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| Number | Title | Issue Date |
| 7767446 | Perfusion bioreactors for culturing cells A bioreactor system comprising a multi-well platform including an array of bioreactor units. The bioreactor system comprises a perfusion unit and a fluid source unit fluidly interconnected by a pumping unit. The perfusion unit comprises a multi-well plate including ... | 08/03/2010 |
| 7655457 | Cell culture vessel and cultured cell It is an object of this invention to provide a cell culture vessel which has a simple and convenient structure, can prevent the injury on the cells at the time of peeling, and accelerates the transportation of nutrients and discharge of waste materials. In order to ... | 02/02/2010 |
| 7374928 | Bio-reactor for the cultivation of micro-organisms and method for the production thereof The invention relates to a bioreactor for cultivating microorganisms, as well as a method for its production. The invention is characterized in that the bioreactor (1) comprises two identically constructed base elements (2,3) that are constructed in tr... | 05/20/2008 |
| 7300789 | Bioreactor forming a rigid vessel The invention provides a bioreactor (10) for the culture of animal, vegetable, microbial of algal cells of their co-cultures, of the type including a body (12) which delimits an internal volume (14) capable of holding a culture liquid (16) and a gas volume (17) abov... | 11/27/2007 |
| 7192767 | Matrix reactor and a method for producing products in said reactor The present invention concerns a matrix reactor for reactions in which low-molecular and high-molecular reactants are involved wherein the reactor space VR contains a matrix and comprises a reaction compartment and a supply compartment, wherein the matrix... | 03/20/2007 |
| 7179643 | Device and a process for expansion of haemopoeitic stem cells for therapeutic use A sterilizable bio-reactor comprising a three-dimensional reactor culture assembly substantially equivalent to a bone marrow micro environment, an inert bio-compatible scaffolding material located on a base of the reactor culture assembly to provide a micro environm... | 02/20/2007 |
| 7022518 | Apparatus and method for co-culturing of cells A co-culture apparatus and method for, among other things, converting a progenitor cell line into a target cell line. The apparatus comprises an exterior receptacle, a removable cartridge that fits into the exterior receptacle, and a closure member to seal the appar... | 04/04/2006 |
| 7015038 | Method and apparatus for preparing and culturing cells A method and an apparatus for preparing and culturing cells, particularly bone marrow stromal cells. The method includes the steps of placing an oxygenator and a scaffold in a container, such as a syringe, withdrawing bone marrow stromal cells with the syringe, even... | 03/21/2006 |
| 6991933 | Cell culture spinner flasks The present invention relates to culturing devices that are compact, utilize small amounts of cell culture media to establish and maintain cell cultures, and produce a large number of cells in a short period of time when compared to other cell culturing devices and ... | 01/31/2006 |
| 6987019 | Device for growing cells A device for growing cells has a container with a bottom; and a plurality of elements extending into an area for growing cells and formed as thin, elongated plates extending along the bottom one after the other at predetermined distances from one another. ... | 01/17/2006 |
| 6794183 | Device for cultivating plant or animal tissue cultures The present invention relates to a device for cultivating plant or animal tissue. The inventive device comprises a fermenter container, a supply device for liquid nutrients and gases, devices for discharging used nutritive liquids and gases and solid carrier plates ... | 09/21/2004 |
| 6790654 | Cell culture harvesting A scraper for scraping live cells from a substrate. The scraper comprises a magnetic core and an elastomeric housing surrounding at least a portion of the magnetic core and defining at least one scraping blade. A method of scraping and a system for scraping are also... | 09/14/2004 |
| 6753178 | Intermittent immersion vessel apparatus and process for plant propagation A plant micropropagation apparatus (100) and process is provided in which a support platform (110) for vessels (12) containing a liquid growth media are periodically pivoted which brings about an intermittent immersion of the plant tissue/growth... | 06/22/2004 |
