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An apparatus for the deployment of a visible plume to alert other motorists that a proximate motor vehicle has been involved in a collision.
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| Number | Title | Issue Date |
| 8383408 | Nanofibrillar structure and applications including cell and tissue culture A nanofibrillar structure for cell culture and tissue engineering is disclosed. The nanofibrillar structure can be used in a variety of applications including methods for proliferating and/or differentiating cells and manufacturing a tissue. Also disclosed is an imp... | 02/26/2013 |
| 8293531 | Three-dimensional ex vivo system Disclosed are three-dimensional (3D) systems as may be utilized for ex vivo tissue or cell growth and development. A system generally includes a base material and at least one wicking fiber embedded therein through which a liquid can be spontaneously drawn by capill... | 10/23/2012 |
| 7704740 | Nanofibrillar structure and applications including cell and tissue culture A nanofibrillar structure for cell culture and tissue engineering is disclosed. The nanofibrillar structure can be used in a variety of applications including methods for proliferating and/or differentiating cells and manufacturing a tissue. Also disclosed is an imp... | 04/27/2010 |
| 7622299 | Bioengineered tissue substitutes In one aspect, the invention provides methods for forming a target tissue substitute. The methods of the invention comprise the following steps: (a) providing a scaffold comprising one or more layers of one or more arrays of microfibers, wherein one or more of the a... | 11/24/2009 |
| 7615373 | Electroprocessed collagen and tissue engineering The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or ti... | 11/10/2009 |
| 7354773 | Method and apparatus for preparing cell samples for intracellular antigen detection using flow cytometry A method and apparatus for preparing biological cell samples for intracellular analysis. The invention is based upon the recognition that many of the steps of the conventional methods for such sample preparation can be eliminated, leading to a process that readily l... | 04/08/2008 |
| 7008634 | Cell growth substrates with tethered cell growth effector molecules Described are compositions with tethered growth effector molecules, and methods of using these compositions for growing cells and tissues. Growth effector molecules, including growth factors and extracellular matrix molecules, are flexibly tethered to a solid substr... | 03/07/2006 |
| 6974679 | Support with collagen base for tissue engineering and manufacture of biomaterials The invention relates to a method of in vitro testing of the efficacy of a potentially active substance comprising monitoring the effect of said potentially active substance on an artificial skin, comprising a composite product forming a collagen support comprising ... | 12/13/2005 |
| 6967100 | Pancreatic islet cell growth factors The present invention relates generally to growth factors and more particularly to growth factors which are capable of stimulating or otherwise facilitating formation of insulin-secreting cells. The identification of these growth factors permits the development of p... | 11/22/2005 |
| 6913762 | Stent having non-woven framework containing cells Implantable medical devices that include a non-woven framework are described, as well as methods of using such devices to deliver therapeutic compounds to a patient. ... | 07/05/2005 |
| 6911201 | Method of producing undifferentiated hemopoietic stem cells using a stationary phase plug-flow bioreactor A method of expanding/maintaining undifferentiated hemopoietic stem cells or progenitor cells by obtaining undifferentiated hemopoietic stem cells or progenitor cells; and either seeding the undifferentiated hemopoietic stem cells or progenitor cells into a stationa... | 06/28/2005 |
| 6780612 | Methods for the propagation of lytic organisms The present invention provides a method for the propagation of lytic organisms which comprises the infection of the cells of a stable cell line within a hollow fibre bioreactor with a lytic organism, wherein after said infection, said organism multiplies within the ... | 08/24/2004 |
| 6670179 | Molecular functionalization of carbon nanotubes and use as substrates for neuronal growth A cell and substrate system and nerve regeneration implant are disclosed including a carbon nanotube and a neuron growing on the carbon nanotube. Both unfunctionalized carbon nanotubes and carbon nanotubes functionalized with a neuronal growth promoting a... | 12/30/2003 |
