Bizarre Patents
Crispy Chip Sandwich and Process of Producing a Sandwich Product
A food product comprising a multilayer cookie or snack having outer layers formed from a crispy type edible food product such as a potato chip or corn chip, etc. with an intermediate marshmallow layer being in contact with the inner surface of each crispy chip and one or more filler substances.
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| Number | Title | Issue Date |
| 8110399 | Stem cells of the islets of langerhans and their use in treating diabetes mellitus Methods and compositions are described for the treatment of type I insulin-dependent diabetes mellitus and other conditions using newly identified stem cells that are capable of differentiation into a variety of pancreatic islet cells, including insulin-producing be... | 02/07/2012 |
| 8084254 | Human blood brain barrier model The present invention relates to an immortalized human brain endothelial cell line that is useful as an in vitro model of the blood brain barrier. ... | 12/27/2011 |
| 8039255 | Compositions and methods for inhibiting cell migration The finding that Dickkopf1 (Dkk1) is a dual function protein demonstrates a mechanism for the coordination of cell migration and antagonism of Wnt/β-catenin signaling during developmental and pathological processes. The profile of Dkk proteins expressed by human br... | 10/18/2011 |
| 7993916 | Methods for increasing definitive endoderm production Disclosed herein are methods for increasing the production of definitive endoderm cells from pluripotent stem cells. Also disclosed herein are agents capable of increasing definitive endoderm cell production. ... | 08/09/2011 |
| 7985585 | Preprimitive streak and mesendoderm cells This disclosure relates to compositions comprising human preprimitive streak cells and/or human mesendoderm cells as well as methods for their production. Additionally, disclosed herein are methods of identifying factors useful in the further differentiation of prep... | 07/26/2011 |
| 7985586 | Oligodendrocyte precursor cell composition and methods of use The present invention provides a cell culture enriched for sphingolipid enhances neural stem cells (SENSe), particularly oligodendrocyte precursor cells (ODPCs), that do not form teratomas after transplanted in vivo. Methods for producing and use of the invention OD... | 07/26/2011 |
| 7968336 | Methods of isolation, expansion and differentiation of fetal stem cells from chorionic villus, amniotic fluid, and placenta and therapeutic uses thereof The present invention is directed to pluripotent fetal stem cells derived from chorionic villus, amniotic fluid, and placenta and the methods for isolating, expanding and differentiating these cells, and their therapeutic uses such as manipulating the fetal stem cel... | 06/28/2011 |
| 7955850 | Stem cells obtained from pulp of deciduous or permanent teeth and of dental germ, able to produce human bone tissue In this invention is described a method that foresees the isolation of a new subpopulation of stem cells derived form dental pulp, whose differentiation is osteoblasts lead to the subsequent production and employment of a bone tissue, called LAB (Living Autologous B... | 06/07/2011 |
| 7923244 | Artificial cartilage tissue and production method thereof To obtain an artificial cartilage tissue having high strength and biocompatibility. There is provided an artificial cartilage tissue which is substantially free of heterologous protein and is substantially free of scaffold derived from non-cartilage-derived cells, b... | 04/12/2011 |
| 7906330 | Two cell population comprising chondrocyte precursors and human embryonic stem cells This invention provides a system for obtaining cells of the chondrocyte lineage by differentiating primate pluripotent stem cells. The process involves culturing the cells as a micromass or other aggregate form in a cocktail of differentiation agents that facilitate... | 03/15/2011 |
| 7883891 | Unique properties of stem cells The present invention is directed to unique properties of stem cells, including methods to identify stem cell markers by identifying molecules associated specifically with chromosomes in stem cells. More particularly, we have discovered that somatic stem cells repea... | 02/08/2011 |
| 7883892 | Swine multipotent adult progenitor cells The present invention provides swine cells of non-embryonic origin that can be maintained in culture in the undifferentiated state or differentiated to form cells of multiple cell types. Also provided are methods of isolation and culture, as well as uses for the cel... | 02/08/2011 |
| 7833788 | Production of vaccines Means and methods are provided for the production of mammalian viruses comprising: infecting a culture of immortalized human cells with the virus, incubating the culture infected with virus to propagate the virus under conditions that permit growth of the virus, and... | 11/16/2010 |
