Celebrity Inventors
Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 8043852 | Monoclonal antibody specific to dentin-derived heparan sulfate The present invention provides a monoclonal antibody displaying excellent specificity against heparan sulfate saccharide chains for the analysis of heparan sulfate saccharide chains specific to dentin. The invention also provides a method of evaluating reproductive ... | 10/25/2011 |
| 7842500 | Anti-heparan sulfate antibody, method for detection of heparan sulfate, and kit for detection of heparan sulfate An antibody which reacts with N-acetylheparosan and heparan sulfate that is derived from bovine kidney but does not substantially react with heparan sulfate derived from a murine Engelbreath-Holm-Swarn tumor tissue, the antibody being produced with a hybridoma which... | 11/30/2010 |
| 7510875 | Methods for producing purified adenoviral vectors The present invention addresses the need to improve the yields of viral vectors when grown in cell culture systems. In particular, it has been demonstrated that for adenovirus, the use of low-medium perfusion rates in an attached cell culture system provides for imp... | 03/31/2009 |
| 7435585 | Auto-stimulating cells and methods for making and using the same Methods for transferring one or more proteins to a cell are disclosed. The protein or proteins to be transferred are in the form of a fusion protein, and contain at least one domain encoding for a protein or peptide having trans signaling and/or adhesion function. T... | 10/14/2008 |
| RE39760 | Monoclonal antibodies against human colon carcinoma-associated antigens and uses therefor Monoclonal antibodies, in particular 33.28 and 31.1, and chimeric antibodies, in particular mouse/humans chimeric Chi #1 specific for glycoprotein antigens of colon carcinoma-associated antigens which are immunogenic in humans, are disclosed. Such antibodies, and fr... | 08/07/2007 |
| 7175989 | Antibodies to trisulfated heparin disaccharide in painful sensory axonal neuropathy Methods aiding in the diagnosis of certain painful, predominantly sensory, polyneuropathies are disclosed, in which the amount of antibodies to trisulfated disaccharide is assessed in a test sample. Also disclosed are kits that can be used in the methods of the inve... | 02/13/2007 |
| 7056702 | Detecting lipocalin The invention provides antibodies reactive with distinct lipocalin epitopes that are useful for detecting inflammation and bacterial infections in mammals. ... | 06/06/2006 |
| 7038018 | Antibodies and ligands for “Bonzo” chemokine receptor The invention relates to an antibody or antigen-binding fragment thereof which binds to the CXC chemokine receptor Bonzo (also referred to as STRL33, TYMSTR, HBMBU14 and CXCR6) and blocks the binding of a ligand (e.g., SExCkine (also referred to as chemokine alpha-5... | 05/02/2006 |
| 6900302 | Vaccine formulations comprising antiidiotypic antibodies which immunologically mimic group B streptococcal carbohydrates The invention relates to peptide, oligopeptide or polypeptide compounds that are capable of eliciting a protective immune response against the capsular polysaccharide of group B Streptococcus (GBS), particularly type III GBS. Such compounds are useful in the ... | 05/31/2005 |
| 6884417 | Monoclonal antibodies immunoreactive with lipopolysaccharide binding protein (LBP) and methods of their use The present invention concerns a method of treating LBP-mediated LPS-induced myeloid cell activation comprising administering a therapeutically effective amount of an anti-LBP monoclonal antibody molecule. A therapeutic composition comprising anti-LBP antibody molec... | 04/26/2005 |
| 6884878 | Neuropeptides and their use for pest control The present invention discloses novel pest control compounds comprising NPF polypeptides and methods for using such compounds in the control of pests. ... | 04/26/2005 |
| 6825324 | Antibodies to receptor protein tyrosine kinases The protein tyrosine kinase receptors, designated Rse and HPTK6, have been purified from human and/or murine cell tissues. Rse and HPTK6 have been cloned from a cDNA library of a human liver carcinoma cell line (i.e., Hep 3B) using PCR amplification. Provided herein... | 11/30/2004 |
| 6808877 | Ligands for FPR class receptors that induce a host immune response to a pathogen or inhibit HIV infection The present invention relates to the discovery of molecules that inhibit viral infection and promote a host immune response to a pathogen. More specifically, the invention disclosed herein concerns molecules that interact with a FPR class receptor, inhibit HIV infec... | 10/26/2004 |
