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3M employee and church chorister Art Fry needed something to temporarily mark pages in his hymnal. He was in luck because his colleague, Spencer Silver, accidentally developed a glue that was too weak for other purposes. After initially discouraging consumer response, Post-it Notes became a hit in 1979.
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| Number | Title | Issue Date |
| 7115389 | Method for producing dipeptide A method for producing a dipeptide including the step of exposing a carboxy component and an amine component to an enzyme having an activity to hydrolyze amino acid ester. Such a hydrolase has been found among enzymes in bacteria. The method is useful for producing ... | 10/03/2006 |
| 6855561 | Method for adding an apparent non-signal line to a lateral flow assay A test device and method for determining the presence or absence of an analyte in a fluid sample, the test device including a support bearing a mark thereon, and a matrix defining an axial flow path. In operation, an observation area in the test device becomes trans... | 02/15/2005 |
| 6808703 | Lactobacillus KCTC 0774BP and acetobacter KCTC 0773BP for treatment or prevention of obesity and diabetes mellitus The present invention relates to microorganisms for the treatment or the prevention of obesity or diabetes mellitus, which reduce the amount of monosaccharide or disaccharide which may be absorbed into human body by converting monosaccharides such as glucose, fructo... | 10/26/2004 |
| 6541215 | Quantitative determination method of mannose and reagent therefor Disclosed are a method for quantitatively determining mannose, which comprises reacting mannose in a specimen with an enzyme which is capable of oxidizing the mannose by dehydrogenation, in the presence of an electron acceptor, and quantitatively determin... | 04/01/2003 |
| 6512014 | Compositions containing bioemulsifiers and a method for their preparation A bioemulsifier composition useful for forming and stabilizing oil-in-water emulsions, comprising an esterase protein of 32.5 KD, found in association with emulsan in the bacteria Acinetobacter. The esterase, or parts of it, are isolated from cell extract... | 01/28/2003 |
| 6429002 | Reticulated cellulose producing acetobacter strains Acetobacter strains are identified as stable under agitated culture conditions and exhibit substantially reduced gluconic and keto-gluconic acids production. A method and media for producing bacterial cellulose under agitated culture conditions resulting ... | 08/06/2002 |
| 6340582 | Process for preparing xylitol A method for producing xylitol by allowing a microorganism belonging to the Gluconobacter oxydans or Acetobacter xylinum and having a D-arabitol dehydrogenase activity and a D-xylulose reductase (xylitol dehydrogenase) activity and an ability to convert D... | 01/22/2002 |
| 6340457 | Pharmaceutical and alimentary compositions containing bacteria of genus acetobacter Pharmaceutical and alimentary compositions containing Acetobacter xylinum as the active ingredient for the treatment of gastroenteral dysmicrobisms, gastroenteral acute and chronic infections and impairments of the gastroenteral functionality.... | 01/22/2002 |
| 6329192 | Reticulated cellulose and methods of microorganisms for the production thereof A method and media for producing bacterial cellulose under agitated culture conditions resulting in sustained production over an average of 70 hours of at least 0.1 g/liter per hour are achieved. A unique reticulated cellulose product is produced using th... | 12/11/2001 |
| 6284243 | Physiologically functional food having brain function-improving, learning ability-enhancing, and memory-enhancing functions A physiologically functional food having brain function-improving, learning ability-enhancing and memory-enhancing functions, which comprises as an active ingredient a lactic acid bacterium fermented milk, a lactic acid bacterium and yeast co-fermented mi... | 09/04/2001 |
| 6153413 | Method for processing bacterial cellulose The purpose of the present invention is to provide a convenient method for restoring the various properties of BC even after it is once dried. The present invention relates to a method for processing a bacterial cellulose comprising dehydrating and drying unde... | 11/28/2000 |
| 6140105 | Cellulose-producing bacteria Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6×104 or above, one capable of producing a bacterial cellulose contain... | 10/31/2000 |
| 6110712 | Cellulose-producing bacteria This invention relates to a microorganism that is capable of producing a cellulosic product (referred to hereinafter as a "cellulose-producing bacterium") and belongs to a novel subspecies which is substantialy negative or very slightly positive in oxidat... | 08/29/2000 |
