Bizarre Patents
A method to tenderize meat with an explosive shockwave.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7354592 | Genetically modified tumor-targeted bacteria with reduced virulence The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention is also directed to Salmonella sp. containing a genetically mod... | 04/08/2008 |
| 7208286 | Bioluminescent bioreporter integrated circuit devices and methods for detecting ammonia Monolithic bioelectronic devices for the detection of ammonia includes a microorganism that metabolizes ammonia and which harbors a lux gene fused with a heterologous promoter gene stably incorporated into the chromosome of the microorganism and an Optical Applicati... | 04/24/2007 |
| 7083794 | Recombinant vaccines comprising immunogenic attenuated bacteria having RpoS positive phenotype Attenuated immunogenic bacteria having an RpoS+ phenotype, in particular, Salmonella enterica serotype Typhi having an RpoS+ phenotype and methods therefor are disclosed. The Salmonella have in addition to an RpoS+ | 08/01/2006 |
| 6923972 | Methods for use of genetically modified tumor-targeted bacteria with reduced virulence The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The present invention further relates to the therapeutic use of the mutant Salmon... | 08/02/2005 |
| 6863894 | Genetically modified tumor-targeted bacteria with reduced virulence The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention is also directed to Salmonella sp. containing a genetically mod... | 03/08/2005 |
| 6649398 | Method for inducing bacterial growth using autoinducers A bacterial autoinducer and method for isolating and purifying a bacterial autoinducer form a sample comprising the steps of collecting a sample containing the autoinducer, fractionating the sample to isolate fractions corresponding to molecular weights o... | 11/18/2003 |
| 6610531 | Viable dried bacteria produced by drying in the presence of trehalose and divalent cation A method is provided for preserving live bacteria by subjecting an aqueous system containing the growing bacteria to drying without special equipment, in the presence of trehalose with or without the addition of divalent cations as stabilizing agents. Fur... | 08/26/2003 |
| 6447784 | Genetically modified tumor-targeted bacteria with reduced virulence The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention is also directed to Salmonella sp. containing a genetically modified msbB... | 09/10/2002 |
| 6376228 | Heterophil-adapted poultry vaccine A method for vaccinating poultry to prevent salmonellosis and other microbial-related health problems in humans is described. The method involves isolation of a poultry heterophil-adapted strain of a microorganism that may be used in a vaccine. A vaccine ... | 04/23/2002 |
| 6120774 | Heterophil-adapted poultry vaccine A method for vaccinating poultry to prevent salmonellosis and other microbial-related health problems in humans is described. The method involves isolation of a poultry heterophil-adapted strain of a microorganism that may be used in a vaccine. A vaccine ... | 09/19/2000 |
| 5855880 | Avirulent microbes and uses therefor This invention provides immunogenic compositions for the immunization of a vertebrate or invertebrate comprising an avirulent derivative of S. typhi. The derivatives having a mutation of the cya and/or crp and/or cdt genes. The invention also provides imm... | 01/05/1999 |
| 5855879 | Avirulent microbes and uses therefor This invention provides immunogenic compositions for the immunization of a vertebrate or invertebrate comprising an avirulent derivative of S. typhi. The derivatives having a mutation of the cya and/or crp and/or cdt genes. The invention also provides imm... | 01/05/1999 |
| 5792622 | Assay for chemicals A microbiological assay for chemicals, which uses a cell and a reducing dye to quantitatively measure inhibition of electron transport in the cell membrane as a function of chemicals in the substance being tested, is disclosed. This assay and method is re... | 08/11/1998 |
| 5786167 | Method and culture medium for identification of salmonellae The invention comprises a culture medium and method for distinguishing bacteria of Salmonella species from other gram-negative bacteria, especially those belonging to the family Enterobacteriaceae. It is based on the ability of salmonellae to utilize meli... | 07/28/1998 |
