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Neuroimaging as a Marketing Tool
Neuroimaging as a means for validating whether a stimulus such as advertisement, communication, or product evokes a certain mental response such as emotion, preference, or memory, or to predict the consequences of the stimulus on later behavior such as consumption or purchasing.
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| Number | Title | Issue Date |
| 7393662 | Human EPO mimetic hinge core mimetibodies, compositions, methods and uses The present invention relates to at least one novel human EPO mimetic hinge core mimetibody or specified portion or variant, including isolated nucleic acids that encode at least one EPO mimetic hinge core mimetibody or specified portion or variant, EPO mimetic hing... | 07/01/2008 |
| 7166423 | Direct selection of cells by secretion product Cells can be labeled with products which they secrete and release in an efficient manner by coupling the cells at their surface to a specific binding partner for the product and allowing the product to be captured by the specific binding partner as it is secreted an... | 01/23/2007 |
| 7018809 | Expression of functional antibody fragments Methods for the high yield production of antibody Fv-containing polypeptides, especially Fab′ and F(ab′)2 antibody fragments are provided. Expression of heavy and light chain Fv in a microbial secretory system is followed by recovery of Fv from the pe... | 03/28/2006 |
| 6867007 | Binary or polynary targeting and uses thereof Effector functions are provided to a desired target with improved specificity by use of two or more complementary targeting components. The targeting components assemble a functional moiety at the target. At the target, the functional moiety itself provides an effec... | 03/15/2005 |
| 6746847 | Diagnostic assay for human matrix Gla-protein and its use as a biomarker A diagnostic assay, preferably immunoassay, is provided for the detection and determination of MGP in a human serum sample, which comprises the use of one or more antibodies, in particular monoclonal antibodies, specifically recognising epitopes on and/or conformati... | 06/08/2004 |
| 6673562 | Differential immunoassay The invention provides assay methods and kits that in general measure the level of a first analyte in a sample reduced by the level of a second analyte present in the same sample. In one embodiment, where levels of a first analyte from a first source is d... | 01/06/2004 |
| 6613746 | AGP-antibody fusion proteins and related molecules and methods Disclosed is a method of inhibiting the binding of a cell bearing a cell adhesion protein to a molecule or cell bearing a carbohydrate determinant specific for the cell adhesion molecule. The method involves contacting the cell adhesion protein-bearing ce... | 09/02/2003 |
| 6582924 | Hair analysis method A method for the direct analysis of analyte in keratinized structures, e.g., hair, fingernails and toenails, which comprises preparing a mixture containing a low redox potential compound such as dithiothreitol or dithioerythritol, an enzyme suitable for t... | 06/24/2003 |
| 6531278 | Ligand-DNA composition for capture and detection of contaminants on a solid surface Compositions and methods of use thereof for capture and detection of selected molecules are described. In one embodiment, a first composition includes a ligand component, such as an antibody coupled to a nucleic acid component. An a preferred embodiment, ... | 03/11/2003 |
| 6509451 | Cross-linked antibodies and processes for their preparation Bis-maleimido cross-linking reagents join labelled antibodies having at least one sulphide interchain bridge. The conjugates have an enhanced binding capacity and have good blood clearance in vivo. The conjugates are of use in the diagnosis and therapy of... | 01/21/2003 |
| 6482648 | Stable troponin preparation and the use thereof as a calibrator/control in immunoassays The present invention relates to methods for the production of a stable troponin preparation and its use as a calibrator and/or control in immunoassays. The formulation is prepared from mammalian, preferably bovine, heart tissue which provides a calibrato... | 11/19/2002 |
| 6451545 | Monoclonal antibody specific to anti-human fibrin monomer, process for producing the same, hybridomas, and immunoassay method Provided are a monoclonal antibody making it possible to detect a native fibrin monomer, which is produced at the initial state of blood coagulation, and soluble fibrin; a hybridoma; and an immunoassay for detecting the initial stage of blood coagulation ... | 09/17/2002 |
