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| Number | Title | Issue Date |
| 7425441 | Bioreactor for culturing microorganisms A bioreactor for culturing microorganisms which has a reactor vessel, a plurality of gas-introduction tubes and a gas-introduction system for introducing gas into a culture medium in the gas-introduction tubes via injectors, wherein the gas-introduction tubes are co... | 09/16/2008 |
| 7374928 | Bio-reactor for the cultivation of micro-organisms and method for the production thereof The invention relates to a bioreactor for cultivating microorganisms, as well as a method for its production. The invention is characterized in that the bioreactor (1) comprises two identically constructed base elements (2,3) that are constructed in tr... | 05/20/2008 |
| 7329539 | Bioreactor for sewage and wastewater treatment The present invention relates to a bioreactor for sewage and wastewater treatment, which is capable of agitating and supplying oxygen simultaneously. A bioreactor of the present invention, comprises a culture drum in which microorganisms are cultured; a supplier for... | 02/12/2008 |
| 7100905 | Reactor for gas/liquid or gas/liquid/solid reactions A reactor (1) for gas/liquid or gas/liquid/solid reactions having a vertical longitudinal axis and an inlet (2) for a liquid or liquid/solid feed stream in the upper region of the reactor and an inlet (3) for a gaseous stream in the lower region... | 09/05/2006 |
| 7056503 | Enclosures housing cell-coated supports for treating tumors The present invention relates to devices, systems and methods for treating tumors. In particular, the present invention relates to enclosures housing cell-coated supports for promoting regression of tumors, such as cancerous tumors, papillomas, and warts. In preferr... | 06/06/2006 |
| 6709862 | Growing cells in a reservoir formed of a flexible sterile plastic liner A method and apparatus for aseptic biological production of cells and/or microorganisms are provided. The apparatus includes a support housing having an interior chamber, a disposable flexible sterile plastic liner lining the interior chamber and a head plate attach... | 03/23/2004 |
| 6670169 | Bioreactor A bioreactor with a reaction container (1, 1a, 1b, 1c) for a substance (C) to be acted upon with a medium has a pump (5, 5a, 5b, 5c, 5d) for conveying the medium. The pump is designed as an expendable pump or, respectively, parts (53d, 54d, 55d) of the pu... | 12/30/2003 |
| 6492135 | U-shape and/or nozzle u-loop fermentor and method of carrying out a fermentation process A U-shape and/or nozzle-U-loop fermentor has a U-part consisting of an essentially vertical downstream part (2), an essentially vertical upstream part (4), a U-shape bend part (3) which connects the lower ends of the downstream and upstream parts, an inli... | 12/10/2002 |
| 6245555 | Method and apparatus for aseptic growth or processing of biomass A method and apparatus for aseptic biological production or processing of cells, tissues and/or microorganisms is provided. The apparatus includes a support housing having an interior chamber, a disposable liner lining the interior chamber and a head plat... | 06/12/2001 |
| 6174720 | Modified bioreactor Bioreactor apparatus for culture of living matter in a liquid medium includes a plurality of tubes connected at one end to a primary manifold section and at their other end to a secondary manifold section such that a flow of liquid containing the living m... | 01/16/2001 |
| 5985649 | Device and method for removal of gas contaminates through a shallow sparged bioreactor A method and apparatus for removing select gas contaminants is disclosed. The apparatus is a bioreactor having a chamber for containing liquid and a liquid positioned therein, the liquid forming a column having a top and a bottom surface defining a height... | 11/16/1999 |
| 5672507 | Apparatus for the surface culture of nucleated cells and cell culture dependent substances An improved bio-reactor with spiral or coil-shaped filling bodies is disclosed, the improvement comprising use of a gas diffusion tube through which air, oxygen or other gases can be bubbled through the fermentation medium.... | 09/30/1997 |
| 5593890 | Apparatus suitable for conducting gas-liquid reactions An improved apparatus for conducting gas-liquid reactions, comprising a vessel having at least one ascending flow chamber and at least one descending flow chamber. The vessel is especially useful in conducting high cell density fermentation processes, for... | 01/14/1997 |
