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Actor Marlon Brando has four patents, all named "Drumhead tensioning device and method."
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| Number | Title | Issue Date |
| 7442525 | Method for expressing HIV polypeptides Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare... | 10/28/2008 |
| 7408053 | Recombinant DNA constructs for GAG polypeptides and polypeptides produced thereby Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare... | 08/05/2008 |
| 7368277 | Method for assay of antibodies and antibody assay device The invention relates to a technology by which antibodies directed to sources of infection in body fluids can be assayed with high accuracy, expediency and specificity. More particularly, the invention provides an antibody immunoassay method in which the antigen-ant... | 05/06/2008 |
| 7205101 | Human immunodeficiency virus (HIV) nucleotide sequences, recombinant polypeptides, and applications thereof Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare... | 04/17/2007 |
| 7163818 | Bacteriophage having multiple host range The present invention discloses compositions and methods for the prophylaxis and treatment of bacterial infections by the use of polyvalent bacteriophage having multiple host range. ... | 01/16/2007 |
| 7129337 | Sequences of hepatitis C virus genotypes and their use as prophylactic, therapeutic and diagnostic agents The present invention relates to new genomic nucleotide sequences and amino acid sequences corresponding to the coding region of these genomes. The invention relates to new HCV types and subtypes sequences which are different from the known HCV types and subtypes se... | 10/31/2006 |
| 7014847 | Methods for preventing reovirus recognition for the treatment of cellular proliferative disorders The present invention pertains to methods for preventing reovirus recognition in the treatment of cellular proliferative disorders, and particularly ras-mediated cellular proliferative disorders, in mammals. The method comprises suppressing or otherwise inhibiting t... | 03/21/2006 |
| 6861212 | NANBV diagnostics and vaccines A family of cDNA sequences derived from hepatitis C virus (HCV) are provided. These sequences encode antigens which react immunologically with antibodies present in individuals with non-A non-B hepatitis (NANBH), but which are absent from individuals infected with h... | 03/01/2005 |
| 6803223 | Plant branched-chain amino acid biosynthetic enzymes This invention relates to an isolated nucleic acid fragment encoding a branched-chain biosynthetic enzyme. The invention also relates to the construction of a chimeric gene encoding all or a portion of the branched-chain biosynthetic enzyme, in sense or antisense or... | 10/12/2004 |
| 6664099 | Method for the preservation of viruses and mycoplasma A biologically-active material comprising a live virus or mycoplasma is preserved by a method of desiccation, without lyophilisation, in a matrix of glassy trehalose having a residual moisture content of not greater than 2%. The method comprises two vacuu... | 12/16/2003 |
| 6660514 | Method of preparing recombinant adeno-associated virus compositions Disclosed are methods for the isolation and purification of high-titer recombinant adeno-associated virus (rAAV) compositions. Also disclosed are methods for reducing or eliminating the concentration of helper adenovirus in rAAV samples. Methods are discl... | 12/09/2003 |
| 6565831 | Methods for preventing reovirus recognition for the treatment of cellular proliferative disorders The present invention pertains to methods for preventing reovirus recognition in the treatment of cellular proliferative disorders, and particularly ras-mediated cellular proliferative disorders, in mammals. The method comprises suppressing or otherwise i... | 05/20/2003 |
| 6451581 | Plant branched-chain amino acid biosynthetic enzymes This invention relates to an isolated nucleic acid fragment encoding a branched-chain biosynthetic enzyme. The invention also relates to the construction of a chimeric gene encoding all or a portion of the branched-chain biosynthetic enzyme, in sense or a... | 09/17/2002 |
| 6410311 | Recombinant feline herpesvirus comprising a foreign DNA inserted into a region corresponding to a 3.0 kb EcoRI-SalI fragment of a feline herpesvirus genome This invention provides a recombinant feline herpesvirus comprising a foreign DNA inserted into a feline herpesvirus genome, wherein the foreign DNA is inserted into a region of the genome which corresponds to the 3.0 kb EcoRI-SalI fragment within a SalI ... | 06/25/2002 |
