Did You Know...
...that to encourage use of his new invention, the shopping cart, market owner Sylvan Goldman hired fake shoppers to push the carts around his store in Oklahoma City? Seems his customers were reluctant to give up their hand-carried baskets.
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| Number | Title | Issue Date |
| 8129148 | Process for preparation of chondroitin fraction Provided are a method for producing a fraction containing more than 50% of CH represented by the general formula (1), which comprises at least the step of allowing a glucuronic acid donor, an N-acetylgalactosamine donor, a saccharide receptor, a chondroitin polymera... | 03/06/2012 |
| 7888072 | Heparan sulfate glycosaminoglycan lyase and uses thereof The invention provides recombinant B. thetaiotaomicron GAG lyase polypeptides. The invention also provides nucleic acid molecules encoding such polypeptides, recombinant expression vectors containing B. thetaiotaomicron GAG lyase nucleic acid molecules... | 02/15/2011 |
| 7767420 | Heparan sulfate glycosaminoglycan lyase and uses thereof The invention provides recombinant B. thetaiotaomicron HSGAG lyase polypeptides. The invention also provides nucleic acid molecules encoding such polypeptides, recombinant expression vectors containing B. thetaiotaomicron HSGAG lyase nucleic acid molec... | 08/03/2010 |
| 7691613 | Glycosaminoglycan lyase IV and uses thereof The invention provides recombinant B. thetaiotaomicron GAG lyase polypeptides. The invention also provides nucleic acid molecules encoding such polypeptides, recombinant expression vectors containing B. thetaiotaomicron GAG lyase nucleic acid molecules... | 04/06/2010 |
| 7691612 | Heparan sulfate glycosaminoglycan lyase and uses thereof The invention provides recombinant B. thetaiotaomicron GAG lyase polypeptides. The invention also provides nucleic acid molecules encoding such polypeptides, recombinant expression vectors containing B. thetaiotaomicron GAG lyase nucleic acid molecules... | 04/06/2010 |
| 7405267 | Method for purifying teicoplanin A Disclosed is a method for purifying teicoplanin A2 comprising: (i) a primary pre-purification step of purifying a filtrate of fermentation broth of a strain using a synthetic adsorbent; (ii) a secondary pre-purification step of purifying the primary pre-p... | 07/29/2008 |
| 7335500 | Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose This invention contemplates improved methods of enzymatic production of carbohydrates especially fucosylated carbohydrates. Improved syntheses of glycosyl 1- or 2-phosphates using both chemical and enzymatic means are also contemplated. The phosphorylated glycosides... | 02/26/2008 |
| 7329514 | Process for producing n-acetylneuraminic acid In the process for producing N-acetylneuraminic acid by using a microorganism having the ability to produce N-acetylneuraminic acid, the present invention provides economical and efficient process for producing N-acetylneuraminic acid by using a microorganism in whi... | 02/12/2008 |
| 7270980 | Compounds for immunodiagnosis of prostate cancer and methods for their use Compounds and methods for diagnosing prostate cancer are provided. The inventive compounds include polypeptides containing at least a portion of a prostate tumor protein. The inventive polypeptides may be used to generate antibodies useful for the diagnosis and moni... | 09/18/2007 |
| 7257976 | Spiral cooling of steel workpiece in a rolling process A hollow cooling box for a steel mill to be used to cool a hot steel work piece as it passes through the cooling box; the box having an interior plenum formed by the members forming the cooling box. The plenum is supplied with coolant under pressure, and the coolant... | 08/21/2007 |
| 7241587 | Method of uncoupling the catabolic pathway of glycolysis from the oxidative membrane bound pathway of glucose conversion The invention provides methods for producing products comprising improved host cells genetically engineered to have uncoupled productive and catabolic pathways. In particular, the present invention provides host cells having a modification in nucleic acid encoding a... | 07/10/2007 |
| 7232675 | Sulfotransferase, its polypeptide and DNA encoding the same A glycosaminoglycan sulfotransferase, a peptide thereof, a nucleic acid comprising a nucleotide sequence encoding the same, an enzyme agent for the synthesis of a glycosaminoglycan, which comprises the above-described enzyme or polypeptide, and a process for produci... | 06/19/2007 |
