Bizarre Patents
A new toilet tank assembly aquarium for housing aquatic creatures.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7569364 | Anti-NGF antibodies and methods using same The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgic... | 08/04/2009 |
| 7524650 | Antibodies directed against hepatitis C virus E1E2 complex, compositions of HCV particles, and pharmaceutical compositions New conformational antibodies are directed against HCV and more particularly to monoclonal antibodies. Described compositions of particles are liable to be recognized by the antibodies, as are pharmaceutical compositions containing them. Also described are HCV envel... | 04/28/2009 |
| 7442550 | Method for detecting the expression of an envelope protein of a human endogenous retrovirus and uses of a gene coding for said protein A method for detecting the expression of a polypeptide in cells and for detecting the interaction between a polypeptide and cells, ex vivo or in vitro, wherein the polypeptide is selected from the group consisting of: a peptide comprising the cyt domain of the envel... | 10/28/2008 |
| 7435553 | Isolating cells expressing secreted proteins A method of detecting and isolating cells that produce any secreted protein of interest (POI), comprising: a) constructing a cell line transiently or stably expressing a cell surface capture molecule, which binds the POI, by transfecting the cell line with a nucleic... | 10/14/2008 |
| 7427669 | ULBP antibodies The invention is directed to purified and isolated novel ULBP polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived... | 09/23/2008 |
| 7410771 | Reagent and method for detecting a sporozoite antigen A reagent and method for the specific and highly sensitive detection of C. parvum in which the reagent is an antibody for a soluble C. parvum sporozoite antigen and the method is an immunoassay in which the antibody is used to detect or quantify C. ... | 08/12/2008 |
| 7342105 | Antibody and use thereof The antibody of the present invention, which specifically reacts with the N-terminal or C-terminal partial peptide of TGR23-2 ligand, is useful in detecting and quantifying the TGR23-2 ligand. Moreover, it is useful as a preventing/treating agent and a diagnostic ag... | 03/11/2008 |
| 7285288 | Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides The present invention provides novel compositions and methods for use in the treatment of Bcl-2-associated diseases like cancer, specifically, in the treatment of follicular lymphoma (FL). The compositions contain antisense oligonucleotides that hybridize to Bcl-2 n... | 10/23/2007 |
| 7220559 | Development of human monoclonal antibodies and uses thereof This invention provides: a heteromyeloma, other than B6B11, capable of producing a trioma when fused with a human lymphoid cell, wherein the trioma is capable of producing a monoclonal antibody-secreting tetroma when fused with a second, antibody-secreting human lym... | 05/22/2007 |
| 7196175 | Antibodies to JTT-1 protein and cells secreting such antibodies Novel cell surface molecules recognized by monoclonal antibodies against a cell surface molecule of lymphocytic cells that play an important role in autoimmune diseases and allergic diseases have been isolated, identified, and analyzed for their functions. The cell ... | 03/27/2007 |
| 7193058 | ULBP antibodies The invention is directed to purified and isolated novel ULBP polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived... | 03/20/2007 |
| 7169578 | Cell isolation and screening device and method of using same The present invention provides methods and devices for screening a single cell or a small group of cells for a desired biological activity. In particular, the present invention provides for delivering cell(s) to a plurality of cell isolation regions of a cell isolat... | 01/30/2007 |
| 7169577 | Cell isolation and screening device and method of using same The present invention provides methods and devices for screening a single cell or a small group of cells for a desired biological activity. In particular, the present invention provides for delivering cell(s) to a plurality of cell isolation regions of a cell isolat... | 01/30/2007 |
| 7163819 | Bacterial hemoglobin genes and their use to increase carotenoid production Genes encoding bacterial oxygen binding proteins are provided. Recombinant expression of at least one of the present bacterial hemoglobin genes increased the growth characteristics and/or carotenoid production levels in microbial host cells grown under microaerobic ... | 01/16/2007 |
