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| Number | Title | Issue Date |
| 7442525 | Method for expressing HIV polypeptides Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare... | 10/28/2008 |
| 7408053 | Recombinant DNA constructs for GAG polypeptides and polypeptides produced thereby Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare... | 08/05/2008 |
| 7374877 | Amplification of HIV-1 gag sequences for detection of sequences associated with drug-resistance mutations Sequences of nucleic acid oligonucleotides for amplifying different portions of gag and pol genes of HIV-1 and for detecting such amplified nucleic acid sequences are disclosed. Methods of amplifying and detecting HIV-1 nucleic acid in a biological sample using the ... | 05/20/2008 |
| 7309611 | Prewetting stop flow test strip A test strip and method for detecting an analyte present in a sample. The test strip comprising: a buffer addition zone to which a buffer may be added; an absorbent zone proximal to the buffer addition zone; one or more test zones distal to the buffer addition zone,... | 12/18/2007 |
| 7285271 | Antigenic composition comprising an HIV gag or env polypeptide Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare... | 10/23/2007 |
| 7273695 | HIV immunoassays using synthetic envelope polypeptides Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare... | 09/25/2007 |
| 7270995 | Analyzing device The present invention is an analytical device which comprises a porous piece assembly consisting of a liquid reagent-receiving porous piece (1), a labeled substance-retaining piece (2), a test piece (3) comprising a detection site (4) and... | 09/18/2007 |
| 7229839 | Bidirectional lateral flow test strip and method A test strip adapted to receive a sample and detect an analyte therein is provided. The test strip comprises a sample addition zone to which a sample may be added; an absorbent zone proximal to the sample addition zone; one or more test zones distal to the sample ad... | 06/12/2007 |
| 7205101 | Human immunodeficiency virus (HIV) nucleotide sequences, recombinant polypeptides, and applications thereof Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare... | 04/17/2007 |
| 7097971 | HIV-1 peptide, antigen, immunogenic composition, diagnostic method and immunoassay kit The present invention comprises novel and modified peptides capable of inducing a HIV-1 specific immune response without antagonizing the cytotoxic T-cell activity in order to achieve an effective prophylactic and therapeutic vaccine against HIV. The peptides are ba... | 08/29/2006 |
| 7087377 | Method and kit for detection of tat protein with anti-tat oyi antibodies The invention relates to an anti HIV 1 vaccine comprising the entire or part of the Tat HIV 1 protein, in addition to the identification of said protein in individuals affected by HIV. The Tat protein is a protein of the HIV 1 Oyi variant. ... | 08/08/2006 |
| 7074554 | Antibodies specific for NEBR1 and methods of use thereof Materials and methods are provided to inhibit HIV replication in targeted host cells. ... | 07/11/2006 |
| 7070943 | Detection of protein conformations in single cells Methods, reagents, and kits are provided that permit flow cytometric determination of the phosphorylation status of retinoblastoma susceptibility gene protein (pRB) in individual cells. Methods are described that permit the hypophosphorylated, active, form of pRB to... | 07/04/2006 |
| 6974866 | Retrovirus from the HIV type O and its use (MVP-2901/94) A novel HIV type O immunodeficiency virus is disclosed which has the designation MVP-2901/94 and which has been deposited with the European collection of animal Cell Cultures (ECACC) under No. V 950121601. The characteristic antigens which can be obtained from the v... | 12/13/2005 |
| 6949337 | Cellular receptor for HIV-1 Vpr essential for G2/M phase transition of the cell cycle The present invention provides methods of identifying anti-HIV compound by contacting human Vpr Interacting Protein (hVIP), or a fragment thereof known to interact with Vpr, with Vpr, or a fragment thereof known to interact with hVIP in the presence of a test compou... | 09/27/2005 |
