...that after Parker Brothers executives turned down the game of Monopoly because it had "52 fundamental errors" (including taking too long to play), a copy of the game wound up in the home of the company president who stayed up until 1 a.m. to finish playing it? He was so impressed by the game that the next day he wrote to inventor Charles Darrow and offered to buy it!
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| Number | Title | Issue Date |
| 7745227 | System for analysis of explosives A system for analysis of explosives. Samples are spotted on a thin layer chromatography plate. Multi-component explosives standards are spotted on the thin layer chromatography plate. The thin layer chromatography plate is dipped in a solvent mixture and chromatogra... | 06/29/2010 |
| 7333195 | Method for detecting photosynthesis inhibition This invention relates to a method for detecting the photosynthesis-inhibitory activity of substances by providing cells or cell parts with an intact photosystem, introducing the cells or cell parts into a planar layer, applying the test substance to the planar laye... | 02/19/2008 |
| 7303925 | Method of detecting an analyte for lateral flow immunoassay tests A visual perception of a colored site in an immunoassay device comprising a strip for enabling capillary migration of a fluid sample therealong, a labeled reagent disposed on the strip and formulated for suspension in the sample migrating therepast and a captive rea... | 12/04/2007 |
| 7278291 | Trace gas sensor with reduced degradation The degradation over time that is commonly seen with analyte-binding proteins when used as sensors for trace amounts of an analyte in a gaseous mixture is reduced by maintaining the sensor in a low-oxygen or oxygen-free environment. ... | 10/09/2007 |
| RE39664 | Lateral flow chromatographic binding assay device The present invention relates to improved specific binding assay devices comprising a chromatographic medium including a reaction site at which a specific binding reagent is immobilized, a sample application well located adjacent to the chromatographic medium and of... | 05/29/2007 |
| 7195923 | Ratiometric determination of glycated protein The present invention provides methods for determining a ratio of an amount of a glycated form of a protein to a total amount of the protein in a sample containing the glycated protein, the glycosylated protein, or the glycoprotein. The method incorporates lateral f... | 03/27/2007 |
| 7192721 | Universal rapid test and method for detection of tuberculosis in multiple host species A universal test apparatus for detecting tuberculosis (TB) in any of many different species of non-primate mammals is provided. The universal test apparatus includes a test site having a mycobacterial antigen cocktail comprising ESAT-6/CFP10 and 16 kDa/MPB83 polyfus... | 03/20/2007 |
| 7192555 | Device for collection and assay of oral fluids A device for collecting and transporting aqueous fluid from the oral cavity to a lateral chromatographic strip for test is disclosed. The lateral chromatographic strip is placed within and extend along a cavity defined in a housing. At least one inspection site to t... | 03/20/2007 |
| 7166437 | Measurement of elastic fiber breakdown products in sputum The subject invention is directed to the measurement of elastic fiber breakdown products in human sputum obtained from patients with emphysema and other lung diseases. Measurement of elastic fiber breakdown products may be used to monitor the progression of lung dis... | 01/23/2007 |
| 7160731 | Examination method of buffer capacity of saliva and examination instrument of buffer capacity of saliva To provide a simple examination method of buffer capacity of saliva without influence by examiner's subjectivity and an examination instrument to carry out suitably the examination method, an examination instrument, in which two to ten kinds of chemical liquids each... | 01/09/2007 |
| 7141160 | Chiral columns with broad chiral selectivity A general chiral column with a multipleproline-based chiral stationary phase. Embodiments include chiral stationary phases of the following formula: wherein n is any integer of 2 or greater, and analogs and isome... | 11/28/2006 |
| 7132296 | Method for assaying the antioxidant capacity of a sample A method of assaying the antioxidant capacity of a sample, the method including preparing an extraction solution including a solubility enhancing compound, adding the sample to the extraction solution, extracting the antioxidants present in the sample, adding a fluo... | 11/07/2006 |
