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| Number | Title | Issue Date |
| 8163563 | Devices and methods for removing target agents from a sample The invention provides devices, test kits and methods for removing target agents from a sample. The device contains one or more porous matrices having pore sizes larger than 10 μm, and a plurality of particles impregnated therein. The target agents attach the devic... | 04/24/2012 |
| 8119414 | Test strip with slot vent opening Methods of manufacturing test strips are disclosed. Embodiments include laminating a two piece covering layer over a substrate with a series of cavities, wherein the two pieces are separated by a gap, the gap forming a vent opening for the cavities. Other embodiment... | 02/21/2012 |
| 8101425 | Particles embedded in a porous substrate for removing target analyte from a sample The invention provides devices, test kits and methods for removing target agents from a sample. The device contains one or more porous matrices having pore sizes larger than 10 μm, and a plurality of particles impregnated therein. The target agents attach the devic... | 01/24/2012 |
| 7943392 | Discrimination medium, discrimination method, article to be discriminated, and discrimination apparatus A discrimination medium cannot be easily falsified. Since the visibility of the discrimination medium is unique, the discrimination medium is superior in determination of the authenticity. The discrimination medium is structured such that a cholesteric liquid crysta... | 05/17/2011 |
| 7892849 | Reagent stripe for test strip A test strip having a small sample-receiving chamber on the order of less than 1 microliter. The inventive test strip includes a reagent layer that extends across the width of the test strip and also extends to the sample-receiving end, such that the edges of the re... | 02/22/2011 |
| 7879618 | Method and reagent for producing narrow, homogenous reagent strips The present invention concerns a reagent coating mass which can be used in slot-die-coating of flat support materials in the manufacturing processes of test strips. Advantageously, the reagent mass of the invention exhibits certain superior rheological properties su... | 02/01/2011 |
| 7407809 | Method for determining asphaltenes contamination in used marine engine lubricants using UV-visible spectroscopy and chemometrics A method for determining contamination in marine diesel lubricating oils. The method has been found to have particular utility in estimating asphaltenes contamination in marine diesel lubricating oils. The method includes the steps of: (a) obtaining spectral raw dat... | 08/05/2008 |
| 7364914 | Method for diluting a fluid and detecting analytes within a diluted fluid The present invention provides a method and device for processing, sampling, and diluting a fluid and for detecting an analyte within the processed, sampled, and diluted fluid. In the method and device for processing, sampling, and diluting a fluid, an amount of flu... | 04/29/2008 |
| 7354733 | Method for sorting and separating living cells We disclose methods of sorting or separating mixtures of living cells (e.g., eukaryotic, prokaryotic, mammalian, pathogenic, bacterial, viral, etc.). We perform our methods by activating cell-selective photophoric labels, which photosensitize and chemically reduce a... | 04/08/2008 |
| 7347971 | Spreading layers and their use in test strips A spreading material is described which comprises a porous flat-shaped structure impregnated with a wetting agent, wherein the wetting agent is N-oleoyl-sarcosinate. ... | 03/25/2008 |
| 7319038 | Sensor for monitoring an analyte A food spoilage sensor of the general formula wherein M is a transition metal ion; D1, D2, D3 and D4 can be the same or different and can be N or P; R1 and R... | 01/15/2008 |
| 7314453 | Handheld diagnostic device with renewable biosensor A handheld diagnostic device having a test head and a handle is equipped with an open test channel having sensors and liquid reagent dispensing opening for the diagnostic testing of body fluids. The test channel can draw in fluid sample by capillary force and be clo... | 01/01/2008 |
| 7300750 | Analyte assay device with preabsorbing zone The present invention provides an assay device for detection of an analyte which is a member of a specific binding partner in a sample, the assay device comprising a sample application zone, a preabsorbing zone and a specific binding zone. The device can provide a H... | 11/27/2007 |
| 7300802 | Membrane strip biosensor system for point-of-care testing The present invention relates to a biosensor for point-of-care testing (POCT) whose detection sensitivity was remarkably improved by introducing to membrane strip chromatographic assay system a successive cross-flow procedure for immune reaction and enzymatic reacti... | 11/27/2007 |
