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Vehicular Impact Signaling Device
An apparatus for the deployment of a visible plume to alert other motorists that a proximate motor vehicle has been involved in a collision.
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| Number | Title | Issue Date |
| 7625718 | SVCT2 transporters expressed in blood brain barrier cells SVCT2 is consistently expressed at high levels in brain microvessel endothelial cells. Disclosed herein are assays for determining whether a test material/molecule is a substrate for, and/or is actively transported by, the SVCT2 transporter, and therefore a candidat... | 12/01/2009 |
| 7611858 | Detection of cannabinoid receptor biomarkers and uses thereof Traumatic insult to the brain leads to a degradation of low molecular weight of cannabinoid type 1 receptor (CB1) and generation of high molecular weight complexes in the cortex and hippocampus, as assessed by both N-terminal and C-terminal specific antibodies. The ... | 11/03/2009 |
| 7608414 | Method for diagnosing and prognosing inflammatory bowel disease and crohn's disease Disclosed are methods for diagnosing and prognosing Inflammatory Bowel disease or Crohn's disease (CD) by measuring levels of antibodies to glycans in a biological sample. ... | 10/27/2009 |
| 7592150 | Method for diagnosing diseases based on levels of anti-glycan antibodies Disclosed are methods for diagnosing Crohn's disease (CD) or anti-phospholipid syndrome by measuring levels of antibodies to glycans in a biological sample. ... | 09/22/2009 |
| 7563587 | Method and kit for cell analyte assay The present invention relates to a method for analysing a cell sample for cell surface-bound or intracellularly bound analytes by providing an array of immobilised specific binding agents for a set of different ligands, where each ligand is specific to a respective ... | 07/21/2009 |
| 7537908 | Methods of diagnosing sepsis by measuring HMG1 There is disclosed a pharmaceutical composition and method for treating sepsis, including septic shock and ARDS (acute respiratory distress syndrome), comprising administering an effective amount of a HMG1 antagonist. There is further disclosed a diagnostic method f... | 05/26/2009 |
| 7442516 | Antibody specific to central nervous system tau protein The present invention provides an antibody which specifically recognizes a CNS tau protein but not a peripheral tau protein. More specifically, the present invention provides an antibody obtainable by using a polypeptide comprising an amino acid sequence of a connec... | 10/28/2008 |
| 7442514 | Mutants of the factor VII-activating protease and detection methods using specific antibodies Mutants of the DNA sequence coding for the protease (FSAP) which activates blood clotting factor VII and single-chain plasminogen activators, the mutants comprising a G/C base exchange at nucleotide position 1177 and/or a G/A base exchange at nucleotide position 160... | 10/28/2008 |
| RE40535 | Anti-KC4 humanized monoclonal antibody and cells that express the antibody An anti-KC-4 humanized monoclonal antibody that comprises the variable regions of the light and heavy chains of the anti-KC-4 murine antibody, wherein the light chain has 7 amino acids and the heavy chain has 12 amino acids of the framework regions substituted with ... | 10/07/2008 |
| 7432105 | Self-calibration system for a magnetic binding assay A self-calibrated, magnetic binding assay (e.g., sandwich, competitive, etc.) for detecting the presence or quantity of an analyte residing in a test sample is provided. The magnetic binding assay includes detection probes capable of generating a detection signal (e... | 10/07/2008 |
| 7429458 | Methods of using bioelastomers Bioelastomers are disclosed for use in methods of binding compounds including immunoassay methods, in biosensors and methods or regenerating biosensors, and in methods for targeting the delivery of a compound to a particular location within an animal subjects. In ge... | 09/30/2008 |
| 7429643 | POSH nucleic acids, polypeptides and related methods The application discloses novel polypeptides and nucleic acids involved in a variety of biological processes, including viral reproduction. Related methods and compositions are also described. ... | 09/30/2008 |