| 7811817 | Establishment of a human embryonic stem cell line using mammalian cells Purified preparations of human embryonic stem cells with certain population-specific characteristics are disclosed. This preparation is characterized by the positive expression of the following pluripotent cell surface markers: SSEA-1 (−); SSEA-4 (+); TRA-1-60 (+)... | 10/12/2010 |
| 7807461 | Multipotent stem cells derived from human adipose tissue and cellular therapeutic agents comprising the same This invention relates to human adipose tissue-derived multipotent adult stem cells. More particularly, the invention relates to human adipose tissue-derived multipotent stem cells, which can be maintained in an undifferentiated state for a long period of time by fo... | 10/05/2010 |
| 7776591 | Hematopoietic stem cells treated by in vitro fucosylation and methods of use A method of in vitro fucosylation of selectin ligands on cord blood-derived hematopoietic stem cells for bone marrow transplantation is disclosed. In this method, an effective amount of an α1,3-fucosyltransferase, e.g., α1,3-fucosyltransferase VI, is used in vitro... | 08/17/2010 |
| 7767452 | Tissue treatments with adipocyte cells Certain embodiments here in are directed to a method of treating a tissue associated with a defect in a human including wrinkles, rhytids, depressed scar, cutaneous depressions, stretch marks, hyperplasia of the lip, nasolabial fold, melolabial fold, scarring from a... | 08/03/2010 |
| 7763461 | Antitumor vaccination using allogeneic tumor cells expressing alpha (1,3)-galactosyl transferase The invention relates to methods and compositions for causing the selective targeting and killing of tumor cells. Through ex vivo gene therapy protocols tumor cells are engineered to express an α (1,3) galactosyl epitope. The cells are then irradiated or otherwise ... | 07/27/2010 |
| 7745216 | Methods and reagents for treating glucose metabolic disorders The invention relates to methods for potentiating, enhancing or restoring glucose responsivity in pancreatic islets or cells. The methods can be used as therapies for diseases caused by, or coincident with, aberrant glucose metabolism, such as Type II Diabetes Melli... | 06/29/2010 |
| 7732199 | Process for making transplantable cardiomyocytes from human embryonic stem cells This invention provides populations human cells of the cardiomyocyte lineage. The cells are obtained by causing cultures of pluripotent stem cells to differentiate in vitro, and then harvesting cells with certain phenotypic features. Differentiated cells bear cell s... | 06/08/2010 |
| 7723107 | Pharmaceutical composition for inducing an immune response in a human or animal The present invention relates to a pharmaceutical composition for inducing an immune response in a human or animal, comprising dendritic cells loaded with at least five cancer/testis antigen and no lineage specific differentiation antigens or substantially no lineag... | 05/25/2010 |
| 7695963 | Methods for increasing definitive endoderm production Disclosed herein are methods for increasing the production of definitive endoderm cells from pluripotent stem cells. Also disclosed herein are agents capable of increasing definitive endoderm cell production. ... | 04/13/2010 |
| 7678570 | Human cell strains for protein production, provided by selecting strains with high intracellular protein and mutating with carcinogens A novel human cell strain enabling the continuous production of a desired protein with high efficiency, comprising a novel human cell strain established by transforming a human cell strain whose total intracellular protein weight is 0.1 to 1 mg per 1,000,000 cells; ... | 03/16/2010 |
| 7659118 | Multipotent adult stem cells The invention provides isolated stem cells of non-embryonic origin that can be maintained in culture in the undifferentiated state or differentiated to form cells of multiple tissue types. Also provided are methods of isolation and culture, as well as therapeutic us... | 02/09/2010 |
| 7642091 | Human trophoblast stem cells and use thereof Existence of human trophoblast stem (hTS) cells has been suspected but unproved. The isolation of hTS cells is reported in the early stage of chorionic villi by expressions of FGF4, fgfr-2, Oct4, Thy-1, and stage-specific embryonic antigens distributed in different ... | 01/05/2010 |
| 7638328 | Method for efficient transfer of human blastocyst-derived stem cells (hBS cells) from a feeder-supported to a feeder-free culture system, long-term propagation of hBS cells under feeder-free conditions and use of cultured hBS cells for applications in myocardial regeneration A method for the transfer of human blastocyst-derived stem cells (hBS cells) to feeder-free culture system and propagation of the cells in such a feeder-free culture system, the method comprising the following steps of (a) transferring the balstocyst-derived stem ce... | 12/29/2009 |