| 7112453 | Retentate chromatography and protein chip arrays with applications in biology and medicine This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity conditions, and detecting the analytes retained on the substrate by d... | 09/26/2006 |
| 7045098 | Apparatus and method for removing interfering substances from a urine sample using a chemical oxidant Urine samples are made free of potentially interfering substances, such as alkaloids or pharmaceuticals, by contacting the urine sample with an amount of a chemical oxidizing agent in a disposable oxidation bag, while retaining the physical indicia characteristic of... | 05/16/2006 |
| 6929955 | Interactive system for presenting and eliminating substances The present invention relates to an interactive system comprising at least one active surface of plastic from monomers containing at least one structural element derived from a carbon dioxide (A), and at least one substance associated to a linker with at least one s... | 08/16/2005 |
| 6902889 | Analytical method and advice The invention relates to an analytical chromatographic method which comprises the steps of: a) providing a membrane type flow matrix attached to a liquid-impervious backing, which flow matrix permits a capillary force assisted late... | 06/07/2005 |
| 6881586 | Retentate chromatography and protein chip arrays with applications in biology and medicine This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity conditions, and detecting the analytes retained on the substrate by d... | 04/19/2005 |
| 6858434 | Method for synthesis, separation and screening of a plurality of compounds in the same bulk of a stationary phase A method for sequentially performing a synthesis, separation and screening of chemical entities, especially a combinatorial library, is described. The method utilises a bulk of a stationary phase (e.g. silica gel, aluminium oxide, cellulose, etc. for example arrange... | 02/22/2005 |
| 6852541 | Rapid assay for testing overall oxidative stress The invention relates to an assay for testing oxidative stress of a subject by measurement of oxidants in biological fluids such as urine, plasma, bioreactor medium and respiratory aspirants. There is provided a method of determining oxidative stress in a mammalian ... | 02/08/2005 |
| 6830933 | Reference standards for determining the purity or stability of amlodipine maleate and processes therefor Amlodipine aspartate and amlodipine maleamide are used as reference standards or markers in determining the purity of amlodipine maleate substances and products. ... | 12/14/2004 |
| 6811969 | Retentate chromatography—profiling with biospecific interaction adsorbents This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity conditions, and detecting the analytes retained on the substrate by d... | 11/02/2004 |
| 6790652 | Method and apparatus for high density format screening for bioactive molecules A method and apparatus for screening an array of test compounds for bioactivity by contacting an array of test compounds with a detector layer capable of detecting bioactivity, and detecting a detector layer response. The detector layer is comprised of physiological... | 09/14/2004 |
| 6787366 | Microspot test kit and method for chemical testing A method, system and kit for detecting the presence of an analyte includes placing a solution containing the analyte in a microcapillary tube and placing the microcapillary tube in contact with a layer of sorbent material so that the solution is withdrawn from the m... | 09/07/2004 |
| 6783988 | Methods for quantitative and qualitative analyses of phospholipids using one-dimensional thin layer chromatography A highly sensitive and specific method for the detection and quantification of lipids is provided. Specifically, methods for the simultaneous detection and quantification of phospholipids extracted from mammalian tissues is described. The analytical methods provided... | 08/31/2004 |
| 6762057 | Separation apparatus including porous silicon column A sample separation apparatus including a porous, or rough, capillary column. The porous capillary column includes a matrix which defines pores, and may be formed from a material such as porous silicon. Alternatively, the capillary column may have a rough surface of... | 07/13/2004 |
| 6762058 | Examination method of buffer capacity of saliva and examination instrument of buffer capacity of saliva To provide an examination method of buffer capacity of saliva and an examination instrument of buffer capacity of saliva, by which the buffer capacity of saliva of a subject can be examined simply without being influenced by an amount of saliva and preciously withou... | 07/13/2004 |
