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A self defense weapon formed as a memo pad and which is easily held by a person's fingers, therefore making it possible to provide protection from a mugger and also to quickly and easily write a record or a message without failure of missing or forgetting significant information under a stressful situation.
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| Number | Title | Issue Date |
| 7138237 | Diagnosis, prevention and treatment of Crohn's disease using the OmpC antigen The present invention provides a method of diagnosing Crohn's disease in a subject by determining the presence or absence of IgA anti-OmpC antibodies in the subject, where the presence of the IgA anti-OmpC antibodies indicates that the subject has Crohn's disease. | 11/21/2006 |
| 6939748 | Nano-size semiconductor component and method of making A method is disclosed for making a nano-size semiconductor component within a wide-bandgap semiconductor substrate. A first thermal energy beam is directed onto a first portion of the wide-bandgap semiconductor substrate to change the structure of the wide-bandgap s... | 09/06/2005 |
| 6932969 | Ig fractions having immunomodulatory activity The invention concerns a method for preparing Ig fractions from human polyvalent intravenous Immunoglobulins (IV Ig) which are in particular likely to be responsible for the immunomodulatory effect observed during the treatment of certain autoimmune diseases. The in... | 08/23/2005 |
| 6838250 | Immunoassay for C-reactive protein The present invention relates to new CRP immunoassay compositions. The compositions include a low affinity anti-human CRP monoclonal antibody, and an antiidiotypic antibody raised against it. The invention further provides a method for obtaining antiidiotypic monocl... | 01/04/2005 |
| 6645732 | Antigen-specific IgG detection The invention concerns a method for the determination of antigen-specific antibodies of the immunoglobulin G class in the presence of immunoglobulins of the M class in body fluids by incubation with at least two different receptors R1 and R | 11/11/2003 |
| 6537760 | Receptor binding assay for detecting TSH-receptor auto-antibodies In a competitive receptor binding assay for detecting TSH-receptor auto-antibodies in a biological sample, the sample is reacted in a reaction mixture which contains (i) a TSH-receptor or TSH-receptor preparation; (ii) a primary competitor, for example la... | 03/25/2003 |
| 6482648 | Stable troponin preparation and the use thereof as a calibrator/control in immunoassays The present invention relates to methods for the production of a stable troponin preparation and its use as a calibrator and/or control in immunoassays. The formulation is prepared from mammalian, preferably bovine, heart tissue which provides a calibrato... | 11/19/2002 |
| 6413721 | Methods of isolating common and specific antigens from excretory-secretory products of protostrongylidae Novel Protostrongylidea antigens and early and accurate diagnostic methods for Protostrongylidae infection are disclosed. Novel P. tenuis-specific antigens and methods of discriminating between P. tenuis infection and infection with other closely-related ... | 07/02/2002 |
| 6040134 | Method of diagnosing preclinical diabetes The present invention relates to a method of diagnosing preclinical insulin-dependent diabetes mellitus by determining the T cell response to a specific islet cell antigen fetal antigen 1 (FA1) or the presence of autoantibodies against FA1 in serum, a tes... | 03/21/2000 |
| 5965378 | Antibody class-specific interference eliminating reagent The invention concerns a composition composed of several different antibodies or/and antibody fragments which is suitable as a reagent to reduce interferences in an immunological method for the class-specific detection of antibodies from one or several of... | 10/12/1999 |
| 5837460 | Methods of identifying biologically active receptor-binding peptides A method of identifying peptides which mimic biologically active proteins is disclosed. The method comprises the steps of making a recombinant antibody library from genetic material obtained from an animal which has been immunized against antibodies that ... | 11/17/1998 |
| 5824506 | Dengue virus peptides and methods Peptide antigens derived from the dengue virus type-2 glycoprotein NS1 are provided. The peptide antigens are specifically immunoreactive with sera from individuals infected with the dengue virus. The antigens are useful as diagnostic tools in determining... | 10/20/1998 |
| 5716793 | Method for diagnosing a patient for chlamydia A method of detecting chlamydia in a extracellular sample is provided which comprises contacting the sample with an idiotypic antibody to GLXA to form an immunocomplex and detecting the immunocomplex.... | 02/10/1998 |
| 5691151 | Methods of screening for ulcerative colitis and crohn's disease by detecting VH3-15 autoantibody and panca The present invention provides novel methods of screening for ulcerative colitis and Crohn's disease which include the detection of two disparate autoantibodies: pANCA and VH3-15 autoantibody. The present invention also provides kits for screening ulcerat... | 11/25/1997 |
| 5681700 | Assay for pathogenicity of anti-DNA antibodies Assays that are prognostic for patients that will develop nephritis have been developed where patient serum is screened for the presence of anti-dsDNA antibodies that are cross reactive with A and D SnRNP proteins. The assays are based on the use of eithe... | 10/28/1997 |
| 5641690 | Method of determining haptens, use of method and components useful in method A method is described for determining a hapten which method comprises (i) contacting the hapten with a binding partner of the hapten, whereby the hapten becomes bound to some of the binding partner, (ii) contacting the unbound binding partner with a secon... | 06/24/1997 |
| 5512435 | Receptor-binding antiproliferative peptides Methods and composition are provided for identifying antiproliferative polypeptides which inhibit clonal expansion and/or induce apoptosis in cells of a predetermined cell population (e.g., a neoplastic cell sample) expressing a cell surface receptor whic... | 04/30/1996 |
| 5493009 | Antiidiotypic monoclonal antibodies MK2-23 anti-melanomal antibody 763.74 The invention concerns murine antiidiotypic monoclonal antibodies which are the internal image of determinants recognized by a monoclonal antibody on high molecular weight-melanoma associated antigen (HMW-MAA), antibody derivatives, hybridoma cell lines s... | 02/20/1996 |