| 7300633 | Specimen collection container The present invention recognizes that sample handling devices, particularly those used for testing for substances of abuse, do not allow for a separation of the bulk sample from a sample thereof to be tested. The present invention provides such a device and methods ... | 11/27/2007 |
| 7287318 | Biosensor A biosensor is provided that comprises a plate element with a pre-determined reaction zone and a recess positioned adjacent to the reaction zone. The biosensor also comprises a reagent that is positioned on the reaction zone. In preferred embodiments, the recess cir... | 10/30/2007 |
| 7288174 | Electrochemical biosensor There is provided the reagent layer composition that can substantially reduce the measurement bias arising from hematocrits. The addition of fatty acid (4-20 carbons) and quaternary ammonium salt to a commonly used reagent layer composition composed of an enzyme, an... | 10/30/2007 |
| 7270959 | Specimen collection container The present invention recognizes that sample handling devices, particularly those used for testing for substances of abuse, do not allow for a separation of the bulk sample from a sample thereof to be tested. The present invention provides such a device and methods ... | 09/18/2007 |
| 7241621 | Method for determining residual fuel and insolubles contamination in used marine engine lubricants using UV-visible spectroscopy and chemometrics A method for determining contamination in marine diesel lubricating oils. The method has been found to have particular utility in estimating residual fuel and insolubles contamination in marine diesel lubricating oils. The method includes the steps of: (a) obtaining... | 07/10/2007 |
| 7238534 | Capillary active test element having an intermediate layer situated between the support and the covering The invention concerns a device for withdrawing samples of liquid samples for analytical elements. The capillary-device channel is essentially formed by a carrier, a cover and optionally an intermediate layer between the cover and carrier. A notch is located in one ... | 07/03/2007 |
| 7226793 | Method for adding an apparent non-signal line to a lateral flow assay A test device and method for determining the presence or absence of an analyte in a fluid sample, the test device including a support bearing a mark thereon, and a matrix defining an axial flow path. In operation, an observation area in the test device becomes trans... | 06/05/2007 |
| RE39664 | Lateral flow chromatographic binding assay device The present invention relates to improved specific binding assay devices comprising a chromatographic medium including a reaction site at which a specific binding reagent is immobilized, a sample application well located adjacent to the chromatographic medium and of... | 05/29/2007 |
| 7195921 | Adhered membranes retaining porosity and biological activity An assay pad for measuring the concentration of HDL-associated cholesterol in a sample, a method for using the pad, and a diagnostic assay device for carrying out the method are described. The assay pad includes a polymer adhesive or heat laminate bond. The assay de... | 03/27/2007 |
| 7195923 | Ratiometric determination of glycated protein The present invention provides methods for determining a ratio of an amount of a glycated form of a protein to a total amount of the protein in a sample containing the glycated protein, the glycosylated protein, or the glycoprotein. The method incorporates lateral f... | 03/27/2007 |
| 7192555 | Device for collection and assay of oral fluids A device for collecting and transporting aqueous fluid from the oral cavity to a lateral chromatographic strip for test is disclosed. The lateral chromatographic strip is placed within and extend along a cavity defined in a housing. At least one inspection site to t... | 03/20/2007 |
| 7192729 | Methods for assaying homocysteine The present invention relates to compositions and methods for assaying homocysteine (Hcy) and thus related moieties, e.g., S-adenosylhomocysteine (SAH) or adenosine. More particularly, assay methods that employ, mutant SAH hydrolase having binding affinity for Hcy, ... | 03/20/2007 |
| 7189576 | Method for measuring substance and testing piece A method of measuring an analyte, comprising a step of measuring a detectable substance by using a reaction system including a formation reaction of the detectable substance based on a chemical reaction of the analyte contained in a sample, wherein a layered inorgan... | 03/13/2007 |