| 7157257 | Method of treating biological cells and/or their cell components with electrical fields A method is described for treating biological cells and/or their cell components with electrical fields in a reaction medium, in which an inhibitor is added to the reaction medium to counteract the action of enzymes that break down protein. ... | 01/02/2007 |
| 7148040 | Method of rapid production of hybridomas expressing monoclonal antibodies on the cell surface The present invention relates to genetically altered hybridomas, myelomas and B cells. The invention also relates to utilizing genetically altered hybridomas, myelomas and B cells in methods of making monoclonal antibodies. The present invention also provides popula... | 12/12/2006 |
| 7118889 | Protein tyrosine kinase substrate LAT and its use in the indentification of (ant)agonists of the kinase The invention generally relates to compositions and methods for identifying and testing tyrosine kinase signaling pathway agonists and antagonists, and more particularly, methods and compositions for screening compounds and identifying compounds that will modulate t... | 10/10/2006 |
| 7109309 | Peptide fructose and protein conjugate with the same It is intended to provide an antibody specific to HbA1c, antibody-producing cells capable of supplying the antibody in a stable state in the future, and a method of constructing the antibody-producing cells without any probability factors, and a method which compris... | 09/19/2006 |
| 7109003 | Methods for expressing and recovering human monoclonal antibodies to CTLA-4 In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucelotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, ... | 09/19/2006 |
| 7094400 | Transkaryotic implantation The present invention provides a method of altering the concentration or level of expression of a desired gene product in a recipient subject which involves administering to a recipient a transkaryotic cell capable of expressing a desired gene when the cell is prese... | 08/22/2006 |
| 7081348 | Immunoassay of human medullasin and diagnosis of multiple sclerosis using the same There is provided an immunoassay by which the amount of human medullasin present inside granulocytes, which are one leukocyte component in blood, can be determined with high accuracy and with good reproducibility. Also provided is an immunoassay of medullasin, where... | 07/25/2006 |
| 7067268 | Antibodies and utilization thereof The anti-19P2 ligand monoclonal antibodies of the invention (in particular P2L-1Ca) have very high binding ability and can neutralize the arachidonic acid metabolite releasing activity of the 19P2 ligand. Therefore, they can be used, among others, as diagnostic, pro... | 06/27/2006 |
| 7060276 | AMA-1 protein and uses thereof In this application is described the expression and purification of a recombinant Plasmodium falciparum (3D7) AMA-1 ectodomain. The method of the present invention produces a highly purified protein which retains folding and disulfide bridging of the native m... | 06/13/2006 |
| 7056702 | Detecting lipocalin The invention provides antibodies reactive with distinct lipocalin epitopes that are useful for detecting inflammation and bacterial infections in mammals. ... | 06/06/2006 |
| 6977244 | Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides The present invention provides novel compositions and methods for use in the treatment of Bcl-2-associated diseases like cancer, specifically, in the treatment of follicular lymphoma (FL). The compositions contain antisense oligonucleotides that hybridize to Bcl-2 n... | 12/20/2005 |
| 6962695 | Modification of interferon alpha production A process for the production of α-interferon comprising the steps: i) inducing of human leukocytes by means of a virus; ii) treating the leukocytes with an enhancing agent selected from: a) Xanthine, pyrimidinol and pyrimidinone or derivatives of anyone thereof, su... | 11/08/2005 |
| 6919183 | Isolating cells expressing secreted proteins A method for identifying and isolating cells which produce secreted proteins. This method is based upon a specific characteristic or the expression level of the secreted protein by transiently capturing the secreted protein on the surface of an individual cell, allo... | 07/19/2005 |
| 6863892 | Nucleic acid and corresponding protein named 158P1D7 useful in the treatment and detection of bladder and other cancers A novel gene (designated 158P1D7) and its encoded protein are described. While 158P1D7 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in multiple cancers including set forth in Table 1. Consequently, 158P1D7 provides a diagnos... | 03/08/2005 |
