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Class 435/293.2 - Radial or spiral flow bioreactor


Subclass of Class 435 - Chemistry: molecular biology and microbiology
Definition: Apparatus wherein fluid flow in the tubular or plug flow
No. of patents: 41
Last issue date: 04/13/2010


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NumberTitleIssue Date
7695957Bioreactor, in particular for NMR spectroscopy
A description is given of a bioreactor (1), in particular for NMR spectroscopy, comprising a container (7) capable of containing a cell culture, a first inlet line (6) for the inward flow of a culture medium to the inside of the container and a ...
04/13/2010
7572627System of processing mixed-phase streams
Heat transfer in non-turbulent highly viscous mixed-phase flowing streams can be improved by altering flow characteristics using spiral-shaped elements to eliminate boundary phenomena. The spiral-shaped element promotes helical or spiral flow paths to reduce or elim...
08/11/2009
7396673Device for measuring extracellular potential
A sensing element for measuring extracellular potential including a substrate, a well provided in a substrate, a guide section provided on the wall of the well, and a detective electrode formed at a lower surface of the substrate. The guide section is for guiding dr...
07/08/2008
7365582Bootstrapped charge pump driver in a phase-lock loop
A charge pump includes first and second pairs of differential transistors. Each transistor includes control, first, and second terminals. First and second charge pump drivers communicate with the control terminal of one of the first pair of differential transistors ...
04/29/2008
7201787Air cleaner and method of controlling operation thereof
An air cleaner and method of controlling an operation of the same is disclosed. The air cleaner includes a cabinet having an inlet and an outlet; a filter assembly removing dust and smell particles from a room air; a fan; a sensor assembly sensing the composition of...
04/10/2007
7179643Device and a process for expansion of haemopoeitic stem cells for therapeutic use
A sterilizable bio-reactor comprising a three-dimensional reactor culture assembly substantially equivalent to a bone marrow micro environment, an inert bio-compatible scaffolding material located on a base of the reactor culture assembly to provide a micro environm...
02/20/2007
7056725Vegetable alga and microbe photosynthetic reaction system and method for the same
A vegetable alga and microbe photosynthetic reaction system and method for the same is used for vegetable algae and microbe cultivation liquid and algae seeds infused herein to circularly conduct photosynthesis and discharge oxygen; the vegetable alga and microbe ph...
06/06/2006
6979308Bioreactor design and process for engineering tissue from cells
A scaled-up multi-coaxial fiber bioreactor, and variations of this bioreactor. The device is characterized by a hollow housing and an array of from about 20 to about 400 modules of hollow fibers, where each module includes at least three coaxial semipermeable hollow...
12/27/2005
6916630Method and spiral bioreactor for processing feedstocks
A potential energy field flow bioreactor for processing a reagent includes a flow pathway, preferably in the form of a spiral, through which pathway is flowed reactant particles and at least one initial reagent adapted to react therewith. The reaction generates an e...
07/12/2005
6905874Simultaneous stimulation and concentration of cells
The present invention relates generally to methods for stimulating cells, and more particularly, to a novel method to concentrate and stimulate cells that maximizes stimulation and/or proliferation of such cells. In the various embodiments, cells are stimulated and ...
06/14/2005
6627435Perfusion incubator
A perfusion incubator having a fluid conditioning unit (12), a well assembly (7) and a well assembly heating unit (14), a peristaltic pump (4) and a fluid collection unit (11). The well assembly has a number of wells (20, 21) each having a transparent lid...
09/30/2003
6620614Solid-state fermenter and method for solid-state fermentation
The invention concerns a solid state fermenter in particular for large volumes as well as a procedure for solid state fermentation. The task of the present invention was the development of a solid state fermenter for large volumes and of a procedure for solid ...
