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Class 436/161 - INCLUDING CHROMATOGRAPHY


Subclass of Class 436 - Chemistry: analytical and immunological testing
Definition: Processes and compositions in which the result of a chemical
No. of patents: 960
Last issue date: 03/06/2012


1                      
NumberTitleIssue Date
8129194Method of simultaneous anion and cation suppression in a continuous electrodeionization apparatus
The present invention pertains to a method of ion chromatography wherein a specialized electrodeionization (EDI) apparatus is used for simultaneous ion suppression of cations from a flowing base containing an anion sample of interest and ion suppression of anions fr...
03/06/2012
8114678Multi-dimensional high performance liquid chromatographic separation technique (STAR7) for quantitative determinations of 7 fractions in heavy petroleum streams boiling above 550 degrees F
The present invention provides quantitation of seven classes of compounds (saturates, 1-4+ ring aromatics, sulfides, and polars) present in petroleum streams boiling from 550-1050° F. Operating the present invention in the preparative mode will allow us to load and...
02/14/2012
8110403Immunoassay method
It is an object of the present invention to provide an immunoassay method which is capable of simultaneous quantification of a plurality of test substances under a same analysis condition, through adjustment of the measurement sensitivity/range by simply varying the...
02/07/2012
8101422Multidimensional chromatography apparatus and method
An ion chromatography apparatus comprising: (a) a first chromatography column, (b) a second chromatography column, the volume of the second column being no greater than 0.9 times the volume of the first; and (c) valving disposed between said first and second columns...
01/24/2012
8088627On-line gas chromatographic analysis of airborne particles
A method and apparatus for the in-situ, chemical analysis of an aerosol. The method may include the steps of: collecting an aerosol; thermally desorbing the aerosol into a carrier gas to provide desorbed aerosol material; transporting the desorbed aerosol material o...
01/03/2012
8076152Microfluidic devices comprising fluid flow paths having monolithic chromatographic material
Aspects of the invention include a microfluidic device having a fluid flow path and a monolithic chromatographic material covalently bound to at least a portion of a polymeric surface of the fluid flow path. Aspects of the invention further include methods of making...
12/13/2011
8067243Methods and systems for analyzing medication levels in a sample
Methods and systems for assessing patient compliance with opioid drug therapy are provided. A liquid chromatography tandem mass spectrometer (LC/MS/MS) can be used to simultaneously detect a set of measurements including an amount of at least ten opioids (and their ...
11/29/2011
8062898Selection and rational development of solvent systems in counter-current chromatograph
Application of a reference mixture of natural products for systematic analysis and comparison of the properties of biphasic solvent systems in counter-current/partition chromatography. Because the reference mixture is comprised of compounds with varying polarities, ...
11/22/2011
8062899Identification and quantitative determination of major chemical contaminants associated with L-Tryptophan
An improved chromatographic method for the separation, identification and quantification of contaminants associated with Eosinophelia-Myalgia Syndrome (EMS) includes a high pressure liquid chromatography (HPLC) method which utilizes a silica-based column and a gradi...
11/22/2011
8030087Method for analyzing concentration of glue contained in electrolyte solution
The purpose of the present invention is to provide a method to more easily analyze the concentration of glue in an electrolyte solution, while suppressing the degradation of glue during the analysis. There is provided a method for analyzing the concentration of glue...
10/04/2011
8021889Chromatographic material for the absorption of proteins at physiological ionic strength
Ion exchange and hydrophobic interaction chromatographic materials are constructed by tethering a terminal binding functionality to a solid support via a hydrophobic linker. The backbone of the linker typically comprises sulfur-containing moieties. Suitable terminal...
09/20/2011
7985593Apparatus and method for polymer characterization
Apparatus for GPC/TREF and TREF/GPC characterization of a polymer sample. The apparatus provides for the automated and integrated use of multiple TREF columns and a GPC system employing a multiple flow through detectors. In addition, a method for TREF/GPC characteri...
