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| Number | Title | Issue Date |
| 7393685 | Method for cultivating cancer cells from human tissue and device for preparing tissue samples The invention relates to a method for cultivating cancer cells for scientific serial assays, wherein a tissue sample which is heterogeneous with respect to contaminants, normal cells and tumor cells is locally separated in a sequential-parallel splitting method. The... | 07/01/2008 |
| 7335811 | Method for collecting cells in M phase or Gphase and method for nuclear transplantation using the cells Methods for collecting cells in M phase or G1 phase, by which the percentage of M phase or G1 phase cells is higher than that attained by the conventional methods are disclosed. ... | 02/26/2008 |
| 7303912 | Cultures of GFAP nestin cells that differentiate to neurons Cultures of cells immunoreactive for glial fibrillary acidic protein (GFAP), as well as for the intermediate filament marker nestin were grown in a medium including epidermal growth factor (EGF) and serum. The cultured cells had the morphology of astroglial cells. T... | 12/04/2007 |
| 7300789 | Bioreactor forming a rigid vessel The invention provides a bioreactor (10) for the culture of animal, vegetable, microbial of algal cells of their co-cultures, of the type including a body (12) which delimits an internal volume (14) capable of holding a culture liquid (16) and a gas volume (17) abov... | 11/27/2007 |
| 7279330 | Method for identifying modulating compounds of neurotransmitters A process for identifying compounds that can modulate the release of neuromediators is described in which, for example, at least one compound that is to be tested is brought into contact with a nerve tissue preparation and the possible modulating effect of the compo... | 10/09/2007 |
| 7192768 | Synchronization of the cytoplasmatic and the nuclear maturation of oocytes The present invention relates to a method for in vitro maturation of oocytes comprising the steps of: (a) culturing one or more GV oocytes in a culture medium, the culture medium comprising a nuclear maturation inhibiting substance and comprising one or... | 03/20/2007 |
| 7186558 | Keratinocytes obtained from embryonic stem cells of mammals The present invention relates to a method for inducing the differentiation of mammals' embryonic stem cells into keratinocytes, comprising the following steps of: isolating an extracellular matrix secreted by at least one mammals' ... | 03/06/2007 |
| 7109028 | Methods of isolating hepatic progenitors This invention relates to methods of isolating hepatoblasts utilizing panning techniques and fluorescence activated cell sorting. This invention further relates to isolated hepatoblasts and to a method of treating liver dysfunction as well as to methods of forming a... | 09/19/2006 |
| 7101545 | Method for using human intervertebral disc cells There is provided a method for growing human intervertebral cells. Disc tissue is surgically removed from a normal disc of a patient, the cells expanded by feeding with a cell stimulant such as a growth factor, or a cytokine or a bioactive agent to form monolayer pr... | 09/05/2006 |
| 7088111 | Enhanced isolation level between sampling channels in a vector network analyzer A system and method for providing improved isolation between sampling channels in a vector network analyzer and sampling circuit. A vector network analyzer sampling channel includes a non-linear transmission line, an isolation device, a band-pass filter, and a sampl... | 08/08/2006 |
| 7045349 | Method of islet isolation using process control Advanced Islet Separation Technology incorporates an automated method, automated control methodology, process control interface, and automated apparatus to separate (isolate) and process pancreatic islets in a tissue suspension in physiologic process solution, utili... | 05/16/2006 |
| 6960447 | Isolation of membrane bound ligand-specific complexes A method to recover receptors without removing microenvironmental components associated with them is described. The membranes containing the receptors are first associated with ligand-coupled solid supports to achieve association of the membranes through a receptor/... | 11/01/2005 |
| 6946293 | Progenitor cells, methods and uses related thereto The present invention relates to a substantially pure population of viable pancreatic progenitor cells, and methods for isolating such cells. The present invention further concerns certain therapeutic uses for such progenitor cells, and their progeny. ... | 09/20/2005 |