| 5563068 | Bioreactor A stainless steel column housing is capped with an O-ring sealed cover to form a sealed autoclavable sterile chamber. A pair of stainless steel mesh circular cylindrical concentric inner and outer columns are within the chamber. A bed of porous glass sphe... | 10/08/1996 |
| 5501971 | Method and apparatus for anchorage and suspension cell culture A method and apparatus cultivates anchorage and nonanchorage cell in a reactor. A reactor includes a basket type packed bed and an internal recirculation device. The basket includes a top and bottom portion for allowing medium to flow uniformly through th... | 03/26/1996 |
| 5256380 | Startup openings in a three-phase gaslift loop reactor Reduction of the hysteresis effects in a gaslift loop reactor is effected with a draft tube for solids suspension. The gas or liquid flow rates for generating complete solid suspension are significantly higher than the flow rates necessary for maintaining... | 10/26/1993 |
| 5227136 | Bioslurry reactor for treatment of slurries containing minerals, soils and sludges A reactor vessel for use in treating slurries containing minerals, soils or sludges contaminated with toxic organic substances is disclosed. The vessel includes a tank, having a sealed cover, a mixer arrangement, an air supply arrangement and an exhaust g... | 07/13/1993 |
| 5162051 | Photobioreactor A photobioreactor for the cultivation of photosynthetic microorganisms is disclosed wherein a plurality of baffles are mounted in the photobioreactor tank forming hollow cavities which enable the insertion of light sources through openings in the tank wal... | 11/10/1992 |
| 5081036 | Method and apparatus for cell culture Methods and apparatus are provided for growing both suspension type cells and anchorage dependent cells in airlift bioreactors. A packing means, such as stainless steel wool, is provided in the growth chamber of the bioreactor to increase cell density by ... | 01/14/1992 |
| 4906578 | Aerobic-cultivation tank An aerobic-cultivation tank of vertical type comprises: a closed outer tank structure of cylindrical shape; an internal cooling jacket secured concentrically to the inner wall surface of said tank structure and having a cylindrical space for accommodating... | 03/06/1990 |
| 4782024 | Fermentation process and fermenter A "pressure-cycle" fermentation process and fermenter wherein an oxygen-enriched gas containing at least 30% by volume oxygen is supplied to the fermenter downcomer and the nutrient supply to the fermenter is such as to allow growth of the culture to cont... | 11/01/1988 |
| 4748123 | Continuous fermentation device A continuous fermentation device for receiving a suspension culture of cells includes a fermentation vessel having inlet means to deliver suspension culture medium; baffle means defining, in combination with interior walls of said vessel, a downcomer and ... | 05/31/1988 |
| 4703007 | Separation of volatiles from aqueous solutions by gas stripping Process and apparatus for the recovery of low concentrations of volatile components from a liquid by use of a stripping gas is disclosed. The system is particularly suited for recovery of low concentration volatile metabolites from fermentation broths.... | 10/27/1987 |
| 4668632 | Sparger and apparatus for and method of growing cells A sparger useful for introducing gas into a liquid is composed of one or more gas-permeable members positioned between a gas inlet means and a gas distribution means. A method and apparatus for culturing cells, eukaryotic cells and hybridomas in particula... | 05/26/1987 |
| 4545945 | Process for improving the gas distribution in air-lift loop reactors In a process for improving the gas distribution in air-lift loop reactors, the back-flowing, partially degassed liquid is divided into part streams prior to, during or after entry into the rising part of the loop. In this process, the cross-section of the... | 10/08/1985 |
| 4519959 | Gas-liquid contacting apparatus A gas-liquid contacting apparatus is constituted by an upright vessel, at least one perforated gas distributor for supplying a gaseous medium into a liquid medium within the vessel, a plate-like rotary disintegrator positioned within the vessel and above ... | 05/28/1985 |
| 4482458 | Process and apparatus for the anaerobic treatment of waste water in a filter including granular material Waste water to be treated is introduced into a filter including granular material for supporting the biomass resulting from an anaerobic treatment operation. During such treatment operation biogas is formed, and the waste water being treated and the granu... | 11/13/1984 |
