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| Number | Title | Issue Date |
| 7368277 | Method for assay of antibodies and antibody assay device The invention relates to a technology by which antibodies directed to sources of infection in body fluids can be assayed with high accuracy, expediency and specificity. More particularly, the invention provides an antibody immunoassay method in which the antigen-ant... | 05/06/2008 |
| 7208286 | Bioluminescent bioreporter integrated circuit devices and methods for detecting ammonia Monolithic bioelectronic devices for the detection of ammonia includes a microorganism that metabolizes ammonia and which harbors a lux gene fused with a heterologous promoter gene stably incorporated into the chromosome of the microorganism and an Optical Applicati... | 04/24/2007 |
| 7163820 | strain for an oral vaccine against post-weaning diarrhea in pigs The invention relates to a strain suitable for producing a live, orally applicable Escherichia coli vaccine for the prevention of post-weaning diarrhoea in pigs, and the procedure suitable for producing that strain. The essence of the strain is that the enter... | 01/16/2007 |
| 7138237 | Diagnosis, prevention and treatment of Crohn's disease using the OmpC antigen The present invention provides a method of diagnosing Crohn's disease in a subject by determining the presence or absence of IgA anti-OmpC antibodies in the subject, where the presence of the IgA anti-OmpC antibodies indicates that the subject has Crohn's disease. | 11/21/2006 |
| 7115389 | Method for producing dipeptide A method for producing a dipeptide including the step of exposing a carboxy component and an amine component to an enzyme having an activity to hydrolyze amino acid ester. Such a hydrolase has been found among enzymes in bacteria. The method is useful for producing ... | 10/03/2006 |
| 7052884 | L-arginine producing and method of producing L-arginine Arginine can be efficiently produced by cultivating Escherichia coli which has an ability to produce arginine and an ability to utilize acetate in a culture medium to produce and accumulate arginine in the medium, and collecting arginine from the medium. ... | 05/30/2006 |
| 7025971 | Treatment or prophylaxis of diseases caused by pilus-forming bacteria Novel methods for the treatment and/or prophylaxis of diseases caused by tissue-adhering bacteria are disclosed. By interacting with periplasmic molecular chaperones it is achieved that the assembly of pili is prevented or inhibited and thereby the infectivity of th... | 04/11/2006 |
| 7018629 | Probiotic compositions for the treatment of inflammatory bowel disease Pharmaceutical compositions of probiotic E. coli strains and uses thereof for treating inflammatory bowel disease. ... | 03/28/2006 |
| 6994985 | Development of anti-sigma factor agents Sigma factors are a unique family of essential proteins found in bacterial, but not eukaryotic cells, which are responsible for recognition of promoter DNA and delivery of the catalytic domain of RNA polymerase to a gene signaled to be expressed. The present inventi... | 02/07/2006 |
| 6962791 | Treatment or prophylaxis of diseases caused by pilus-forming bacteria Novel methods for the treatment and/or prophylaxis of diseases caused by tissue-adhering bacteria are disclosed. By interacting with periplasmic molecular chaperones it is achieved that the assembly of pili is prevented or inhibited and thereby the infectivity of th... | 11/08/2005 |
| 6960464 | Methods for lyophilizing competent cells This invention relates to a method for producing cells which are competent for transformation and which may be stably stored for extended periods of time at various temperatures. The method involves growing cells in a growth conducive medium, rendering said cells co... | 11/01/2005 |
| 6841365 | L-arginine producing Escherichia coli and method of producing L-arginine Arginine can be efficiently produced by cultivating Escherichia coli which has an ability to produce arginine and an ability to utilize acetate in a culture medium to produce and accumulate arginine in the medium, and collecting arginine from the medium. ... | 01/11/2005 |
| 6806070 | Use of bacterial extracts of the pseudomonadaceae family as cosmetic agents Use of an extract of bacterium from the family Pseudomonadaceae in the production of cosmetic compositions in particular for combating ageing of the skin. ... | 10/19/2004 |
| 6756216 | Process for producing non-proteinogenic L-amino acids by fermentation Process for production of non-protenogenic L-amino acids by direct fermentation of a microorganism strain known per se having a deregulated cysteine metabolism in a manner known per se, which comprises adding, during the fermentation, a nucleophilic compound to the ... | 06/29/2004 |