| 6908766 | Device and method for capturing biological tissues A device and method for capturing a biological tissue, comprises cutting a minute biological cellular tissue using a contactless cutting apparatus, wherein, by inverting a biological tissue slide provided with a sample thereon, and after cutting a cellular tissue pr... | 06/21/2005 |
| 6900051 | Process for obtaining mammalian insulin secreting cells in vitro and their uses The present invention relates to a process for obtaining mammalian insulin secreting cells in vitro, characterized in that it contains the following steps: a) preparation of the mammalian pancreatic tissues by removal of a pancreas, b) dissociation of the pancreatic... | 05/31/2005 |
| 6833270 | Apparatus and method for isolating cells from organs An apparatus and method for extracting cells from organs in which a digestion chamber includes at least one inlet and at least one outlet, and a separator for retaining the organ and permitting the cells and the physiologically compatible medium to exit the outlet. ... | 12/21/2004 |
| 6753181 | Methods and compositions for organ decellularization The invention is directed to methods for producing a decellularized organ or part of an organ. A decellularized organ is produced using an isolated organ mechanically agitated to remove cellular membranes surrounding the isolated organ without destroying the interst... | 06/22/2004 |
| 6664106 | Production of primmorphs from disassociated cells of sponges and corals This invention relates to the establishment of a novel method of culturing sponge cells, coral cells and cells from other invertebrates in vitro. The cells cultured in vitro, which can be cultured as units similar to aggregates, are referred to as primmor... | 12/16/2003 |
| 6585969 | Non-viable keratinocyte cell composition or lysate for promoting wound healing Cultures of keratinocyte cells are provided which are free from nonautologous fibroblasts and organ extracts, and which have a high speed of cell amplification for a minimum seeding density. The cultures can be cryopreserved in a buffered isotonic medium ... | 07/01/2003 |
| 6506576 | Serum-and steroid-free culture media for cerebellar granule neurons The invention is a system for maintenance and high-throughput analysis of cerebellar granule neurons in tissue culture plates under chemically defined conditions. The invention includes serum-free granule culture medium, which is composed of high glucose ... | 01/14/2003 |
| 6489164 | Isolation of cells from organ tissue using sonication A method for isolating specific viable cell types from surrounding organ tissue is provided. The method entails the use of sonication in conjunction with tissue dissociating agents to free the cells of interest. A specific application of the method is the... | 12/03/2002 |
| 6383805 | Epithelial cell cultures for in vitro testing A method and a medium for culturing epithelial cells of both normal and malignant origin is provided. The method entails physically disaggregating tissue samples, placing the resulting fragments onto a surface comprised of basement membrane matrix compone... | 05/07/2002 |
| 6376244 | Methods and compositions for organ decellularization The invention is directed to methods for producing a decellularized organ or part of an organ. A decellularized organ is produced using an isolated organ mechanically agitated to remove cellular membranes surrounding the isolated organ without destroying ... | 04/23/2002 |
| 6294383 | Porcine neural cells and their use in treatment of neurological deficits due to neurodegenerative diseases Porcine neural cells and methods for using the cells to treat neurological deficits due to neurodegeneration are described. The porcine neural cells are preferably embryonic mesencephalic, embryonic striatal cells, or embryonic cortical cells. The porcine... | 09/25/2001 |
| 6242252 | Hepatic progenitors and method of isolating same This invention relates to methods of isolating hepatic progenitors utilizing panning techniques and fluorescence activated cell sorting. This invention further relates to isolated hepatic progenitors and to a method of treating liver dysfunction as well a... | 06/05/2001 |
| 6117675 | Retinal stem cells The invention relates to stem cells isolated from the retina of mammals and retinal cells differentiated from these stem cells. The invention also relates to a method of isolating retinal stem cells and inducing retinal stem cells to produce retinal cells... | 09/12/2000 |
