"I watched his countenance closely, to see if he was not deranged ... and I was assured by other senators after he left the room that they had no confidence in it."
U.S. Senator Smith of Indiana ; After seeing Samuel Morse demonstrate the telegraph.
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7217541 | Method of making CS6 antigen vaccine for treating, preventing, or inhibiting enterotoxigenic infections Disclosed herein are methods for making large amounts of highly pure colonization factors. The methods of the present invention differ from prior art methods in that host cells which express the colonization factor of interest are cultured in media comprising more t... | 05/15/2007 |
| 7163820 | strain for an oral vaccine against post-weaning diarrhea in pigs The invention relates to a strain suitable for producing a live, orally applicable Escherichia coli vaccine for the prevention of post-weaning diarrhoea in pigs, and the procedure suitable for producing that strain. The essence of the strain is that the enter... | 01/16/2007 |
| 6833264 | Hyaluronan synthase gene and uses therof The present invention relates to a nucleic acid segment having a coding region segment encoding enzymatically active Streptococcus equisimilis hyaluronate synthase (seHAS), and to the use of this nucleic acid segment in the preparation of recombinant cells wh... | 12/21/2004 |
| 6537772 | Equipment, kit and method for microbiological diagnosis The present invention is related to microbiology and forms part of a system for rapid microbiological diagnosis. The invention allows detection of turbidimetric changes due to microbial growth, using equipment comprised of two main devices: a static turbi... | 03/25/2003 |
| 6387652 | Method of identifying and quantifying specific fungi and bacteria Fungi and bacteria can be detected and rapidly quantified by using the nucleotide sequences taught here that are specific to the particular species or group of species of fungi or bacteria. Use of the sequences can be made with fluorescent labeled probes,... | 05/14/2002 |
| 6365368 | Rapid method for the detection and quantification of microbes in water The present invention concerns methods of testing water for microbe contamination. The methods of the invention comprise supplementing existing methods with assays using specific reagents such as monoclonal antibodies. The invention also concerns a device... | 04/02/2002 |
| 6242210 | Treatment of bacterial infections An assay for compounds useful in the treatment of a bacterial induced coagulation disorder has the following steps: a) incubating a plasma sample with a strain of bacteria; b) adding a compound to be assayed to the plasma sample before, during or after step (a... | 06/05/2001 |
| 6103508 | Method for removing fumarase activity, microorganisms obtainable by the method, and production of optically active aminopolycarboxylic acids using the microorganisms This invention relates to a method for removing fumarase activity from a microorganism or processed product thereof having ethylenediamine-N,N'-disuccinic acid ethylenediamine lyase activity, which includes treating the microorganism or processed product ... | 08/15/2000 |
| 6060266 | Self-contained incubator for growth of microorganism A self-contained incubator for growth of microorganism kit and methods for use of such a kit are provided. The kit and methods may detect the presence of microorganisms and may utilie a microorganism growth and indicator medium provided in a sample contai... | 05/09/2000 |
| 5948610 | Use of matrices comprising liquids and light absorbing particles for analysis of microorganisms by laser desorption mass spectrometry The present invention is directed to a method of using a liquid matrix containing a black body light absorbing powder to facilitate the analysis of biomarkers from representative microorganisms by laser desorption mass spectrometry. Both an IR laser (1064... | 09/07/1999 |
| 5869321 | Thin film culture plate device containing granulated medium particles The present disclosure reports a thin film culture plate device including i) a self-supporting, waterproof substrate containing a layer of a unique reconstitutable culture medium made of nutrients for growing microorganisms, and a mixture of gelling agent... | 02/09/1999 |
| 5861270 | Enzymatic method for detecting coliform bacteria or E. coli A two stage enzymatic method for the detection of coliform bacteria or E. coli wherein bacteria are concentrated on a membrane filter. This filter is placed on a growth medium containing nutrients, including preferably minerals, a protein hydrolysate and ... | 01/19/1999 |
