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| Number | Title | Issue Date |
| 7329536 | Piezoimmunosensor An apparatus comprising one or more piezoelectric mass sensors for use in diagnostic and analytic processes, in particular for immunochemical detection of diagnostically relevant analytes in real time, is described. Each piezoelectric mass sensor comprises a piezoel... | 02/12/2008 |
| 7326578 | Urine assay for ovarian reserve It has been found that a urine test for ovarian reserve can be provided which is equivalent in sensitivity to current laboratory methods which determine ovarian reserve based on FSH levels in serum. A lateral flow device for indicating ovarian reserve is disclosed. ... | 02/05/2008 |
| 7314763 | Fluidics-based assay devices A fluidics-based assay device for detecting the presence or quantity of an analyte residing in a test sample is provided. The device utilizes a self-calibrated magnetic binding assay format (e.g., sandwich, competitive, etc.) that includes detection probes capable o... | 01/01/2008 |
| 7297554 | Immunoassay system A competitive immunoassay, dye and method for rapidly detecting the presence of one or more target ligands within a fluid sample suspected of containing such ligand or ligands. The immunoassay comprises a protein-binding membrane, a first absorbent pad, a second abs... | 11/20/2007 |
| 7267992 | Method for the determination of an analyte in a liquid A method is provided to determine the presence of an analyte in a sample. The method provides an element with a sample application zone, a detection zone, a zone containing immobilized analyte or analyte analogue, a conjugate that has a first bioaffine binding partn... | 09/11/2007 |
| RE39816 | Conjunctive analysis of biological marker expression for predicting cardiac mortality A diagnostic tool is disclosed for accurately and rapidly diagnosing the condition of an ailing organ. Although applicable to numerous organ and organ systems, this application particularly illustrates the concept of conjunctive marker utilization as it relates to d... | 09/04/2007 |
| RE39664 | Lateral flow chromatographic binding assay device The present invention relates to improved specific binding assay devices comprising a chromatographic medium including a reaction site at which a specific binding reagent is immobilized, a sample application well located adjacent to the chromatographic medium and of... | 05/29/2007 |
| 7179660 | Carriers coated with polysaccharides, their preparation and use A polysaccharide coated carrier having a coating of at least two successive layers of polysaccharide. The first polysaccharide layer spontaneously associates with a second polysaccharide layer and, optionally, the carrier. Each successive layer of polysaccharide spo... | 02/20/2007 |
| 7144742 | Quantitative lateral flow assays and devices This invention provides solid phase specific binding lateral flow assay methods, devices and kits for quantitating high and low molecular weight analytes. The methods and devices of the invention employ labelled reagents which are either analyte analogs or complemen... | 12/05/2006 |
| 7026002 | Element, method and kit for the determination of an analyte in a liquid The invention concerns an element for the determination of an analyte in a liquid by means of a specific binding reaction of two bioaffine binding partners containing in or on material which enables liquid transport between the zones. The element comprises a sample ... | 04/11/2006 |
| 6951760 | Diagnostic neodymium(III), ytterbium(III), or erbium(III) ion-ligand complexes The invention relates to a method for detection of an analyte in a test sample by a specific binding reaction among the analyte, a specific binding partner for the analyte, and an (immuno)reactant provided with a label, characterized in that the label is a lanthanid... | 10/04/2005 |
| 6951763 | Detection of antibodies to glycosphingolipids using solid-phase reactants coated with carbonyl groups Methods of detecting antibodies to one or more glycosphingolipid(s) of interest in a sample are disclosed which comprise using a solid-phase reactant having carbonyl groups attached theron, and the glycosphingolipid(s) of interest linked to the solid-phase reactant ... | 10/04/2005 |
| 6924153 | Quantitative lateral flow assays and devices This invention provides solid phase specific binding lateral flow assay methods, devices and kits for quantitating high and low molecular weight analytes. The methods and devices of the invention employ labelled reagents which are either analyte analogs or complemen... | 08/02/2005 |
| 6913935 | Multiple assay method A method for the assay of N samples each containing a compound to be tested, comprises providing N reaction vessels each containing a population of carrier beads and other reagents for performing the assay, where N is at least 2 e.g. 80-4000. Each population of carr... | 07/05/2005 |
| 6884628 | Multifunctional polymeric surface coatings in analytic and sensor devices Multifunctional, polyionic copolymers with molecular architectures and properties optimized for specific applications are synthesized on/or applied to substrate surfaces for analytical and sensing purposes. The coatings are particularly useful for suppression of non... | 04/26/2005 |
| 6884597 | Method for detecting acetyltransferase and deacetylase activities and method for screening inhibitors or enhancers of these enzymes A method for simply and conveniently detecting acetyltransferase and deacetylase activities of proteins by executing an acetylation reaction of a peptide substrate with an acetyltransferase, or a deacetylation reaction of an acetylated peptide substrate with a deace... | 04/26/2005 |
| RE38688 | Sheet-like diagnostic device A solid diagnostic device for the quantitative determination of substances of biological affinity in biological fluids is described. A process is also described in which the biological fluid is brought into contact with a specific functional sector of the device, th... | 01/18/2005 |
| 6818455 | Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents An analytical test device useful for example in pregnancy testing, comprises a hollow casing (500) constructed of moisture-impervious solid material, such as; plastics materials, containing a dry porous carrier (510) which communicates indirectly with ... | 11/16/2004 |
| 6723516 | Method for continuously detecting the presence and quantity of analytes in a flowing liquid stream A method is provided for continuously monitoring for the presence or quantity of an analyte in a flowing liquid stream. The method involves binding an analyte-specific receptor species to the surface of a piezoelectric substrate, contacting the surface bound recepto... | 04/20/2004 |