| 6107543 | Culture of totipotent embryonic inner cells mass cells and production of bovine animals The use of totipotent embryonic stem cells to provide substantially identical cells for embryo cloning techniques is described. The method includes the culture of loose suspensions of inner cell mass cells of bovine animals to retrieve large populations o... | 08/22/2000 |
| 6080579 | Method for producing human intervertebral disc cells There is provided a method for growing human intervertebral cells. Disc tissue is surgically removed from a normal disc of a patient, the cells expanded by feeding with a cell stimulant such as a growth factor, or a cytokine or a bioactive agent to form m... | 06/27/2000 |
| 6054314 | Method for collecting cells from internal organs A substantially non-invasive and efficient method for collecting cells from the internal organs of a subject is provided. In one embodiment, energy from an external energy source is applied to the subject that is sufficient to loosen the cells from an int... | 04/25/2000 |
| 6017760 | Isolation and culture of porcine hepatocytes A perfusion device such as a liver assist device containing a housing defining a perfusion inlet and a perfusion outlet, a porous membrane structure mounted within said housing to define a perfusion compartment and an adjacent hepatocyte compartment, and ... | 01/25/2000 |
| 5994619 | Production of chimeric bovine or porcine animals using cultured inner cell mass cells Novel cultured inner cell mass (CICM) cells, and cell lines, derived from ungulates, in particular, pigs and cows, and methods for their preparation are provided. The subject CICMs possess similar morphology and express cell markers identically or substan... | 11/30/1999 |
| 5965541 | Vectors and methods for gene transfer to cells The present invention provides a chimeric adenovirus coat protein, which differs from the wild-type coat protein by the introduction of a nonnative amino acid sequence. Such a chimeric adenovirus coat protein according to the invention is able to direct e... | 10/12/1999 |
| 5962324 | Three dimensional optic tissue culture and process A process for artificially producing three-dimensional optic tissue has been developed. The optic cells are cultured in a bioreactor at low shear conditions. The tissue forms as normal, functional tissue grows with tissue organization and extracellular ma... | 10/05/1999 |
| 5905042 | Cultured inner cell mass cell lines derived from bovine or porcine embryos Novel cultured inner cell mass (CICM) cells, and cell lines, derived from ungulates, in particular, pigs and cows, and methods for their preparation are provided. The subject CICMs possess similar morphology and express cell markers identically or substan... | 05/18/1999 |
| 5900374 | Cell culture harvesting device The invention concerns a cell culture harvesting device consisting of a scraper head with a blade and a guide strip, the scraper head and the guide strip being connected with one another only by magnetic attraction. The magnetic attraction is achieved by ... | 05/04/1999 |
| 5879939 | Isolation of cells from organ tissue using sonication A method for isolating specific viable cell types from surrounding organ tissue is provided. The method entails the use of sonication in conjunction with tissue dissociating agents to free the cells of interest. A specific application of the method is the... | 03/09/1999 |
| 5866167 | Non-viable total keratinocyte lysate for promoting wound healing Cultures of keratinocyte cells are provided which are free from nonautologous fibroblasts and organ extracts, and which have a high speed of cell amplification for a minimum seeding density. Preferably, a culture contains no more than about 10% autologous... | 02/02/1999 |
| 5801151 | Estimation of ovular fiber production in cotton The present invention is a method for rendering cotton fiber cells that are post-anthesis and pre-harvest available for analysis of their physical properties. The method includes the steps of hydrolyzing cotton fiber cells and separating cotton fiber cell... | 09/01/1998 |
| 5744363 | Method for establishing a tumor-cell line by preparing single-cell suspension of tumor cells from tumor biopsies The present invention provides a novel method for the establishment of tumorigenic cell lines from biopsies of human or animal tumors. The method includes preparing a single-cell suspension of a tumor cells by injecting cell culture medium into an isolate... | 04/28/1998 |
| 5721120 | Method of disrupting cultured cells using an impinging jet device A novel method of disrupting cells which do not have a cell wall comprises passing suspended cells through a low pressure impinging jet device. This method disrupts the cells, but does not harm the cell products which are liberated.... | 02/24/1998 |