| 5849515 | Method and medium for use in detecting E. coli and total coliforms A selective culture medium which permits simultaneous detection of total coliform and Escherichia coli in a test sample with a single growth phase incubation period. The culture medium includes the required components of: (i) carbon nutrients, (ii) a nitr... | 12/15/1998 |
| 5792617 | Cell proliferation-based amplified detection of analytes A test kit and method for the highly sensitive detection of specific analytes in a sample is provided. The presence of the analyte in the sample results in a decrease in the concentration of a growth inhibiting substance leading to proliferation of cells ... | 08/11/1998 |
| 5789191 | Method of detecting and counting microorganisms The invention provides a cosmetic or dermatological method for detecting and/or selectively quantifying individual microorganisms, and/or whole groups of microorganisms, which are present on human or animal skin, comprising the steps of removing a sample ... | 08/04/1998 |
| 5763231 | Process for producing L-leucine A process for producing L-leucine, which includes incubating an L-leucine-productive microorganism belonging to the genus Corynebacterium, Escherichia, Brevibacterium, or Microbacterium in a culture medium and reacting the resulting cells with saccharides... | 06/09/1998 |
| 5750363 | Method for determining the antimicrobial agent sensitivity of a nonparaffinophilic microorganism and an associated apparatus A method for determining the sensitivity of at least one nonparaffinophilic microorganism from a specimen obtained from a patient to an antimicrobial agent. The method includes providing at least one receptacle containing an aqueous solution that does not... | 05/12/1998 |
| 5650290 | Method & Medium for use in detecting E. coli and total coliforms A selective culture medium which permits simultaneous detection of total coliform and Escherichia coli in a test sample with a single growth phase incubation period. The culture medium includes the required components of: (i) carbon nutrients, (ii) a nitr... | 07/22/1997 |
| 5601998 | Culture medium and device for detection and enumeration of enterobacteriaceae This invention generally relates to products and processes used to determine the presence of Enterobacteriaceae in a sample and particularly relates to a bacterial culture medium which may be used in products and processes to allow early detection and enu... | 02/11/1997 |
| 5525718 | Oligonucleotides for detecting bacteria and detection method using same Oligonucleotides (SEQ ID NOs 1-8) selectively hybridizable with a specific gene of Vibro parahaemolyticus, oligonucleotides (SEQ ID NOs 9-13) selectively hybridizable with the LT gene of toxigenic Escherchia coil, oligonucleotides (SEQ ID NOs 14-21) selec... | 06/11/1996 |
| 5516898 | Oligonucleotides for detecting bacteria and detection method using same Oligonucleotides (SEQ ID NOs 1-8) selectively hybridizable with a specific gene of Vibro parahaemolyticus, oligonucleotides (SEQ ID NOs 9-13) selectively hybridizable with the LT gene of toxigenic Escherchia coil, oligonucleotides (SEQ ID NOs 14-21) selec... | 05/14/1996 |
| 5472846 | Test kit and method for amplification and detection of antigen cells A test kit and method for the amplification and detection of specific antigen cells using a probe. The method includes reacting the probe-specific cells with enzyme-conjugated molecules to form separate molecules. The specific antigen cells are mixed with... | 12/05/1995 |
| 5393671 | Mutant Escherichia coli capable of enhanced L-glutamic acid production The present invention provides a mutant and discloses a process for producing L-glutamic acid by fermentation using a microorganism belonging to the genus Escherichia. The L-glutamic acid is produced and accumulated in a culture medium by culturing a muta... | 02/28/1995 |
| 5378616 | Mutant Escherichia coli capable of enhanced L-glutamic acid production by fermentation The present invention provides a mutant and a process for producing L-glutamic acid by fermentation using a microorganism belonging to the genus Escherichia. In the present process, L-glutamic acid is produced and accumulated in a culture medium by (A) cu... | 01/03/1995 |
| 5344762 | Method for the early diagnosis of cancer In a method for early diagnosis of human cancer, a human fecal sample of bacteria (Escherichia coli and/or Streptococcus faecalis), is incubated in vitro with a standard culture of a known number of cancer cells, for a period of time sufficient to enable ... | 09/06/1994 |
| 5338664 | Assay for detection of bacterial iron transport inhibitors The present invention relates to a method for identifying a TonB inhibitor in a test sample comprising: (a) growing a TonB+ microorganism in the presence of the test sample and a lethal agent, the activity of which is mediated by TonB; (b) identifyi... | 08/16/1994 |