| 6946254 | Amplification of HIV-1 gag sequences for detection of sequences associated with drug-resistance mutations Sequences of nucleic acid oligonucleotides for amplifying different portions of gag and pol genes of HIV-1 and for detecting such amplified nucleic acid sequences are disclosed. Methods of amplifying and detecting HIV-1 nucleic acid in a biological sample using the ... | 09/20/2005 |
| 6902884 | Method and tool for prognosticating HIV infection in a subject by measuring soluble urokinase plasminogen activator receptor, degradation products thereof, and urokinase plasminogen activator receptor Method of diagnosing and/or prognosticating HIV infection in a subject comprising the steps of: (a) performing in vitro a measurement of the level of a marker in the form of (i) urokinase plasminogen activator receptor (uPAR), (ii) soluble urokinase plasminogen acti... | 06/07/2005 |
| 6858400 | Detection of surface-associated human leukocyte elastase In order to accurately and reliably quantitate HLE on the plasma membranes of the lymphocytes and mononuclear phagocytes, a test sample containing the lymphocytes and mononuclear phagocytes is initially treated with a first antiserum specific for CD4 receptors on th... | 02/22/2005 |
| RE38688 | Sheet-like diagnostic device A solid diagnostic device for the quantitative determination of substances of biological affinity in biological fluids is described. A process is also described in which the biological fluid is brought into contact with a specific functional sector of the device, th... | 01/18/2005 |
| 6815217 | Use of check surfaces for identifying disturbing samples in a detection procedure A solid phase with at least one test area is described which contains reagents for the detection of at least one analyte in a sample, wherein the solid phase additionally comprises at least one control area for the detection of interfering reactions. ... | 11/09/2004 |
| 6767710 | Prewetting stop flow test strip A test strip and method for detecting an analyte present in a sample. The test strip comprising: a buffer addition zone to which a buffer may be added; an absorbent zone proximal to the buffer addition zone; one or more test zones distal to the buffer addition zone,... | 07/27/2004 |
| 6699656 | Treatment and prevention of HIV infection by administration of derivatives of human chorionic gonadotropin The present invention relates to ଲ-hCG, particularly ଲ-hCG proteins having a sequence of amino acids 41-54, 45-54, 47-53, 45-57 and 45-58 and analogs and derivatives thereof. The invention further relates to methods of treatment and prevention... | 03/02/2004 |
| 6664042 | Determining viral load in double negative T cells The present invention provides a method for determining viral load in a patient infected with human immunodeficiency virus, which is useful in patients where viral loads are not detectable in plasma. The levels of human immunodeficiency virus are measured... | 12/16/2003 |
| 6653066 | Device and method for detecting polyvalent substances Disclosed is a device and method of use for detecting polyvalent analytes such as antibody to the AIDS virus, utilizing an inverse sandwich method. The test device comprises a first substance having an epitope, bound to a label and capable of moving withi... | 11/25/2003 |
| 6582928 | Carbohydrate-directed cross-linking reagents The invention provides heterobifunctional cross-linking reagents and methods of using the cross-linking reagents. The cross-linking reagents of the invention combine a nucleophilic hydrazide residue with an electrophilic maleimide residue allowing couplin... | 06/24/2003 |
| 6582920 | Amplification of HIV-1 RT sequences for detection of sequences associated with drug-resistance mutations Sequences of nucleic acid oligonucleotides for amplifying different portions of gag and pol genes of HIV-1 and for detecting such amplified nucleic acid sequences are disclosed. Methods of amplifying and detecting HIV-1 nucleic acid in a biological sample... | 06/24/2003 |
| 6548635 | Retrovirus from the HIV type O and its use (MVP-2901/94) A novel HIV type O immunodeficiency virus is disclosed which has the designation MVP-2901/94 and which has been deposited with the European Collection of Animal Cell Cultures (ECACC) under No. V 950121601. The characteristic antigens which can be obtained... | 04/15/2003 |