| 6379886 | Diagnostic regeant for hepatitis C virus infection A diagnostic reagent for hepatitis C virus infection obtained by sensitizing a solid phase with HCV antigen and a conjugated antigen prepared by chemical bonding of HCV antigen and a carrier protein, and a method of diagnosing hepatitis C virus infection,... | 04/30/2002 |
| 6379958 | Selected insect cell line clones providing increased yield of baculoviruses and gene expression products from recombinant baculoviruses Three new insect cell lines have been established and characterized. The cloned cell lines are derived from IPLB-Sf-21AE and can grow in serum-free medium. When infected with baculovirus, the cell lines of the invention produce large quantities of baculov... | 04/30/2002 |
| 6232099 | Method of producing a chimeric protein A method of producing a chimeric protein from ie a plant virus coding for such a protein. The method allows the production of large (ie 25 kDa) proteins which assemble with the virus in infected host cells and are arranged on the outer surface of chimeric... | 05/15/2001 |
| 6197568 | Method and compositions for isolation, diagnosis and treatment of polyanion-binding microorganisms Methods and compositions for the isolation, diagnosis and treatment of microorganisms such as flaviviruses and other hemorrhagic fever viruses are based on the sulfated polyanion-dependent interaction of flaviviruses and hemorrhagic fever viruses, in part... | 03/06/2001 |
| 6174690 | Cell bioassay of neurotoxins A cell bioassay is provided for determining the presence in a fluid sample of a sodium channel-activating toxin wherein (a) a fluid sample is incubated in the presence of a culture of cells which express voltage-gated sodium channels and which are respons... | 01/16/2001 |
| 6153378 | Diagnosis of, and vaccination against, a positive stranded RNA virus using an isolated, unprocessed polypeptide encoded by a substantially complete genome of such virus The unprocessed polyprotein initially translated from the genome of a positive-stranded RNA virus contains epitopic configurations that are not retained in the processed proteins. The structural protein region, in particular, loses an epitopic configurati... | 11/28/2000 |
| 6086892 | Poultry vaccine This invention relates to a novel infectious bronchitis virus (IBV) serotype and to attenuated IBV strains derived therefrom, and also to live or inactivated vaccines made using such IB virus. This invention also relates to a method for protecting poultry... | 07/11/2000 |
| 6037174 | Preparation of serum-free suspensions of human hematopoietic cells or precursor cells Provided are serum-free, animal protein-free media formulations to be used in conjunction with hematopoietic growth factors for the in vitro growth of human neutrophil and megakaryocyte precursors. The medium contains a base medium, corticosteroid, transf... | 03/14/2000 |
| 6022736 | Nucleic acid vectors comprising DNase I hypersensitive sites The present invention provides novel recombinant nucleic acid vectors which may be used to produce -globin as well as other proteins of interest in quantity in the red blood cells of transgenic animals or cell cultures of erythroid lineage. The pre... | 02/08/2000 |
| 5994134 | Viral production process The present invention is directed to a method of producing recombinant viral vectors at high titers incorporating a variety of important advancements over the art. The method of the present invention incorporates multiple features which provide enhanced p... | 11/30/1999 |
| 5932700 | Protein inhibiting the growth of human endometrial fibroblasts A novel cell growth-inhibiting protein is provided. The cell growth-inhibiting protein, obtainable from extract of human uterine endometrial carcinoma, has the amino acid sequence rich in hydrophobic residue at its N-terminal, has a molecular weight of ab... | 08/03/1999 |
| 5922533 | Rapid assay for simultaneous detection and differentiation of antibodies to HIV groups A method of performing a rapid assay for the simultaneous detection and differentiation of the analytes HIV-1 group M. HIV-1 group O and HIV-2 utilizing a sequence specific polypeptide of each analyte as capture reagents. An analytical. device also is pro... | 07/13/1999 |
| 5912113 | Method and apparatus for controlling carbon source concentration in aerobic cultivation of a microorganism The present invention is a method for aerobically cultivating yeast or bacteria in a culture medium of fed-batch, continuous or cell-recycling continuous cultures, wherein the carbon source concentration in the culture medium is maintained at a constant l... | 06/15/1999 |