| 5292644 | Rapid process for detection coliform bacteria A rapid process for detecting pathogenic microorganisms in products for human consumption comprises contacting the microorganisms with a methylumbelliferone substrate. The substrate is hydrolyzed into methylumbelliferone by an enzyme given off by the micr... | 03/08/1994 |
| 5264353 | Process for producing L-threonine by fermentation Microorganisms belonging to the genus Providencia or the genus Escherichia and having a resistance to isoleucine antagonist, produce L-threonine by fermentation in higher yield and in more amount of L-threonine accumulated.... | 11/23/1993 |
| 5221619 | Method and means for microbial polypeptide expression The Specification discloses: 1. Recombinant microbial cloning vehicles comprising heterologous DNA coding for the expression of mammalian hormone (e.g., somatostatin) and other polypeptides, including plasmids suited for the transformation of bacterial ho... | 06/22/1993 |
| 5143846 | Protease deficient bacterial hosts E. coli mutants which are capable of expressing cloned proteins in a highly stable manner are described.... | 09/01/1992 |
| 5128130 | Hybrid Bacillus thuringiensis gene, plasmid and transformed Pseudomonas fluorescens A novel hybrid B.t. toxin gene toxic to lepidopteran insects has been cloned. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express the B.t. toxin. These recombinant microbes can be used to control... | 07/07/1992 |
| 5066596 | Bacterial strains harboring cloned genes controlling Vibrio cholerae O-antigen biosynthesis The invention relates to a fragment of DNA containing genes encoding the synthesis of the O-antigen of Vibrio cholerae serotypes Inaba or Ogawa and being at least 16 kb in length. The invention further related to a cosmid comprising a cloned DNA fragment ... | 11/19/1991 |
| 5045469 | Novel bacillus thuringiensis isolate denoted B. T. PS81F, active against lepidopteran pests, and a gene encoding a lepidopteran-active toxin A novel B.t. toxin gene toxic to lepidopteran insects has been cloned from a novel lepidopteran-active B. thuringiensis microbe. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express the B.t. toxin... | 09/03/1991 |
| 5039523 | Novel Bacillus thuringiensis isolate denoted B.t. PS81F, active against lepidopteran pests, and a gene encoding a lepidopteran-active toxin A novel B.t. toxin gene encoding a protein toxic to lepidopteran insects has been cloned from a novel lepidopteran-active B. thuringiensis microbe. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to exp... | 08/13/1991 |
| 4987078 | Plasmid vectors for expression in Escherichia coli and/or Bacillus subtilis Novel plasmid vectors are described, for expression in Escherichia coli and/or Bacillus subtilis, in which the gene which codes for a heterologous protein is placed under the control of a promoter of the erythromycin gene which permit the organisms transf... | 01/22/1991 |
| 4978623 | Methods and compositions for expression of BTI endotoxin DNA sequences are provided coding for Bacillus thuringiensis var. israelensis (BTI) endotoxin, employing bacterial hosts which produce a protein having insecticidal activity for dipteran insects. The bacteriophage lambda strain SYN A4-1 was deposited at the A.... | 12/18/1990 |
| 4971794 | Production of antibodies using a mixture of strains of E. coli collectively expressing type I pili, CFA I pili, CFA II pili and K88 pili Antibodies are produced by hyperimmunizing a mammal, such as cow, with a vaccine derived from E. coli bacteria. The bacterial strains in the vaccine are selected on the basis of their virulence characteristics, especially adhesion factors (pili), associat... | 11/20/1990 |
| 4914025 | Export of intra-cellular substances An export sequence of export DNA can be identified by transforming a population of cells with a vector having a transposon that includes a structural gene encoding a detectable compound, positioned between insertion sequences. The structural gene encodes ... | 04/03/1990 |
| 4601986 | Protein product of reduced nucleic acid content and low allergenicity A nucleic acid-reduced substantially allergen-free single cell protein product is obtained by culturing a yeast, fungi or bacterium on an ultra-low sulfate medium, treating the produced cells with a base at a pH of about 9.5 with moderate heat, thereafter... | 07/22/1986 |
| 4599304 | Method for monitoring activated cell subpopulations A method of distinguishing multiple subpopulations of a cell sample whereby resting and activated human natural killer cells subpopulations can be monitored. This method utilizes two monoclonal antibodies identified as anti-Leu 11 and anti-DR (or anti-Leu... | 07/08/1986 |