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| Number | Title | Issue Date |
| 8088628 | Stimulated and coherent anti-stokes raman spectroscopic methods for the detection of molecules Spectroscopic analysis systems and methods for analyzing samples are disclosed which exploit inelastically scattering radiation to amplify optical signals from an irradiated sample. Samples are irradiated in a chamber having a resonant cavity containing a plurality ... | 01/03/2012 |
| 8084267 | Corrosion simulator and corresponding method A laboratory degradation test system for testing degradation of a test specimen in a test fluid flow includes a reactor assembly, which reactor assembly comprises: a reactor vessel, the reactor vessel having a reaction space, an inlet and an outlet and a specimen ho... | 12/27/2011 |
| 8062901 | Devices and methods for sample collection and analysis The present invention provides devices, methods, and kits for the collection of a solid or semi-solid sample and analysis for the presence, absence, or quantity of an analyte. The invention provides a collection slide having a first card and a second card. The first... | 11/22/2011 |
| 8012429 | Simplified analyzer There is provided a simplified analyzer including a see-through hermetic container having powdery or granular color reaction reagent, and a tap member partially inserted in the hermetic container in an extractable state. The tap member is provided at one end with a ... | 09/06/2011 |
| 8003061 | Test strip card The present invention relates to a test strip for determining and/or quantifying a property of a sample, such as the concentration of an analyte, the pH, the viscosity, or the specific gravity of a fluid specimen. More particularly, the present invention relates to ... | 08/23/2011 |
| 7981387 | Immunoassay device with improved sample closure An apparatus and method for sealing a fluid sample collection device, comprising loading a fluid sample collection device with a fluid sample, said device comprising a housing having at least one substantially planar surface that includes an orifice in fluid communi... | 07/19/2011 |
| 7964413 | Method for continuous mode processing of multiple reaction receptacles in a real-time amplification assay An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations in which discrete aspects of the assay are performed on fluid samples contained in sample vessels. The analyzer includes stations for automatically preparing a ... | 06/21/2011 |
| 7888129 | Surface-enhanced spectroscopic method, flexible structured substrate, and method of making the same A method of obtaining a surface-enhanced optical property of an analyte using a flexible structured substrate having a metal layer conformably disposed on nanostructure, a flexible structured substrate, and a method of making the same. ... | 02/15/2011 |
| 7867773 | Method of holding a slide cassette for fluidic injection A system for holding a slide. The system includes a housing having a side wall and a top. The top includes a recess surrounded by an outer rim. The system also includes an inlet port in communication with the recess and an elevating mechanism capable of receiving th... | 01/11/2011 |
| 7863053 | Swab-based diagnostic systems A diagnostic test system for detecting the presence or absence of an analyte within a test sample is provided. For instance, the system may include a swab and a detection unit. The detection unit includes a first component that is capable of receiving the swab, the ... | 01/04/2011 |
| 7799575 | Flow cytometers A calibration method for a flow cytometer with a multichannel detector module. During calibration, the fluorescence intensity data values for the different detector channels are used to calculate normalization factors needed to adjust subsequent data collected by ea... | 09/21/2010 |
| 7790469 | Micro structure for sensing trace chemicals A method to fabricate an optical scattering probe and the method includes the steps of a) depositing an conductive layer on a substrate followed by depositing a noble metal layer on top of the conductive layer and then an aluminum layer on top the noble metal layer;... | 09/07/2010 |
| 7790468 | Test object receptacle, test apparatus, and test method A test object receptacle, capable of measuring a test object in a wide range of concentrations with good accuracy and within a short time, contains a plurality of fine protruding portions inside grooves. The test object receptacle can fix antigens, antibodies and te... | 09/07/2010 |