| 7217558 | Microorganism producing 5'xanthylic acid The invention relates to Corynebacterium ammoniagenes CJXOL 0201 KCCM 10447 producing 5′-xanthylic acid. More specifically, the invention relates to Corynebacterium ammoniagenes CJXOL 0201 KCCM 10447 which is a mutant strain of Corynebacterium amm... | 05/15/2007 |
| 7138262 | High mannose proteins and methods of making high mannose proteins The invention features a method of producing a high mannose glucocerebrosidase (hmGCB) which includes: providing a cell which is capable of expressing glucocerebrosidase (GCB), and allowing production of GCB having a precursor oligosaccharide under conditions which ... | 11/21/2006 |
| 7122653 | Reagents and methods useful for detecting diseases of the prostate A set of contiguous and partially overlapping RNA sequences and polypeptides encoded thereby, designated as PS190 and transcribed from prostate tissue is described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preve... | 10/17/2006 |
| 7094582 | Cell-free production of glucosamine Methods for cell-free production of glucosamine from starch, maltodextrin or glycogen or from fructose and a source of amino groups are disclosed. Also disclosed are cellular extracts comprising glucosamine-6-phosphate synthase activity, as well as a cellular extrac... | 08/22/2006 |
| 7078195 | Antibiotics AA-896 This invention relates to new antibiotics designated AA-896-A1, AA-896-A2, AA-896-A3, AA-896-A4, AA-896-A5, AA-896-A6, AA-896-Bl, AA-896-B2, AA-896-B3, AA-896-B4, AA-896-B5, AA-896-B6, AA-896-B7, AA-896-C1, AA-896-C2, AA-896-C3, AA-896-C4, AA-896-C5, AA-896-D1, AA-8... | 07/18/2006 |
| 6887979 | Method of preventing decrease in the activity of protein due to freezing and use of polypeptide in the production of protein activity decrease preventing agent An objective of the present invention is to provide a means to prevent freeze-induced decrease in protein activity. The present invention relates to a method for preventing freeze-induced decrease in protein activity comprising adding a polypeptide comprising the fo... | 05/03/2005 |
| 6780616 | Antibiotic caprazamycins and process for producing the same There have been obtained, by cultivation of Streptomyces sp. MK730-62F2 (deposit number of FERM BP-7218), antibiotic caprazamycins A to F having by the following general formula (I) wherein R is tridecyl group, 11-methyl... | 08/24/2004 |
| 6753154 | Human AZU-1 gene, variants thereof and expressed gene products A human AZU-1 gene, mutants, variants and fragments thereof. Protein products encoded by the AZU-1 gene and homologs encoded by the variants of AZU-1 gene acting as tumor suppressors or markers of malignancy progression and tumorigenicity reversion. Identification, ... | 06/22/2004 |
| 6709834 | Lipopolysaccharide α-2,3 sialytransferase of campylobacter jejuni and its uses The structure and specificity of a recombinant α2,3-sialyltransferase from Campylobacter spp., is disclosed. Also provided are methods for using the α2,3-sialyltransferase in the production of desired carbohydrate structures and nucleic acids that encode the sialy... | 03/23/2004 |
| 6649753 | Stable salts of S-adenosyl-L-methionine (SAMe) and the process for their preparation This invention relates to the production of new & stable salts of S-adenosyl-L-methionine SAMe). The source of SAMe used in the salt formation is from chemical process wherein stereoselective methylation of S-adenosyl-L-homocysteine is achieved. The proce... | 11/18/2003 |
| 6197552 | Process for preparing 2,6-diaminopurine-2'-deoxyriboside and 2'-deoxyguanosine A process for preparing 2,6-diaminopurine-2'-deoxyriboside and 2'-deoxyguanosine. These compounds may be used as materials for pharmaceuticals, such as antiviral agents and the like, and particularly as starting materials for antisense oligonucleotides.... | 03/06/2001 |
| 6190888 | Process for making riboflavin glucoside A process for producing riboflavin glucoside comprises cultivating a microorganism belonging to the genus Bacillus, such as Bacillus brevis, Bacillus cereus, Bacillus circulans, Bacillus coagulans, Bacillus licheniformis, Bacillus megaterium, Bacillus pum... | 02/20/2001 |
| 6168934 | Oligosaccharide enzyme substrates and inhibitors: methods and compositions Oligosaccharide compounds that are substrates and inhibitors of glycosyltransferase and glycosidase enzymes and compositions containing such compounds are disclosed. A method of glycosylation is also disclosed. An E. coli transformed with phagemid CMPSIL-... | 01/02/2001 |
| 6130072 | Osmotically controlled fermentation process for the preparation of acarbose The invention relates to a novel fermentative process for the preparation of acarbose. By monitoring and controlling the osmolality in the fermentation solution, a substantial improvement in yield from the fermentation is achieved.... | 10/10/2000 |
