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Combination Beverage Container and Spittoon
A combination beverage container and spittoon includes a bottom portion including outer wall and a first inner wall defining a spittoon space.
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| Number | Title | Issue Date |
| 8173396 | Methods for reducing gluconoylation of proteins The present invention relates to methods of preventing glyconoylation of polypeptides produced in micororganisms. ... | 05/08/2012 |
| 8133700 | Latent phase viral interleukin-10-(VII-10) and uses thereof The present invention relates to a purified nucleic acid sequence encoding a homologue of human interleukin 10 (IL-10), wherein said IL-10 homologue is expressed during the latent phase of infection by a virus of the herpesvirideae group. The present invention also ... | 03/13/2012 |
| 8088600 | Nucleic acids encoding cynomolgus IL-13 mutein proteins The present invention relates to at least one novel cynomolgus IL-13 muteins (Mut-IL-13) proteins, antibodies, including isolated nucleic acids that encode at least one Mut-IL-13 protein or antibody, Mut-IL-13 vectors, host cells, transgenic animals or plants, and m... | 01/03/2012 |
| 8084232 | Polynucleotides encoding toll-like receptor 3 Isolated polynucleotides encoding Papio cynocephalus Toll-Like Receptor 3 (Baboon TLR3), polypeptides obtainable from expression of these polynucleotides, recombinant cells, and methods of use are disclosed. ... | 12/27/2011 |
| 8080392 | IL-D80 polynucleotides Purified genes encoding a cytokine or composite cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding these molecules are provided. Methods of using said reagents and diagnostic kits are also pr... | 12/20/2011 |
| 8062864 | Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies The present invention is directed to antibodies and fragments thereof and humanized versions thereof having binding specificity for IL-6. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the s... | 11/22/2011 |
| 7968315 | Production and purification of IL-29 The expression vectors and methods using an E. coli expression system for the large scale production of IL-29 are described. The vectors utilize the IL-29 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary stru... | 06/28/2011 |
| 7947474 | Nucleic acid encoding cytokine receptor ZCYTOR17 Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zyctor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or devel... | 05/24/2011 |
| 7939297 | Mammalian cytokines; related reagents and methods Nucleic acids encoding mammalian, e.g., primate, IL-1ζ, purified IL-1ζ polypeptides and fragments thereof. Binding proteins, e.g., antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic ... | 05/10/2011 |
| 7910331 | Nucleic acids encoding murine IL-174 CTLA-8 related antigens from mammals, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigens. Methods of using said reagents and diagnostic kits are also provided. ... | 03/22/2011 |
| 7888071 | DNA encoding IL-2 fusion proteins with modulated selectivity The invention provides cytokine fusion proteins with an increased therapeutic index, and methods to increase the therapeutic index of such fusion proteins. The fusion proteins of the invention are able to bind to more than one type of cytokine receptor expressed on ... | 02/15/2011 |
| 7833754 | IL-12 for expression in mammalian cell The present invention provides for nucleic acids improved for the expression of interleukin-12 (IL-12) in mammalian cells. The invention further provides for methods of expressing IL-12 in mammalian cells by transfecting the cell with a nucleic acid sequence encodin... | 11/16/2010 |
| 7759092 | Production and purification of IL-29 The expression vectors and methods using an E. coli expression system for the large scale production of IL-29 are described. The vectors utilize the IL-29 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary stru... | 07/20/2010 |
| 7745176 | IL-21 production in prokaryotic hosts The expression vectors and methods using an E. coli expression system for the large scale production of IL-21 are described. The vectors utilize the IL-21 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary stru... | 06/29/2010 |
| 7704710 | Interleukin-9 receptor mutants This invention relates to the diagnosis, treatment and methods for discovery of new therapeutics for atopic asthma and related disorders based on variants of Asthma Associated Factor 2. One embodiment of the invention is a variant of AAF2 wherein codon 173 is delete... | 04/27/2010 |
| 7662589 | Polynucleotide encoding an IL-28A polypeptide Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor... | 02/16/2010 |
| RE41129 | Cytokine zalpha11 ligand polynucleotides The present invention relates to zalpha11 Ligand polynucleotide and polypeptide molecules. The zalpha11 Ligand is a novel cytokine. The polypeptides may be used within methods for stimulating the proliferation and/or development of hematopoietic cells in vitro and i... | 02/16/2010 |