| 6846667 | Virulence genes and proteins, and their use The present invention is based on the identification of a series of virulence genes in E. coli K1, the products of which may be implicated in the pathogenicity of the organisms. The identification of the genes allows them, or their expressed products, to be u... | 01/25/2005 |
| 6844164 | Antibody against rat postacrosome reaction sperm and utilization thereof An antibody biding specifically to rat's acrosome reacted sperm is produced and hybridomas (FARS-91 and FARS-92 strains) capable of stably proliferating are obtained by fusing mouse spleen cells having a high antibody titer against rat's acrosome reacted sperm with ... | 01/18/2005 |
| 6767709 | Immunoassay of human medullasin and diagnosis of multiple sclerosis using the same There is provided an immunoassay by which the amount of human medullasin present inside granulocytes, which are one leukocyte component in blood, can be determined with high accuracy and with good reproducibility. Also provided is an immunoassay of medullasin, where... | 07/27/2004 |
| 6733997 | Isolated nucleic acids encoding a secretory signal for expression and secretion of heterologous recombinant proteins A universal secretory signal originally derived from a piscine vitellogenin (Vtg) gene is inserted into various expression vectors for driving the secretion of the recombinant protein into the culture medium. This enhances the detection, quantification and downstrea... | 05/11/2004 |
| 6709873 | Method for production of antibodies to specific sites of rapamycin This invention relates to the production of polyclonal and monoclonal antibodies to specific sites of rapamycin (Sirolimus). The reactivity of these poly and monoclonal antibodies make them particularly useful for immunoassays for therapeutic drug monitoring (TDM). ... | 03/23/2004 |
| 6689360 | Human B-cell translocation genes-2 and 3 antibodies The present invention relates to antiproliferative genes. More specifically, isolated nucleic acid molecules are provided encoding the human B-cell translocation genes 2 and 3 (BTG-2 and BTG-3). BTG-2 and BTG-3 polypeptides are also provided, as are vecto... | 02/10/2004 |
| 6689604 | Lipopolysaccharide -2,3 sialyltransferase of Campylobacter jejuni and its uses The structure and specificity of a recombinant 댒,3-sialyltransferase from Campylobacter spp., is disclosed. Also provided are methods for using the 댒,3-sialyltransferase in the production of desired carbohydrate structures and nucleic acids ... | 02/10/2004 |
| 6660501 | Production of proteins by cell culture A process for the production of a protein by cell culture, where the cells that produce the protein are cultured in the presence of a chemical agent that enhances the production of the protein.... | 12/09/2003 |
| 6649421 | Antibodies against phoshorylated VASP (vasodilator-stimulated phosphoprotein), hybridoma cells for their preparation, and their use The invention relates to antibodies against VASP (vasodilator-stimulated phosphoprotein) which only bind VASP as an antigen when VASP is present in phosphorylated form, to hybridoma cells for their preparation, and to the use of the antibodies or antibody... | 11/18/2003 |
| 6632976 | Chimeric mice that are produced by microcell mediated chromosome transfer and that retain a human antibody gene A chimeric, non-human animal can be produced by a method that entails providing a microcell that contains one or more foreign chromosomes or fragment(s) thereof and then fusing the microcell with a pluripotent cell, thereby introducing the foreign chromos... | 10/14/2003 |
| 6630327 | Methods and reagents for preparing and using immunological agents specific for P-glycoprotein This invention relates to immunological reagents and methods specific for a mammalian, transmembrane protein termed Pgp, having a non-specific efflux pump activity established in the art as being a component of clinically-important multidrug resistance in... | 10/07/2003 |
| 6593109 | Recombinant bone morphogenetic protein heterodimers, compositions and methods of use The present invention relates to a methods for producing recombinant heterodimeric BMP proteins useful in the field of treating bone defects, healing bone injury and in wound healing in general. The invention also relates to the recombinant heterodimers a... | 07/15/2003 |
