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Class 435/97 - Produced by the action of a glycosyl transferase (e.g., alpha, beta, gamma-cyclodextrins by the action of glycosyl transferase on starch, etc.)


Subclass of Class 435 - Chemistry: molecular biology and microbiology
Definition: Processes wherein the product synthesized is produced by
No. of patents: 278
Last issue date: 01/03/2012


1              
NumberTitleIssue Date
8088604Production of defined monodisperse heparosan polymers and unnatural polymers with polysaccharide synthases
The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate or chondroitin or heparin/heparosan synthases from Pasteurella, in order to create a variety of glyco...
01/03/2012
8084236Compositions and methods for modifying cell surface glycans
Methods and compositions for modifying glycans (e.g., glycans expressed on the surface of live cells or cell particles) are provided herein. ...
12/27/2011
7960148Glucanases, nucleic acids encoding them and methods for making and using them
The invention relates to polypeptides having glucanase, e.g., endoglucanase, mannanase, xylanase activity or a combination of these activities, and polynucleotides encoding them. In one aspect, the glucanase activity is an endoglucanase activity (e.g., endo-1,4-beta...
06/14/2011
7883873Saccharide composition synthesizer
The present invention provides a sugar chain synthesizer capable of continuously reacting sugar chains when a plurality of sugar chains are successively reacted. The sugar chain synthesizer of the present invention includes a plurality of vessels containing respecti...
02/08/2011
7879766Method of preparing a sugar chain library and use thereof
The present invention provides methods which enables synthesis of various sugar chains and products obtained by the same. More specifically, the present invention provides protected sugar chain compounds represented by the formula (I) below:
02/01/2011
7846697Method of producing a low molecular weight organic compound in a cell
A method of producing a low molecular weight organic compound (e.g. a plant or bacteria secondary metabolite) in increased yields involving use of a microorganism cell, which comprises a gene involved in the biosynthesis pathway leading to a low molecular weight org...
12/07/2010
7723080Murine α (1,3) fucosyltransferase Fuc-TVII, DNA encoding the same, method for preparing the same, antibodies recognizing the same, immunoassays for detecting the same, plasmids containing such DNA, and cells containing such a plasmid
A gene which encodes a murine leukocyte α(1,3)fucosyltransferase capable of synthesizing the sialyl Lewis x determinant has been cloned. ...
05/25/2010
7718404α-isomaltosylglucosaccharide-forming enzyme, process and uses of the same
The object of the present invention is to provide an α-isomaltosylglucosaccharide-forming enzyme, process of the same, cyclotetrasaccharide, and saccharide composition comprising the saccharide which are obtainable by using the enzyme; and is solved by establishing...
05/18/2010
7709234α-1,3-fucosyltransferase
The invention provides a novel species of α-1,3-fucosyltransferase expressed by a gene cloned from animal cells, a cDNA coding for the α-1,3-fucosyltransferase, a method of detecting, or inhibiting the production of, the α-1,3-fucosyltransferase which involves th...
05/04/2010
7678555Production of crystalline short chain amylose
A process for producing a starch comprises treating a feed starch that comprises amylopectin with glucanotransferase to produce a chain-extended starch, and treating the chain-extended starch with a debranching enzyme to produce a starch product that comprises amylo...
03/16/2010
7666632Nucleic acid molecules encoding alternansucrase
Nucleic acid molecules encoding an alternansucrase are provided. Moreover, vectors, host cells and plant cells transformed by the herein-described nucleic acid molecules and plants containing them are provided. Furthermore, methods are described for preparing transg...
02/23/2010
7588922Nucleic acid molecules encoding enzymes having fructosyltransferase activity, and their use
Nucleic acid molecules are described which encode polypeptides having the enzymatic activity of a fructosyltransferase. Also, vectors, host cells and transgenic plants are described which contain such nucleic acid molecules. Furthermore, processes for producing poly...
