User-operated amusement apparatus for kicking the user's buttocks
An apparatus including a user-operated and controlled apparatus for self-infliction of repetitive blows to the user's buttocks by a plurality of elongated arms bearing flexible extensions that rotate under the user's control.
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| Number | Title | Issue Date |
| 8105795 | Methods, devices, kits and compositions for detecting roundworm Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm in a f... | 01/31/2012 |
| 8043825 | Serum biomarkers for Chagas disease The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying Chagas disease status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as infected with Chagas disea... | 10/25/2011 |
| 8012706 | Methods for detecting virulent , for evaluating virulence, and for screening new drugs employing the 3′UTR of SUB2 and the SUB2 serine protease Methods for regulating the serine protease of Plasmodium. Recombinant DNA constructs which express the Plasmodium serine protease, especially those comprising a sub2 3′UTR and coding segment which express a SUB2 a serine protease. Recombinant Plas... | 09/06/2011 |
| 7993861 | Methods, devices, kits and compositions for detecting whipworm Methods, devices, kits and compositions for detecting the presence or absence of whipworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of whipworm in a fec... | 08/09/2011 |
| 7993862 | Methods, devices, kits and compositions for detecting roundworm Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a mammalian sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm in... | 08/09/2011 |
| 7993860 | Polypeptides recognized by anti-antibodies, and uses thereof The present invention relates to new polypeptides recognized by anti-Trichinella antibodies. The invention also relates to the use of said polypeptides for the detection of anti-Trichinella antibodies and for the prevention of trichinellosis. ... | 08/09/2011 |
| 7964366 | Methods and compositions for detection of (VLPT) The invention provides methods and compositions for the detection of Ehrlichia chaffeensis. ... | 06/21/2011 |
| 7727734 | Detection and measurement of blood-feeding activity This invention provides compositions and methods for detection of hematophagous ectoparasitic activity in an enclosure or area. The compositions comprise a reagent or reagents which are reactive against antigens or markers as they appear in the excrement or other ec... | 06/01/2010 |
| 7695925 | Compositions and methods for the detection of infection Compositions comprising fusion polypeptides of T. cruzi epitopes are provided, together with methods for the use of such compositions in the diagnosis of T. cruzi infection and in screening blood supplies. Diagnostic kits comprising such compositions a... | 04/13/2010 |
| 7666612 | Methods for protein labeling based on acyl carrier protein A method for labeling acyl carrier protein (ACP) fusion proteins with a wide variety of different labels is disclosed. The method relies on the transfer of a label from a coenzyme A type substrate to an ACP fusion protein using a holo-acyl carrier protein synthase (... | 02/23/2010 |
| 7611853 | Assay to screen for anti-malarials Malarial parasite Plasmodium falciparum is responsible for the most severe form of malaria in humans, causing about 2 million deaths every year. Lack of effective vaccines and emergence of drug-resistant strains necessitate the need of novel drug targets to t... | 11/03/2009 |
| 7514230 | Detection of trichomonas The present invention is directed to diagnostic devices and methods for detecting Trichomonas infections. ... | 04/07/2009 |
| 7432046 | Methods for the determination of antibody IgG avidity The present invention relates to methods of determining anti-infectious agent IgG avidity, for example, human anti-cytomegalovirus and human anti-toxoplasma IgG avidity, using a competitive assay format. ... | 10/07/2008 |
| 7393647 | Methods for detecting infection This invention pertains to methods for detecting B. anthracis and antibodies to B. anthracis, the causative agent of anthrax, in a subject. ... | 07/01/2008 |
| 7374888 | Methods for detecting infection This invention pertains to methods for detecting B. anthracis and antibodies to B. anthracis, the causative agent of anthrax, in a subject. ... | 05/20/2008 |
| 7368132 | Glyoxal/zinc fixative This invention provides compositions and methods for fixing a biological sample, particularly fecal samples for diagnosis of parasitic infection. The fixative composition of the present invention comprises glyoxal (pyruvate aldehyde) and zinc sulfate and permits sta... | 05/06/2008 |
| 7341870 | Dendritic cell line The invention relates to plasmacytoid dendritic human cell lines and methods for producing the cell lines. More specifically, the invention relates to the plasmacytoid dendritic human cell line called GEN2.2, which is deposited in the CNCM under number CNCM 1-2938 a... | 03/11/2008 |
| 7335505 | Materials and methods relating to protein aggregation in neurodegenerative disease The present invention provides methods of proteolytically converting a precursor protein (e.g. tau) to a product fragment (e.g., a 12 kd fragment) in a stable cell line, wherein the precursor protein is associated with a disease state in which the precursor protein ... | 02/26/2008 |
| 7335477 | Truncated recombinant major outer membrane protein antigen (r56) of strains Karp, Kato and Gilliam and its use in antibody based detection assays and vaccines A recombinant, refolded non-fusion polypeptide expressed from a truncated r56 gene of the causative agent of scrub typhus, Orientia tsutsugamushi for the Karp, Kato and Gilliam strains has been produced. The invention is useful for detecting prior exposure to... | 02/26/2008 |
| 7294477 | Allergen and treatment The present invention is related to novel nucleoli sequences encoding a louse allergen and a methods for diagnosing, treating and preventing lice infestation and associated allergic disease with the nucleoli sequences and protein allergen of the invention. The prese... | 11/13/2007 |
| 7291477 | Method and device for detection A method and kit for detecting Trichomonas vaginalis infection in a human subject are disclosed. In the method, a body-fluid sample such as a vaginal swab sample or urine is obtained from the subject and contacted with an antibody specific against a Tricho... | 11/06/2007 |
