of a water-in-oil emulsion that will be formed by that oil with water comprises measuring for the given oil the weight fraction of the oil that is most strongly adsorbed on a silica gel column success... | 01/29/2008 |
| 7309608 | Method of analysis of aldehyde and ketone by mass spectrometry A method of identification and quantitative analysis of aldehydes and/or ketones in a sample by mass spectrometry using stable isotope labeled oxime internal standards or stable isotope labeled hydrazone internal standards is provided. Stable isotope labeled oxime i... | 12/18/2007 |
| 7297549 | Method of determining measurement bias in an emissions monitoring system A method of determining bias in a measurement of a constituent concentration level in a sample gas is provided. The method comprises establishing a sample gas flow from an emission stream into a sample gas line of an emissions monitoring system. The method further c... | 11/20/2007 |
| 7297551 | Recombinant proteins and peptides for endotoxin biosensors, endotoxin removal, and anti-microbial and anti-endotoxin therapeutics Recombinant fragments of Factor C are disclosed. These proteins and peptides show great potency in recognizing, binding to, neutralizing and removing endotoxin. These molecules can thus be used for anti-microbial, anti-endotoxin, and anti-sepsis therapy. SSCrFCES is... | 11/20/2007 |
| 7259020 | Microfabricated structures for facilitating fluid introduction into microfluidic devices Fluid introduction is facilitated through the use of a port which extends entirely through a microfluidic substrate. Capillary forces can be used to retain the fluid within the port, and a series of samples or other fluids may be introduced through a single port by ... | 08/21/2007 |
| 7244395 | Apparatus for trace sulfur detection using UV fluorescence A method and system for performing low level sulfur UV fluorescence measures including an UV interference reduction system which removes or destroys interfering nitrogen oxides. The preferred nitrogen removal systems include introducing ozone into the system in suff... | 07/17/2007 |
| 7238532 | Isothiazolone monitoring in aqueous systems A method for measuring the concentration of isothiazolones in aqueous systems including removing sample interferences by lowering the pH of a sample collected from the aqueous system containing isothiazolones and filtering the sample, removing additional interferenc... | 07/03/2007 |
| 7226562 | Liquid analysis cartridge The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of particle capture regions. The storage channel is preferably an isotropic spa... | 06/05/2007 |
