Did You Know...
...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
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| Number | Title | Issue Date |
| 8187892 | Co-topo-polymeric compositions, devices and systems for controlling threshold and delay activation sensitivities Co-topo-polymeric indicator compositions and methods for making and using the same are provided. Indicator compositions of the invention include a polymer and undergo a color change, which may be reversible or irreversible, in response to an applied stimulus, e.g., ... | 05/29/2012 |
| 8168439 | Method for measuring an analyte in blood An electrochemical immunosensor system with reduced interference, comprising: a first immunosensor that generates an electrochemical signal based on the formation of a sandwich between an immobilized antibody, a target analyte and a labeled antibody, wherein a porti... | 05/01/2012 |
| 8163562 | Photon reducing agents for fluorescence assays The present invention provides a method for reducing undesirable light emission from a sample using at least one photon producing agent and at least one photon reducing agent (e.g. dye-based photon reducing agents). The present invention further provides a method fo... | 04/24/2012 |
| 8153440 | Methods for altering surface characteristics of microspheres Various methods for altering surface characteristics of a microsphere are provided. One method includes coupling an enolic acid to the microsphere to modify the surface characteristics of the microsphere. The surface characteristics may include charge density and/or... | 04/10/2012 |
| 8039267 | Detection method, detection apparatus, and sample cell and kit for detection A sensor-chip includes a sensor-portion having at least a metal-layer deposited on a surface of a dielectric-plate. A fluorescent-label binding-substance in an amount corresponding to the amount of a detection-target-substance in a liquid-sample binds onto the senso... | 10/18/2011 |
| 8034626 | Labels, their production process and their uses The present invention relates to labels capable of forming a covalent or non-covalent bond with a target molecule, consisting of a dye to which there is bonded in a covalent manner by one or more carbons of its chemical structure: ... | 10/11/2011 |
| 7972866 | Biosensor and ultrasonic method of making a biosensor There is provided a test strip for testing a fluid sample, including a sample cavity configured to receive the fluid sample and an ultrasonically-spread reagent layer arranged on at least one surface of the sample cavity. There is also provided a method for making a... | 07/05/2011 |
| 7960181 | Chromoionophore and method of determining potassium ions The invention relates to methods of determining potassium ions in a sample, wherein the ions are contacted with a compound having chromophoric moiety and an ionophoric moiety, where the ionophoric moiety interacts with the potassium ions present in the sample, resul... | 06/14/2011 |
| 7932096 | Trioxyethylene gold nanoclusters functionalized with a single DNA A method of making a nanoclusters functionalized with a single DNA strand comprising the steps of providing nanoclusters, combining said nanoclusters with thiolated DNA, incubating said nanoclusters and thiolated DNA mixture, combining said mixture with a solution c... | 04/26/2011 |
| 7867774 | Methods for altering surface characteristics of microspheres Various methods for altering surface characteristics of a microsphere are provided. One method includes coupling an enolic acid to the microsphere to modify the surface characteristics of the microsphere. The surface characteristics may include charge density and/or... | 01/11/2011 |
| 7858383 | Chromoionophore and method of determining sodium ions The invention relates to methods of determining sodium ions in a sample, wherein the ions are contacted with a compound having chromophoric moiety and an ionophoric moiety, where the ionophoric moiety interacts with the sodium ions present in the sample, resulting i... | 12/28/2010 |
| 7842511 | Colorimetric monitoring of reactions in solution and solid phase automated and manual systems The present invention relates to the a new protecting group, 4-(O-nitrophthalimido)butyric acid (NPB) that may be attached to a monomer unit during oligosaccharide synthesis such that upon cleavage of this molecule, the solution turns orange. The orange color allows... | 11/30/2010 |
| 7785894 | Package for enclosing food An indicator that reacts with at least one gaseous compound in such a way that the color of the indicator is changed. The indicator is a layer formed on a substrate and including metallic silver and/or metallic copper. ... | 08/31/2010 |
