User-operated amusement apparatus for kicking the user's buttocks
An apparatus including a user-operated and controlled apparatus for self-infliction of repetitive blows to the user's buttocks by a plurality of elongated arms bearing flexible extensions that rotate under the user's control.
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| Number | Title | Issue Date |
| 7399609 | /patents/7399609/description.html The invention relates to methods of detecting staphylococcus. ... | 07/15/2008 |
| 7364918 | Colorimetric sensors constructed of diacetylene materials Colorimetric sensors comprising a receptor incorporated within polydiacetylene assemblies to form a transducer capable of indicating a color change when contacted with an analyte are disclosed. Methods of using the colorimetric sensor and a kit for the colorimetric ... | 04/29/2008 |
| 7358076 | Sublancin lantibiotic produced by 168 An antimicrobial peptide produced by Bacillus subtilis 168 was isolated and characterized and named sublancin 168. The invention includes DNA encoding for the sublancin 168 peptides and peptides which are at least 80% identical to the sublancin 168 peptide. T... | 04/15/2008 |
| 7279162 | Isolated broadly reactive opsonic immunoglobulin for treating a pathogenic coagulase-negative staphylococcus infection The invention describes the identification, making, and isolation of immunoglobulin and antigen useful for preventing, diagnosing, and treating staphylococcal infections. The invention further describes an in vivo animal model useful for testing the efficacy of phar... | 10/09/2007 |
| 7270969 | Methods of constructing and screening diverse expression libraries The present invention provides novel methods for producing nucleic acid fragment libraries that express highly diverse peptides or protein domains and, in particular, methods for producing nucleic acid fragment libraries wherein the nucleic acid fragments of the lib... | 09/18/2007 |
| 7234414 | Mastitis detection Method and apparatus for testing a milk for mastitis wherein the milk sample is admixed with a detergent under condition that increase the viscosity of the milk sample; the increased viscosity mixture is subjected to a further procedure for further increasing its vi... | 06/26/2007 |
| 7223534 | Diffraction-based diagnostic devices A biosensor includes a substrate with a layer of receptive material disposed thereon. The receptive material is specific for an analyte of interest. A pattern of active and deactivated areas of the receptive material are defined in the receptive material layer by a ... | 05/29/2007 |
| 7045131 | Staphylococcal immunotherapeutics via donor selection and donor stimulation A method and composition for the passive immunization of patients infected with or susceptible to infection from Staphylococcus bacteria such as S. aureus and S. epidermidis infection is provided that includes the selection or preparation of a d... | 05/16/2006 |
| 7015007 | Capsular polysaccharide adhesin antigen, preparation, purification and use A substantially pure capsular exopolysaccharide adhesin of coagulase-negative staphylococcal strains, and a gonoral method to prepare such adhesins, are described. Vaccines composed of such adhesins, and uses of such adhesins to produce polyclonal and monoclonal ant... | 03/21/2006 |
| 7005510 | Recombinant DNase B derived from The gene for Streptococcus pyogenes DNase B has been cloned and vectors incorporating the cloned DNA have been used to transform Escherichia coli, allowing efficient and rapid production of the DNase in E. coli without the necessity of growing l... | 02/28/2006 |
| 6979446 | Monoclonal antibodies to the ClfA protein and method of use in treating or preventing infections Monoclonal antibodies which can bind to the ClfA protein and which are generated from binding subdomains or active fragments of the ClfA protein from Staphylococcus aureus, including the active fragments proteins from its fibrinogen binding domain such as Clf... | 12/27/2005 |
| 6936258 | Staphylococcus antigen and vaccine A negatively-charged Staphylococcus antigen contains amino acids and a N-acetylated hexosamine as a major carbohydrate component. The antigen is common to many coagulase-negative strains of Staphylococcus, including S. epidermidis, S. haemolyticus | 08/30/2005 |
| 6858439 | Compositions and methods for separation of moieties on chips The present invention recognizes that separation of components of a sample facilitate, and are often necessary for, sample analysis. Dielectrophoretic separation provides an efficient, reliable, nondisruptive, and automatable method for the separation of moieties in... | 02/22/2005 |