07/26/2011
7977114Method and apparatus for monitoring processes using a single detector
Embodiments of the invention feature methods and apparatus for the efficient utilization of detectors and other components. The apparatus comprises a pump for receiving and propelling one or more samples in a fluid path. The apparatus further comprises a valve eleme...
07/12/2011
7964411Membrane based concentrators
A sample concentrator for concentrating analytes in a solvent-containing liquid sample stream, including concentrator housing having a sample stream flow channel and a gas stream flow channel having an inlet and an outlet, a heater for gas in the gas stream conduit,...
06/21/2011
7960180Methods and apparatus to capture and release microbe particles using amino-functionalized silica
Methods and apparatus to capture and release microbe particles using amino-functionalized silica substrates are described. An example apparatus adapted to capture a microbe particle includes a silica substrate and a positively charged material to at least partially ...
06/14/2011
7932093One step oligochromatographic device and method of use
The present invention relates to methods and devices for detecting one or more analytes in a biological sample, preferably a clean liquid sample. This invention in particular relates to improved rapid tests such as “dipsticks”, “lateral flow” devices and “...
04/26/2011
7923259Platform for analysis liquid samples
The present application relates to apparatus for sampling and analysis of analytes in a liquid sample. A liquid sample is pre-concentrated using a chromatographic column prior to analysis via a two stage analysis apparatus. A high-performance liquid chromatography s...
04/12/2011
7897405Method for identifying the elution time of an analyte
A method for determining a time of elution of a peptide of interest from a liquid chromatography column includes a step of obtaining chromatographic data for each of a plurality of candidate fragment ions of the peptide of interest. A time along a common chromatogra...
03/01/2011
7897404Conjugates of defined stoichiometry
The invention relates to a process for the production of a biomolecule-linker conjugate of uniform stochiometry. It especially relates to a conjugate consisting of a biomolecule of a molecular weight between 5 kD and 500 kD and a hydrophilic linker molecule said lin...
03/01/2011
7892847Method and apparatus for countercurrent chromatography
A countercurrent chromatography apparatus includes a plurality of plates, at least one plate (16) having first and second interleaved spiral flow channels (52, 54, 56, 58) therein. Each spiral flow channels (52, 54, 56, 58) has a first end (I
02/22/2011
7892848Method of ion chromatography wherein a specialized electrodeionization apparatus is used
The present invention pertains to a method of ion chromatography wherein a specialized electrodeionization (EDI) apparatus is used for (1) the preparation of a pure acid or pure base for use as an eluent in a chromatographic separation column and/or (2) for ion supp...
02/22/2011
7833803Analysis of liquid chromatography eluates
When analysing saccharides by HPAEC, the eluate from the column is typically analysed using a amperometric detector. According to the invention, amperometric detection is coupled with ultraviolet detection, with both methods being applied to the eluate. Thus the inv...
11/16/2010
7767463Method for screening mobile phases in chromatography systems
A method and system of screening or selecting a mobile phase eluent for a chromatography column is provided. A sample for chromatographic analysis or purification is combined with a solvent and passed through a membrane. A pressure measurement is taken of the sample...
08/03/2010
7767462Electrolytic eluent generator and method of use
An acid or base is generated in an aqueous solution by the steps of: (a) providing a source of first ions adjacent an aqueous liquid in a first acid or base generation zone, separated by a first barrier (e.g., anion exchange membra...
08/03/2010
7732216System and method for testing chromatography media and devices
Methods for testing the chromatography type and/or the integrity of a chromatography membrane or monolith, preferably, for testing the chromatography type and integrity of a chromatography device comprising a chromatography membrane or chromatography monolith while ...
06/08/2010
7704749Aqueous stream purifier and method of use
An electrolytic method is provided for purifying an aqueous stream, including at least one contaminant ion. In one embodiment, the eluent stream flows through a purifying flow channel, including ion exchange bed, an electric field is applied through the flowing elue...
04/27/2010
7678579Method for analysis metabolite difference between biological samples
Disclosed is a method of extracting all metabolites existing in a biological sample to detect a comprehensive difference between metabolites of a control group and a test group, thereby verifying significance thereof. More particularly, the invention comprises a fir...