| 6627422 | Device containing cell-supporting yarn matrix encapsulated in a semi-permeable membrane A device is provided containing cells or tissue distributed on a filamentous cell-supporting matrix which is encapsulated by a semi-permeable membrane which can be immunoisolatory. The matrix may be formed of a plurality of monofilaments twisted into yarn... | 09/30/2003 |
| 6616912 | Bi-component microporous hollow fiber membrane structure for in vivo propagation of cells A bi-component microporous hollow fiber membrane structure is provided for in vivo propagation of cells and use in testing of the effect of medical treatments on cells within the structure. The structure has an inner structure fabricated from a first bio-... | 09/09/2003 |
| 6541023 | Use of collagen of aquatic origin for the production of supports for tissue engineering, and supports and biomaterials obtained Use of collagen of aquatic origin for the production of supports for tissue engineering is disclosed. The collagen may be obtained from fish skin, preferably in its native form. Novel tissue engineering supports with a low risk of contamination are produc... | 04/01/2003 |
| 6482645 | Methods and compositions for producing artificial fascia The present invention describes methods for producing artificial fascial slings and their subsequent use in treating subjects with urinary incontinence. The invention is based, in part, on the discovery that mesenchymal cells that secrete elastin and coll... | 11/19/2002 |
| 6368859 | Methods and compositions for producing a fascial sling The present invention describes methods for producing artificial fascial slings and their subsequent use in treating subjects with urinary incontinence. The invention is based, in part, on the discovery that mesenchymal cells that secrete elastin and coll... | 04/09/2002 |
| 6309635 | Seeding parenchymal cells into compression resistant porous scaffold after vascularizing in vivo A method is provided whereby cells having a desired function are seeded on and into biocompatible, biodegradable or non-degradable porous polymer scaffolding matrix, previously implanted in a patient and infiltrated with blood vessels and connective tissu... | 10/30/2001 |
| 6303136 | Cells or tissue attached to a non-degradable filamentous matrix encapsulated by a semi-permeable membrane A device is prepared having cells or tissue attached to a non-degradable filamentous matrix surrounded by a semi-permeable membrane. The matrix is preferably formed of a plurality of monofilaments twisted into a yarn or woven into a mesh, and can be in th... | 10/16/2001 |
| 6228607 | Bioreactor The invention relates to a bioreactor for a cell treatment of a medium. Said bioreactor comprises an element defining a chamber in which cells for treating the medium are located, a liquid permeable membrane separating the said chamber from a first channe... | 05/08/2001 |
| 6140039 | Three-dimensional filamentous tissue having tendon or ligament function A stromal cell-based three-dimensional cell culture system is provided which can be used to culture a variety of different cells and tissues in vitro for prolonged periods of time. The stromal cells along with connective tissue proteins naturally secreted... | 10/31/2000 |
| 6051425 | Method for producing tissue formation and tissue culture kit A matrix for tissue culture comprising two kinds of sponges having at least one different physical property and/or at least one different chemical property; a method for culturing tissue using said matrix for tissue culture comprising inoculating and cult... | 04/18/2000 |
| 6045818 | Cell growth substrates with tethered cell growth effector molecules Disclosed are compositions with tethered growth effector molecules, and methods of using these compositions for growing cells and tissues. Growth effector molecules, including growth factors and extracellular matrix molecules, are flexibly tethered to a s... | 04/04/2000 |
| 6043079 | Cell growth apparatus for histophysiologic culture The present invention provides an apparatus and methods for incubating cells which rely on the use of a semipermeable membrane placed between two planar members, at least one planar member having an aperture.... | 03/28/2000 |
| 6022743 | Three-dimensional culture of pancreatic parenchymal cells cultured living stromal tissue prepared in vitro A stromal cell-based three-dimensional cell culture system is prepared which can be used to culture a variety of different cells and tissues in vitro for prolonged periods of time. The stromal cells and connective tissue proteins naturally secreted by the... | 02/08/2000 |
| 5998184 | Basket-type bioreactor Improved hollow fiber bioreactor systems and cell culture methods are described. The improvement includes means which may be a novel basket bioreactor for extending the extracapillary space of a conventional hollow fiber bioreactor.... | 12/07/1999 |