09/15/2009
7579173Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using the same
The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate or chondroitin or heparin/heparosan synthases from Pasteurella, in order to create a variety of glyco...
08/25/2009
7575904Polymer grafting by polysaccharide synthases
The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate synthase from Pasteurella multocida. The present invention also relates to coatings for biomaterials ...
08/18/2009
7527949Polysaccharides of
The invention is directed to immunogenic compositions comprising polysaccharides and polysaccharide-protein conjugates that are useful to induce or detect the production of antibodies specific for H. pylori. The invention is also directed to methods of purify...
05/05/2009
7524655Synthesis of oligosaccharides, glycolipids, and glycoproteins using bacterial glycosyltransferases
This invention provides nucleic acid and amino acid sequences of fucosyltransferases from Helicobactor pylori. The invention also provides methods to use the fucosyltransferases to synthesize oligosaccharides, glycoproteins, and glycolipids. ...
04/28/2009
7455996Soybean raffinose synthase and a method for producing raffinose
Raffinose is produced by allowing a raffinose synthase having the following properties to act on sucrose and galactinol: (1) action and substrate specificity: produces raffinose from sucrose and galactinol; (2) opt...
11/25/2008
7396666Glycosyltransferase, nucleic acid encoding the glycosyltransferase and method of testing canceration using the nucleic acid
A tumor marker nucleic acid of the present invention is concerned with a nucleic acid hybridizing under stringent conditions to a nucleotide sequence described in SEQ ID NO: 1 or a complementary nucleotide sequence thereof. A method of testing canceration of the pre...
07/08/2008
7361644Specific antagonist for both E- and P-selectins
Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-med...
04/22/2008
7342094Tumor vaccines for MUC1-positive carcinomas
Tumor vaccines for the use against MUC1 positive carcinomas are presented. A tumor vaccine containing synthetic peptides comprising sequences of the human epithelial mucin MUC1 containing the immunodominat region PDTRPAP which is glycosylated at the threonine. Prefe...
03/11/2008
7338940Cancer treatment including glycolytic inhibitors
Glycolytic inhibitors are useful in the treatment of solid tumors by attacking anaerobic cells at the center on the tumor. 2-deoxyglucose, oxamate and various analogs thereof are identified as having a natural selective toxicity toward anaerobic cells, and will sign...
03/04/2008
7335500Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose
This invention contemplates improved methods of enzymatic production of carbohydrates especially fucosylated carbohydrates. Improved syntheses of glycosyl 1- or 2-phosphates using both chemical and enzymatic means are also contemplated. The phosphorylated glycosides...
02/26/2008
7326770fucosyltransferases
This invention provides nucleic acid and amino acid sequences of fucosyltransferases from Helicobactor pylori. The invention also provides methods to use the fucosyltransferases to synthesize oligosaccharides, glycoproteins, and glycolipids. ...
02/05/2008
7309587Process for producing β 1,3-N-acetylglucosaminyl-transferase and N-acetylglucosamine-containing complex carbohydrate
The present invention can provide a process for producing a protein having β1,3-N-acetylglucosaminyltransferase activity using a transformant comprising a DNA encoding a protein having β1,3-N-acetylglucosaminyltransferase activity derived from a microorganism belo...
12/18/2007
7309600sialyltransferase and methods of use thereof
The present invention is directed to sialytransferases, such as SiaA sialytransferases isolated from Haemophilus influenzae. Further provided herein are methods for producing sialylated lipooligosaccharides, vaccines, and host cells and systems for the produc...
12/18/2007
7304148Sugar chain asparagine derivatives, sugar chain asparagine, sugar chain, and processes for producing these
An asparagine-linked α2,3-oligosaccharide having undeca- to hepta-saccharides, an asparagine-linked α2,6-oligosaccharide having undeca- to hepta-saccharides and containing fluorine and an asparagine-linked oligosaccharide derivative containing at least one fucose ...