| 6048464 | Filter medium for leukocyte removal, method of making, and method of using thereof A leukocyte-removing filter material is described, which includes a porous element having fine pores of an average pore diameter of not less than 1.0 μm but less than 100 μm and a fiber structure composed of a plurality of fibers having an average fiber... | 04/11/2000 |
| 6017740 | Process for the production of bacterial cellulose The present invention relates to a process for the production of cellulosic material which comprises culturing a cellulose-producing bacterium while maintaining the internal pressure within the fermentation tank at about 1.1 kg/cm2 A or more, p... | 01/25/2000 |
| 5962278 | Cellulose-producing bacteria This invention relates to a microorganism that is capable of producing a cellulosic product (referred to hereinafter as a "cellulose-producing bacterium") and belongs to a novel subspecies which is substantialy negative or very slightly positive in oxidat... | 10/05/1999 |
| 5951910 | Reticulated bacterial cellulose as a rheological modifier for polyol fluid compositions Rheologically modified compositions, and rheologically modified fluid compositions prepared therefrom, containing reticulated bacterial cellulose in a polyol base fluid, are disclosed. The amount of reticulated bacterial cellulose present in the compositi... | 09/14/1999 |
| 5871978 | Method of producing reticulated cellulose having type II crystalline cellulose A method and media are provided for producing bacterial cellulose under agitated culture conditions resulting in sustained production over an average of 70 hours of at least 0.1 g/liter per hour are achieved. A unique reticulated cellulose product is prod... | 02/16/1999 |
| 5846213 | Cellulose membrane and method for manufacture thereof Cellulose films useful as wound and bum dressings are prepared from a solution of cellulose produced by Acetobacter xylinum in a stirred tank. The materials of this invention comprise a film of microbially produced cellulose, particularly cellulose produc... | 12/08/1998 |
| 5821109 | Reticulated cellulose and methods and microorganisms for the production thereof A method and media for producing bacterial cellulose under agitated culture conditions resulting in sustained production over an average of 70 hours of at least 0.1 g/liter per hour are achieved. A unique reticulated cellulose II product is produced using... | 10/13/1998 |
| 5792630 | Cellulose-producing microorganism transformed with a gene for an enzyme involved in sucrose metabolism A method for the production of a cellulosic product, which comprises: culturing a cellulose-producing microorganism transformed with a gene for an enzyme involved in sucrose metabolism in a medium containing sucrose, allowing the cellulosic product to be produ... | 08/11/1998 |
| 5747301 | D-sorbitol dehydrogenase A D-sorbitol dehydrogenase in homogenous form, which catalyzes the oxidation of D-sorbitol to L-sorbose, has a molecular structure consisting of homologous subunits of molecular weight 79,000&#b1;5,000 each, a substrate specificity for polyols and an opti... | 05/05/1998 |
| 5731173 | Fructosyltransferase enzyme, method for its production and DNA encoding the enzyme Extracellular fructosyltransferase of Acetobacter diazotrophicus was isolated and purified and its enzymatic properties were established. Cloning, sequencing and genetic manipulation of the fructosyltransferase gene so as to produce high levels of the enz... | 03/24/1998 |
| 5672504 | Process for enriching an R,S!-1,2-epoxide in one enantiomer by using microbes to convert one enantiomer to the other or to preferentially open the epoxide ring A microorganism or a preparation thereof is permitted to act on a mixture of enantiomers of an epoxide such as 3-chlorostyrene oxide and the product optically active epoxide is recovered. The microorganism able to produce an optically active (S)-epoxide f... | 09/30/1997 |
| 5624812 | Method for measuring carbon dioxide and reagent therefor A method for measuring carbon dioxide, comprising the steps of: (1) reacting bicarbonate ion in a sample with phosphoenolpyruvate carboxylase derived from an acetic acid bacterium in the presence of phosphoenolpyruvate; (2) reacting the resultant oxalacet... | 04/29/1997 |
| 5578474 | Process for culturing recombinant microorganisms A recombinant microorganism strain having a desired metabolic property is produced by a process which utilizes a multiple chemostat system.... | 11/26/1996 |
| 5547851 | Method for measuring carbon dioxide and reagent therefor A method for measuring carbon dioxide, comprising the steps of: (1) reacting bicarbonate ion in a sample with phosphoenolpyruvate carboxylase derived from an acetic acid bacterium in the presence of phosphoenolpyruvate; (2) reacting the resultant oxalacet... | 08/20/1996 |