| 5750363 | Method for determining the antimicrobial agent sensitivity of a nonparaffinophilic microorganism and an associated apparatus A method for determining the sensitivity of at least one nonparaffinophilic microorganism from a specimen obtained from a patient to an antimicrobial agent. The method includes providing at least one receptacle containing an aqueous solution that does not... | 05/12/1998 |
| 5726031 | Test media and quantitative method for identification and differentiation of biological materials in a test sample A test method and medium for quantitatively identifying and distinguishing biological materials in a test sample. A first biological material has enzyme specificity for a first chromogenic substrate, a second biological material has enzyme specificity for... | 03/10/1998 |
| 5622825 | Efficient gene probe conjugations by an unconventional mixed anhydride method A novel method for conjugating haptens, ligands or luminescent labels to polynucleotides has been developed. This method involves the formation of a mixed anhydride, followed by reaction of the mixed anhydride intermediate with a nucleophilic group-contai... | 04/22/1997 |
| 5580557 | Live, avirulent salmonella choleraesuis vaccine used for inducing an immune response in animals Disclosed herein are methods for attenuating virulent gram negative bacteria to produce avirulent bacteria. The methods comprise passaging the wild-type bacteria through phagocytic cells, such as macrophages or polymorphonuclear leukocytes, or through lys... | 12/03/1996 |
| 5529910 | Method for testing causative microorganisms of food poisioning and reagents therefor A method for testing causative bacterial species of food poisoning which is characterized by using two oligonucleotide primers that hybridize to opposite strands of bacterial DNA specifically, and flank a unique region in the target DNA and amplifying the... | 06/25/1996 |
| 5436001 | Live, avirulent Salmonella choleraesuis vaccine used for inducing an immune response in pigs Disclosed herein are methods for attenuating virulent gram negative bacteria to produce avirulent bacteria. The methods comprise passaging the wild-type bacteria through phagocytic cells, such as macrophages or polymorphonuclear leukocytes, or through lys... | 07/25/1995 |
| 5405754 | Process for obtaining an antigenic reagent useful for the indirect determination of Salmonella typhi The invention described herein consists of a process for preparing an antigenic reagent useful for the indirect determination of Salmonella typhi, the organism that is the causal agent of typhoid fever (TF). The invention consists on the following steps: ... | 04/11/1995 |
| 5387744 | Avirulent microbes and uses therefor: Salmonella typhi This invention provides immunogenic compositions for the immunization of a vertebrate or invertebrate comprising an avirulent derivative of S. typhi. The derivatives having a mutation of the cya and/or crp and/or cdt genes. The invention also provides imm... | 02/07/1995 |
| 5374423 | Method of using cytokine receptors on microorganism Cytokine receptors for tumor necrosis factor e which are found on microorganisms may, if bound with exogenous TNF, enhance the response of natural killer cells activated by the microorganisms, or increase TNF production by peripheral blood l... | 12/20/1994 |
| 5356778 | Method for detection of gram-negative bacterial liposaccharides in biological fluids The invention relates to a method of detecting gram-negative bacterial endotoxin using antibody capture combined with amoebocyte lysate chromogenic detection. The method is highly sensitive and rapid and may be used for detection of specific endotoxin. In... | 10/18/1994 |
| 5294441 | Avirulent microbes and uses therefor: salmonella typhi This invention provides immunogenic compositions for the immunization of a vertebrate or invertebrate comprising an avirulent derivative of S. typhi. The derivatives having a mutation of the cya and/or crp and/or cdt genes. The invention also provides imm... | 03/15/1994 |
| 5270038 | Tumor necrosis factor receptors on microorganisms Cytokine receptors for tumor necrosis factor which are found on microorganisms may, if bound with exogenous TNF, enhance the response of natural killer cells activated by the microorganisms, or increase TNF production by peripheral b... | 12/14/1993 |
| 5215919 | Process for producing optically active 2-hydroxycycloalkanecarboxylic acid esters using microbially derived reductase A (1R,2S)-2-hydroxycycloalkanecarboxylic acid ester is efficiently and selectively produced by microbial asymmetric reduction of a 2-oxocycloalkanecarboxylic acid ester with a bacterial strain or its processed material.... | 06/01/1993 |