| 7277176 | Emission filter X-Y array An imaging system for obtaining images of a specimen that includes a novel filtering system for filtering radiation emitted from the specimen. The imaging system includes a camera and a novel filter grid that is controllably movable relative to the camera in a manne... | 10/02/2007 |
| 7250173 | Use of parasitic biological agents for prevention and control of autoimmune diseases The invention relates to a method of treating an excessive immune response including an aberrant/enhanced Th1 response by administering a helminthic parasite preparation in an amount sufficient to reduce the excessive immune response in an individual. This invention... | 07/31/2007 |
| 7223534 | Diffraction-based diagnostic devices A biosensor includes a substrate with a layer of receptive material disposed thereon. The receptive material is specific for an analyte of interest. A pattern of active and deactivated areas of the receptive material are defined in the receptive material layer by a ... | 05/29/2007 |
| 7214531 | Pressure transduced chemical assay and method An assay system has a chamber that receives a test strip onto which a sample comprising an analyte has been placed. The chamber is in gaseous communication with a piezoelectric material that generates an electrical signal in response to a pressure change in the cham... | 05/08/2007 |
| 7176286 | Antigen fragments for the diagnosis of The invention described herein relates to a method for identifying antigen fragments of Toxoplasma gondii proteins, and their use as diagnostic and immunogenic agents. Said method is implemented by means of selection of DNA fragments libraries of the parasite... | 02/13/2007 |
| 7169550 | Diffraction-based diagnostic devices A biosensor includes a substrate with a receptive material layer of radiation-absorbing member (RAM)-tagged biomolecules disposed thereon. The receptive material is specific for an analyte of interest. A pattern of active and deactivated areas of the receptive mater... | 01/30/2007 |
| 7166290 | Methods for producing oocysts The present invention provides improved methods and compositions for producing oocysts. The oocysts produced according to the invention find use in the manufacture of vaccines. In preferred embodiments, the present invention provides methods and compositions for the... | 01/23/2007 |
| 7163799 | Neuromedin U receptor NMUR2 and nucleotides encoding it A new neuromedin U receptor, designated NMUR2 has been found, which is involved in modulation of feeding behavior in mammals. Ligands of this receptor are able to modulate eating, and weight gain. Amino acid sequences of the human and rat forms, as well as their nuc... | 01/16/2007 |
| 7153819 | Stabilization of antibodies or fragments thereof There is provided an antibody granule, consisting essentially of one or more antibodies, or fragments derived thereof, granulated with an alkali metal salt. Also provided is a process for preparing said antibody granules. The granules can be used in an enzymatic sta... | 12/26/2006 |
| 7129056 | Method for the detection, identification, enumeration and confirmation of virally infected cells and other epitopically defined cells in whole blood A method for analyzing blood enables one to isolate, detect, enumerate and confirm under magnification the presence of target cells which have expressed surface epitopes that indicate intracellular infection by various viruses or other infectious agents, and also ce... | 10/31/2006 |
| 7109038 | Occult blood detection in biological samples by laser desorption and matrix-assisted laser desorption/ionization mass spectrometry for biomedical applications Methods are described for detecting and quantifying occult blood in a biological sample using laser desorption mass spectrometry (LD MS). Biological samples that can be analyzed using various embodiments of the present invention include stool (fecal occult blood, FO... | 09/19/2006 |
| 7094879 | Genetically engineered P30 antigen, improved antigen cocktail, and uses thereof The present invention relates to a genetically engineered P30 antigen and a combination or mixture of antigens (e.g., the genetically engineered P30 antigen and P35) that may be used in the detection of IgM and/or IgG antibodies to Toxoplasma gondii. Furtherm... | 08/22/2006 |
| 7094576 | Methods and compositions for detecting larval with a cloned diagnostic antigen Compositions and methods for the detection of Taenia solium and the diagnosis of T. solium infection are described. The nucleotide and amino acid sequences of the antigenic T. solium polypeptides gp50a, gp50b and gp50c are provided. The composit... | 08/22/2006 |
| 7087231 | Peptide sequences specific for the hepatic stages of bearing epitopes capable of stimulating the T lymphocytes The present invention relates to an in vitro diagnostic method for malaria in an individual comprising placing a tissue or a biological fluid taken from an individual in contact with a molecule or polypeptide composition, wherein said molecule or polypeptide composi... | 08/08/2006 |
| 7071296 | antigens inducing protective antibodies The present invention relates to immunogenic compositions comprising as an immunogen a long synthetic or recombinant peptide of a merozoite surface protein 3b (MSP-3b) peptide, an MSP-3c peptide and a MSP-3d peptide. Vaccines against malaria are also disclosed using... | 07/04/2006 |
| 7067315 | Identification of anti-protozoal agents The present invention provides novel assay systems and methods for monitoring cell invasion by protozoal parasites. The present invention further provides methods of using these assays systems to identify compounds that treat or prevent protozoal infection. The pres... | 06/27/2006 |
| 7056518 | Malarial pre-erythrocytic stage polypeptide molecules Polypeptide molecules containing at least 10 consecutive amino acids of the amino acid sequence shown in FIG. 2, representing the LSA3 antigen, the following peptides being excluded: | 06/06/2006 |
| 7052858 | Diagnostic assays for detection of This invention provides a novel Cryptosporidium parvum protein disulfide isomerase polypeptide, and nucleic acids that encode this polypeptide. The invention also provides methods, reagents, and kits that are useful for diagnosing infection by Cryptosporid... | 05/30/2006 |
| 7041293 | HIV env antibodies The invention provides antibodies specific for HIV env, including monoclonal antibodies and related hybridomas. The antibodies block CD4/g120 binding and reduce reverse transcriptase activity in vitro. ... | 05/09/2006 |