| 6127152 | Process for producing nucleoside derivatives There is disclosed a process for producing a nucleoside derivative of the formula [I]: ##STR1## characterized by contacting 2',3',5'-O-triacylribonucleoside derivative of the formula [II]: ##STR2## with an ester hydrolase: (i) capable of re... | 10/03/2000 |
| 6087132 | Multi-functional enzymes including derivable 2'3'-dideoxyribofuranoside triprosphates The invention relates to a multifunctional nucleoside didesoxyribosyl or nucleoside deoxyribosyl transferase which has one or more of the following additional activities (desoxy) nucleoside kinase, nucleoside reductase desaminase, or DNA polymerase activi... | 07/11/2000 |
| 6040158 | Process for preparing sugar nucleotide A process for preparing a sugar nucleotide from a nucleotide by using a yeast cell, characterized in that both a nucleoside diphosphate-sugar pyrophosphorylase and a sugar 1-phosphate are present in the reaction system. According to this process, various ... | 03/21/2000 |
| 6017736 | Method of preparing purine nucleoside compound The present invention provides a method of preparing stably and at a high yield a purine nucleoside compound by utilizing an exchange reaction of a nucleic acid base which is carried out in the presence of an enzyme, and also provides a microorganism capa... | 01/25/2000 |
| 5968783 | Process for the preparation of sugar nucleotides The present invention relates to a process for preparing sugar nucleotides from nucleotides and sugar derivatives by the use of yeast, characterized in that the reactions are conducted at 20° C. or below. According to this process, even when the preparat... | 10/19/1999 |
| 5939290 | Modified sialyl Lewisx compounds The present invention is drawn to methods for the synthesis of sialyl Lewisx derivatives modified at the C-2 and/or C-6 position of GlcNAc employing chemoenzymatic synthesis. The derivatives find use in the treatment and prevention of diseases.... | 08/17/1999 |
| 5882901 | Modified sialyl Lewisa compounds The present invention is drawn to methods for the synthesis of Lewisa derivatives modified at the C-2 and/or C-6 position of GlcNAc employing chemo-enzymatic synthesis. The derivatives find use in the treatment and prevention of diseases.... | 03/16/1999 |
| 5866377 | Aminooligosaccharide derivative and process for preparing the same The present invention relates to novel aminooligosaccharide derivative and pharmaceutically acceptable non-toxic salts thereof, which possess potent saccharide hydrolase inhibition and antibacterial activities. The invention also relates to a process for ... | 02/02/1999 |
| 5856300 | Compositions comprising complement related proteins and carbohydrates, and methods for producing and using said compositions The present invention provides compositions comprising at least one complement moiety and at least one carbohydrate moiety, and methods of producing such compositions. In particular, the compositions of the invention comprise complement proteins related t... | 01/05/1999 |
| 5834251 | Methods of modifying carbohydrate moieties The invention is directed to methods of converting high mannose type glycosylation patterns to hybrid or complex type glycosylation patterns.... | 11/10/1998 |
| 5789204 | Biosorbent for heavy metals prepared from biomass The object of this invention is to provide a biosorbent for heavy metals having polyaminosaccharide sodiumphosphate as main ingredient prepared from microbial biomass using Aspergillus, Penicillium, Trichoderma or Micrococcus genus originating from indust... | 08/04/1998 |
| 5759823 | Ogligosaccharide enzyme substrates and inhibitors: methods and compostions Oligosaccharide compounds that are substrates and inhibitors of glycosyltransferase and glycosidase enzymes and compositions containing such compounds are disclosed. A method of glycosylation is also disclosed. An E. coli transformed with phagemid CMPSIL-... | 06/02/1998 |
| 5674715 | Method for producing uridine diphosphate N-acetylgluosamine A method for producing uridine diphosphate N-acetylglucosamine comprising culturing osmo-tolerant yeasts in aerobic conditions in a medium having inorganic salt concentration of about 2-8%.... | 10/07/1997 |
| 5643760 | Microbial process for preparation of indolopyrrolocarbazole derivatives Indolopyrrolocarbazole derivatives, such as, for example, 12,13-dihydro-1,11-dihydroxy-13-(ଲ-D-glucopyranosyl)-5H-indolo[2,3-a] pyrrolo[3,4-c]carbazole-5,7-(6H)-dione or 6-amino derivative thereof, are produced by glycosylating a precursor compound b... | 07/01/1997 |