| 7184894 | Quantitative measurement method and quantitative measurement chip for target substance The present invention provides a quantitative measurement method and quantitative measurement chip which can perform quantitative measurement of a target substance in a short period of time. The invention provides a quantitative measurement method in which a three d... | 02/27/2007 |
| 7179657 | Method for adding an apparent non-signal line to a rapid diagnostic assay A test device and method for determining the presence or absence of one or more analytes in a fluid sample, the test device including a support or member bearing a mark thereon, and a matrix or member containing a capture zone. In operation, an observation area in t... | 02/20/2007 |
| 7138280 | Masking of the background fluorescence and luminescence in the optical analysis of biomedical assays In a process for the quantitative optical analysis of biological cells labelled with a fluorescent dye, the sensitivity of analytical detection can be considerably improved if a masking dye, which absorbs the excitation light for the fluorescent dye and/or its emiss... | 11/21/2006 |
| 7125711 | Method and apparatus for splitting of specimens into multiple channels of a microfluidic device A microliter liquid sample, particularly a biological sample, is analyzed in a device employing centrifugal and capillary forces. The sample is moved by capillary forces into one or more metering wells which define the amount of the sample to be analyzed in subseque... | 10/24/2006 |
| 7125493 | Highly asymmetric, hydrophilic, microfiltration membranes having large pore diameters The present invention relates to the field of synthetic polymeric microfiltration membrane materials that are fabricated to separate liquids from solids contained therein. One aspect of the invention relates to a highly asymmetric, hydrophilic microfiltration membra... | 10/24/2006 |
| 7115421 | Method and device for measurement of hematocrit Hematocrit in a blood sample is visualized by separating blood plasma from red blood cells in the blood sample on an absorbent substrate provided with a blood plasma soluble dye. Methods and devices to achieve the visualization are described. ... | 10/03/2006 |
| 7115362 | Electrochemical test device and related methods An electrochemical test device is provided for determining the presence or concentration of an analyte in an aqueous fluid sample. The electrochemical test device includes a working electrode and a counter electrode made of an amorphous semiconductor material. The w... | 10/03/2006 |
| 7094354 | Method and apparatus for separation of particles in a microfluidic device A microfluidic device provides separation of particles in a liquid sample, particularly, separation of a sample of whole blood into its components for further analysis. Separation into red blood cells and plasma occurs within a few seconds after the blood sample has... | 08/22/2006 |
| 7070939 | Methods for detecting vasculopathies and tumors This invention relates generally to the field of prognosis and diagnosis of vasculopathy and certain tumors. In particular, the invention provides a method for prognosing or diagnosing vasculopathy, neuroectodermal tumor, epithelial tumor, myelomonocytic tumor or ly... | 07/04/2006 |
| 7064837 | Measuring sensor utilizing attenuated total reflection and measuring chip assembly Disclosed herein is a sensor utilizing attenuated total reflection. The sensor is constructed of a measuring chip, an optical system, and a measuring section. The measuring chip is equipped with a dielectric block, a thin film layer formed on the dielectric block, a... | 06/20/2006 |
| 7063952 | Masking background flourescence and luminescence in optical analysis of biomedical assays In a process for the quantitative optical analysis of fluorescently labelled biological cells 5, a cell layer on a transparent support at the bottom 2 of a reaction vessel 1 is in contact with a solution 3 containing the fluorescent dye | 06/20/2006 |
| 7049130 | Diagnostic sanitary test strip An improved multi-layered diagnostic sanitary test strip for receiving a heterogenous fluid, such as whole blood, to test for presence and/or amount of a suspected analyte in the fluid by facilitating a color change in the strip corresponding to the amount of the an... | 05/23/2006 |
| 7045342 | Diagnostic detection device and method The invention provides an improved test cell for detecting the presence of an analyte in a liquid sample. The device has an elongate casing defining a liquid sample inlet, a reservoir volume, a test volume, and a window through the casing at the test volume. Dispose... | 05/16/2006 |