| 5876922 | Papillomavirus probe and a process for in vitro diagnosis of papillomavirus infections The invention concerns human papillomavirus (HPV) DNA and more particularly the probes derived from these papillomaviruses, as well as the methods of detecting HPV using these probes. These human papillomaviruses are designated as HPV-2d, HPV-10b, HPV-14a... | 03/02/1999 |
| 5871748 | Method of treating viral diseases in animals A method of producing active immunity against a viral disease in an animal subject comprises administering to the subject a vaccine conjugate consisting essentially of a live virus and a neutralizing factor bound to the live virus. The neutralizing factor... | 02/16/1999 |
| 5869463 | Use of neuro-glial cell lines for transplantation therapy Human fetal neuro-derived cell lines are implanted into host tissues. The methods allow for treatment of a variety of neurological disorders and other diseases. A preferred cell line is SVG.... | 02/09/1999 |
| 5858687 | Cell bioassay of neurotoxins A cell bioassay is provided for determining the presence in a fluid sample of a sodium channel-activating toxin wherein (a) a fluid sample is incubated in the presence of a culture of cells which express voltage-gated sodium channels and which are respons... | 01/12/1999 |
| 5843429 | Gonad-specific virus which causes sterility in the corn earworm, Helicoverpa zea Helicoverpa species constitute the most important group of crop pests throughout the world, and scientists have been pursuing the development of biocontrol agents effective for the control of these pests. A virus, the gonad specific virus (GSV), has been ... | 12/01/1998 |
| 5750113 | Poultry vaccine This invention relates to a novel infectious bronchitis virus (IBV) serotype and to attenuated IBV strains derived therefrom, and also to live or inactivated vaccines made using such IB virus.... | 05/12/1998 |
| 5731187 | Process for preparing hepatitis A (HAV) antigens and vaccines Process for preparing hepatitis A (HAV) antigens and vaccines. The HAV virus is multiplied on competent cells, the infected cells are lysed, the supernatant is recovered and the purification is carried out by a chromatographic procedure on an anion-exchange su... | 03/24/1998 |
| 5728386 | Thermostable varicella zoster virus A thermostable varicella zoster virus (tVZV) is useful for the preparation of a vaccine against chickenpox. The tVZV was selected from a population of virus which survived stringent heat inactivation conditions. The surviving virus is used to provide seed... | 03/17/1998 |
| 5728519 | Assay for virulent revertants of attenuated live vaccines and kits therefor The present invention provides a method of classifying an unclassified live poliovirus vaccine as having an acceptable or unacceptable level of neurovirulence, comprising, prior to vaccine administration, the steps of: a) selectively amplifying a region o... | 03/17/1998 |
| 5718902 | Double recombinant vaccinia virus vaccines Vaccines comprising a recombinant vaccinia virus expressing at least two heterologous genes encoding pathogen antigens are described. A first antigen gene is inserted into the thymidine kinase gene of the vaccinia virus and a second antigen gene is insert... | 02/17/1998 |
| 5698431 | Herpes simplex virus mutant UL41NHB A herpes simplex virus (HSV) mutant, UL41NHB, is disclosed which is deficient in the virion host shutoff (vhs) function. This mutant is shown to be profoundly attenuated in its ability to replicate at the periphery and in the nervous system, and in its ab... | 12/16/1997 |
| 5686270 | Production of antigens by self-assembly of polypeptide components Antigens are produced by self-assembly of polypeptide components. The production of bluetongue virus antigens (BTV) in the form of assembled particles comprising separate polypeptide components, particularly proteins VP2, VP3, VP5 and VP7 is described.... | 11/11/1997 |
| 5677179 | Isolation and diagnosis of coronaviruses as a factor in bovine shipping fever, and a cell line for culturing both those and other bovine coronaviruses Coronaviruses can be a significant factor in bovine shipping fever. A new human rectal tumor cell line, HRT-18G, is suitable as a host cell line for the propagation of these bovine respiratory coronavirus-shipping fever viruses, and also is well suited fo... | 10/14/1997 |
