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| Number | Title | Issue Date |
| 8008040 | Process for production of 5-ene-3-one or 3,6-dione derivatives of sterols, processes for production of lipid metabolism improvers, foods, drinks, and animal feeds, and analytical method An object of the present invention is to provide a process according to which 5-ene-3-one or 3,6-dione derivatives of sterols can be synthesized with a better yield, as well as a process for production of lipid metabolism improvers, foods, drinks, and animal feeds c... | 08/30/2011 |
| 7977065 | Yeast strains autonomously producing steroids The present invention relates to genetically modified yeast strains autonomously producing, from a simple carbon source, steroids. The invention also relates to a method for producing steroids from such yeast strains. ... | 07/12/2011 |
| 7901904 | Method and intermediates for preparing 2-alkoxy and 2-aryloxy estrogen compounds The present invention relates to a method for preparing 2-alkoxy and 2-aryloxyestrogen compounds, and the intermediate compounds prepared during the use of this method, which intermediate compounds are useful intermediates in the preparation of certain physiological... | 03/08/2011 |
| 7838264 | Method for producing antcin K, zhankuic acid A, zhankuic acid B or zhankuic acid C from the mycelium of The present invention provides a method for producing antcin K, zhankuic acid A, zhankuic acid B or zhankuic acid C from the mycelium of the fungus Antrodia cinnamomea by culturing the fungus on a gel medium, harvesting the mycelium and isolating the products... | 11/23/2010 |
| 7608421 | Method for the production of 7-dehydrocholesterol and/or the biosynthetic intermediate or subsequent products thereof in transgenic organisms The present invention relates to a method for preparing 7-dehydrocholesterol and/or the biosynthetic intermediates and/or secondary products thereof by culturing organisms, in particular yeasts. Furthermore, the invention relates to the preparation of the nucleic ac... | 10/27/2009 |
| 7556937 | Method for producing ergosta-5,7-dienol and/or biosynthetic intermediate and/or secondary products thereof in transgenic organisms The present invention relates to a method for the production of ergosta-5,7-dienol and/or its biosynthetic intermediates and/or metabolites by culturing genetically modified organisms, and to the genetically modified organisms, in particular yeasts, themselves. ... | 07/07/2009 |
| 7432075 | Indentification of 3-ketosteroid 9-alfa-hydroxylase genes and microorganisms blocked in 3-ketosteroid 9-alfa-hydroxylase activity The invention relates to an isolated polynucleotide sequence comprising a nucleic acid sequence encoding the amino acid sequence of KshA protein or of KshB protein, encoded by nucleotides 499-1695 of SEQ ID NO:1 or by nucleotides 387-1427 of SEQ ID NO:2, respectivel... | 10/07/2008 |
| 7300771 | Process to produce 19-nor-10β-carboxylic acids by fungal oxidation of 6-substituted-Δ6-pregnanes A process to produce 19-nor-10β-carboxylic acids by fungal oxidation of 6-substituted-Δ6-pregnanes is disclosed. ... | 11/27/2007 |
| 7291565 | Method and system for treating a substrate with a high pressure fluid using fluorosilicic acid A method and system is described for treating a substrate with a high pressure fluid, such as carbon dioxide in a supercritical state. A process chemistry is introduced to the high pressure fluid for treating the substrate surface. The process chemistry comprises fl... | 11/06/2007 |
| 7270789 | Pipettor head having standpipes open at their tops to a pressure/vacuum chamber and method In a preferred embodiment, a pipettor head, including: a body; one or more solenoid valves disposed in the body; each one or more solenoid valves having an outlet at a lower end and an inlet at an upper end; each one or more solenoid valves having an outlet attached... | 09/18/2007 |
| 7259005 | Microorganism having ability to convert sterol into androst-4-ene-3, 17-dione/androsta-1,4-diene-3, 17-dione and preparation method and use thereof Disclosed is a microorganism having an excellent ability to convert sterol into and rost-4-ene-3,17-dione (AD) and androsta-1,4-diene-3,17-dione (ADD), a method for preparation of the microorganism and use thereof, and more particularly, a mutant strain of Mycoba... | 08/21/2007 |
| 7241589 | Method for preparation of androst-4-ene-3,17-dione and androsta-1,4-diene-3,17-dione The present invention relates to a method for preparation of androst-4-ene-3,17-dione (AD) and androsta-1,4-diene-3,17-dione (ADD). More particularly, the present invention relates to a method for preparing AD/ADD, comprising the steps of: (a) heating sterols and em... | 07/10/2007 |