| 6686208 | Device and method for carrying out fluoresence immunotests The invention relates to devices and methods for carrying out quantitative fluorescence immunoassays using evanescent field excitation. Light from at least one light source is directed onto the boundary between two media which have differing refractive in... | 02/03/2004 |
| 6670198 | Test piece and system for reading out image information from the test piece A test piece for use in biological analyses includes a plurality of different known specific binding substances disposed in predetermined positions on a substrate. The specific binding substances are disposed on a plurality of surfaces provided by the sub... | 12/30/2003 |
| 6638728 | Coated surfaces with high capacity for capturing target molecules New protein coated surfaces, which have a high capacity for capturing target molecules, thus yielding assays with enhanced sensitivity, are disclosed. Surfaces prepared according to the present invention contain a coating consisting essentially of strepta... | 10/28/2003 |
| 6534270 | Biochip and method for fabricating the same Disclosed are biochips having a high detecting sensitivity with readiness in fabrication of microarray, and a method for fabricating the same, in which a solid support wound with fibers is immersed in a solution containing biomolecules to immobilize the b... | 03/18/2003 |
| 6531323 | Agglutination assay method and element in a dry system An agglutination assay method for quantitatively determination of an analyte in a liquid sample using particles bearing an anti-analyte. A non-fluid substance which retains the particles while suppressing the diffusion of the particles therein is used as ... | 03/11/2003 |
| 6521465 | Parallel production of high density arrays An array bundle is provided for creating multiple arrays for testing. The array bundle is adapted to be cut transversely to form a series of identical arrays of cells. In one embodiment, the array bundle is used in detecting predetermined components from ... | 02/18/2003 |
| 6511798 | Methods for the preparation of cell monolayers Cell based screens for studying drug transport are described and improved methods for the preparation of cell monolayers for use in such screens are disclosed.... | 01/28/2003 |
| 6492119 | Hard macro array A macro array comprises a film-shaped hard porous body and a plurality of spots, which contain test substances and are arrayed on the film-shaped hard porous body. The film-shaped hard porous body may be constituted of a surface layer region, which is pro... | 12/10/2002 |
| 6461828 | Conjunctive analysis of biological marker expression for diagnosing organ failure A diagnostic tool is disclosed for accurately and rapidly diagnosing the condition of an ailing organ. Although applicable to numerous organ and organ systems, this application particularly illustrates the concept of conjunctive marker utilization as it r... | 10/08/2002 |
| 6458601 | Test piece and system for reading out image information from the test piece A test piece for use in biological analyses includes a plurality of different known specific binding substances disposed in predetermined positions on a substrate. The specific binding substances are disposed on a plurality of surfaces provided by the sub... | 10/01/2002 |
| 6458548 | Containers and kits for the determination of cell functions, and method for the determination thereof A container for measurement of cell functions, for use in the determination of a physiologically active substance produced by blood cells, is constituted such that an amount of material capable of inducing production of the physiologically active substanc... | 10/01/2002 |
| 6429026 | One-step all-in-one dry reagent immunoassay The invention relates to a novel competitive or non-competitive immunoassay comprising the steps of immobilizing an assay specific component on a solid phase in a reaction well, adding a labelled assay specific component, drying said components, adding the sam... | 08/06/2002 |
| 6376195 | Indirect label assay device for detecting small molecules and method of use thereof A chromatographic strip positive readout binding assay device and method suitable for quick, sensitive and reliable field testing for small molecules such as environmental contaminants, drugs of abuse, therapeutic drugs and hormones. The detectable label ... | 04/23/2002 |
| 6372515 | Device for the testing of fluid samples and process for making the device A test card for drugs of abuse has a thin flat member having the size and shape of a business card. A plurality of immunoassay test strips extend longitudinally from top to bottom at the card and are fastened side by side in parallel on one or both sides ... | 04/16/2002 |
| 6350620 | Method for producing micro-carrier and test method by using said micro-carrier The invention provides a method for producing a micro-carrier, which includes patterning pluralities of bar code on a mask; exposing the bar code to a substrate coated with photoresist; etching and removing residual photoresist and electroforming to a nic... | 02/26/2002 |
| 6326214 | Immunity testing device An immunity testing device formed of a thin sheet of material folded to three portions, and the two end portions; named "front cover"0 and "back cover"; fold back to different sides of the center part; named base seat; to provide protection on both sides ... | 12/04/2001 |
| 6306664 | Parallel production of high density arrays A method to produce arrays of compounds for concurrent testing is described. Two formats are described using porous rods or porous sheet materials. In one format, the compounds of the array are immobilized onto porous rod elements. In the second format, t... | 10/23/2001 |
| 6287785 | Homogenous enzyme immunoassay process An improved homogeneous enzyme immunoassay process for quantitatively analyzing an antigen by determining the change in the enzymatic activity caused by a reaction between the antigen and an enzyme-labeled antibody. The antigen is reacted with an enzyme-l... | 09/11/2001 |
| 6277652 | Colorimetric sensor employing polydiacetylene membrane Disclosed is a colorimetric sensor comprising polydiacetylene membrane liposomes, a polydiacetylene membrane film or fine particles coated with a polydiacetylene membrane, in which the polydiacetylene membrane is incorporated with a protein having a reduc... | 08/21/2001 |
| 6270983 | Surfaces coated with streptavidin/avidin The invention relates to surfaces coated with streptavidin and avidin for use in immunoassays, wherein the surfaces comprise a layer of streptavidin and avidin which are bonded on a surface of a solid supporting material through a biotinylated adhering ag... | 08/07/2001 |
| 6261776 | Nucleic acid arrays A method and apparatus for preparation of a substrate containing a plurality of sequences. Photoremovable groups are attached to a surface of a substrate. Selected regions of the substrate are exposed to light so as to activate the selected areas. A monom... | 07/17/2001 |