| 7662590 | Polynucleotide encoding an IL-28A polypeptide Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor... | 02/16/2010 |
| 7638305 | Polynucleotide encoding an IL-28A polypeptide Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor... | 12/29/2009 |
| 7629149 | Polynucleotide encoding an IL-28A polypepide Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor... | 12/08/2009 |
| 7629148 | Polynucleotide encoding an IL-28B polypeptide Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor... | 12/08/2009 |
| 7625720 | Nucleic acids encoding IL-174 CTLA-8 related antigens from mammals, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigens. Methods of using said reagents and diagnostic kits are also provided. ... | 12/01/2009 |
| 7608428 | Polynucleotide encoding an IL-28B polypeptide Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor... | 10/27/2009 |
| 7608427 | Polynucleotide encoding an IL-28B polypeptide Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor... | 10/27/2009 |
| 7598058 | Nucleic acids encoding IL13 mutants This invention provides nucleic acid molecules encoding mutant human interleukin 13 molecules showing varying specificity for the restricted (IL4 independent) IL13 receptor. The mutant hIL13 molecules include those made by substituting the amino acid residues that o... | 10/06/2009 |
| 7595174 | Polynucleotide encoding an il-29 polypeptide Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor... | 09/29/2009 |
| 7588918 | Polynucleotide encoding an IL-29 polypeptide Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor... | 09/15/2009 |
| 7588919 | Polynucleotide encoding an IL-28B polypeptide Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor... | 09/15/2009 |
| 7582450 | Polynucleotide encoding an IL-29 polypeptide Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor... | 09/01/2009 |
| 7534585 | Multifunctional cytokines The present invention relates to a novel fusion protein with the formula X—Y, or Y—X, wherein X represents a first immunoregulating polypeptide and Y represents a second immunoregulating polypeptide different from X. The present invention also relates to a nucle... | 05/19/2009 |
| 7442526 | Method for preparing a physiologically active IL-18 polypeptide The present invention provides a method for producing physiologically active human Interleukin-18 (“IL-18”). ... | 10/28/2008 |
| 7427494 | Nucleic acid encoding cytokine receptor zcytor17 Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or devel... | 09/23/2008 |
| 7423123 | Interleukin-9 antagonist muteins and their pharmacological methods of use This invention relates to IL-9 muteins that inhibit the activity of wild-type IL-9, multimers and Fc-fusion constructs of IL-9 proteins, and an efficient method to purify IL-9 proteins produced by eukaryotic cells. Related formulations, dosages and methods of admini... | 09/09/2008 |
| 7417134 | IL-1 receptor based cytokine traps and method of using The present invention provides a fusion polypeptide capable of binding interleukin-1 (O:-1) to form a nonfunctional complex. It also provides a nucleic acid sequence encoding the fusion polypeptide and methods of using the fusion polypeptide. ... | 08/26/2008 |
| 7374911 | Interleukin-1 related gene and protein Disclosed in an interleukin-1 related gene and gene product. In particular, the invention relates to a protein that is highly homologous to known interleukin-1 cytokines, nucleic acid molecules that encode such a protein, antibodies that recognize the protein, and m... | 05/20/2008 |
| 7374912 | Nucleic acids encoding chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof Chimeric proteins constructed from the fusion of the naturally occurring form of the soluble IL-6 receptor and IL-6 which are useful for treatment of cancer and liver disorders, enhancement of bone marrow transplantation, and treatment of other IL-6 related conditio... | 05/20/2008 |
| 7364724 | Recombinant super-compound interferon This invention provides a recombinant super-compound interferon or an equivalent thereof with changed spatial configuration. The super-compound interferon possesses anti-viral or anti-tumor activity and therefore is useful to prevent and treat viral diseases and can... | 04/29/2008 |
| 7351555 | Mouse cytokine receptor Zcytor16 Cytokines and their receptors have proven usefulness in both basic research, animal models, and as therapeutics. The present invention provides a new cytokine receptor designated as “mouse Zcytor16,” which can bind and antagonize the IL-TIF cytokine. ... | 04/01/2008 |
| 7347995 | Compositions and methods for achieving immune suppression Disclosed herein are therapeutic compositions containing agents that modulate the immune response in a patient. ... | 03/25/2008 |
| 7341851 | IL-8 like protein This present invention relates to a novel protein, termed INSP085, herein identified as an IL-8 like protein and to the use of this protein and nucleic acid sequence from the encoding genes in the diagnosis, prevention and treatment of disease. ... | 03/11/2008 |