| 7144718 | Saponin-decomposing enzyme, gene thereof and large-scale production system for producing soyasapogenol B The present invention provides a protein having saponin-decomposing activity, more specifically a protein which can decompose a glycoside having soyasapogenol B as an aglycone to produce soyasapogenol B, a polynucleotide encoding such a protein, and a method of prod... | 12/05/2006 |
| 7087402 | Selective transesterification of stanols in mixtures comprising sterols and stanols The present invention is related to a process for selectively transesterifying stanols in mixtures comprising sterols and stanols, and a process for separating sterols from said mixtures. The process of selective transesterification comprises the forming of a... | 08/08/2006 |
| 7078544 | Process for producing sterol or stanol esters by enzymatic transesterification in solvent and water free media A process for producing steryl or stanyl esters, comprises the steps of: a) forming a reacting mixture by contacting a lipase with a reactant mixture wherein the reactant mixture comprise sterols or stanols and one or more esters s... | 07/18/2006 |
| 7045322 | Process for producing lysosphingolipids A process for producing lysosphingolipids by using an enzyme capable of specifically hydrolyzing the acid amide bond between a sphingoid and a fatty acid in a sphingolipid, characterized in that the enzyme reaction is carried out in a two-phase system liquid reactio... | 05/16/2006 |
| 7045148 | Method of collecting placental stem cells A method of collecting embryonic-like stem cells from a placenta which has been treated to remove residual cord blood by perfusing the drained placenta with an anticoagulant solution to flush out residual cells, collecting the residual cells and perfusion liquid fro... | 05/16/2006 |
| 7044662 | Developing photoresist with supercritical fluid and developer An apparatus for developing a polymeric film without the need for a water rinse step is disclosed. An object having a surface supporting a polymeric film is placed onto a support region within a pressure chamber of the apparatus. A fluid and developer is introduced ... | 05/16/2006 |
| 7022508 | Saponin-digesting enzymes, genes thereof and soyasapogenol B mass production system The present invention provides a protein having saponin-decomposing activity, more specifically a protein which can decompose a glycoside having soyasapogenol B as an aglycone to produce soyasapogenol B, a polynucleotide encoding such a protein, and a method of prod... | 04/04/2006 |
| 6933139 | Method for enzymatic splitting of oils and fats Method for the enzymatic splitting of oils and fats for obtaining fatty acids and glycerol by using lipases being added to a mixture containing an oil or fat and water, wherein the splitting reaction is performed only up to a splitting degree at which slowing-down o... | 08/23/2005 |
| 6878535 | Process for producing soyasapogenol B and novel microorganisms An objective of the present invention is to provide a method of producing soyasapogenol B and to provide novel microorganisms. The present invention provides a method of producing soyasapogenol B comprising the steps of culturing microorganisms that belong to genus ... | 04/12/2005 |
| 6828120 | Process to prepare 11β, 17α,21-trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate The present invention is a novel process for the transformation of 17α-hydroxy-6α-methylpregn-4-ene-3,20-dione 17-acetate (I) to 11β,17α,21-trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate (VI) | 12/07/2004 |
| 6660725 | Method and composition for modulating amyloidosis Methods for modulating amyloid deposition in a subject are described. An effective amount of at least one ATP binding cassette (ABC) transporter blocker is administered to a subject, such that modulation of amyloid deposition occurs. Methods also include ... | 12/09/2003 |
| 6632633 | Process for oxidation of steroids and genetically engineered cells used therein An expression cassette, operable in a recombinant host, comprising a heterologous DNA coding sequence encoding a protein, which is functional, alone or in cooperation with one or more additional proteins of catalyzing an oxidation step in the biological p... | 10/14/2003 |
| 6586201 | Method of chromatographic isolation for non-glyceride components A method of chromatographic isolation for non-glyceride components (squalenes, carotenes, vitamin E, sterols and/or the like) from a non-glyceride components-comprising compound by the steps of a. introducing the non-glyceride components-comprising compound on... | 07/01/2003 |
| 6528280 | Process for the preparation of derivatives of ruscus aculeatus steroid glycosides A process for the preparation of desglucodesrhamnoruscin which comprises the hydrolysis of Ruscus Aculeatus steroid glycosides (ruscosaponins) through fermentation of a substrate containing said glycosides by means of fungi of the aspergillus niger specie... | 03/04/2003 |