| 6706517 | Method for producing L-amino acids by fermentation The present invention provides an industrially efficient method for producing an L-amino acid useful as medicament, chemical agent, food material and feed additive, and the method comprising culturing in a medium a microorganism having an ability to produce the L-am... | 03/16/2004 |
| 6660516 | Method for culturing a microorganism and promoting microbial growth and metabolism A method is provided for culturing a microorganism in a culture medium containing a carbon source and an electrolyzed water containing not more than 0.4 ppm chlorine produced during electrolyzing water containing an electrolyte in an electrolytic cell. Th... | 12/09/2003 |
| 6653112 | Method for producing L-carnitine from crotonobetaine using a two stage continuous cell-recycle reactor L(-)-carnitine is synthesized from crotonobetaine, crotonobetaine salts or derivatives in an ecologically advantageous manner by immobilizing cells of Escherichia coli 044 K74 on ceramics, glass beads or polyurethane disks in a two stage continuously oper... | 11/25/2003 |
| 6649398 | Method for inducing bacterial growth using autoinducers A bacterial autoinducer and method for isolating and purifying a bacterial autoinducer form a sample comprising the steps of collecting a sample containing the autoinducer, fractionating the sample to isolate fractions corresponding to molecular weights o... | 11/18/2003 |
| 6610531 | Viable dried bacteria produced by drying in the presence of trehalose and divalent cation A method is provided for preserving live bacteria by subjecting an aqueous system containing the growing bacteria to drying without special equipment, in the presence of trehalose with or without the addition of divalent cations as stabilizing agents. Fur... | 08/26/2003 |
| 6602688 | Cytoplasmic expression of antibodies, antibody fragments and antibody fragment fusion proteins in E. coli The invention relates to the cytoplasmic expression of antibodies, antibody fragments and antibody fragment fusion molecules in E. coli. In particular, antibody fragment fusion molecules having an antibody moiety which is directed against tumors and an en... | 08/05/2003 |
| 6589771 | Methods for arousing dormant bacteria A method for arousing dormant bacteria. The method comprises inducing diffusion of intracellular solutes from dormant bacteria and then allowing an adjustment period for a length of time sufficient to initiate arousal. The decrease in intracellular osmola... | 07/08/2003 |
| 6558678 | PREPARATION AND USE OF FORMALIN-KILLED COLONIZATION-FACTOR-ANTIGEN (CFA)-EXPRESSING E. COLI ORGANISMS FOR VACCINATION AGAINST ENTERIC INFECTION/DIARRHEA CAUSED BY ENTEROTOXIGENIC E. COLI BACTERIA IN HUMANS Disclosed is a method of producing a vaccine composition against enteric infection caused by enterotoxigenic E. coli bacteria in humans. E. coli strains selected from different known strains each having the ability of expressing a certain type of coloniza... | 05/06/2003 |
| 6537772 | Equipment, kit and method for microbiological diagnosis The present invention is related to microbiology and forms part of a system for rapid microbiological diagnosis. The invention allows detection of turbidimetric changes due to microbial growth, using equipment comprised of two main devices: a static turbi... | 03/25/2003 |
| 6472169 | Biocatalytic synthesis of shikimic acid A bioengineered synthesis scheme for the production of shikimic acid from a carbon source is provided. Methods of producing shikimic acid from a carbon source based on the synthesis scheme are also provided.... | 10/29/2002 |
| 6471966 | Type 1 and type p fimbriae-adhesins isolated from novel e. coli strains, process for their preparation and uses thereof Fimbriae adhesins have a molecular weight of 2×105 and 2×107 Da, and are comprised of 90-95% protein and 1-3% sugar. Type 1 fimbriae include five different protein fractions of 14-20 kDa, most of which are associated with carbohydr... | 10/29/2002 |
| 6420127 | Compounds and pharmaceutical compositions for the treatment and prophylaxis of bacterial infections Novel methods for the treatment and/or prophylaxis of diseases caused by tissue-adhering bacteria are disclosed. By interacting with periplasmic molecular chaperones it is achieved that the assembly of pili is prevented or inhibited and thereby the infect... | 07/16/2002 |