| 5494580 | Method of decontamination of a hydrocarbon-polluted environment by the use of bacterial compositions Method of decontamination of a hydrocarbon-polluted environment by the use of bacterial compositions. The method is a process of biological decomposition of the hydrocarbons using, as decontaminating active ingredients, bacterial compositions composed of ... | 02/27/1996 |
| 5484725 | Norbornane type ester hydrolase from Acetobacter pasteurianus A norbornane type ester hydrolase that enantio-selectively hydrolyzes a (&#b1;)-exo-norbornane type ester represented by Formula I is provided: ##STR1## wherein R is acyl, and A and B are hydrogens, respectively, or where A and B are absent, resultin... | 01/16/1996 |
| 5484715 | Method for preparing an antitumor dextran using a dextran synthetase from Lactobacillus confusus A method is provided for preparing an antitumor dextran by contacting a culture broth containing sucrose with an antitumor dextran obtained from Lactobacillus confusus and collecting the antitumor dextran from the culture broth. The enzyme can be used as ... | 01/16/1996 |
| 5468627 | Process of preparing butyric acid or 2- or 3-methylbutyric acid by oxidizing the corresponding butanols with gluconobacter roseus IAM 1841 or IFO 3990 Disclosed is a process for the preparation of aliphatic carboxylic acids by microbial oxidation of alcohols with relatively long, optionally branched C chains by means of atmospheric oxygen, in which the bacteria species Gluconobacter roseus is used as th... | 11/21/1995 |
| 5459067 | Method for producing optically active norborneol by ester hydrolysis A method for producing an optically active norborneol is provided, which includes the step of bringing a microorganism or treated cells thereof into contact with (&#b1;)-exo-norbornane type ester represented by Formula (I), wherein the microorganism is se... | 10/17/1995 |
| 5424201 | Method for preparing an antitumor dextran using Lactobacillus confusus Lactobacillus confusus strains capable of producing a dextran which has biological activities such as an excellent antitumor activity, etc. are disclosed. Also disclosed is a method for producing said dextran using said microorganism or dextran synthetase... | 06/13/1995 |
| 5382656 | Cellulose synthase associated proteins Novel proteins capable of binding to bacterial cellulose synthase are provided. Proteins that co-purify with bacterial cellulose synthase and have approximate relative molecular weights of 20 kDa, 54 kDa and 59 kDa are taught. Also provided for are nucleo... | 01/17/1995 |
| 5360723 | Method for lowering molecular weight of microbial celluloses Provided is a method for controlling the molecular weight (i.e., lowering) of microbially-derived celluloses. The lowering of the molecular weight is achieved by adding 2-deoxy-D-glucose to the liquid or solid medium in which Acetobacter xylinum or any ot... | 11/01/1994 |
| 5344777 | Structural gene of membrane-bound alcohol dehydrogenase complex, plasmid containing the same and transformed acetic acid bacteria There is provided a structural gene of membrane-bound alcohol dehydrogenase complex having a molecular size of about 7.0 kilo base which is derived from a microorganism belonging to the genus Acetobacter represented by Acetobacter altoacetigenes and shown... | 09/06/1994 |
| 5326702 | Biological process for producing -hydroxyamide or -hydroxy acid A process for biologically producing an -hydroxyamide or an -hydroxy acid represented by formula (III) ##STR1## wherein R represents a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group, a substituted... | 07/05/1994 |
| 5312741 | Process for producing 2-keto-L-gulonic acid The present invention relates to a process for producing 2-keto-L-gulonic acid by fermentative conversion of D-sorbitol in high yield. 2-Keto-L-gulonic acid is an important intermediate for the production of L-ascorbic acid into which it can be converted.... | 05/17/1994 |
| 5273891 | Process for the production of microbial cellulose A process for the production of extra-cellular microbial cellulose in which a novel strain of the genus Acetobacter capable of producing extra-cellular microbial cellulose is aerobically cultivated in an aqueous culture medium containing a carbon source a... | 12/28/1993 |
| 5268274 | Methods and nucleic acid sequences for the expression of the cellulose synthase operon Nucleic acid sequences encoding the bacterial cellulose synthase operon derived from Acetobacter are disclosed. Methods for isolating the genes, vectors containing the genes, and transformed hosts useful for the expression of recombinant bacterial cellulo... | 12/07/1993 |