12/04/2007
7291607Isomaltooligosaccharides from as neutraceuticals
Isomaltooligosaccharides (IMOs) produced by Leuconostoc mesenteroides ATCC 13146 fermentation with a sucrose:maltose ratio of 2:1 have been discovered to be effective prebiotics in mixed cultures of microbial populations, including cultures from chicken ceca....
11/06/2007
7264962Enzymatic cascade bioreactor
Disclosed is an apparatus and method for continuously converting sucrose to β-D-glucose. The method comprises a three stage enzymatic reactor in which an aqueous solution of sucrose is first converted into a solution of fructose and α-D-glucose by passing it throu...
09/04/2007
7259239Lipopolysaccharide α-2,3 sialyltransferase of and its uses
The structure and specificity of a recombinant α2,3-sialyltransferase from Campylobacter spp., is disclosed. Also provided are methods for using the α2,3-sialyltransferase in the production of desired carbohydrate structures and nucleic acids that encode th...
08/21/2007
7256029Biopolymer thickener
A novel strain of Lactococcus lactis subspecies cremori (“Ropy 352”) has been identified and isolated. Ropy 352 produces a previously unknown exopolysaccharide (EPS 352) that when expressed or added to milk, imparts highly desirable sensory charact...
08/14/2007
7247456Preparation of fucosylated oligosaccharides
This invention provides methods for practical enzymatic conversion of GDP-mannose to GDP-fucose. These methods are useful for efficient synthesis of reactants used in the synthesis of fucosylated oligosaccharides. ...
07/24/2007
7247770Regulating metabolism by modifying the level of trehalose-6-phosphate
Method for the inhibition of carbon flow in the glycolytic direction in a cell by increasing the intracellular availability of trehalose-6-phosphate. ...
07/24/2007
7244601Fusion proteins for use in enzymatic synthesis of oligosaccharides
This invention provides fusion polypeptides that include a glycosyltransferase catalytic domain and a catalytic domain from an accessory enzyme that is involved in making a substrate for a glycosyltransferase reaction. Nucleic acids that encode the fusion polypeptid...
07/17/2007
7241607Microorganism producing fructosyl transferase and method for producing fructooligosaccharides and neofructooligosaccharides using the same
The present invention relates to a novel microorganism and a method for producing fructooligosaccharides and neofructooligosaccharides. More particularly, the present invention relates to Penicillium citrinum KCTC 10225BP of soil origin which produces fructos...
07/10/2007
7241605Polypeptide
According to the present invention, there can be provided a novel polypeptide having β1,3-galactosyltransferase activity involved in the synthesis of type 1 sugar chains, a DNA coding for said polypeptide, a recombinant vector comprising said DNA, a transformant ca...
07/10/2007
7223570Branched cyclic tetrasaccharide, process for producing the same, and use
The object of the present invention is to provide a novel glycosyl derivative of cyclotetrasaccharide represented by cyclo{→6)-α-D-glucopyranosyl-(1→3)-α-D-glucopyranosyl-(1→6)-α-D-glucopyranosyl-(1→3)-α-D-glucopyranosyl-(1→}, and it is solved by provi...
05/29/2007
7223571Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same
The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate or chondroitin or heparin/heparosan synthases from Pasteurella, in order to create a variety of glyco...
05/29/2007
7220555Practical sialylation of recombinant glycoproteins
This invention provides methods for practical in vitro sialylation of glycoproteins, including recombinantly produced glycoproteins. The methods are useful for large-scale modification of sialylation patterns. ...
05/22/2007
7211663Synthesis of oligosaccharides, reagents and methods related thereto
One aspect of the present invention relates to differentially protected glycosyl phosphates. Another aspect of the present invention relates to the preparation of glycosyl phosphates from glycal precursors. In another aspect of the present invention, glycosyl phosph...
05/01/2007
7208307Preparation of acariogenic sugar substitutes
The invention relates to sucrose isomerases, to DNA sequences that code for sucrose isomerases, and to novel processes for the production of non-cariogenic sugars. ...
04/24/2007
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