| 6858398 | Saliva test for detection of food allergy and intolerance A method for determining the presence of food allergy or food intolerance and their cross-reactive tissue antigens is disclosed. The method includes determining a level of antibodies against a dietary antigen in a mucosal sample from the patient and comparing the le... | 02/22/2005 |
| 6815172 | Methods and compositions for opsonophagocytic assays Methods and compositions comprising immunoassays for the detection of functional antibodies and the analysis of vaccine efficacy are described. In particular, the present invention provides opsonophagocytic assays. The assays are useful for the rapid and simultaneou... | 11/09/2004 |
| 6790448 | Surface proteins from gram-positive bacteria having highly conserved motifs and antibodies that recognize them Isolated peptide sequences and proteins containing these sequences are provided which are useful in the prevention and treatment of infection caused by Gram-positive bacteria. The peptide sequences have been shown to be highly conserved motifs in the surface protein... | 09/14/2004 |
| 6783930 | Development of novel anti-microbial agents based on bacteriophage genomics A method for identifying suitable targets for antibacterial agents based on identifying targets of bacteriophage-encoded proteins is described. Also described are compositions useful in the identification methods and in inhibiting bacterial growth, and methods for p... | 08/31/2004 |
| 6767536 | Recombinant Staphylococcus thioredoxin reductase and inhibitors thereof useful as antimicrobial agents Isolated and purified Staphylococcus thioredoxin reductases (TrxB) are provided. Polynucleotides encoding the TrxBs, vectors and host cells containing such polynucleotides are also provided. In addition, antibodies reactive with the TrxBs are provided, as are method... | 07/27/2004 |
| 6747129 | Target of RNAIII activating protein(TRAP) The present invention is directed to a protein isolated from S. aureus that is the target of RAP, called TRAP, which is characterized by a molecular weight of about 21 KDa, is capable of being phosphorylated by RAP, and comprises an amino acid sequence of SEQ... | 06/08/2004 |
| 6740485 | Anti-bacterial methods and materials Staphylococcus aureus virulence genes are identified, thereby allowing the identification of novel anti-bacterial agents that target these virulence genes and their products, and provision of novel S. aureus mutants useful in vaccines. ... | 05/25/2004 |
| 6720160 | Method for simultaneous detection of multiple microbial antigens in biological specimens from mastitic animals The present invention involves a method and an immuno-analytical device for the rapid and simultaneous detection of multiple micro-organisms in the biological fluids from milk-producing animals suffering from mastitis. This method is based on a lateral flow immuno-a... | 04/13/2004 |
| 6713250 | Identification of human allergens and T-lymphocyte antigens in vitro The invention provides a method for screening a test compound for the ability of the test compound to induce a response from human naive T-cells. The method comprises admixing human naive T cells, macrophages/monocytes, immortalized B cells lacking class I and class... | 03/30/2004 |
| 6689569 | Saliva test for detection of food allergy, candidiasis, microflora imbalance, intestinal barrier dysfunction and humoral immunodeficiencies A method for determining a cause for digestive and immune disorders is disclosed. The method determines the levels of antibodies against normal intestinal microflora and food antigens. It then compares the results to normal levels to determine the cause. ... | 02/10/2004 |
| 6686169 | Reagent for the detection of Staphylococcus aureus by agglutination Reagents and methods for the detection of Staphylococcus aureus are provided. The reagents contain an antibody that binds to a capsular polysaccharide of type 5 of Staphylococcus aureus, and can be used in methods for detection of oxacillin resistant Stap... | 02/03/2004 |
| 6630355 | Magnetic focusing immunosensor for the detection of pathogens A magnetic focusing immunosensor for the detection of pathogens comprising a laser, an exciting fiber and a collecting fiber, a fiber optic magnetic probe in communication with the collecting and exciting fibers and means for detecting, collecting and mea... | 10/07/2003 |
| 6566508 | Fluorogenic compounds and uses therefor Disclosed are novel coumarin based fluorogenic compounds useful in assaying for biological activity. Specifically, these fluorogenic compounds exhibit fluorescence at particular wavelengths when cleaved by target enzymes. Preferred compounds include sugar... | 05/20/2003 |