09/16/2003
6589780Bio-reactor for enhancing the biomass yield of plant organs
A bio-reactor for enhancing the biomass yield using a closed sterile vessel having a medium, said reactor comprising a central shaft, a support matrix oriented horizontally and dividing the vessel into an upper and a lower chamber, a means for stirring se...
07/08/2003
6562616Methods and devices for cell culturing and organ assist systems
The invention relates to new flow-through cell culturing devices that include plates arranged in parallel and spaced to control the flow patterns and velocity of liquid medium flowing between the plates. The devices can also include gas-permeable, liquid ...
05/13/2003
6319706Process and apparatus for remedying polluted media
A process to remedy a polluted medium includes contacting a first medium containing a pollutant with a second medium containing a microorganism which is capable of decomposing the pollutant. A membrane permeable to the pollutant and impermeable to the mic...
11/20/2001
6238912Method and apparatus for contacting gas and liquid
A method and apparatus for contacting a gas and liquid. An elongated cylindrical reactor has an inlet region of reduced cross-sectional area at a first end. At least some of the gas or liquid is introduced into the inlet region in a direction tangential t...
05/29/2001
6180394Method of carrying out a treatment in the presence of a centrifugal force and an apparatus therefor
The invention relates to a method and an apparatus for carrying out a treatment in the presence of centrifugal force. The treatment may be a physical or a chemical treatment. For this purpose the first and second phase are brought into contact with each o...
01/30/2001
6174720Modified bioreactor
Bioreactor apparatus for culture of living matter in a liquid medium includes a plurality of tubes connected at one end to a primary manifold section and at their other end to a secondary manifold section such that a flow of liquid containing the living m...
01/16/2001
6048721Bioreactor for mammalian cell growth and maintenance
A bioreactor for the ex vivo maintenance and growth of mammalian cells includes a disposable, self contained cell cassette, a system manager, an incubator unit matable with a plurality of the cassettes and a processor unit. The cell cassette includes a su...
04/11/2000
5888807Devices for maintaining and growing human stem and/or hematopoietics cells
Methods, compositions and devices are provided for the growth of human stem and/or hematopoietic cells in culture. Bioreactors are provided in which diverse cell types are simultaneously-cultured in the presence of appropriate levels of nutrients and grow...
03/30/1999
5846817Bioreactor, in particular for microgravity
A bioreactor, in particular for a microgravity, comprising at least one cell culture chamber, an oxygen supply and an agitator for a cell culture. In particular, the chamber includes two housing elements (1, 2) having a first (1', 9) and a second (2', 9')...
12/08/1998
5763266Methods, compositions and devices for maintaining and growing human stem and/or hematopoietics cells
Methods, compositions and devices are provided for the growth of human stem and/or hematopoietic cells in culture. Bioreactors are provided in which diverse cell types are simultaneously-cultured in the presence of appropriate levels of nutrients and grow...
06/09/1998
5705390Bioreactor
A radial flow bioreactor comprising a reaction vessel having an inlet and an outlet respectively for adding and withdrawing a culture medium and at least one cell basket within the reaction vessel for accommodating a plurality of cell carriers and having ...
01/06/1998
5688687Bioreactor for mammalian cell growth and maintenance
A bioreactor for the ex vivo maintenance and growth of mammalian cells includes a disposable, self contained cell cassette, a system manager, an incubator unit matable with a plurality of the cassettes and a processor unit. The cell cassette includes a su...
11/18/1997
5556765Reactor using tubular spiroids for gas/liquid propulsion
A reactor includes a reaction vessel that defines a reaction chamber. Completely or partially within the reaction chamber is at least one spiroid. The spiroid is operably associated with the reaction vessel so that rotation of the reaction vessel causes t...
09/17/1996
5501971Method and apparatus for anchorage and suspension cell culture
A method and apparatus cultivates anchorage and nonanchorage cell in a reactor. A reactor includes a basket type packed bed and an internal recirculation device. The basket includes a top and bottom portion for allowing medium to flow uniformly through th...