| 6387652 | Method of identifying and quantifying specific fungi and bacteria Fungi and bacteria can be detected and rapidly quantified by using the nucleotide sequences taught here that are specific to the particular species or group of species of fungi or bacteria. Use of the sequences can be made with fluorescent labeled probes,... | 05/14/2002 |
| 6365368 | Rapid method for the detection and quantification of microbes in water The present invention concerns methods of testing water for microbe contamination. The methods of the invention comprise supplementing existing methods with assays using specific reagents such as monoclonal antibodies. The invention also concerns a device... | 04/02/2002 |
| 6309861 | Process for the production of naturally folded and secreted proteins A process produces a water-soluble, naturally folded eukaryotic polypeptide containing two or several cysteines linked by disulfide bridges. This process involves culturing prokaryotic cells, a) in which the prokaryotic cells contain an expression vector ... | 10/30/2001 |
| 6300105 | Methods for producing a succinimide polymer, an aspartic acid polymer and L-aspartic acid A succinimide polymer is produced by thermally polymerizing an ammonium salt of aspartic acid in the presence of an acid catalyst such as a boric acid catalyst. Another amino acid may be added for copolymerizing with the ammonium salt of aspartic acid. Am... | 10/09/2001 |
| 6268471 | Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof The invention includes a gene encoding csrA, the protein encoded thereby and methods of use thereof.... | 07/31/2001 |
| 6242210 | Treatment of bacterial infections An assay for compounds useful in the treatment of a bacterial induced coagulation disorder has the following steps: a) incubating a plasma sample with a strain of bacteria; b) adding a compound to be assayed to the plasma sample before, during or after step (a... | 06/05/2001 |
| 6218163 | Stable biocatalysts for ester hydrolysis The instant invention encompasses isolated stable esterase enzymes characterized by the ability to remain stable at certain temperatures, substrate specificities, and activity profile.... | 04/17/2001 |
| 6180373 | Microorganisms for the production of tryptophan and process for the preparation thereof A tryptophan producing strain of microorganism is selected from E. coli and Corynebacteria and is tryptophan feedback resistant and serine feedback resistant. The serine feedback resistance is by a mutation in a serA allele, where the mutated serA allele ... | 01/30/2001 |
| 6153396 | Treatment or prophylaxis of diseases caused by pilus-forming bacteria Novel methods for the treatment and/or prophylaxis of diseases caused by tissue-adhering bacteria are disclosed. By interacting with periplasmic molecular chaperones it is achieved that the assembly of pili is prevented or inhibited and thereby the infect... | 11/28/2000 |
| 6143552 | Process for producing L-amino acids by fermentation The present invention provides a process for producing an L-amino acid which comprises culturing in a nutrient medium a microorganism which is capable of producing the L-amino acid and which can not grow in a synthetic medium containing said L-amino acid ... | 11/07/2000 |
| 6133021 | Bioreactor system and method for probing toxic materials A bioreactor system of probing toxic materials using microorganisms comprises two reactors. A first-step reactor serves as a microorganism reservoir in which the microorganisms are continuously cultured in a constant phase and a second-step reactor, provi... | 10/17/2000 |
| 6130085 | Recombinant vector containing a sequence of a lipoprotein gene for the expression of nucleotide sequences A recombinant vector for cloning a heterologous nucleotide sequence and/or expressing it and/or transferring it to a cell host. The vector includes, at a site which is not essential for replication, the gene coding for a lipoprotein other than E. coli lip... | 10/10/2000 |
| 6114157 | Method for increasing total production of 4-hydroxybenzoic acid by biofermentation This invention pertains to a method of production of 4-hydroxybenzoic acid, with purification and recovery of 4-hydroxybenzoic acid directly from the fermentation medium of a cultured organism, in the presence of other chemical species. Ion exchange resin... | 09/05/2000 |
| 6096516 | cDNAs encoding murine antibody against human plasma apolipoprotein B-100 The present invention relates to cDNAs encoding murine antibodies against apolipoprotein B-100, the protein moiety of low density lipoprotein(LDL) in human plasma. In addition, the present invention relates to the method of preparation of recombinant anti... | 08/01/2000 |
