Did You Know...
...that in 1800 ether was first used by partyers as a fun diversion? Sniffing the gas led to hilarious and raucous laughter as people watched each other become more and more intoxicated and silly. Several doctors independently realized the value ether would have to anesthetize surgery patients. Of those who claimed rights to the "discovery," none had a happy ending. One had a seizure and died defending his rights. Another spent his life in an asylum because he had been denied acclaim. A third became addicted to chloroform and, in a New York City jail, he soaked a cloth in the drug, severed an artery and bled to death.
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| Number | Title | Issue Date |
| 7326576 | Raman spectroscopic monitoring of hemodialysis Spectroscopic systems and methods are disclosed for determining levels of at least one analyte in blood undergoing hemodialysis. In one aspect, the invention employs Raman spectroscopy to monitor and/or control hemodialysis. In one embodiment, the system uses a lase... | 02/05/2008 |
| 7229835 | Amine detection method and materials A compound linked to a solid support (R) through a divalent linker moiety (X) and which is represented by the following formula: is disclosed. In particular, the 1-hydroxybenzotriazole-6-carboxylic acid is direct... | 06/12/2007 |
| 7224070 | Plurality of semiconductor die in an assembly The present invention provides methods and apparatus related to preventing adhesive contamination of the electrical contacts of a semiconductor device in a stacked semiconductor device package. The methods and apparatus include providing a first semiconductor device... | 05/29/2007 |
| 7153693 | Method and apparatus for determining urea concentration A method for determining a urea concentration in an aqueous solution containing urea, includes: hydrolyzing the urea in the aqueous solution, measuring an electric conductivity χ of the aqueous solution, and determining the urea concentration in the aqueous solutio... | 12/26/2006 |
| 7150997 | Multiplexed active biologic array A method of addressing and driving an electrode array includes the step of addressing one or more electrodes within the array using a plurality of row and column lines. In one aspect of the method, a value corresponding to a voltage is stored in a local memory assoc... | 12/19/2006 |
| 7118916 | Method of reducing analysis time of endpoint-type reaction profiles Methods, devices and kits for facilitating medical diagnostic assays and reducing the time required for taking of such assays. The methods comprise initiating a reaction, obtaining at least three measurements, at three different time points, of a value or level of a... | 10/10/2006 |
| 7101717 | Addressable biologic electrode array An addressable biologic electrode array includes an array of electrodes disposed on a support, the array of electrodes being selectively addressed and driven using a memory associated with each electrode of the array, the driven electrodes being driven at one of a p... | 09/05/2006 |
| 7056656 | Tat-derived oligourea and its method of production and use in high affinity and specific binding HIV-1 TAR RNA This invention relates to the use of oligourea molecules to specifically inhibit protein-nucleic acid interactions. In particular, it provides an oligourea molecule that competes with the Tat molecule for the TAR RNA of HIV-1. Also provided is a method specifically ... | 06/06/2006 |
| 7045097 | Biologic electrode array with integrated optical detector A biologic electrode array is formed on a semiconductor substrate. A matrix of electrode sites is disposed on the semiconductor substrate. A matrix of optical detectors is disposed beneath the electrode sites in the semiconductor substrate, wherein each electrode si... | 05/16/2006 |
| 6920399 | Method and apparatus for determining the composition of fluids A method and apparatus for analyzing a fluid to obtain the concentrations of N of its components, N being at least three. The method comprises the steps of bringing a sample of the fluid to a plurality of successive temperatures, measuring a combined total of at lea... | 07/19/2005 |
| 6872573 | Fluorescent creatinine assay A method of detecting creatinine in body fluids using an indicator which produces a fluorescent response when oxidized in the presence of a copperII/creatinine complex. A preferred indicator is 4-(1-methylhydrazino)-7-nitro benzooxadiazole (MNBDH). ... | 03/29/2005 |
| 6867048 | Multiplexed active biologic array A method of addressing and driving an electrode array includes the step of addressing one or more electrodes within the array using a plurality of row and column lines. In one aspect of the method, a value corresponding to a voltage is stored in a local memory assoc... | 03/15/2005 |