| 6803039 | Human monoclonal antibody against a costimulatory signal transduction molecule AILIM Immunization of human antibody-producing transgenic mice, which have been created using genetic engineering techniques, with AILIM molecule as an antigen resulted in various human monoclonal antibodies capable of binding to AILIM and capable of controlling a variety... | 10/12/2004 |
| 6730307 | Anti-cryptosporidium parvum preparations Compositions and methods useful for conferring passive or active immunity to the parasite, C. parvum. A high molecular weight glycoprotein antigen isolated from C. parvum, capable of binding the mAb 3E2, was shown to harbor an epitope critical for trig... | 05/04/2004 |
| 6720156 | Superficial zone protein-binding molecules and uses thereof The invention provides an antibody or a fragment thereof having specific binding affinity for superficial zone protein (SZP) or a variant, fragment, or protein core thereof, wherein the binding affinity of the antibody or fragment thereof for human superficial zone ... | 04/13/2004 |
| 6682737 | Anti-cryptosporidium parvum preparations Compositions and methods useful for conferring passive or active immunity to the parasite, C. parvum. A high molecular weight glycoprotein antigen isolated from C. parvum, capable of binding the mAb 3E2, was shown to harbor an epitope critical for trigger... | 01/27/2004 |
| 6680374 | Invaplex from gram negative bacteria, method of purification and methods of use Isolated antibodies to Invaplex; novel compositions comprising immunoglobulins directed to invasin proteins and LPS from gram negative bacteria that selectively bind to Invaplex, and do not bind to the individual components of Invaplex.... | 01/20/2004 |
| 6627740 | Monoclonol antibody which binds to a polypeptide having pre-B cell growth supporting ability The present invention provides a monoclonal antibody which binds to a polypeptide as set forth in SEQ ID NO: 1 as described herein.... | 09/30/2003 |
| 6596689 | Therapeutic method using fucose-containing proteoglycan or acidic glycan A class of proteoglycans containing fucosylated acidic glycans, e.g., as produced by marine sponges and sea urchin embryos, have been found to stimulate selective proliferation of mammalian natural killer (NK) cells and γδT cells. These compounds are us... | 07/22/2003 |
| 6485970 | Immunointeractive antibody The present invention relates generally to immunointeractive molecules and their use inter alia in the detection and/or purification of T-cell antigen binding molecules (TABMs). The ability to determine the presence and levels of particular TABMs provides... | 11/26/2002 |
| 6475775 | PARG, a GTPase activating protein which interacts with PTPL1 The invention describes nucleic acids encoding the PARG protein, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments thereof encoded by such nucleic acids, and antibodies relating thereto. Methods... | 11/05/2002 |
| 6391635 | Monoclonal human natural antibodies Disclosed herein are method for producing hydridoma cell lines producing monoclonal human natural IgM antibodies and hybridoma cells produced by the methods. The antibodies are the monoclonal equivalents of circulating human natural antibodies.... | 05/21/2002 |
| 6316256 | Method for protein transfer Methods for transferring one or more proteins to a cell are disclosed. The protein or proteins to be transferred are in the form of a fusion protein, and contain at least one domain encoding for a protein or peptide having trans signaling and/or adhesion ... | 11/13/2001 |
| 6287568 | Methods relating to immunogenic dextran-protein conjugates This invention includes the conception of T-independent conjugate-vaccines and its application in the induction of antigen specific IgA response. We demonstrated that 1) (1,6)dextran can elicit a markedly enhanced IgA response in T-cell free mice (... | 09/11/2001 |
| 6204366 | Specific binding agents A reshaped human antibody or reshaped human antibody fragment having specificity for human polymorphic epithelial mucin (PEM) is produced by transferring the complementarity determining regions (CDRS) from a murine anti-HMFG hybridoma cell line HMFG1 into... | 03/20/2001 |
| 6165784 | Antibodies for the detection of prion protein as an indication of transmissible spongiform encephalopathies Methods to detect prion or PrP-Sc protein as an indication of transmissible spongiform encephalopathies (TSEs), including preclinical detection of infected live animals, and postmortem detection methods, are described. In one aspect, the invention is dire... | 12/26/2000 |