| 6635441 | Multi-sample fermentor and method of using same A fermentation apparatus is constructed to produce a known and repeatable amount of unpoisoned fermentation product using multiple fermentation vessels. To facilitate further processing compatible with other product processing steps, the fermentation appa... | 10/21/2003 |
| 6599735 | Continuous fermentation system A fermentation assembly comprising: (a) a vessel for culturing living cells; (b) at least two storage flasks in fluid communication with the vessel for supply of liquids and a first transport means for transferring the liquids from the storage flasks to t... | 07/29/2003 |
| 6197597 | Solid phase immunoassay with carriers matching the shape of sample wells The invention concerns a solid-phase determination method and equipment and an adapter for use in these. In the method a sample is allowed to react with a separating reagent bound to the outer surface of a separate solid phase body, whereafter the body is... | 03/06/2001 |
| 6150159 | Cell culture vessel A cell culture vessel formed generally about an elongate axis and being provided with a neck and a removable closure member, and at a distal end thereof an end closure portion; said vessel being adapted for tissue culture growth and formed of a sterilizab... | 11/21/2000 |
| 6127168 | Containers useful for cell cultures and other applications The subject invention provides inexpensive and convenient containers for holding a variety of substances. Although the containers of the subject invention are particularly well adapted for use in cell culture procedures, the versatile nature of these cont... | 10/03/2000 |
| 6107085 | Self contained cell growth system The present application relates generally to a system for the practice of high density cell culture. The system employs the use of two tanks; a cell growth tank having multiple cell growth chambers, is preferably situated within a reservoir tank. A series... | 08/22/2000 |
| 6074871 | Cell-culture reactor having a porous organic polymer membrane A method for making a biocompatible polymer article using a uniform atomic oxygen treatment is disclosed. The substrate may be subsequently optionally grated with a compatibilizing compound. Compatibilizing compounds may include proteins, phosphorylcholin... | 06/13/2000 |
| 6040171 | Apparatus for analyzing biological samples Apparatus for analyzing biological samples includes a unique surface which promotes adhesion, growth and optical analysis of samples. The unique surface is formed at the bottom of each well of a microplate and provides increased surface area with a distri... | 03/21/2000 |
| 6001586 | Compartmentalization method for screening microorganisms A method is provided for screening microorganisms having a selectable characteristic comprising: (a) providing a growth chamber capable of forming a plurality of discrete compartments, said compartments comprising a barrier which inhibits the diffusion of... | 12/14/1999 |
| 5998184 | Basket-type bioreactor Improved hollow fiber bioreactor systems and cell culture methods are described. The improvement includes means which may be a novel basket bioreactor for extending the extracapillary space of a conventional hollow fiber bioreactor.... | 12/07/1999 |
| 5939314 | Distributed pore chemistry in porous organic polymers in tissue culture flasks A method for making a biocompatible polymer article using a uniform atomic oxygen treatment is disclosed. The substrate may be subsequently optionally grated with a compatibilizing compound. Compatibilizing compounds may include proteins, phosphorylcholin... | 08/17/1999 |
| 5935845 | Distributed pore chemistry in porous organic polymers A method for making a biocompatible polymer article using a uniform atomic oxygen treatment is disclosed. The substrate may be subsequently optionally grated with a compatibilizing compound. Compatibilizing compounds may include proteins, phosphorylcholin... | 08/10/1999 |
| 5900374 | Cell culture harvesting device The invention concerns a cell culture harvesting device consisting of a scraper head with a blade and a guide strip, the scraper head and the guide strip being connected with one another only by magnetic attraction. The magnetic attraction is achieved by ... | 05/04/1999 |
| 5879932 | Slow release microorganism dispenser A dispenser and method is provided for slowly releasing microorganisms into a surrounding body of fluid. The surrounding body of fluid may, for example, include a pond, lake, or waste management holding area. A major portion of the dispenser is submerged ... | 03/09/1999 |