| 6773922 | Reagentless analysis of biological samples Apparatus and method for determining at least one parameter, e.g., concentration, of at least one analyte, e.g., urea, of a biological sample, e.g., urine. A biological sample particularly suitable for the apparatus and method of this invention is urine. In general,... | 08/10/2004 |
| 6682936 | Addressable biologic electrode array A biologic electrode array assembly is formed on an integrated circuit chip that includes an array of electrodes. At least one metal oxide semiconductor (MOS) switch is coupled to at least one of the electrodes within the array. A voltage line is provided... | 01/27/2004 |
| 6521184 | Apparatus for measuring a decomposable compound in solution Methods and apparatus for measuring the concentration of decomposable substances, such as urea, are disclosed. The disclosed methods include adding a gaseous buffer, such as CO2, to the solution containing the decomposable compound, measuring t... | 02/18/2003 |
| 6287851 | Sensor for analyzing components of fluids A sensor is provided that is useful for assaying a component of a biological fluid such as blood, urine or milk, and comprises a chamber having an inlet, a liquid containing portion and a vapor containing portion. The liquid and vapor containing portions ... | 09/11/2001 |
| 6258606 | Multiplexed active biologic array An improved biologic electrode array and methods for manufacturing and using the same. In one aspect, a matrix of electrodes each coupled to a respective sample-and-hold circuit is provided. The electrodes and sample-and-hold circuits are integral and for... | 07/10/2001 |
| 6162647 | Method for removing interfering substances from a urine sample using a chemical oxidant Urine samples are made free of potentially interfering substances, such as alkaloids or pharmaceuticals, by contacting the urine sample with an amount of a chemical oxidizing agent, while retaining the physical indicia characteristic of urine to allow the... | 12/19/2000 |
| 6114176 | Method for measuring the concentration of a substance in a solution Methods and apparatus for measuring the concentration of decomposable substances, such as urea, are disclosed. The disclosed methods include adding a gaseous buffer, such as CO2, to the solution containing the decomposable compound, measuring t... | 09/05/2000 |
| 6096575 | Optimum condition detection method for flip-chip An optimum condition detection method for flip-chip bonding that facilitates simple detection of optimum pressure and heating temperature for flip-chip bonding implemented by use of bonding material is provided. Pressure applied to a semiconductor chip is incr... | 08/01/2000 |
| 6087182 | Reagentless analysis of biological samples Apparatus and method for determining at least one parameter, e. g., concentration, of at least one analyte, e. g., urea, of a biological sample, e.g, urine. A biological sample particularly suitable for the apparatus and method of this invention is urine.... | 07/11/2000 |
| 5968835 | Method for estimating nitric acid and nitrous acid ions To estimate nitric acid ions and nitrous acid ions in a sample solution, a method is proposed which comprises the steps of (a) feeding both the sample solution and a reducing agent to an acidic solution which is flowing in a thin pipe; (b) positively mixi... | 10/19/1999 |
| 5965452 | Multiplexed active biologic array An improved biologic electrode array and methods for manufacturing and using the same. In one aspect, a matrix of electrodes each coupled to a respective sample-and-hold circuit is provided. The electrodes and sample-and-hold circuits are integral and for... | 10/12/1999 |
| 5945343 | Fluorescent polymeric sensor for the detection of urea The present invention provides a urea sensor material having a first layer of a protonated pH sensitive fluorophore immobilized in a hydrophobic polymer, wherein the fluorophore can react quantitatively with ammonia and the transducing moiety of the fluor... | 08/31/1999 |
| 5888828 | Kit for measuring urea nitrogen A method of measuring urea nitrogen on the basis of the ultraviolet absorption of urease-GLDH by a reaction rate method, which method not only permits accurate measurement of a sample containing a high concentration of urea nitrogen but also permits accur... | 03/30/1999 |
| 5882598 | Wafer gap conductivity cell for characterizing process vessels and semiconductor fabrication processes and method of use A conductivity cell for use in determining ionic concentrations in the gap between two semiconductor substrates or wafers. The wafer gap conductivity cell is composed of two flat electrodes separated by a fixed gap. The electrodes are fabricated from wafe... | 03/16/1999 |