| 5210035 | Non-reventing live vaccines Live vaccines are provided and methods for preparing the live vaccines for protection of a host from a pathogenic microorganism. The vaccines are prepared by introducing at least one modification in a gene involved in at least one, normally at least two, ... | 05/11/1993 |
| 5198339 | Method for detection of gram-negative bacterial lipopolysaccharides in biological fluids The invention relates to a method of detecting gram-negative bacterial endotoxin using antibody capture combined with amoebocyte lysate chromogenic detection. The method is highly sensitive and rapid and may be used for detection of specific endotoxin. In... | 03/30/1993 |
| 5194374 | Isolating medium for identifying the Salmonella bacterium The present invention relates to an isolating medium for the identification of the Salmonella bacterium, wherein a polyol metabolizable by Salmonella and a pH indicator reacting to acidification are added to a culture support containing peptones.... | 03/16/1993 |
| 5162226 | Therapeutic compositions against streptococcal infections, transformed hosts, methods of immunization and genetically engineered products Non-virulent aro-Salmonella typhimurium bacterium is disclosed into which has been cloned a heterologous nucleotide sequence encoding for the expression of Streptococcal M protein antigen from S. pyogenes seratype 5, which is effective to elicit opsonic a... | 11/10/1992 |
| 5147778 | Probes and methods for the detection of salmonella Improved nucleic acid probes capable of specifically hybridizing to rRNA of Salmonella and not to rRNA of non-Salmonella are described along with methods utilizing such probes for the detection of Salmonella in food and other samples.... | 09/15/1992 |
| 5112749 | Vaccines for the malaria circumsporozoite protein The present invention is directed to attenuated strains of enteroinvasive bacteria that express a peptide or protein related to an epitope of the malaria parasites of the genus Plasmodium. The bacterial strains of the invention which can multiply in a hos... | 05/12/1992 |
| 5084565 | Probes for the specific detection of Escherichia coli and Shigella Nucleic acid probes capable of specifically hybridizing to rRNA of E. coli and Shigella species and not to rRNA of non-E. coli/Shigella are described along with methods utilizing such probes for the specific detection of E. coli and/or Shigella in food an... | 01/28/1992 |
| 5079165 | Production of the E. coli LT-B enterotoxin subunit in S. typhi Methods and compositions are provided for the cloning and expression of plasmids bearing genes coding for the non-toxic subunit of the heat-laible enterotoxin (LT-B) of E. coli. These plasmids may be cloned into stable avirulent strains of Salmonella typh... | 01/07/1992 |
| 5055394 | Nucleic acid probe and method for the rapid detection of typhoid fever bacteria This invention relates to a nucleic acid probe and method for the rapid detection of typhoid fever bacteria by use of a nucleic acid hybridization probe, equivalent to the DNA region encoding the Vi antigen of enteric bacteria such as Salmonella typhi, S.... | 10/08/1991 |
| 5043264 | DNA probes for detecting salmonella and a method for detecting salmonella therewith A novel probe for detecting Salmonella comprises: a labeled substance, and a DNA or RNA fragment which hybridizes with a base sequence having the following formula (I), or (II) being complementary to the formula (I). 5'-GCTCAGACGTATGGCGGTA-3' ... | 08/27/1991 |
| 5021234 | Agent and product for the diagnosis and treatment of tumors and for the treatment of weaknesses of the cellular and humoral immune defense An agent for the diagnosis and treatment of malignant tumors and for the treatment of lowered cellular and humoral immune defense is described which contains an immune modulator, a lipopolysaccharide or an immune modulator tagged with a radioactive tracer... | 06/04/1991 |
| 4943521 | Method for evaluating mutagenicity A method for rapidly and reliably determining the potential carcinogenic activity of hydrocarbon mixtures which is especially useful for those of petroleum origin. A sample of the mixture is nitrated under conditions effective to convert the polynuclear a... | 07/24/1990 |
| 4920063 | Process for detection of selected motile organisms Methods and associated devices for detecting the presence of a particular motile organism within a sample are disclosed. The sample may be derived from dry milk, raw meat, poultry or a clinical specimen. A preferred method includes inoculating a selective... | 04/24/1990 |