| 6048537 | Method for preparing an influenza virus, antigens obtained and applications thereof Method for preparing purified influenza antigens from a fluid containing influenza virus, comprising the steps of concentration, purification, fragmentation and, where appropriate, inactivation, characterized in that: A. either the purification step entails se... | 04/11/2000 |
| 6042828 | Humanized antibodies to ganglioside GM2 Chimeric human antibody expression vectors are constructed by inserting the antibody heavy chain variable region-encoding cDNA and antibody light chain variable region-encoding cDNA isolated from hybridomas producing a mouse or rat monoclonal antibody rea... | 03/28/2000 |
| 6015680 | Human lung adenocarcinoma-related monoclonal antibody and immunoassay method which uses the same The monoclonal antibody produced by a hybridoma cell strain TRD-L1, -L2 or -L3 which is obtained by the fusion between mouse myeloma cells and spleen cells of a mouse immunized with a human lung adenocarcinoma cell secretion component reacts in a specific... | 01/18/2000 |
| 6004528 | Methods of cancer diagnosis and therapy targeted against the cancer stemline Improved methods for the diagnosis and treatment of cancer which involve the targeting of slow-growing, relatively mutationally-spared cancer stemline are provided. These methods are an improvement over previous cancer detection and therapeutic methods be... | 12/21/1999 |
| 5939532 | Humanized antibodies to ganglioside GM2 Chimeric human antibody expression vectors are constructed by inserting the antibody heavy chain variable region-encoding cDNA and antibody light chain variable region-encoding cDNA isolated from hybridomas producing a mouse or rat monoclonal antibody rea... | 08/17/1999 |
| 5892000 | Monoclonal antibodies specific for advanced glycosylation endproducts in biological samples The present invention relates to monoclonal antibodies to advanced glycosylation endproducts formed in vivo and cross-reactive with advanced glycosylation endproducts formed in vitro, and to methods of diagnosis and therapy based thereon. More particularl... | 04/06/1999 |
| 5888757 | Cell wall assay Disclosed are methods that can be used to (1) measure the level of polysaccharide in a sample; (2) measure the ability of a compound to degrade a polysaccharide; (3) measure the ability of a compound to modulate polysaccharide synthesis; and (4) identify ... | 03/30/1999 |
| 5876716 | Method of using an antibody to the TN antigen for the inhibition of HIV infection A monoclonal or other antibody to the carbohydrate antigen Tn can be used to inhibit or slow the progression of AIDS or ARC. The antigen can be used in a vaccine, for immunisation.... | 03/02/1999 |
| 5817513 | Anti ganglioside monoclonal antibodies The present invention relates to immunotherapy strategies for the treatment of malignancies. The present immunotherapy strategies have gangliosides as a target. Gangliosides are glycosphingolipids which are present on normal cells and on malignant cells. ... | 10/06/1998 |
| 5786160 | Natural killer cell-specific antigen and antibodies that identify the same A novel natural killer cell-specific molecule, designated as PEN5, consisting essentially of a glycoprotein pair called PEN5 and PEN5ଲ, having apparent molecular weights of 120-150 and 210-245 kdal, respectively. Monoclonal antibodies, includ... | 07/28/1998 |
| 5780032 | Method of using monoclonal antibodies to cytokeratin fragments Provided is a method for reproducible production of cytokeratin antigen/immunogen. Cytokeratins from whole carcinoma cells are purified by preparative SDS-PAGE. Bands corresponding to cytokeratins 8, 18, and 19 are eluted from the gel, and these cytokerat... | 07/14/1998 |
| 5747034 | Methods and materials for the induction of T cell anergy Anti-B7-1 antibodies or other B7-1 ligands may be used to prevent or treat a T-cell-mediated immune system disease in a patient or to induce antigen-specific tolerance. The anti-B7-1 antibodies may be used to cause T cell anergy, treat allograft transplan... | 05/05/1998 |
| 5744318 | Monoclonal antibody for the detection of advanced glycosylation endproducts in biological samples The present invention relates to monoclonal antibodies to advanced glycosylation endproducts formed in vivo and cross-reactive with advanced glycosylation endproducts formed in vitro, and to methods of diagnosis and therapy based thereon. More particularl... | 04/28/1998 |
