Did You Know...
...that to encourage use of his new invention, the shopping cart, market owner Sylvan Goldman hired fake shoppers to push the carts around his store in Oklahoma City? Seems his customers were reluctant to give up their hand-carried baskets.
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| Number | Title | Issue Date |
| 7238537 | Assays An analytical test device incorporating a dry porous carrier to which a liquid sample, eg. urine, suspected of containing an analyte such as HCG or LH can be applied indirectly, the device also incorporating a labelled specific binding reagent which is freely mobile... | 07/03/2007 |
| 6844164 | Antibody against rat postacrosome reaction sperm and utilization thereof An antibody biding specifically to rat's acrosome reacted sperm is produced and hybridomas (FARS-91 and FARS-92 strains) capable of stably proliferating are obtained by fusing mouse spleen cells having a high antibody titer against rat's acrosome reacted sperm with ... | 01/18/2005 |
| RE38688 | Sheet-like diagnostic device A solid diagnostic device for the quantitative determination of substances of biological affinity in biological fluids is described. A process is also described in which the biological fluid is brought into contact with a specific functional sector of the device, th... | 01/18/2005 |
| 6716812 | Modulation of sperm function The hormone calcitonin promotes fertilizing ability in mammalian sperm and is useful for treatment of conditions of low fertility in humans and animals. Human, porcine or salmon calcitonin may be formulated in a pharmaceutical composition comprising a pharmaceutical... | 04/06/2004 |
| 6602676 | Testing method This invention relates to a method of predicting pregnancy, particularly, in a cow, the method comprising taking a milk sample from the cow in which a milk progesterone concentration of >3 ng ml-1 by Day 4 post insemination is indicative that t... | 08/05/2003 |
| 6541206 | Objective biochemical method for assessment of sperm quality A method of testing sperm quality including obtaining a sample of sperm to be tested; detecting and measuring the testis-specific HspA2 chaperone protein (or, the chaperone protein homologues to HspA2) in human and animal sperm; and determining a sperm qu... | 04/01/2003 |
| 6429018 | Prenatal screening for Down's syndrome using hyperglycosylated gonadotropin A prenatal screening method for Down's syndrome involves assaying for hyperglycosylated gonadotropin in biological test samples such as urine, plasma or serum obtained from pregnant women. Hyperglycosylated gonadotropin comprises a variant population of c... | 08/06/2002 |
| 6352862 | Analytical test device for imuno assays and methods of using same An analytical test device incorporating a dry porous carrier to which a liquid sample, eg. urine, suspected of containing an analyte such as HCG or LH can be applied indirectly, the device also incorporating a labelled specific binding reagent which is fr... | 03/05/2002 |
| 6258525 | Method and kit for detecting infertility Methods for labeling mannose lectins on the surface of mammalian sperm cells are described, and methods of categorizing and quantifying the numbers of cells exhibiting particular labeling patterns are also provided. These methods provide ways of detecting... | 07/10/2001 |
| 6207382 | Production of lampbrush chromosome A process for inducing a transcriptionally active chromosome (i.e., a "lampbrush" chromosome) from condensed chromatin or nucleus is disclosed. The condensed chromosome is contacted with the contents of a germinal vesicle. Preferably, the nuclear envelope... | 03/27/2001 |
| 6172198 | PAPP-A, its immunodetection and uses This invention concerns PAPP-A, its immunodetection and the clinical benefits of such immunodetection. Specifically, the invention includes monoclonal antibodies against PAPP-A and the use of these antibodies to detect PAPP-A at a very early stage of preg... | 01/09/2001 |
| 5981291 | Estrogen marker system A method for evaluating the solubility capacity of free unbound estrogens in body fluids of animals is described.... | 11/09/1999 |
| 5981198 | Preimplantation factor A factor that indicates fertilization of an ovum before implantation, Preimplantation Factor (PIF), has been found. PIF also provides an early indication of pregnancy, malignancy, and autoimmune diseases. Assays for PIF are described. Detection of PIF in ... | 11/09/1999 |