| 4419244 | Method and arrangement for aeration of liquids A method of aerating liquids, particularly for aerobic growing of microorganisms, has the steps of forming a circumferential stream of liquid, forming a longitudinal stream of liquid, and superimposing these streams so as to form a combined closed spiral-... | 12/06/1983 |
| 4357424 | Process for the continuous production of fermentation alcohol A process for the continuous production of fermentation alcohol, by effecting fermentation of a continuous or substantially continuous supply of the liquid substrate by a dense suspension of a suitable micro-organism in a reaction column wherein the suspe... | 11/02/1982 |
| 4327042 | Draft device for a bubble column Disclosed is an improved draft device for a bubble column used in a reaction wherein gas and liquid are mixed such as fermentation. The draft device consists of a plurality of vertical plates coaxially arranged within the bubble column such that each plat... | 04/27/1982 |
| 4311798 | Method of and an arrangement for cultivating cells of animal and human tissues A method of cultivating cells of animal and human tissues includes the steps of introducing the cells into a nutrient solution in which they tend to settle, and maintaining the cells in the solution in a suspended state so as to prevent their settling by ... | 01/19/1982 |
| 4282328 | Apparatus for cultivating aerobic microorganisms and process for cultivation using the same Apparatus for cultivating aerobic microorganisms is provided which comprises cell multiplying compartment and cell ripening compartment. The invention also provides a cultivation process using the same apparatus. The invention improves oxygen transfer rat... | 08/04/1981 |
| 4204042 | Method of gasifying and agitating a fermentation culture The invention relates to a method of and an apparatus for enabling a micro-organism culture to be gasified and agitated so as to accelerate its growth. The culture is contained in a fermenter which comprises two containers C1 and C2 ... | 05/20/1980 |
| 4183787 | Circulation of gas/liquid mixtures A method and apparatus for continuously circulating a mixture comprising a liquid and a gas around a system comprising a riser and a downcomer and a gas disengagement section in which liquid flows downwardly at a velocity which does not exceed 0.2 meters ... | 01/15/1980 |
| 4173516 | Device for cultivating cells of animal and human tissues A method of cultivating cells of animal and human tissues includes the steps of introducing the cells into a nutrient solution in which they tend to settle, and maintaining the cells in the solution in a suspended state so as to prevent their settling by ... | 11/06/1979 |
| 4126517 | Method of converting liquid micro-biological substrate and apparatus for carrying out the method A method of converting liquid micro-biological substrate is disclosed, as is an apparatus for carrying out the method. The liquid substrate is caused to flow along a duct having a cross-sectional area which alternately decreases and increases along the fl... | 11/21/1978 |
| 4048017 | Introduction of nutrient medium into a fermenter A method and apparatus for continuous fermentation wherein a limiting nutrient such as a carbon source is supplied to a culture at sufficient positions and at suitable rates to ensure that another nutrient such as oxygen does not effectively become the li... | 09/13/1977 |
| 3963581 | Air lift fermentors An air lift fermentor comprising in combination a hollow cylindrical body, vertically located and subdivided into three zones by a pair of diaphragms parallel to the axis of said cylindrical body, the central zone of which is destined to fermentation of t... | 06/15/1976 |
| 3957585 | Method for conducting fermentation An apparatus for conducting a fermentation process for the production of single cell protein and the like. The apparatus includes a vessel with a reaction zone and has liquid atomizing means opening thereinto for the injection of atomized liquid into the ... | 05/18/1976 |
| 3954565 | Apparatus for cultivating microorganisms An apparatus for cultivating microorganisms, comprising ejectors adapted to disperse and intermix the culture liquid and aerating agent, the ejectors being rotatable and located in a container for the culture liquid having a diffuser for the directional f... | 05/04/1976 |
