Bizarre Patents
Pizza Pie With Concentric Rings of Crust
A pizza mold for forming a plurality of concentric raised ridges of dough (i.e., crust) on the surface of a pizza pie.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8188011 | Optimization of ligand affinity for RNA targets using mass spectrometry The present invention provides methods for the identification ligand compounds that bind to target molecules such as proteins or structured RNA with as little as millimolar (mM) affinity using mass spectrometry. The methods may be used to determine the mode of bindi... | 05/29/2012 |
| 8187893 | Mass spectrometric based assay for presence of a protein without the use of a standard The present teachings provide methods for the development of a mass spectrometric based assay for a protein in a sample using parent-daughter ion transition monitoring (PDITM). In various aspects, the present teachings provide methods for developing a mass spectrome... | 05/29/2012 |
| 8173442 | Methods for detecting dihydroxyvitamin D metabolites by mass spectrometry Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a dihydroxyvitamin D metabolite in a sample and detecting the amount of the ion to determine the ... | 05/08/2012 |
| 8173441 | Method for applying NMR for ligand discovery or as a drug screening tool The present invention relates to a method for screening compounds to identify compounds that bind to a specific target, comprising the steps of: (a) providing a target immobilized to a solid support; (b) generating a first NMR spectrum of the said compounds to be sc... | 05/08/2012 |
| 8168440 | Polymeric sulfated surfactants for capillary electrophoresis (CE) and CE-mass spectrometry (CE-MS) The present invention relates generally to methods for enantiomeric separation of complex chemical mixtures using micelles of surfactant molecules that have a sulfate or sulfonate head group, a chiral selector, a linker, and a hydrophobic tail. Also provided are mic... | 05/01/2012 |
| 8168441 | Sample holder for MALDI mass spectrometric analysis, and mass spectrometric analysis method Used is a sample holder for MALDI mass spectrometry, which has a CuO secondary particle as a laser-beam-absorbing matrix and in which the secondary particle comprises an aggregate of CuO primary particles having an average particle diameter of 100 nm or smaller and ... | 05/01/2012 |
| 8153441 | Method for analyzing structure and purity of serotonin transporter imaging agent [I] ADAM and precursor SnADAM An analytical technique for determining the structures of serotonin transporter (SERT) imaging agent [123I] ADAM and its precursor, SnADAM by using a high-performance liquid chromatography tandem mass spectrometer (LC-MS/MS) is provided. An analytical tec... | 04/10/2012 |
| 8137982 | Mass spectrometry precursor ion selection The present invention is concerned with methods for the selection of precursor ions of a sample polypeptide for fragmentation in mass spectrometry, together with methods for determining at least one putative amino acid sequence for a sample polypeptide, apparatus an... | 03/20/2012 |
| 8119418 | Monitoring treatment of colorectal cancer patients with drugs targeting EGFR pathway using mass spectrometry of patient samples Methods using mass spectral data analysis and a classification algorithm provide an ability to determine whether a non-small-cell lung cancer patient, head and neck squamous cell carcinoma or colorectal cancer patient has likely developed a non-responsiveness to tre... | 02/21/2012 |
| 8119417 | Monitoring treatment of head and neck cancer patients with drugs EGFR pathway using mass spectrometry of patient samples Methods using mass spectral data analysis and a classification algorithm provide an ability to determine whether a non-small-cell lung cancer patient, head and neck squamous cell carcinoma or colorectal cancer patient has likely developed a non-responsiveness to tre... | 02/21/2012 |
| 8119416 | MALDI analysis using modified matrices with affinity groups for non-covalent binding with analytes Methods and compounds are provided to improve the desorption and ionization of analyte for mass spectrometry analysis. More specifically, it is for laser desorption/ionization mass spectrometry. The method uses photon energy absorbing molecules that can bind with an... | 02/21/2012 |
| 8101427 | Methods for detecting vitamin D metabolites by mass spectrometry Provided are methods of detecting the presence or amount of a vitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a vitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount... | 01/24/2012 |