| 5972594 | Method for screening for reproductive tract inflammation and preeclampsia using neutrophil defensins A method and apparatus for screening for reproductive tract inflammation and preeclampsia which utilizes the increase in neutrophil defensins to indicate that a patient is at risk of having reproductive tract inflammation or preeclampsia. The apparatus co... | 10/26/1999 |
| 5935800 | Assays and kits for determining male fertility Assays and kits for identifying fertile sperm samples (e.g. for use in an assisted reproductive technology or as an indication of an ineffective male contraception (vasectomy)) and sub-fertile sperm samples (e.g. as an indication of a potentially infertil... | 08/10/1999 |
| 5932431 | Determination of steroids by competitive immunoassay A method and kit for measurement of a steroid by means of a competitive immunoassay, preferably a competitive enzyme immunoassay. The method and kit involve the use of a steroid analogue conjugated to a label. The steroids that are amenable to detection b... | 08/03/1999 |
| 5922613 | Method for evaluating estrogen dependent physiological conditions A method and apparatus for evaluating estrogen dependent physiological conditions includes a substrate having an anthocyanin pigment applied thereto. The pigment yields a color response indicative of how the body fluid responds to changes in its capacity ... | 07/13/1999 |
| 5919621 | Methods for diagnosing human male infertility A method for determining the capacity of a human sperm to fertilize a human egg is described by assessing sperm activation events in an in vitro assay using a non-mammalian egg extract, particularly a Xenopus laevis frog egg extract. Fertilizing capacity ... | 07/06/1999 |
| 5895749 | Male fertility and contraception home test kits Kits and assays, incorporating antibodies specific for glutathione peroxidase, for determining the fertilizing ability of a male at home or in a clinical laboratory are disclosed.... | 04/20/1999 |
| 5866354 | Method for measuring mobility of sperm A method of identifying highly fecund males in which an isotonic, buffered liquid test specimen of semen is layered on top of a barrier medium that inhibits net movement (migration) of less mobile sperm into the barrier medium. Differences in mobility of ... | 02/02/1999 |
| 5849713 | Chemotactic factors for human spermatozoa and their use in human assisted fertilization The invention relates to chemotactic factors for human spermatozoa that are purifiable from human follicular fluid. The factors are of peptidic and hydrophilic nature and have, one, a molecular size of about 13 kDa and, the other, an apparent molecular si... | 12/15/1998 |
| 5843673 | Method of screening for endometriosis A glycoprotein having a molecular weight of 28,000 to 32,000 and an isoelectric point of 7.0 to 9.0, both as determined by two-dimensional SDS polyacrylamide gel electrophoresis, is synthesized and secreted specifically by stromal cells of endometriotic o... | 12/01/1998 |
| 5834317 | Method for antenatal risk assessment for fetal abnormalities using gestational age discrepancy A method for antenatal screening for chromosomal and other abnormalities in an unborn child is determined by measuring the gestational age discrepancy of the pregnant mother. This data is determined (a) by reference to the last menstrual period, and (b) a... | 11/10/1998 |
| 5801058 | Analytic method to determine the fertilizing capacity of a human semen sample The invention relates to improvements in determining the fertilizing capacity of a human semen sample using a reagent solution which contains 0.1-5% by weight K2 PO4 H/KPO4 H2 to adjust the pH of the solution to... | 09/01/1998 |
| 5763206 | Process for evaluating fertility of spermatozoa samples A method for testing the potential fertility of spermatozoa in a sample by contacting an aliquot of the sperm sample onto a protein extracted from native vitelline membranes removed from chicken or turkey eggs to enable quantification of the number of spe... | 06/09/1998 |
| 5723305 | Marker for male infertility and/or fertility The present invention relates to a method for the diagnosis of male infertility which comprises the steps of a) determining the amount of P34H in a sperm sample; and b) comparing the determined amount of step (a) with a fertile control sample. The present... | 03/03/1998 |
| 5693479 | Fertility determination with transforming growth factor ଲ Therapeutic and diagnostic methods of use for the growth factor transforming growth factor ଲ, are provided by this invention. In accordance with preferred embodiments, methods of determining competence of a conceptus toward uterine implantation are ... | 12/02/1997 |