| 7416855 | Immunoassay methods for detecting interleukin-1 β converting enzyme like apoptosis protease-3 Disclosed are human interleukin-1 β converting enzyme like apoptosis proteases-3 and 4 and DNA (RNA) encoding such polypeptides. Also provided is a procedure for producing such polypeptides by recombinant techniques and antibodies and antagonists against such polyp... | 08/26/2008 |
| 7410771 | Reagent and method for detecting a sporozoite antigen A reagent and method for the specific and highly sensitive detection of C. parvum in which the reagent is an antibody for a soluble C. parvum sporozoite antigen and the method is an immunoassay in which the antibody is used to detect or quantify C. ... | 08/12/2008 |
| 7393653 | Methods of modulating cell death based on the Bit1/AES regulatory pathway The present invention provides a method of identifying an effective agent that alters the association of a Bit1 polypeptide with an AES polypeptide. The method is practiced by contacting a Bit1 polypeptide, or active fragment thereof, and an AES polypeptide, or acti... | 07/01/2008 |
| 7393647 | Methods for detecting infection This invention pertains to methods for detecting B. anthracis and antibodies to B. anthracis, the causative agent of anthrax, in a subject. ... | 07/01/2008 |
| 7390626 | Methods and kit for diagnosing tick borne illnesses ELISA, Western Blot, and a peptide-based ELISA were applied to clinical specimens from patients with clinical symptoms of tick borne diseases, including Lyme disease. Peptides from different components of Borrelia during different cycles, including peptides f... | 06/24/2008 |
| 7390627 | Assays, antibodies, and standards for detection of oxidized and MDA-modified low density lipoproteins Immunoassays for malondialdehyde-modified low density lipoprotein (MDA-modified LDL) and oxidized low density lipoprotein (OxLDL), monoclonal antibodies (and the cell lines for them) for use in the assays, and a storage-stable standard (which may be used as a calibr... | 06/24/2008 |
| 7374888 | Methods for detecting infection This invention pertains to methods for detecting B. anthracis and antibodies to B. anthracis, the causative agent of anthrax, in a subject. ... | 05/20/2008 |
| 7371534 | Sensitive intracellular calcium assay A sensitive intracellular calcium assay is disclosed comprising conveniently a reagent comprised of a dye precursor capable of entering cells and being hydrolyzed to a dye, whereby the dye complexes with calcium in the cells and provides a luminescent signal, an ant... | 05/13/2008 |
| 7368277 | Method for assay of antibodies and antibody assay device The invention relates to a technology by which antibodies directed to sources of infection in body fluids can be assayed with high accuracy, expediency and specificity. More particularly, the invention provides an antibody immunoassay method in which the antigen-ant... | 05/06/2008 |
| 7361480 | Method and means for detecting gluten-induced diseases The invention is directed to a method of detecting gluten-induced diseases such as e.g. celiac disease and dermatitis herpetiformis. Said diseases are indicated by the presence of autoantibodies against tissue transglutaminase tTG in the blood The test is carried ou... | 04/22/2008 |
| 7358058 | Method and agents for the diagnosis and therapy of chronic inflammatory intestinal disease Methods for diagnosis, early diagnosis, differential diagnosis, assessment of the severity and therapy-accompanying monitoring and prognosis of chronically inflammatory intestinal diseases (Crohn's disease, Colitis ulcerosa), in which the presence and/or the ... | 04/15/2008 |
| 7358052 | Catalytic amplification of multiplexed assay signals Methods, compositions, kits, and a system are disclosed for detecting one or more analytes in a sample. A mixture comprising the (i) sample, (ii) a first binding reagent comprising a cleavage-inducing moiety and a first binding agent specific for an analyte, and (ii... | 04/15/2008 |
| 7344846 | Diagnostics and therapeutics for macular degeneration-related disorders The invention relates to methods for diagnosing and treating macular degeneration-related disorders. The invention also related to methods for identifying genes that cause macular degeneration-related disorders. ... | 03/18/2008 |