| 6410251 | Method for detecting or assaying target substance by utilizing oxygen electrode A method for detecting or assaying one constituting member in a specific binding pair, for example, the antigen in an antigen/antibody pair, by utilizing specific binding such as binding between an antigen and an antibody, together with redox reaction for... | 06/25/2002 |
| 6287785 | Homogenous enzyme immunoassay process An improved homogeneous enzyme immunoassay process for quantitatively analyzing an antigen by determining the change in the enzymatic activity caused by a reaction between the antigen and an enzyme-labeled antibody. The antigen is reacted with an enzyme-l... | 09/11/2001 |
| 6190916 | Troponin I composition The present invention relates to stable compositions useful as primary standards and calibrators and controls comprising a cardiac troponin I (cTnI) such as native, recombinant, addition and deletion forms thereof, whether or not complexed with other trop... | 02/20/2001 |
| 6060285 | Process for the production of hetero-bispecific antibodies For the production of hetero-bispecific monoclonal antibodies at least the genes for the light chain and for the variable part of the heavy chain are isolated from a hybridoma cell line which secretes an antibody with a desired specificity and they are in... | 05/09/2000 |
| 5998155 | Stable composition of immobilized protein having affinity for biotin Compositions and methods for avidin or protein having affinity for biotin immobilized on an inert support material, e.g., agarose, are disclosed. The compositions have high activity levels for binding biotin and may include a bulking agent, e.g., maltose,... | 12/07/1999 |
| 5925533 | Tropinin I calibrator and method of use thereof in a sandwich immunoassay A conjugate consisting of a sequence of the analyte and an antibody against one of the antibodies used in the test can be employed, in aqueous solution and in precisely known quantity, as a stable calibrator in a sandwich immunoassay for detecting the ana... | 07/20/1999 |
| 5895811 | Artificial positive controls derived from bifunctional conjugates The invention relates to an artificial positive control reagents based on antibody conjugates that are used in immunochemical detection methods and to processes for the preparation of these reagents.... | 04/20/1999 |
| 5876947 | Monospecific antibody reactive with Fibrinogen and fibrinopeptide B The invention provides monospecific antibodies that are specifically reactive with fibrinopeptide B (FPB) and with fibrinogen and fragments thereof containing the amino acid sequence defined by SEQ ID NO:1. The invention also provides anti-FPB probes, inc... | 03/02/1999 |
| 5843690 | Immunoassay and kit for in vitro detection of soluble DesAABB fibrin polymers An in vitro immunoassay to detect and quantitate soluble crosslinked and non-crosslinked DesAABB fibrin polymers in a sample from a subject. The assay can be used to support a diagnosis of, to evaluate, and to monitor, in a mammalian subject, a thrombotic... | 12/01/1998 |
| 5811525 | Therapeutic and diagnostic methods using total leukocyte surface antigens The invention relates to the measurement of total leukocyte antigens, or fragments thereof, and the use of such measurements to enumerate cells, especially in whole blood. The term "total" leukocyte antigen used herein refers to the total amount of a leuk... | 09/22/1998 |
| 5723304 | Immunological detection using two detectable labels The invention relates to a method of detection, a sensor and a test-kit which find application in immunological detection (e.g., immunoassay). The invention provides, inter alia, a method of detection, suitable for use in immunological detection of an ent... | 03/03/1998 |
| 5714149 | Crosslinked antibodies and processes for their preparation Cross-linked antibody conjugates are described which have at least one interchain bridge containing a reporter or effector molecule. The bridge may be the residue of a homo-or heterofunctional cross-linking reagent, and is located away from the antigen bi... | 02/03/1998 |
| 5648237 | Expression of functional antibody fragments Methods for the high yield production of antibody Fv-containing polypeptides, especially Fab' and F(ab')2 antibody fragments are provided. Expression of heavy and light chain Fv in a microbial secretory system is followed by recovery of Fv from... | 07/15/1997 |
| 5583003 | Agglutination assay The assay off the present Invention is of particular use for detecting drugs, hormones, steroids, antibodies and other molecules circulating in the blood of a mammal or other animal.... | 12/10/1996 |