| 6528272 | Receptor-based assays for pathogens A rapid, simple, and inexpensive sandwich enzyme-linked receptor based immunodot assay detects pathogens or pathogenic products in test samples using receptors for a characteristic component of the pathogen. This assay is widely applicable because it is h... | 03/04/2003 |
| 6485899 | Anti-bacterial methods and materials Staphylococcus aureus virulence genes are identified, thereby allowing the identification of novel anti-bacterial agents that target these virulence genes and their products, and the provision of novel S. aureus mutants useful in vaccines.... | 11/26/2002 |
| 6482602 | Reagent for the detection of Staphylococcus aureus by agglutination Reagents and methods for the detection of Staphylococcus aureus are provided. The reagents contain an antibody that binds to a capsular polysaccharide of type 5 of Staphylococcus aureus, and can be used in methods for detection of oxacillin resistant Stap... | 11/19/2002 |
| 6475788 | Anti-bacterial antibodies and methods of use A process of preparing a pharmaceutical composition includes the steps of: a) obtaining isolated immunoglobulins from an animal; b) contacting the isolated immunoglobulins with a bacterial Fc-binding protein; c) collecting the immunoglobulins not bound to... | 11/05/2002 |
| 6410696 | Cyclosporin immunoassay A method of measuring the amount of cyclosporin in a sample suspected of containing cyclosporin is disclosed. A method of inactivating interfering cross-reactive material in an assay for measuring the amount of cyclosporin in a sample suspected of contain... | 06/25/2002 |
| 6340571 | Antibodies specific for Staphylococcus aureus, and use thereof A monoclonal or polyclonal antibody specific for an epitope common to Staphylococcus aureus strains of various capsular serotypes, particularly methicillin-resistant strains, the antibody being selected from immunoglobulins G, M, and A, and the use thereo... | 01/22/2002 |
| 6316211 | ThdF The invention provides thdF polynucleotides encoding thdF polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing thdF polypeptides to screen for antibacterial compounds.... | 11/13/2001 |
| 6228602 | Competitive apo-peroxidase assay Disclosed is an assay for an analyte in a fluid test sample such as urine which involves combining the fluid test sample with a reagent system comprising an apo-peroxidase, a redox dye, a peroxide and a metal porphyrin which is bound to an analyte/analyte... | 05/08/2001 |
| 6165740 | Method and device for flow-cytometric microorganism analysis To reduce the effects of the contaminants in the measurement of microorganisms and the reduction of the time necessary for the measurement. Measurement is performed of the microorganism prior to and following culture, and the difference between the two is... | 12/26/2000 |
| 6156524 | Reagent for the detection of Staphylococcus aureus by agglutination Reagents and methods for the detection of Staphylococcus aureus are provided. The reagents contain an antibody that binds to a capsular polysaccharide of type 5 of Staphylococcus aureus, and can be used in methods for detection of oxacillin resistant Stap... | 12/05/2000 |
| 6143868 | Monofunctional glycosyltransferase of Staphylococcus aureus The invention provides isolated nucleic acid compounds encoding a novel MTG of Staphylococcus aureus. Also provided are vectors and transformed heterologous host cells for expressing the MTG and a method for identifying compounds that bind and/or inhibit ... | 11/07/2000 |
| 5998128 | Use of porphyrins in instrumental detection methods The present invention relates to a process for quantifying entities, comprising the steps of (a) mixing an effective detection amount of a (proto-) porphyrin represented by formula (I) ##STR1## wherein R1 independently represents a radical... | 12/07/1999 |
| 5955074 | Directed human immune globulin for the prevention and treatment of staphylococcal infections This invention is directed to a Directed Human Immoglobulin and compositions thereof for preventing or treating staphylococcal infections such as S. epidermidis in neonates.... | 09/21/1999 |
| 5922549 | Process for screening substances having a modulating effect on an interleukin-5 receptor mediated cellular signal transmission pathway A process is disclosed for screening substances having a modulating effect on the interleukine-5-receptor-dependent signal tranmission path in mammal cells. Test substances are applied on cells which express the functional interleukine-5-receptor and are ... | 07/13/1999 |