| 6649598 | 4,7-dichlorofluorescein dyes as molecular probes Long wavelength, narrow emission bandwidth fluorecein dyes are provided for detecting specially overlapping target substances. The dyes comprise 4,7-dichlorofluoresceins, and particularly 2',4',5',7'-tetrachloro-4,7-dichloro-5-(and 6-) carboxyfluoresceins... | 11/18/2003 |
| 6599752 | Process for separating and analyzing hydrophobic proteins using thin layer chromatography This-layer chromatography is used to separate, identify and quantity hydrophobic protein, hydrophobic protein fragment, hydrophobic modified protein and hydrophobic peptide. A method is thus provided for determination of proteins and peptides which, due t... | 07/29/2003 |
| 6579719 | Retentate chromatography and protein chip arrays with applications in biology and medicine This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity conditions, and detecting the analytes retained on the sub... | 06/17/2003 |
| 6579723 | Method of recovering highly purified vWF or factor VIII/vWF-complex A method for purifying factor VIII/vWF complex or free vWF by immunoaffinity chromatography in a form suitable for use as a medicament. Factor VIII/vWF complex or free vWF is recovered from an immunoaffinity adsorbent by using an eluting agent containing ... | 06/17/2003 |
| 6534322 | Kits for early detection of heart disease The invention relates to methods, compositions, kits, and devices for detecting cardiac ischemia, hypoxia, or other causes of heart failure in a mammal by obtaining a test sample from a mammal, measuring a level of a non-polypeptidic cardiac marker in the... | 03/18/2003 |
| 6534323 | Compositions and methods for early detection of heart disease The invention relates to methods, compositions, kits, and devices for detecting cardiac ischemia, hypoxia, or other causes of heart failure in a mammal by obtaining a test sample from a mammal, measuring a level of a non-polypeptidic cardiac marker in the... | 03/18/2003 |
| 6429021 | Antioxidant activity profile assay The present invention provides an assay for detecting the presence of an array or a profile of antioxidant activity in any sources or products. In particular, the invention provides a method in which a sample is extracted with a polar, a non-polar and a s... | 08/06/2002 |
| 6420181 | Field microspot test method for on-site chemical testing A method, system and kit for detecting the presence of an analyte includes placing a solution containing the analyte in a microcapillary tube and placing the microcapillary tube in contact with a layer of sorbent material so that the solution is withdrawn... | 07/16/2002 |
| 6395178 | Thin porous layers for thin-layer chromatography Novel separation materials for thin layer chromatography are disclosed; these consist of a support and a separation medium layer and are obtainable by the following process steps: a) cleaning of the support; b) application of a liquid film comprising a polysil... | 05/28/2002 |
| 6333198 | Compound and its use A method of testing the purity or stability to degradation of a sample of lamotrigine or a pharmaceutical dosage form comprising lamotrigine comprises assaying the said sample for the presence of a compound selected from 3-amino-6-(2,3-dichlorophenyl)-1,2... | 12/25/2001 |
| 6331254 | Methods of separation and detection Methods which employ thin layer chromatography for separating and detecting hydrophobic target molecules are particularly useful in separating biologically relevant lipids. By utilizing non-destructive detection techniques, these methods also can be adapt... | 12/18/2001 |
| 6306665 | Covalent bonding of molecules to an activated solid phase material Microporous solid phase materials that are suitable for lateral flow and other assays for detecting the presence of analytes in test samples, that are stable under variations in humidity and, even after storage for extended periods of time, can form stabl... | 10/23/2001 |
| 6303081 | Device for collection and assay of oral fluids A device for collecting and transporting aqueous fluid from the oral cavity to a lateral chromatographic strip for test is disclosed. The lateral chromatographic strip is placed within and extend along a cavity defined in a housing. At least one inspectio... | 10/16/2001 |
| 6287521 | Methods and devices for obtaining and assaying mammary fluid samples for evaluating breast diseases, including cancer Non-invasive methods are provided for obtaining biological samples of mammary fluid or mammary fluid components by administering oxytocin to a patient to stimulate expression of mammary fluid. During or after mammary fluid expression, a biological sample ... | 09/11/2001 |