| 6541609 | HIV-2 peptides A substantially pure polypeptide having at least one antigenic determinant that is substantially identical to an antigenic determinant of a protein from a cell line infected with simian T-lymphotrophic virus-III or human T-lymphotrophic virus-IV (HTLV-IV)... | 04/01/2003 |
| 6528323 | Bidirectional lateral flow test strip and method A test strip adapted to receive a sample and detect an analyte therein is provided. The test strip comprises a sample addition zone to which a sample may be added; an absorbent zone proximal to the sample addition zone; one or more test zones distal to th... | 03/04/2003 |
| 6518015 | Peptide comprising the sequence CAFRQVC and methods using it This invention includes a peptide comprising the sequence CAFRQVC and an antigenic composition using the same. It also includes an in vitro method of detecting HIV-1 and HIV-2 antibodies in a sample using the peptide, and a kit for carrying out the method... | 02/11/2003 |
| 6511801 | HIV-1 group O antigens and uses thereof The claimed invention relates to an HIV-1 group O envelope antigen comprising SEQ ID NO: 100, and the use of said antigen as a reagent in the diagnosis of HIV-1 group O infection, and a kit therefore.... | 01/28/2003 |
| 6503702 | Rapid immunoassay for detection of antibodies or antigens incorporating simultaneous sample extraction and immunogenic reaction The present invention is drawn to an immunoassay capable of the rapid detection of a variety of test substances that may be present in a test sample. One feature of the invention is that extraction or isolation of the test substance occurs simultaneously ... | 01/07/2003 |
| 6489131 | Interference reduction by rheumatoid factors The invention concerns a method for the determination of an analyte in which rheumatoid factors or rheumatoid-factor-like substances are added as an interference reducing reagent to reduce of avoid a hook effect. The invention in addition concerns suitabl... | 12/03/2002 |
| 6465172 | HIV immunogenic complexes comprising GP120 covalently bound to CD4 or concanavalin A A vaccine and a method of raising neutralizing antibodies against HIV infection. The vaccine comprises a complex of gp120 covalently bonded to CD4 or to succinyl concanavalin A. Also disclosed are immunological tests using the complex or antibody thereto ... | 10/15/2002 |
| 6465173 | Anti-idiotypic antibody and its use in diagnosis and therapy in HIV-related disease The present invention provides an anti-idiotypic antibody having specific reactivity with an idiotope common to more than one type of anti-HIV-1 antibody, and having no specific reactivity with non-HIV-1 antibodies. The present invention provides methods ... | 10/15/2002 |
| 6458548 | Containers and kits for the determination of cell functions, and method for the determination thereof A container for measurement of cell functions, for use in the determination of a physiologically active substance produced by blood cells, is constituted such that an amount of material capable of inducing production of the physiologically active substanc... | 10/01/2002 |
| 6383740 | Methods for simultaneously detecting both members of a binding pair Methods and kits for simultaneously measuring both members of a binding pair are described.... | 05/07/2002 |
| 6319665 | Home test kit and method with telephone verification of results Self-testing for a disease or physiological condition is achieved by having the individual being tested obtain a sample of physiological fluid, e.g., blood, urine, sputum or saliva, from him or herself. The sample is introduced into an assay system which ... | 11/20/2001 |
| 6294341 | Method for detecting a substance having an activity to inhibit HIV infection using immunoassay and variant protein used for said method The present invention relates to a method for detecting a substance having an activity to inhibit HIV infection rapidly, economically and safely. The present invention uses the characteristics that if a function of transmembrane protein gp41 of HIV is inh... | 09/25/2001 |
| 6277971 | Nef-attachable protein, DNA encoding the protein and a monoclonal antibody against said protein A monoclonal antibody specific to Nap was prepared by using a crude membrane fraction from a cell line which has a high affinity to Nef as an antigen. A cDNA clone which encodes Nap was obtained by screening a cDNA library of said cell line utilizing the ... | 08/21/2001 |