03/16/2010
7662638Method for chromatographic finger printing and standardization of single medicines and formulations
The present invention provides a method for the chromatographic fingerprinting, chemical and therapeutic standardization, bar-coding of the fingerprints and preparation of a data base for Enterprise Resource Planning (ERP) and Customer Relationship Management (CRM) ...
02/16/2010
7618826Membrane suppressor with an outlet substantially non-retentive for ionic species
An apparatus for ion chromatography comprising a suppressor comprising a housing and a liquid conduit segment disposed in the housing, the liquid conduit segment including a membrane, the membrane having an inlet section adjacent the inlet of the conduit segment and...
11/17/2009
7601543Method of modulating a second carrier for partial modulation via pulsed flow modulator for comprehensive two-dimensional liquid or gas chromatography
This invention is a method and device for use with multi-dimensional chromatography that utilizes partial modulation. An analyte-bearing sample is subjected to a first dimension of chromatography. Thereafter the separated analyte-bearing sample is diluted with a mod...
10/13/2009
7585679Ion chromatography system with flow-delay eluent recycle
A chromatographic method including chromatographically separating sample ionic species in an eluent stream, detecting the separated sample ionic species, catalytically combining hydrogen and oxygen gases or catalytically decomposing hydrogen peroxide in a catalytic ...
09/08/2009
7507586Partial modulation via pulsed flow modulator for comprehensive two-dimensional liquid or gas chromatography with multiple modulation periods
This invention is a method and device for use with multi-dimensional chromatography that utilizes partial modulation with multiple secondary retention times. An analyte-bearing sample is subjected to a first dimension of chromatography. Thereafter the separated anal...
03/24/2009
7459313Method for measuring effective temperature inside a sealed container
A method of measuring the effective temperature inside a sealed container having a headspace is provided. A liquid solvent is added to the container, and a solid compound is added to the liquid solvent to create a saturated solution. Vapor of the saturated solution ...
12/02/2008
7442556Microfluidic-based electrospray source for analytical devices with a rotary fluid flow channel for sample preparation
This invention provides microfluidic devices and methods for using the same. Microfluidic devices of the present invention comprises a first elastic layer, a fluid flow channel within the elastic layer; and a means for providing a fluid sample from the fluid flow ch...
10/28/2008
7439079Assay devices having detection capabilities within the hook effect region
A lateral flow assay device for detecting the presence or quantity of an analyte within a test sample is provided. The device utilizes multiple zones, one of which serves as an indicator of whether or not the analyte in the test sample is within the “hook effect...
10/21/2008
7435597Assays for zero-valent transition metals in sedimentary rocks using carbon monoxide with application to oil and gas exploration
The present invention is directed to novel assays for zero-valent transition metals. The novel assays of the present invention are generally methods or processes for quantitatively and/or qualitatively evaluating the presence of zero-valent transition metals on and/...
10/14/2008
7435598Catalyst testing apparatus and process
An apparatus and process are described in which a plurality of preloaded catalyst samples tubes can be serially and automatically moved from a support to a reaction zone where each catalyst sample can be heated and a preheated reagent feed contacted with the sample ...
10/14/2008
7431841Method for the extraction of components made from organic material
The invention relates to a method for the extraction of components made from organic material, comprising the step of extraction with a single-phase mixture of 50 to 90 vol. % methanol and 50 to 10 vol. % water and optionally 0 to 40 vol. % of a further solvent or s...
10/07/2008
7419831Method and apparatus for determination of water and for normal phase liquid chromatography
A method for calibrating an analysis instrument, e.g., a gas chromatograph, for water analysis that includes four steps. The first step is to continuously remove water from a liquid that contains water to produce a liquid containing a reduced amount of water such as...
09/02/2008
7419830Plural reaction chamber catalytic testing device and method for its use in catalyst testing
A catalytic testing device comprising a reaction block comprising a set of reaction chambers, each chamber comprising a fluid inlet and outlet connected to an outgoing fluid duct connected to analysis means, fluid ...
09/02/2008
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