| 5468651 | Method for determining haptens, use of method and components useful in method A method is described for determining a hapten which method comprises (i) contacting the hapten with a binding partner of the hapten, whereby the hapten becomes bound to some of the binding partner, (ii) contacting the unbound binding partner with a secon... | 11/21/1995 |
| 5401636 | Enhanced sensitivity agglutination assays multivalent ligands An agglutination-based method for detecting and/or an analyte by allowing the agglutination reaction between the analyte, a carrier reagent, and an agglutinating agent to occur in the presence of a multivalent ligand.... | 03/28/1995 |
| 5124249 | Method for evaluating protection to bee venom Venom immunotherapy is a highly effective treatment for bee sting sensitive individuals. Treated individuals and those naturally exposed to repeated bee stings, such as beekeepers have been shown to develop anti bee venom anti-idiotypic antibodies. These ... | 06/23/1992 |
| 5118611 | Adenocarcinoma antigen binding methods and reagents Novel adenocarcinoma binding human monoclonal antibody binds preferentially with ADCA antigens and is useful in diagnostic and imaging methods for identifying and locating adenocarcinoma cells, and in therapeutic methods to reduce the reproduction of aden... | 06/02/1992 |
| 5114844 | Diagnosis and treatment of insulin dependent diabetes mellitus A 65 KD heat shock protein, proteins cross-reactive therewith, or antibodies thereto can be used for detecting in humans the existence of, a tendency to develop, or the initiation of a process leading to insulin dependent diabetes mellitus. Antibodies to ... | 05/19/1992 |
| 5096807 | Imaging immunoassay detection system with background compensation and its use The invention provides an imaging immunoassay detection apparatus system and method capable of detecting multiple light emitting reactions from small volume samples simultaneously and quantifying the same.... | 03/17/1992 |
| 5068177 | Anti-idiotype antibodies induced by synthetic polypeptides Chemically synthesized polypeptides containing about 6 to 40 amino acid residues and having amino acid residue sequences that substantially correspond to the primary amino acid residue sequences of particular variable or hypervariable regions of immunoglo... | 11/26/1991 |
| 4960712 | System and method for complement pathway analysis The present invention relates to systems and methods used to assay for particular complement component fragments. The invention can be used to determine the amount of a particular complement component fragment in a sample. The fragment can be fluid phase ... | 10/02/1990 |
| 4845026 | Assay systems for detecting cell-free T cell antigen receptor related molecules and the clinical utilities of the assays Methods are provided for detecting and determining the amount in a sample of an antigenic determinant from an antigen receptor derived and released from a T cell or NK cell. Methods are also provided for detecting and determining the amount in a sample of... | 07/04/1989 |
| 4828981 | Immunoassays for determining Dirofilaria immitis infection using antiidiotype monoclonal antibody reagents Competitive immunoassays, which employ idiotypic and antiidiotypic monoclonal antibody reagents, are described. These competitive immunoassays are particularly useful for the detection of low concentrations of analyte for which labeled reference analyte i... | 05/09/1989 |
| 4818684 | Auto-anti-idiotypic monoclonal antibodies to steroid receptors and uses thereof A competitive immunoassay for a steroid receptor has been developed in which monoclonal antibodies capable of binding to the steroid receptor are competitively bound by anti-steroid antibodies capable of binding to the steroid. The presence or amount of m... | 04/04/1989 |
| 4722890 | Quantitative assay for human terminal complement cascade activation The present invention discloses an enzyme-linked immunosorbent assay (ELISA) to quantitate fluid phase terminal complement activation. Upon activation to form C5b-9, terminal complement components express neoantigens not present in the unassembled individ... | 02/02/1988 |
| 4699880 | Method of producing monoclonal anti-idiotype antibody A method for determining the presence of an antigen in a liquid sample. The method includes incubating the sample with an antibody which specifically binds an epitope on the antigen in the presence of a given quantity of an anti-idiotype antibody which sp... | 10/13/1987 |
| 4661444 | Homogeneous immunoassays employing double antibody conjugates comprising anti-idiotype antibody Homogeneous immunoassays employing double ligand binding conjugates comprising an anti-idiotype binding partner. The anti-idiotype binding partner competes with ligand for an insolubilized ligand specific binding partner. Inhibition of binding of the conj... | 04/28/1987 |
| 4642284 | Method and system for detection of complement pathway activation A method and system for detecting and preferably measuring the presence of an activated complement complex in a sample is discussed. The presence of such an activated complex is indicative of complement pathway activation and includes a first complement c... | 02/10/1987 |
| 4591570 | Matrix of antibody-coated spots for determination of antigens This invention relates to a novel immunoassay device and method for the determination of antigenic substances. The device essentially comprises a pattern or array of minute antibody-coated spots on the surface of a support. The array of antibody-coated sp... | 05/27/1986 |
| 4536479 | Use of anti-idiotype antibodies in immunoassays The use of anti-idiotype antibodies as functional substitutes for antigens or haptens in immunoassays is disclosed.... | 08/20/1985 |
| 4514505 | Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays Mixtures of monoclonal antibodies which contain effective assaying amounts of each of at least two monoclonal antibodies that bind to different antigenic sites on the antigen and are capable under appropriate conditions of binding simultaneously to an ant... | 04/30/1985 |
| 4513088 | Assay for monoclonal antibody against surface Ig of a human B cell tumor An assay that facilitates screening of hybridoma culture media for monoclonal anti-idiotype antibodies, particularly murine monoclonal antibodies that are useful for treating human B cell tumors is disclosed. The assay is a solid phase type assay and invo... | 04/23/1985 |