| 5573920 | Antibodies, and methods for their use This invention relates to antibodies and is particularly, though not exclusively, concerned with diagnostic and therapeutic methods using monoclonal bi- or tri-specific antibodies. The invention also provides a method in which binding of a first antigen t... | 11/12/1996 |
| 5491218 | Artificial positive controls derived from bifunctional conjugates The invention relates to artificial positive control reagents based on antibody conjugates that are used in immunochemical detection methods and to processes for the preparation of these reagents.... | 02/13/1996 |
| 5478753 | Positive calibrator/control composition for an IgM serology assay and an IgM serology assay There is described a positive calibrator/control composition for use in assays for the detection of antibodies to infectious disease agents. The composition includes a composite antibody of a nonspecific IgM immunoglobulin moiety covalently linked to a sp... | 12/26/1995 |
| 5447846 | Homogeneous Immunoassay process using covalent conjugate of enzyme and plural monoclonal antibodies for different epitopes on analyte An enzyme-labelled antibody adapted for use in a homogeneous immunoassay is provided. The enzyme-labelled antibody is a conjugate of an enzyme with two or more different monoclonal antibodies, each of the monoclonal antibodies being capable of specificall... | 09/05/1995 |
| 5415998 | Enzyme-containing quaternary immunocomplex homogeneous assay The invention concerns a method of homogeneous immunoassay of a ligand in a liquid test sample which comprises: a)incubating a mixture of (1) the liquid test sample; (1i) where the ligand under assay has only one epitope, a covalent conjugate of the ligan... | 05/16/1995 |
| 5273743 | Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent The present invention has multiple aspects. In its first aspect the present invention is directed to a trifunctional antibody-like compound that has tissue, organ, cell or molecule specificity and which is capable of being bifunctional when immobilized, v... | 12/28/1993 |
| 5242804 | Simultaneous dual analyte assay A simultaneous dual analyte assay for determining the fertile period of the human menstrual cycle. The assay utilizes a capture reaction component consisting of P-3-G immobilized on a microporous membrane, a blocking reaction component consisting of anti ... | 09/07/1993 |
| 5188942 | Method for determining bluetongue virus antibodies in serum A rapid, competitive enzyme linked immunosorbent assay (cELISA) for the determination of Bluetongue virus antibodies in serum is described. This method utilizes either a biotinylated monoclonal antibody to Bluetongue virus and streptavadin-enzyme in conju... | 02/23/1993 |
| 5185433 | Cross-linking protein compositions having two or more identical binding sites The present invention provides cross-linked protein compositions consisting of two or more units of a target-specific protein joined by binding sulfhydryl groups on the target-specific protein units to a sulfhydryl-selective cross-linking agent and a meth... | 02/09/1993 |
| 5173294 | DNA probe for the identification of Haemophilus influenzae A plasmid which contains a genetic code for an immunogenic portion which is conserved in many strains of nontypable Haemophilus influenzae and the bacterium containing this plasmid is disclosed. The immunogenic portion is preferably an epitope on an outer... | 12/22/1992 |
| 5164311 | Preparation of an antibody-enzyme conjugate An antibody-enzyme conjugate is prepared having an enzyme to antibody ratio of approximately 3. The conjugate is produced by adding sulfhydryl groups to an antibody and maleimidyl groups to an enzyme to produce a modified antibody and enzyme, and reacting... | 11/17/1992 |
| 5141736 | Bispecific monoclonal antibody, its production and use The present invention discloses, a bispecific monoclonal antibody to an ansamitocin derivative and a target antigen, particularly tumor-associated antigen, which can carry an anasamitocin derivative in a stable and inactive form at other sites than the ta... | 08/25/1992 |
| 5130234 | Method of quantitative determination utilizing enzyme aggregation A quantitative determination of a substance is performed in a homogeneous system based on a change in enzyme activity; differences between the activity of a free enzyme and that of an enzyme bound by an aggregation or chemical bonding are observed. A pero... | 07/14/1992 |
| 5126442 | Advanced glycosylation endproducts and associated methods New and useful chromophores have been isolated from the reaction mixture of proteins exposed to reducing sugars in the presence of sulfite over time. The chromophores are believed to be intermediates in nonenzymatic polypeptide glycosylation. The measurem... | 06/30/1992 |