| 8097468 | Using plasma proteomic pattern for diagnosis, classification, prediction of response to therapy and clinical behavior, stratification of therapy, and monitoring disease in hematologic malignancies The present invention demonstrates that the diagnosis and prediction of clinical behavior in patients with hematologic malignancies, such as leukemia, can be accomplished by analysis of proteins present in a plasma sample. Thus, in particular embodiments the present... | 01/17/2012 |
| 8097469 | Method and system for determining whether a drug will be effective on a patient with a disease A process of determining whether a patient with a disease or disorder will be responsive to a drug, used to treat the disease or disorder, including obtaining a test spectrum produced by a mass spectrometer from a serum produced from the patient. The test spectrum m... | 01/17/2012 |
| 8084269 | Methods for detecting dihydroxyvitamin D metabolites by mass spectrometry Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a dihydroxyvitamin D metabolite in a sample and detecting the amount of the ion to determine the ... | 12/27/2011 |
| 8080428 | Investigation of mucosa dryness conditions The present invention relates to diagnosis and/or treatment of medical conditions. The present invention relates to new method of diagnosing dry mucosa condition in a subject. The condition may be dry eye. The present invention also provides a method to monitor the ... | 12/20/2011 |
| 8076156 | Isotopic signature carbon tracing method to discern shellfish-based glucosamine from corn-based glucosamine A glucosamine sample is analyzed using an isotope ratio mass spectrometer to determine whether the glucosamine sample is corn-based, e.g., vegetable-based, as opposed to shellfish-based. The isotope ratio mass spectrometer yields an isotopic value for δ 13 | 12/13/2011 |
| 8076157 | Vitamin D metabolite determination utilizing mass spectrometry following derivatization The invention relates to the detection of vitamin D metabolites. In a particular aspect, the invention relates to methods for detecting derivatized vitamin D metabolites by mass spectrometry. ... | 12/13/2011 |
| 8071392 | Mass spectrometric analysis of proteins using stable isotopes of pyrylium derivates as labels The present invention provides a protein analysis method using a combination of two or more kinds of stable isotopes of a compound represented by the formula (I): wherein R1, R2 and R3 are t... | 12/06/2011 |
| 8053246 | Method of esterifying bio-related molecule for mass spectrometry and method of mass spectrometry of obtained esterified derivative To provide a method for enhancing analysis sensitivity of bio-related molecules in mass spectrometry. To provide a method for rapidly and conveniently analyzing biological acid molecules using the method of enhanced analysis sensitivity in mass spectrometry. ... | 11/08/2011 |
| 8034627 | Methods for detecting dihydroxyvitamin D metabolites by mass spectrometry Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a dihydrorxyvitamin D metabolite in a sample and detecting the amount of the ion to determine the... | 10/11/2011 |
| 8030090 | Method and apparatus for selectively severing and analyzing non-covalent and other bonds of biological macromolecules A biological sample solution is ionized by electrospray and the sample solution is irradiated with an infrared laser beam to dissociate biological macromolecules into the constituents thereof. As a result, only non-covalent bonds of the biological macromolecules can... | 10/04/2011 |
| 8030089 | Method of analyzing differential expression of proteins in proteomes by mass spectrometry A method of identifying molecules of biological origin is disclosed. The molecules are identified and the basis of the accurately determined mass to charge ratio of the molecules and at least a further physico-chemical property such as elution time or charge state. ... | 10/04/2011 |
| 8021892 | System and method for direct digitization of NMR signals A magnetic resonance imaging (MRI) system includes a transmitter that produces an RF excitation pulse that is applied to a subject positioned in the MRI system to induce emission of at least one of an NMR signal and an ESR signal therefrom, and that produces a refer... | 09/20/2011 |
| 8012764 | Mass spectrometer A mass spectrometer and method of mass spectrometry are disclosed wherein two separate samples are mass analysed and then the relative intensity, concentration or expression level of one or more components, molecules or analytes in a first sample is quantitated rela... | 09/06/2011 |
| 7998750 | Mass spectrometry precursor ion selection The present invention is concerned with methods for the selection of precursor ions of a sample polypeptide for fragmentation in mass spectrometry, together with methods for determining at least one putative amino acid sequence for a sample polypeptide, apparatus an... | 08/16/2011 |
