Class 435/56 - Hydroxylating at 17-position

Subclass of Class 435 - Chemistry: molecular biology and microbiology
Definition: Processes wherein the product synthesized has a hydroxyl
No. of patents: 22
Last issue date: 10/07/2008

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Number	Title	Issue Date
7432075	Indentification of 3-ketosteroid 9-alfa-hydroxylase genes and microorganisms blocked in 3-ketosteroid 9-alfa-hydroxylase activity The invention relates to an isolated polynucleotide sequence comprising a nucleic acid sequence encoding the amino acid sequence of KshA protein or of KshB protein, encoded by nucleotides 499-1695 of SEQ ID NO:1 or by nucleotides 387-1427 of SEQ ID NO:2, respectivel...	10/07/2008
7364429	Methods and apparatus for determining horizontal and vertical plane orientation for construction of dental prostheses Methods and systems for establishing dental bite planes in relation to the relative vertical and horizontal planes of a patient's face and head. A U-shaped bite fork, which can be held by the patient's teeth or gums, may be attached to a connection system that attac...	04/29/2008
7361821	Controlled alignment of nanobarcodes encoding specific information for scanning probe microscopy (SPM) reading The methods, apparatus and compositions disclosed herein concern the detection, identification and/or sequencing of biomolecules, such as nucleic acids or proteins. In certain embodiments of the invention, coded probes comprising a probe molecule attached to one or ...	04/22/2008
7128574	Dental alignment instrument A handheld dental instrument has a horizontal level indicator and a vertical midline angle marker pin mounted on a bite line plate. The bite line plate has an arcuate front and a pair of protruding positioning pins. The bite line plate is rotatably mounted to a hand...	10/31/2006
7041475	Purified and isolated platelet calcium channel nucleic acids Isolated and purified platelet voltage dependent calcium channel (VDCC) α1 subunit polypeptides, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed, along with metho...	05/09/2006
7033779	Method for preparing steroids modified by yeast fermentation The invention concerns a novel method for producing hydroxylated and/or acetylated steroid comprising steps which consist in: culturing yeasts on a medium comprising at least a precursor of such hydroxylated and/or acetylated steroids; then isolating the hydroxylate...	04/25/2006
6828120	Process to prepare 11β, 17α,21-trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate The present invention is a novel process for the transformation of 17α-hydroxy-6α-methylpregn-4-ene-3,20-dione 17-acetate (I) to 11β,17α,21-trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate (VI)	12/07/2004
6632633	Process for oxidation of steroids and genetically engineered cells used therein An expression cassette, operable in a recombinant host, comprising a heterologous DNA coding sequence encoding a protein, which is functional, alone or in cooperation with one or more additional proteins of catalyzing an oxidation step in the biological p...	10/14/2003
6582931	Dento-facial analyzer A face bow assembly including a face bow having a bite fork portion to carry an index trays to be positioned in a patient's mouth. The bow has outwardly extending wings to enable a dentist to support the bow. A vertical indicator rod mounted to the bow he...	06/24/2003
6162603	Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system The present invention contemplates chromophore-containing polynucleotides having at least two donor chromophores operatively linked to the polynucleotide by linker arms, such that the chromophores are positioned by linkage along the length of the polynucl...	12/19/2000
5849489	Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system The present invention contemplates chromophore-containing polynucleotides having at least two donor chromophores operatively linked to the polynucleotide by linker arms, such that the chromophores are positioned by linkage along the length of the polynucl...	12/15/1998
5429934	Process for the production of 20-methyl-5,7-pregnadiene-3ଲ,21-diol derivatives using mycobacterium 20 -Methyl-5,7-pregnadiene-3ଲ,21-diol derivatives of general formula I ##STR1## in which R1 means a hydrogen atom or a lower alkyl group and R2 means a lower alkyl group or R1 and R2 together represent a tetram...	07/04/1995
5298398	Preparation of 9-଱-hydroxy-17-keto steroids using Mycobacterium species CBS 482.86 9଱-hydroxy-17-keto steroids are prepared by fermenting steroids having a C-17-side chain of 5-10 carbon atoms inclusive, with the novel Mycobacterium species CBS 482.86. Starting from various substrates containing a 5-10 C carbon chain on C-17, ...	03/29/1994
5164302	Method for preparing 7ଲ-hydroxy-4-pregnene-3,20-dione derivatives Novel 7ଲ-hydroxy-4-pregnene-3,20-dione derivatives are disclosed. The group of these compounds has possibility of being utilized as an intermediate for the synthesis of progesterone derivatives having ovulation-inhibiting activity. These compounds themse...	11/17/1992
5004695	Microbiological process for preparing 9଱-hydroxy-4-androstene-3,17-dione The invention relates to a process for the production of 9଱-hydroxy-4-androstene-3,17-dione from natural sterols of plant or animal origin or from mixtures thereof by the submerged aerobic fermentation of an enzyme-deficient, sterol-de-grading micro...	04/02/1991
4950597	Modification of cellulose normally synthesizied by cellulose-producing microorganisms The present invention involves a process for screening for and isolating spontaneously occurring or induced cellulose II-producing microorganisms. The process comprises a series of steps in various embodiments. Initially, cellulose-producing microorganism...	08/21/1990
4546078	Polymer containing biocatalyst A biocatalyst contains microorganisms, e.g., of the species Arthrobacter simplex, Aspergillus ochraceus, Bacillus sphaericus, Curvularia lunata, Flavobacterium dehydrogenans, Mycobacterium spec., or Saccharaomyces uvarum, immobilized on a copolymer of acr...	10/08/1985
4528271	Process for the intensification of microbiological conversions of steroids using cyclodextrin additives Microbiological conversions of cyclodextrins are intensified by adding to the reaction mixture 0.2 to 3 moles of ଱-, ଲ- or γ-cyclodextrin or an optical mixture thereof pro mole of the steroid substrate, before, at the beginning or during the ...	07/09/1985
4320195	Steroid production A process for the production of useful steroids obtained by side chain degradation of sterol source materials through the use of microorganisms is described....	03/16/1982
4221868	Process for preparing 9଱-OH testosterone Valuable steroid intermediates, 9଱-hydroxyandrost-4-ene-17ଲ-ol-3-one (9଱-OH testosterone), 9଱-hydroxy-3-ketobisnorchol-4-en-22-ol (9଱-OH BN alcohol) and 9଱-hydroxy-3-ketobisnorchol-4-en-22-oic methyl ester (9³...	09/09/1980
4101378	Process for the microbiological oxidation of steroids The improvement in a process for the production of 17-hydroxyandrosta-1,4-dien-3-one and androsta-1,4-diene-3,17-dione by the microbiological oxidation of a sterol, its 4-en-3-one derivative or its 1,4-dien-3-one derivative, which comprises adding to the ...	07/18/1978
4057469	Process for the microbiological oxidation of steroids The improvement in a process for the production of 17-hydroxyandrosta-1,4-dien-3-one and androsta-1,4-diene-3,17-dione by the microbiological oxidation of a sterol, its 4-en-3-one derivative or its 1,4-dien-3-one derivative, which comprises adding to the ...	11/08/1977

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Class 435/56 - Hydroxylating at 17-position