03/26/1996
5459069Device for maintaining and growing human stem and/or hematopoietics cells
Devices are provided for the growth of human stem and/or hematopoietic cells in culture. Bioreactors are provided in which diverse cell types are simultaneously-cultured in the presence of appropriate levels of nutrients and growth factors substantially c...
10/17/1995
5166071Separation of elements defining a fluid flow path through the use of particles
An element having a spacer for uniformly separating adjacent surfaces of elements defining a fluid flow path therebetween. The spacer comprises particles adhered to at least one of the surfaces. The invention is particularly useful in elements and apparat...
11/24/1992
5057428Bioreactor
A bioreactor comprises a cylindrical tank, a cylindrical mesh member arranged inside the tank concentrically therewith so that the mesh member separates an inner space of the tank into an outside space defined between an inner wall of the tank and the mes...
10/15/1991
4895806Device for liquid chromatography or immobilized enzyme reaction
A device for separating molecular components from liquids. A multi-layer microporous membrane assembly is located within the housing (1) with edges of each membrane within the assembly lying adjacent to a barrier. Means (5,6) are provided for substantiall...
01/23/1990
4861725Mammalian cell culture apparatus
A cell culture apparatus includes a sealed container in which a plurality of porous tubular members are positioned. The tubular members are arranged concentrically. A removable sampling bar is inserted into the innermost tubular member in the container so...
08/29/1989
4833083Packed bed bioreactor
A bioreactor for anchorage or nonanchorage dependent cells or for immobilized enzymes that is capable of achieving high cell densities or concentrations of reaction products is disclosed. The bioreactor is capable of being easily scaled up. The bioreactor...
05/23/1989
4789634Carrier for the cultivation of human and/or animal cells in a fermenter
A carrier for the cultivation of animal and/or human cells in a fermenter, comprises a polymer base body of a solid formed into a pressure-resistant matrix, with a capillary system for carrying the liquid cell culture medium therethrough, with no cell gro...
12/06/1988
4689302Spiral designed reactor
A flow reactor for reacting a feedstock with a proteinaceous preparation immobilized on and within the pores of a support medium while traversing a spiral path between adjacent turns of said spiral. A support medium has a spacing means placed on one surfa...
08/25/1987
4546083Method and device for cell culture growth
A cell culture device is disclosed for the cultivation of animal, plant, microbiological or artificial cells. The device involves a three-dimensional arrangement of fibers within a housing arranged to provide maximum exposed fiber surface flow channel dia...
10/08/1985
4292409Flow reactor for enzymatic reactions in which the enzyme is immobilized on a solid matrix having a planar surface
A novel reactor for enzymatic reactions comprises a flow cell which is constituted by two semi-blocks having a planar surface. The enzyme is immobilized on one of the semi-blocks while a thin channel is provided on the face of the other semi-block. The tw...
09/29/1981
4242461Radial reactor for enzyme-catalyzed reactions
For effecting enzymic reaction, a reactor is disclosed, in which the flow of the solution to be treated through the catalytic bed material takes place radially. It is preferred to have the catalytic bed in the form of coils of enzyme-occluding fibers. The...
12/30/1980
4033825Cell culture system
A cell culture system includes an incubator chamber, and a carriage that is removable from the incubator chamber and that carries a plurality of cell culture chambers. Also mounted on the carriage are a manifold structure having supply and return conduits...
07/05/1977
3948732Cell culture assembly
A replaceable, sterilizable, cell growth assembly comprising a chamber structure of gas permeable, liquid impermeable material having an inner surface to which cells are attachable. The chamber is of tubing configuration and is disposed in a plurality of ...
04/06/1976
3941661Roller culture bottle insert
A plastic spiral insert for use in existing roller culture bottles effective to increase the total surface area available for cell culture. The insert consists of a continuous coil of plastic sheet material that may be thermally set so as to retain its sp...
03/02/1976
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