| 7585672 | Differentiation of stem cells to endoderm and pancreatic lineage Methods are described to increase the proportion of endoderm committed cells and pancreatic lineage cells in a culture of human embryonic stem cells which are undergoing differentiation. The method also results in a stem cell derived cell culture which does not have... | 09/08/2009 |
| 7582479 | Primate embryonic stem cell line A purified preparation of primate embryonic stem cells is disclosed. This preparation is characterized by the following cell surface markers: SSEA-1 (−); SSEA-4 (+); TRA-1-60 (+); TRA-1-81 (+); and alkaline phosphatase (+). In a particularly advantageous embodimen... | 09/01/2009 |
| 7575924 | Methods and compositions relating to improved lentiviral vectors and their applications The present invention provides HIV-derived lentivectors which are safe, highly efficient, and very potent for expressing transgenes for human gene therapy, especially, in human hematopoietic progenitor cells as well as in all other blood cell derivatives. The lentiv... | 08/18/2009 |
| 7514259 | Isolation and transplantation of retinal stem cells The present invention relates to the isolation, in vitro propagation, and transplantation and integration of non-pigmented retinal stem cells derived from the neuroretina of the eye, ex vivo and in vivo. ... | 04/07/2009 |
| 7510876 | Definitive endoderm Disclosed herein are cell cultures comprising definitive endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified definitive endoderm cells as well as methods for enriching, isolating and purifyin... | 03/31/2009 |
| 7442548 | Culturing human embryonic stem cells in medium containing pipecholic acid and gamma amino butyric acid Previous methods for culturing human embryonic stem cells have required either fibroblast feeder cells or a medium which has been exposed to fibroblast feeder cells in order to maintain the stem cells in an undifferentiated state. It has now been found that if high ... | 10/28/2008 |
| 7439060 | Independent helper virus packaging cell line for propagating viral vectors Provided are novel vectors and viral vectors capable of expressing exogenous gene or exogenous nucleic acid sequences in a target cell of interest, such as T cells, bone marrow cells, epithelial cells, liver cells and the like. The nucleic acid components of the vec... | 10/21/2008 |
| 7439064 | Cultivation of human embryonic stem cells in the absence of feeder cells or without conditioned medium The invention relates to methods for culturing human embryonic stem cells by culturing the stem cells in an environment essentially free of mammalian fetal serum and in a stem cell culture medium including amino acids, vitamins, salts, minerals, transferring, insuli... | 10/21/2008 |
| 7439327 | Stem cell factor-like proteins and uses thereof The invention relates to pharmaceutical compositions comprising gastrointestinal proliferative factor SCFA2, SCFA4 or SCFA4v polynucleotides and polypeptides. The invention further relates to the therapeutic use of SCFA2, SCFA4 or SCFA4v to prevent or ... | 10/21/2008 |
| 7431932 | Reovirus clearance of ras-mediated neoplastic cells from mixed cellular compositions Reovirus can be used to selectively remove ras-mediated neoplastic cells from a cellular composition. It is of particular interest to purge autographs which may contain neoplastic cells with reovirus before transplanting the autographs back into the recipient, there... | 10/07/2008 |
| 7432104 | Methods for the culture of human embryonic stem cells on human feeder cells Methods and cell culture medium for the generation of human pluripotent embryonic stem cells are disclosed. Human embryonic stem cells are cultured with human granulosa feeder cells, muscle cells, Fallopian ductal epithelial cells, bone marrow stromal cells, and ski... | 10/07/2008 |
| 7429488 | Method for processing lipoaspirate cells Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a ... | 09/30/2008 |
| 7425448 | Cardiomyocyte precursors from human embryonic stem cells This invention provides populations human cells of the cardiomyocyte lineage. The cells are obtained by causing cultures of pluripotent stem cells to differentiate in vitro, and then harvesting cells with certain phenotypic features. Differentiated cells bear cell s... | 09/16/2008 |
| 7425410 | Methods for diagnosing a bipolar disorder and unipolar disorder Changes that occur in Na+K+ ATPase regulation and therefore in the membrane potential in cells from bipolar individuals, as compared to cells from unaffected control individuals, are utilized to provide a diagnostic assay for a bipolar disorder. The diagnostic assay... | 09/16/2008 |