| 5665556 | Complement components and binding ligands in fertility Methods for detecting and isolating acrosome-reacted sperm and complement receptor-bearing oocytes using the complement component C3, fragments, or variants thereof, antibodies to a complement receptor, or antibodies to C3, are disclosed. These methods ha... | 09/09/1997 |
| 5663054 | Determination of steroids by competitive immunoassay A method and kit for measurement of asteroid by means of a competitive immunoassay, preferably a competitive enzyme immunoassay. The method and kit involve the use of asteroid analogue conjugated to a label. The steroids that are amenable to detection by ... | 09/02/1997 |
| 5660997 | Methods for determining antibodies specific for sex associated sperm membrane proteins Substantially pure sex-associated membrane (SAM) proteins are used in methods to detect specific antibodies binding to X- or Y-SAM proteins.... | 08/26/1997 |
| 5646003 | Preimplantation factor A factor that indicates fertilization of an ovum before implantation, Preimplantation Factor (PIF), has been found. PIF also provides an early indication of pregnancy, malignancy, and autoimmune diseases. Assays for PIF are described. Detection of PIF in ... | 07/08/1997 |
| 5635366 | Predictive assay for the outcome of IVF The present invention provides a method for predicting the outcome of IVF which comprises: (i) determining the level of 11ଲ-hydroxysteroid dehydrogenase (11ଲ-HSD) in a biological sample from a female patient; and (ii) predicting from the level of 1... | 06/03/1997 |
| 5618680 | Use of ligands specific to major histocompatibility complex-class I antigens for diagnosing endometriosis It is an object of the present invention to provide the clinicians with a new application for ligands specific to MHC-class I antigens, especially HLA-ABC antigens, this new application residing in the detection and diagnosis of endometriosis. It is also ... | 04/08/1997 |
| 5599680 | Diagnostic applications of mouse ascites golgi (MAG) manipulation Therapeutic and diagnostic applications by the detection and manipulation of mouse ascites golgi factor produced by endometrium and present in other exocrine tissues and defined by an antibody found in mouse ascites are provided by this invention.... | 02/04/1997 |
| 5575914 | Sperm filter trap having compressed glass wool filter material A filter trap (10) for removing spermatozoa of relatively lower viability from a fluid containing both higher and lower viability spermatozoa includes a conduit (14) which compresses silica glass wool (16) to a density adequate to prevent the passage ther... | 11/19/1996 |
| 5569581 | Alteration and prediction of male fertility using seminal plasma and its components Two-dimensional polyacrylamide gel electrophoresis of seminal plasma samples indicate that two proteins (26 kDa, pI 6.2; 55 kDa, pI 4.5) predominated in higher fertility bulls and two proteins (16 kDa, pI 4.1; 16 kDa, pI 6.7) predominated in lower fertili... | 10/29/1996 |
| 5474927 | Complement components and binding ligands in fertility Methods for detecting and isolating acrosome-reacted sperm and complement receptor-bearing oocytes using the complement component C3, fragments, or variants thereof, antibodies to a complement receptor, or antibodies to C3, are disclosed. These methods ha... | 12/12/1995 |
| 5434057 | Sperm motility assay and devices The present invention provides devices, methods and kits for assessing fertility potential of semen samples. Semen samples may be assayed by the present invention to identify those samples having more than 20×106 motile sperm per milliliter, a... | 07/18/1995 |
| 5424193 | Assays employing dyed microorganism labels The present invention relates generally to test articles and assays for the detection of analytes in biological fluid samples. More particularly, the present invention relates to test articles an assays which employ dyed microorganisms as visual labels to... | 06/13/1995 |
| 5412148 | Amplifier molecules derived from diethylene triaminepentaacetic acid for enhancement of diagnosis and therapy Disclosed are amplifier molecules: various organic compounds having branched structures terminating with amine groups to which pharmacologically active groups can be chemically attached. A number of MRI contrast-enhancing agents were synthesized, each com... | 05/02/1995 |