| 5869329 | Blood culture vial or bottle having an agitation paddle The present invention describes a blood culture vial and bottle having an agitation paddle that enhances liquid agitation within the container, when the container is rotated on a turntable instrument. In particular, a flexible paddle is inserted into the ... | 02/09/1999 |
| 5866419 | Roller bottle The invention is a roller bottle having a cross-section that is substantially a non-circular closed curve of constant width, wherein said curve is preferably a Reuleaux triangle or a Reuleaux triangle with rounded corners and the use of the roller bottle ... | 02/02/1999 |
| 5861306 | Multi-well bone culture device for use in assessment of bone cell activity The present invention describes a multi-well bone cell culture device for use in the quantitative and/or qualitative assessment of bone cell activity, the device comprising a flat base having a sintered film of calcium phosphate entities on one side and a... | 01/19/1999 |
| 5798261 | Distributed pore chemistry in porous organic polymers A method for making a biocompatible polymer article using a uniform atomic oxygen treatment is disclosed. The substrate may be subsequently optionally grated with a compatibilizing compound. Compatibilizing compounds may include proteins, phosphorylcholin... | 08/25/1998 |
| 5736399 | Medium-penetrating cell culture carrier, a culturing method and a device using this carrier The present invention provides a medium-penetrating culture carrier comprising a plurality of natural or synthetic threads or the woven body thereof, a method for adhering cells onto this carrier to allow them to be proliferated, and a device which is phy... | 04/07/1998 |
| 5731198 | Apparatus for processing bodyfluids Disclosed is an apparatus for processing body fluids which in one embodiment includes a support having ethylenediamine tetraacetic acid, and N-tosyl-lysyl chloromethylketone and/or N-tosyl-phenylalanyl chloromethylketone.... | 03/24/1998 |
| 5702945 | Culture vessel for cell cultures on a carrier The purpose of the present invention is to attain optimal gas exchange, nutrient supply and disposal of metabolic waste products without contamination during high-density cell cultivation of adherent cells. The culture vessel of the present invention prov... | 12/30/1997 |
| 5672505 | Insert for a issue culture vessel An insert of the present invention for a tissue culture bottle with a neck includes a neck adapter with provision for mounting a suspending arm. One end of the suspending arm mounts in the insert and the other end has a holder for a specimen or a pluralit... | 09/30/1997 |
| 5672484 | Microbiological culture bottle, and method of making and using same A container (10) adapted for use in the detection of aerobic microorganisms in a sample includes a non-toxic insert (22) disposed within the container (10) for supporting microorganisms adhered thereto and for increasing microbial exposure to oxygenated g... | 09/30/1997 |
| 5650325 | Apparatus having a rotatable stack of parallel trays with culturing surfaces on opposite sides for liquid/gas exchange An apparatus for providing an enhanced liquid/gas exchange surface such as during call culturing has an enclosed housing, a set of trays arranged in parallel inside the housing with a regular spacing between them, each of the trays being formed with a pla... | 07/22/1997 |
| 5618736 | Method for using synthesized kaolinite as carrier for bioreactor, a composite body composed substantially of synthesized kaolinite as carrier and enzyme carried on synthesized kaolinite, and bioreactor system using such a composite body A process using hydrothermally synthesized porous kaolinite as a carrier for use in a bioreactor. A carrier-biocatalyst composite body for use in a bioreactor, includes the synthesized kaolinite as a carrier and a biocatalyst fixed onto the synthesized ka... | 04/08/1997 |
| 5591627 | Apparatus for arranging cells in culture medium An apparatus for arranging cells in a culture medium includes a substrate having patterns on a surface thereof, the patterns each having different adhesive property to cells, a container containing therein the substrate, cells and liquid culture medium fo... | 01/07/1997 |
| 5527705 | Roller bottle for trans-membrane co-culture of cells and method for its use A roller bottle for trans-membrane co-culture of cells includes an exterior receptacle with a longitudinal axis having a first chamber surrounded by a sidewall. The exterior receptacle has a first neck at one end having an opening therethrough providing f... | 06/18/1996 |