| 7985594 | Biradical polarizing agents for dynamic nuclear polarization The present invention provides methods for performing dynamic nuclear polarization using biradicals with a structure of formula (I) as described herein. In general, the methods involve (a) providing a frozen sample in a magnetic field, wherein the frozen sample incl... | 07/26/2011 |
| 7977117 | Vitamin D metabolite determination utilizing mass spectrometry following derivatization The invention relates to the detection of vitamin D metabolites. In a particular aspect, the invention relates to methods for detecting derivatized vitamin D metabolites by mass spectrometry. ... | 07/12/2011 |
| 7972868 | Methods for detecting dihydroxyvitamin D metabolites by mass spectrometry Provided are methods of detecting the presence or amount of a dihydroxyvitamin in D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a dihydroxyvitamin D metabolite in a sample and detecting the amount of the ion to determine t... | 07/05/2011 |
| 7972867 | Methods for detecting vitamin D metabolites by mass spectrometry Provided are methods of detecting the presence or amount of a vitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a vitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount... | 07/05/2011 |
| 7955862 | Method and device for the qualitative and/or quantitative determination of a protein and/or peptide pattern of a fluid sample, which has been taken from a human or animal body Provided are a process and a device for the qualitative and/or quantitative determination of a protein and/or peptide pattern of a liquid sample taken from a human or animal body for checking its state. The peptides and proteins of the liquid sample are processed an... | 06/07/2011 |
| 7951608 | Detecting succinylacetone This invention relates, inter alia, to detecting and/or measuring succinylacetone and one or more additional biological analytes using mass spectrometry. ... | 05/31/2011 |
| 7947511 | Intensified neutral loss tags and use thereof in mass spectrometry Ultrasensitive detection of a chemical substance (analyte) by mass spectrometry is achieved by employing a molecular tag that yields an intense parent ion and then an intense daughter ion in a multi-stage mass spectrometer. ... | 05/24/2011 |
| 7932097 | Method of manufacturing an analytical sample and method of analyzing an analytical sample A method of manufacturing an analytical sample by a secondary ion mass spectrometry method is provided, which comprises a step of forming a separation layer over a substrate, a step of forming one of a thin film and a thin-film stack body to be analyzed over the sep... | 04/26/2011 |
| 7910377 | Methods and apparatuses for preparing a surface to have catalytic activity The invention provides methods and apparatuses that utilize mass spectrometry for preparation of a surface to have catalytic activity through molecular soft-landing of mass selected ions. Mass spectrometry is used to generate combinations of atoms in a particular ge... | 03/22/2011 |
| 7906341 | Methods, mixtures, kits and compositions pertaining to analyte determination This invention pertains to methods, mixtures, kits and compositions pertaining to analyte determination by mass spectrometry using labeling reagents that comprise a nucleophilic reactive group that reacts with a functional group of an analyte to produce a labeled an... | 03/15/2011 |
| 7906342 | Monitoring treatment of cancer patients with drugs targeting EGFR pathway using mass spectrometry of patient samples Methods using mass spectral data analysis and a classification algorithm provide an ability to determine whether a non-small-cell lung cancer patient, head and neck squamous cell carcinoma or colorectal cancer patient has likely developed a non-responsiveness to tre... | 03/15/2011 |
| 7892852 | Method for determining the endogenous antioxidative potential of beverages by means of ESR spectroscopy The present invention relates to a method for determining the endogenous antioxidative potential (EAP) in a beverage sample, preferably beer, wine, juice or mixtures thereof, using ESR spectroscopy. More specifically, the invention relates to a method for measuring ... | 02/22/2011 |
| 7879620 | Method and system for determining whether a drug will be effective on a patient with a disease A process of determining whether a patient with a disease or disorder will be responsive to a drug, used to treat the disease or disorder, including obtaining a test spectrum produced by a mass spectrometer from a serum produced from the patient. The test spectrum m... | 02/01/2011 |
| 7867775 | Selection of head and neck cancer patients for treatment with drugs targeting EGFR pathway Methods using mass spectral data analysis and a classification algorithm provide an ability to determine whether a head and neck squamous cell carcinoma (HNSCC) patient is likely to benefit from a drug targeting an epidermal growth factor receptor pathway, including... | 01/11/2011 |