| 7704750 | Visual spill indicator Composition, which includes a dye that changes color when contacted with a suitable amount of an organic substance, in conjunction with a matrix, paste, support or web, can indicate visually or photometrically the presence of the organic substance. An organic spill ... | 04/27/2010 |
| 7662639 | Composition, kit and method of detecting and locating traces of blood The invention relates to a composition for the detection of traces of human or animal blood. The aforementioned composition comprises a luminol compound, an oxidizing agent and a base which are diluted in a preferably aqueous solvent. Said composition is characteriz... | 02/16/2010 |
| 7655474 | Trioxyethylene gold nanoclusters functionalized with a single DNA A method of making a nanoclusters functionalized with a single DNA strand comprising the steps of providing nanoclusters, combining said nanoclusters with thiolated DNA, incubating said nanoclusters and thiolated DNA mixture, combining said mixture with a solution c... | 02/02/2010 |
| 7651864 | Coating solution for glucose sensing membrane and method of manufacturing optical glucose sensor chip A method of preparing a coating solution for a glucose sensing membrane, the method comprising preserving a first solution containing an oxidizing enzyme or a reducing enzyme of glucose and a reagent for generating a substance for coloring a coloring agent dissolved... | 01/26/2010 |
| 7635596 | Method for monitoring degradation of lubricating oils A method for monitoring degradation of lubricating oils. The method comprises steps of: (a) adding to a lubricating oil at least one compound having formula (I) wherein R1 and R2 independently are hydr... | 12/22/2009 |
| 7615377 | Fluorescein-based metal sensors The present invention is directed, in part, to fluorescein-based ligands for detection of metal ions, and methods of making and using the same. ... | 11/10/2009 |
| 7608461 | Surface engineered nanoparticles for improved surface enhanced Raman scattering applications and method for preparing same A method for producing metal nanoparticles that when associated with an analyte material will generate an amplified SERS spectrum when the analyte material is illuminated by a light source and a spectrum is recorded. The method for preparing the metal nanoparticles ... | 10/27/2009 |
| 7563621 | Absorbing organic reagents into diagnostic test devices by formation of amine salt complexes A method of applying an organic acid reagent having limited transolubility in organic solvents, aqueous solvents, and mixtures thereof to a component of a diagnostic test device by mixing an organic acid reagent and an amine to form a salt complex, dissolving the sa... | 07/21/2009 |
| 7439079 | Assay devices having detection capabilities within the hook effect region A lateral flow assay device for detecting the presence or quantity of an analyte within a test sample is provided. The device utilizes multiple zones, one of which serves as an indicator of whether or not the analyte in the test sample is within the “hook effectâ€... | 10/21/2008 |
| 7435981 | Electron beam sterilizer A plurality of vessel holder means 14 are mounted around a revolving body 12 at an equal circumferential spacing. Each vessel holder means 14 includes two holders 26, 26 for carrying two vessels 4, 4 in vertical alignment. A path a... | 10/14/2008 |
| 7432105 | Self-calibration system for a magnetic binding assay A self-calibrated, magnetic binding assay (e.g., sandwich, competitive, etc.) for detecting the presence or quantity of an analyte residing in a test sample is provided. The magnetic binding assay includes detection probes capable of generating a detection signal (e... | 10/07/2008 |
| 7427504 | Determining fluid chemistry of formation fluid by downhole reagent injection spectral analysis A method for analyzing formation fluid in earth formation surrounding a borehole includes storing analytical reagent in a reagent container in a fluids analyzer in a formation tester and moving the formation tester, including the reagent, downhole. Reagent from the ... | 09/23/2008 |
| 7416891 | Reagent and method for classifying leucocytes A reagent for classifying leucocytes, including: a) at least one of surfactant selected from a cationic surfactant, an amphoteric surfactant, and the combination thereof; b) an organic compound having phenyl or heterocyclic group, wherein when the surfactant is a ca... | 08/26/2008 |
| 7416703 | Polymer based lanthanide luminescent sensors for the detection of organophosphorus compounds A device for measuring and detecting the organophosphonis compounds, such as a pesticides or a nerve agents is provided. The devices function by selectively binding an organophosphorous compound to a luminescent functionality-imprinted copolymer. The copolymers poss... | 08/26/2008 |