| 6521600 | Compound, WF002, production thereof and use thereof The present invention provides a new bioactive compound of formula (I), which has an antimicrobial activity against pathogenic microorganisms, and a process for production thereof. Also provided are a pharmaceutical composition comprising the compound and... | 02/18/2003 |
| 6503749 | Yeast strains possessing the interrupted ATF2 gene and their applications A subject of the invention is a modified yeast strain in which the acetyl-CoA pregnenolone acetyltransferase (APAT) activity is eliminated by altering the gene coding for this activity with resultant stabilization of 3ଲ-hydroxysteroids.... | 01/07/2003 |
| 6410759 | Dihydroxycholesterol hydroxylated at 17- and 25-positions A method for preparing at least one hydroxycholesterol chosen from the group consisting of 25-hydroxycholesterol, 17,25-dihydroxycholesterol and 25,26-dihydroxycholesterol by biological hydroxylation of cholesterol, and the aforementioned dihydroxycholest... | 06/25/2002 |
| 6312919 | Process for producing a cholesterol-reduced substance An enzymatic process is presented for reducing the cholesterol level of foods and feeds by converting the cholesterol therein to coprostanol which has a very low intestinal tract absorbability. Cholesterol in meat, egg, milk, seafood and cooked processed ... | 11/06/2001 |
| 6297043 | Mumbaistatin, a process for it's production and its use as a pharmaceutical The present invention relates to a compound named Mumbaistatin, its pharmaceutically acceptable salts and derivatives, a process for its production, and its use as a pharmaceutical. Mumbaistatin is obtainable by cultivation of the microorganism HIL-008003... | 10/02/2001 |
| 6218139 | Yeast strains possessing the interrupted ATF2 gene and their applications A subject of the invention is a modified yeast strain in which the acetyl-CoA pregnenolone acetyltransferase (APAT) activity is eliminated by altering the gene coding for this activity with resultant stabilization of 3ଲ-hydroxysteroids.... | 04/17/2001 |
| 6184043 | Method for detection of specific target cells in specialized or mixed cell population and solutions containing mixed cell populations The invention relates to a method for detecting specific target-cells in a simple and time saving way, using paramagnetic particles, antibodies recognizing the Fc portions of target-cell associating antibodies and target-cell associating antibodies direct... | 02/06/2001 |
| 6146844 | Process for producing hydroxylated cholesterols and dihydroxycholesterols using amycolata A method for preparing at least one hydroxycholesterol chosen from the group consisting of 25-hydroxycholesterol, 17,25-dihydroxycholesterol and 25,26-dihydroxycholesterol by biological hydroxylation of cholesterol, and the aforementioned dihydroxycholest... | 11/14/2000 |
| 6071714 | Process for the microbial conversion of phytosterols to androstenedione and androstadienedione A novel process for the fermentation of phytosterol compositions to androstenedione (androst-4-ene-3,17-dione, AD) and/or androstadienedione (androsta-1,4-diene-3,17-dione, ADD) is disclosed. The process utilizes the micro-organism Mycobacterium MB 3683, ... | 06/06/2000 |
| 5989855 | Bile acid converting microorganism and process for preparing bile acid A microorganism having a capability of introducing a 7ଲ-hydroxyl group into a 7-unsubstituted bile acid, and a process for preparing a bile acid having a 7ଲ-hydroxyl group characterized by bringing the above microorganism into contact with a 7... | 11/23/1999 |
| 5989881 | Nucleic acid molecules encoding delta-5,7-sterol, delta-7 reductase from arabidopsis thaliana A nucleic acid sequence containing a sequence coding for a protein having a delta-5,7 sterol, delta-7 reductase activity, said nucleic acid being a DNA or an RNA, production process, strains of transformed yeasts and uses thereof.... | 11/23/1999 |
| 5919673 | One-pot enzymatic sulfation process using 3'-phosphoadenosine-5'-phosphosulfate and recycled phosphorylated adenosine intermediates A process for the enzymatic synthase of sulfate esters is disclosed in which intermediate phosphorylated adenosine compounds are recycled to minimize enzyme inhibition. Exemplary enzymes include ATP sulfurylase, APS kinase and a sulfotransferase.... | 07/06/1999 |
| 5888821 | Cholesterol derivative for liposomal gene transfer The invention relates to a new cholesterol derivative for liposomal gene transfer. Areas of application of the invention are medicine and genetic engineering. The new cholesterol derivative, 3ଲ(N-(N,N'-dimethylaminoethane)-carbamoyl) cholesterol (DA... | 03/30/1999 |
| 5876993 | Epicholesterol dehydrogenase The present invention relates to a process for producing a cholesterol-reduced substance obtained by converting cholesterol in a substance to epicholesterol, as well as to a novel cholesterol oxidase and a novel epicholesterol dehydrogenase which are used... | 03/02/1999 |