| 7776609 | Reference microplates and methods for making and using the reference microplates A reference microplate is described herein which can be used to help calibrate and troubleshoot an optical interrogation system. In one embodiment, the reference microplate has a frame with an array of wells each of which contains an optical biosensor and each optic... | 08/17/2010 |
| 7727772 | Fluid contamination analyzer and a sample cell therefor A fluid contamination analyzer has a sample cell containing a trapping medium capable of trapping contaminants suspended in the aqueous fluid flowing through the trapping medium, a light source for illuminating the trapping medium to cause the entrapped contaminants... | 06/01/2010 |
| 7682833 | Immunoassay device with improved sample closure An apparatus and method for sealing a fluid sample collection device, comprising: loading a fluid sample collection device with a fluid sample, said device comprising a housing having at least one substantially planar surface that ... | 03/23/2010 |
| 7651863 | Surface-enhanced spectroscopic method, flexible structured substrate, and method of making the same A method of obtaining a surface-enhanced optical property of an analyte using a flexible structured substrate having a metal layer conformably disposed on nanostructure, a flexible structured substrate, and a method of making the same. ... | 01/26/2010 |
| 7629175 | Test element with a one layer reaction film The invention concerns test elements and methods for the optical detection of an analyte in a sample. The test element includes a support having at least one transparent portion, and a one-layer film positioned on the support. The film has a thickness when dry of le... | 12/08/2009 |
| 7625760 | Analyzing cartridge and liquid feed control device An analyzing cartridge and method for using it to analyze a sample having a plurality of reservoirs and capillaries connected for communication between these reservoirs and is provided therein with a reagent required for analysis. The reservoirs are provided with op... | 12/01/2009 |
| 7604999 | System and method for universal identification of biological samples A system and method for identifying a biological sample associated with a container is disclosed. A universally unique identifier is associated with each container. In one or more embodiments, the identifier comprises one or more markings having a specular reflectan... | 10/20/2009 |
| 7582487 | Method and device for laminar flow on a sensing surface Methods and devices are provided for controlling a fluid flow over a sensing surface within a flow cell. The methods employ laminar flow techniques to position a fluid flow over one or more discrete sensing areas on the sensing surface of the flow cell. Such methods... | 09/01/2009 |
| 7575934 | Oriented magnetic particle-fluorescence detectable moiety compositions and methods of making and using the same Compositions and methods relating to magnetic particles comprising one or more fluorescence detectable moieties positioned asymmetrically with respect to the magnetic pole regions of the particles are described. The compositions are useful for detecting analytes. | 08/18/2009 |
| 7556968 | Scanning probe microscope and molecular structure change observation method A scanning probe microscope includes a cantilever, a scanning mechanism which relatively scans the cantilever and a sample which exist in liquid, and an application mechanism which applies photolytic light to a caged compound existing in the liquid or the sample. | 07/07/2009 |
| 7547554 | Method and device for the detection of very small quantities of particles The invention relates to a method and a device for detecting very small quantities of particles. The inventive method is based on a detection of antigen-antibody reaction products and provides a very high detection sensitivity all the way to the femtomolar or attomo... | 06/16/2009 |
| 7517694 | Metering tip with internal features to control fluid meniscus and oscillation A metering tip for use in a clinical analytical apparatus includes a tapered body having at least one interior stepped areas. Each of the stepped areas include a sharp diametrical edge for latching a fluid meniscus being dispensed from the tip and for reducing fluid... | 04/14/2009 |
| 7504264 | Method for characterizing a highly parallelized liquid handling technique using microplates and test kit for carrying out the method A method for characterizing highly parallelized liquid handling technology using microplates and test kit for carrying out the method. Possibilities for characterizing a multi-channel or many-channel handling technology are known in principle. However, especially wi... | 03/17/2009 |