| 7344849 | Assay The present invention relates to assay methods for the determination of cobalamin or vitamin B12 in a body fluid and in particular to assay methods for the metabolically active pool of cobalamin, comprising contacting a cell free sample of a body fluid wi... | 03/18/2008 |
| 7344848 | Methods for determining adequacy of heat processing of a cooked meat sample Monoclonal antibodies are provided which bind to heat-treated proteins of meats. The antibodies are useful in detecting the presence of an exogenous meat in a cooked or raw meat sample. Furthermore, the antibodies can be used to determine the end point temperature o... | 03/18/2008 |
| 7335477 | Truncated recombinant major outer membrane protein antigen (r56) of strains Karp, Kato and Gilliam and its use in antibody based detection assays and vaccines A recombinant, refolded non-fusion polypeptide expressed from a truncated r56 gene of the causative agent of scrub typhus, Orientia tsutsugamushi for the Karp, Kato and Gilliam strains has been produced. The invention is useful for detecting prior exposure to... | 02/26/2008 |
| 7335724 | Peptides immunoreactive with autoantibodies from patients suffering from rheumatoid arthritis The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine res... | 02/26/2008 |
| 7297551 | Recombinant proteins and peptides for endotoxin biosensors, endotoxin removal, and anti-microbial and anti-endotoxin therapeutics Recombinant fragments of Factor C are disclosed. These proteins and peptides show great potency in recognizing, binding to, neutralizing and removing endotoxin. These molecules can thus be used for anti-microbial, anti-endotoxin, and anti-sepsis therapy. SSCrFCES is... | 11/20/2007 |
| 7285411 | High throughput screening assay systems in microscale fluidic devices The present invention provides novel microfluidic devices and methods that are useful for performing high-throughput screening assays. In particular, the devices and methods of the invention are useful in screening large numbers of different compounds for their effe... | 10/23/2007 |
| 7279295 | Allergen The present invention relates to a novel allergen from timothy grass (Phleum pretense) pollen, Phl p11 as disclosed in SEQ ID NO:2, and use thereof as a reagent and in a diagnositic kit as well as for immunotherapy. ... | 10/09/2007 |
| 7271251 | adhesin binding group antigen A novel Helicobacter pylori blood group antigen binding (BAB) adhesin protein was isolated and purified, whereby said protein or fractions thereof bind specifically to fucosylated blood group antigens. The protein sequence of said adhesin is disclosed in this... | 09/18/2007 |
| 7270964 | Detection of antibodies to squalene in serum The invention is a method for detecting squalene in sera. ... | 09/18/2007 |
| 7264939 | Method of detecting native proBNP The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a h... | 09/04/2007 |
| 7264938 | Method of detecting native proBNP The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a h... | 09/04/2007 |
| 7258994 | Saliva immunoassay for detection of antibodies for cardiovascular disease A method for diagnosing the likelihood and severity of cardiovascular disease in a patient is disclosed. The method determines the levels of antibodies against autoantigens, including myosin, oxidized LDL, β-2-glycoprotein, heat shock protein-60, platelet glycoprot... | 08/21/2007 |
| 7255999 | Methods and compositions for analyzing proteins Methods, compositions and kits are disclosed for determining one or more target polypeptides in a sample where the target polypeptides have undergone a post-translational modification. A mixture comprising the sample and a first reagent comprising a cleavage-inducin... | 08/14/2007 |
| 7252951 | Essential downstream component of the wingless signaling pathway and therapeutic and diagnostic applications based thereon The present invention relates to a new essential downstream component of the Wnt/Wingless (Wnt/Wg) signaling pathway and therapeutic and diagnostic applications based thereon. The invention relates to nucleotide sequences of the Drosophila melanogaster legles... | 08/07/2007 |
| 7252961 | Competitive immunoassay using complexed analyte derivatives The invention relates to a method for the detection of an analyte in a competitive immunoassay in the presence of an analyte derivative and first and second receptor molecules, and to a kit for carrying out this detection method. ... | 08/07/2007 |