| 5976878 | Method and apparatus for preparing composite skin replacement A method and apparatus for forming a permanent, composite skin replacement consisting of an epidermal component and a porous, resorbable, biosynthetic laminated dermal membrane component for use in wound repair. The dermal membrane is formed in the appara... | 11/02/1999 |
| 5943821 | Process for packaging plant tissues cultured in vitro for transport Plant tissues which have been cultured in vitro are packaged with a nutritive medium for survival of the tissues in a sealed sterile container and with support members so that the plant tissues are positioned between surfaces of the support members. The s... | 08/31/1999 |
| 5942436 | Culturing liver cells A method for maintaining hepatocytes in culture includes providing the hepatocytes with a support, the support including extracellular matrix, the support having a configuration that permits each of at least a portion of the hepatpocytes to form at least ... | 08/24/1999 |
| 5906828 | Cell growth substrates with tethered cell growth effector molecules Disclosed are compositions with tethered growth effector molecules, and methods of using these compositions for growing cells and tissues. Growth effector molecules, including growth factors and extracellular matrix molecules, are flexibly tethered to a s... | 05/25/1999 |
| 5902577 | Insulin-secreting cell lines, methods of production and use The invention relates to the field of biology and, in particular, to the field of cellular biology. The invention concerns a novel glucose-sensitive cell line designated ଲ cell line (INS-I) expressing glucokinase and the glucose carrier Glut 2 at le... | 05/11/1999 |
| 5863531 | In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework A stromal cell-based three-dimensional cell culture system is provided which can be used to culture a variety of different cells and tissues in vitro for prolonged periods of time. The stromal cells along with connective tissue proteins naturally secreted... | 01/26/1999 |
| 5858721 | Three-dimensional cell and tissue culture system The present invention relates to a three-dimensional cell culture system which can be used to culture a variety of different cells and tissues in vitro for prolonged periods of time. In accordance with the invention, cells derived from a desired tissue ar... | 01/12/1999 |
| 5849588 | Methods of use of a three-dimensional liver cell and tissue culture system The present invention relates to a three-dimensional cell and tissue culture system. In particular, it relates to this culture system for the long term culture of liver cells and tissues in vitro in an environment that more closely approximates that found... | 12/15/1998 |
| 5804178 | Implantation of cell-matrix structure adjacent mesentery, omentum or peritoneum tissue A matrix structure containing attached cells such as endocrine cells, fibroblasts, endothelial cells or genitourinary cells is implanted in a patient adjacent tissue having a high surface area and vasculature such as mesentery, omentum or peritoneum tissu... | 09/08/1998 |
| 5780281 | Method of preparing a low-density porous fused-fiber matrix A method is provided for preparing a low density porous rigid fused-fiber matrix having a density of between about 3.5 and 5.5 pounds/cubic foot and a free volume of between about 90-98 volume percent for use as a cell-culture substrate or implant materia... | 07/14/1998 |
| 5770193 | Preparation of three-dimensional fibrous scaffold for attaching cells to produce vascularized tissue in vivo Fibers of a biocompatible, biodegradable or non-biodegradable, synthetic polymer are provided, and are formed into a three-dimensional scaffold. The fibers of the scaffold may have a branched configuration extending outwardly from a central stem. The fibe... | 06/23/1998 |
| 5770417 | Three-dimensional fibrous scaffold containing attached cells for producing vascularized tissue in vivo A cell-scaffold composition is prepared in vitro for implanting to produce functional organ tissue in vivo. The scaffold is three-dimensional and is composed of hollow or solid fibers of a biocompatible, synthetic polymer which is biodegradable or non-bio... | 06/23/1998 |
| 5766584 | Inhibition of vascular smooth muscle cell proliferation with implanted matrix containing vascular endothelial cells A composition and method are provided for inhibition of vascular smooth muscle cell proliferation following injury to the endothelial cell lining of a blood vessel such as resulting from angioplasty, vascular bypass surgery or organ transplantation. The c... | 06/16/1998 |