| 7439079 | Assay devices having detection capabilities within the hook effect region A lateral flow assay device for detecting the presence or quantity of an analyte within a test sample is provided. The device utilizes multiple zones, one of which serves as an indicator of whether or not the analyte in the test sample is within the “hook effectâ€... | 10/21/2008 |
| 7435601 | Biological specimen handling method An apparatus for collecting, transporting and storing biological specimens. The apparatus includes a base having a tray portion for receiving the biological specimen and a lid operably connected to the base and moveable with respect to the base between a first close... | 10/14/2008 |
| 7432105 | Self-calibration system for a magnetic binding assay A self-calibrated, magnetic binding assay (e.g., sandwich, competitive, etc.) for detecting the presence or quantity of an analyte residing in a test sample is provided. The magnetic binding assay includes detection probes capable of generating a detection signal (e... | 10/07/2008 |
| 7427504 | Determining fluid chemistry of formation fluid by downhole reagent injection spectral analysis A method for analyzing formation fluid in earth formation surrounding a borehole includes storing analytical reagent in a reagent container in a fluids analyzer in a formation tester and moving the formation tester, including the reagent, downhole. Reagent from the ... | 09/23/2008 |
| 7425453 | Integrated circuit porphyrin-based optical Fabry-Perot chemical sensor A Fabry-Perot cavity has a pair of partially transmissive, partially reflective, surfaces. A first of the surfaces is flexibly suspended adjacent and parallel to a second of the surfaces. A gap exists between the surfaces. A variable electrostatic potential permits ... | 09/16/2008 |
| 7410612 | Gunpowder particle test kit A gunpowder particle test kit for determining gunpowder residue includes a transparent sleeve having a closed end and an open folded end sealed with a clip forming a sealed cavity carrying a test strip and a crushable ampoule carrying a diphenylamine solution. The t... | 08/12/2008 |
| 7410805 | Aerosol detection system using optical and mass discrimination A system to detect and identify various aerosol agents, such as biological agents which have been aerosolized, is disclosed. The system generally includes a mechanism to collect a selected sample of atmosphere which may include the aerosol agent, a sub-system to det... | 08/12/2008 |
| 7402441 | Method of detecting an analyte in a fluid A method for the detection of an analyte in a fluid, comprising contacting the fluid with a holographic element comprising a medium and a hologram disposed throughout the volume of the medium, wherein an optical characteristic of the element changes as a result of a... | 07/22/2008 |
| 7396676 | Evanescent wave sensor with attached ligand The invention in particular embodiments provides an evanescent wave sensor which includes a ligand bound to a sensor substrate via a NCYX linker moiety, as defined herein. Methods of making the subject evanescent wave sensors are also provided which include contacti... | 07/08/2008 |
| 7393690 | Systems and methods for measuring fluid properties A method for measuring properties of a fluid including placing a quantity of fluid in a container; inducing flow in the fluid wherein the flow is substantially streamlined in at least a measuring region of the container by constricting flow, and wherein the fluid is... | 07/01/2008 |
| 7390669 | Simultaneous and rapid determination of multiple component concentrations in a Kraft liquor process stream The present invention is a rapid method of determining the concentration of the major components in a chemical stream. The present invention is also a simple, low cost, device of determining the in-situ concentration of the major components in a chemical stream. In ... | 06/24/2008 |
| 7387898 | Apparatus and method for conducting assays A multi-well assay plate structure (54) and assay apparatus and a method for performing chemical biochemical assays is described. The multi-well assay plate structure (54) defines a relatively shallow substantially enclosed space (71) above a pl... | 06/17/2008 |
| 7387899 | Saliva sample collection system Test kit whereby the sponge portion of kit is used to swab saliva. The saliva is then extracted from sponge by either squeezing it out or through the use of a centrifuge. The sponge portion of the kit is attached to a collection container when used in the centrifuge... | 06/17/2008 |
| 7384598 | Diagnostic device Diagnostic devices for detecting the presence of an analyte in a sample are provided. Devices of the present invention comprise a means for inducing a pressure differential on a sample to direct the sample to a test surface. In one embodiment, the means for inducing... | 06/10/2008 |