| 7413905 | Reagents and methods for classifying leukocytes The present invention relates to a reagent for classifying leukocytes including (a) at least one surfactant capable of lysing erythrocytes and partly damaging the cell membrane of leukocytes, (b) at least one organic compound bearing an anionic group capable of bind... | 08/19/2008 |
| 7407626 | Composition and method of use of medical test kit A medical test kit includes a glucose testing composition, a protein testing composition, a bilirubin testing composition, a bilinogen testing composition, an amylase testing composition, a blood testing composition, a calcium testing composition, a nitrite testing ... | 08/05/2008 |
| 7399639 | Sensors, and methods of making and using the same The present invention is directed, in part, to sensors for detecting metal ions, and methods of making and using the same. ... | 07/15/2008 |
| 7387880 | Method for monitoring resting and activated platelets in unfixed blood samples The amount of platelet surface proteins in a sample may be measured by collecting a sample containing platelets into a collection tube containing a platelet stabilizing composition, labeling the platelet surface protein and detecting by cytometry. ... | 06/17/2008 |
| 7381564 | Method of calibrating the zero point of an apparatus used to determine a quantity of silica using a colorimetric method A method of calibrating the zero point of an apparatus which is used to determine the quantity of silica contained in a silica solution sample to be analysed, using a colorometric method. The colorometric method used by the apparatus consists of successively introdu... | 06/03/2008 |
| 7378281 | Process to measure PPB levels of dissolved copper in jet fuels and other non-aqueous fluids using a colorimetric process A method of measuring the concentration of metal ions in a sample comprising the steps of: providing a sample comprising a nonpolar, liquid hydrocarbon, suspected of containing a metal ion; adding a dye such as a spirobenzopyran dye or bathocuproine and a reducing a... | 05/27/2008 |
| 7374946 | Method for the detection of compounds comprising methylenedioxyphenyl Process and a test kit for the detection of drugs of methylenedioxy amphetamine family and derivatives, are disclosed. The process comprises (a) sampling sufficient amount of a material, suspected to be examined comprise of said methylenedioxyphenyl group; (b) admix... | 05/20/2008 |
| 7371247 | Method and apparatus for penetrating tissue A tissue penetrating system includes a plurality of penetrating members each having a tip. A penetrating member driver is coupled to the plurality of penetrating members. Each tip of a penetrating member is uncovered during launch of the penetrating member by the pe... | 05/13/2008 |
| 7371511 | Polydiacetylene polymer blends Polymer blend compositions that include diacetylene segments are provided. The polymers containing diacetylene segments are capable of a calorimetric indication in response to stimuli, such as heat, an analyte or exposure to certain environmental factors, despite be... | 05/13/2008 |
| 7364918 | Colorimetric sensors constructed of diacetylene materials Colorimetric sensors comprising a receptor incorporated within polydiacetylene assemblies to form a transducer capable of indicating a color change when contacted with an analyte are disclosed. Methods of using the colorimetric sensor and a kit for the colorimetric ... | 04/29/2008 |
| 7361410 | External modification of composite organic inorganic nanoclusters comprising raman active organic compound Modified and functionalized metallic nanoclusters capable of providing an enhanced Raman signal from an organic Raman-active molecule incorporated therein are provided. For example, modifications include coatings and layers, such as adsorption layers, metal coatings... | 04/22/2008 |
| 7361479 | Assay The present invention provides a method of determining the presence or amount of newly synthesized antibody in a sample in response to an immunogen by detecting the released antibodies or parts thereof in a sample containing lymphocytes which have been disrupted whe... | 04/22/2008 |
| 7361314 | Microfluid reaction carrier having three flow levels and a transparent protective layer The present invention relates to a microfluid reaction carrier intended for the purely fluid or light-controlled synthesis or analysis of oligomers or polymers. The reaction carrier comprises a structure of flow channels for the fluids, while supply channels and dis... | 04/22/2008 |