| 5882937 | Ammonia monitor Ammonia monitor and method of use are disclosed. A continuous, real-time determination of the concentration of ammonia in an aqueous process stream is possible over a wide dynamic range of concentrations. No reagents are required because pH is controlled ... | 03/16/1999 |
| 5858796 | Reagent and method for screening of the functional condition of the body Reagent and method are offered for the screening of the functional condition of the body by the person's saliva. Reagent presents itself as an H2O solution, containing ions of Fe3+, chloride ions and multi-atom alcohol .n the concentrations 0.05-3.0M; 0.0... | 01/12/1999 |
| 5837199 | Measurement apparatus for analyzing fluids The invention relates to a measurement apparatus (1) for analysing fluids, comprising a container (3) in the form of a syringe, into which a fluid may be taken in via an intake device (14) through at least one opening (5), and further comprising a sensor ... | 11/17/1998 |
| 5830768 | Carbamazepine derivatives used in particle reagents The present invention provides a novel carbamazepine hydrazide compound suitable for covalent attachment to a polymer particle reagent, having the general formula ##STR1## The present invention also provides a novel carbamazepine acid compound s... | 11/03/1998 |
| 5798267 | Method for determining alcohol consumption rates A method for assessing or determining alcohol consumption rates including using a blood specimen from a human subject to develop an individual blood constituent panel; comparing the individual panel with a reference blood constituent panel to provide cate... | 08/25/1998 |
| 5792668 | Radio frequency spectral analysis for in-vitro or in-vivo environments Concentration of a target chemical in the presence of other substances in a specimen is determined by subjecting the specimen to radio frequency electromagnetic components, sequentially or otherwise, ranging to about 5 GHz. The reflected and/or transmitte... | 08/11/1998 |
| 5709837 | Dry analytical element containing ampholyte A dry analytical element comprising at least one water-permeable reagent layer and a porous spreading layer laminated in this order on a support, wherein at least one layer which is the water-permeable reagent layer, the porous spreading layer or an optio... | 01/20/1998 |
| 5698083 | Chemiresistor urea sensor A sensor to detect and quantify urea in fluids resulting from hemodialysis procedures, and in blood and other body fluids. The sensor is based upon a chemiresistor, which consists of an interdigitated array of metal fingers between which a resistance meas... | 12/16/1997 |
| 5668014 | Device and method for estimating three nitrogen-including ionic substances in water To estimate nitric acid ions and nitrous acid ions in a sample solution, a method is proposed which comprises the steps of (a) feeding both the sample solution and a reducing agent to an acidic solution which is flowing in a thin pipe; (b) positively mixi... | 09/16/1997 |
| 5662806 | Hemodialysis monitoring system for hemodialysis machines An improved on-line real time hemodialysis monitoring system for hemodialysis treatment. The hemodialysis monitoring system quantitates the rate and amount of a constituent, such as urea, removed during the hemodialysis treatment by measuring the constitu... | 09/02/1997 |
| 5620900 | Means and method for the determination of ammonium ions The invention relates to an absorptive support and a method for the determination of ammonium ions in aqueous solutions by the Berthelot method using one absorptive support. The absorptive support is impregnated with a phenol derivative.... | 04/15/1997 |
| 5606116 | Chromatogenous testing system for urinalysis A testing system for urinalysis is provided comprising a support member which carries a developing phase, a reagent carrying means, a urine applying section, and a urine-reagent developing area. In order to prevent inaccurate test results which may result... | 02/25/1997 |
| 5518623 | Hemodialysis monitoring system for hemodialysis machines An improved on-line real time hemodialysis monitoring system for hemodialysis treatment. The hemodialysis monitoring system quantitates the rate and amount of a constituent, such as urea, removed during the hemodialysis treatment by measuring the constitu... | 05/21/1996 |
| 5508203 | Apparatus and method for radio frequency spectroscopy using spectral analysis A source of high frequency electromagnetic radiation is coupled to a specimen containing a target chemical whose presence and/or concentration is to be ascertained. Preferably the source radiation includes a plurality of high frequency spectra, at least o... | 04/16/1996 |
