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| Number | Title | Issue Date |
| 8232096 | Bioreactor for selectively controlling the molecular diffusion between fluids A diffusion controlling bioreactor that selectively controls the molecular diffusion between fluids through at least one microchannel in fluid communication with a reaction reservoir. Length and cross-sectional area of the microchannel may be selected to obtain a pr... | 07/31/2012 |
| 8192981 | Bioreactor system In one aspect the invention provides a bioreactor system for the production of tissue prostheses. The system includes a bioreactor, a culture medium reservoir coupled to the bioreactor by a first conduit and a second conduit, a pump operable to pump fluid into and d... | 06/05/2012 |
| 7939315 | Continuous culture apparatus with mobile vessel, allowing selection of filter cell variants Method and device that increases the rate of reproduction (through increased speed of reproduction and/or increased reproductive yield) of living cells in suspension or of any culturable organisms through the process of natural selection, said device comprising: a) ... | 05/10/2011 |
| 7906323 | Automated bioculture and bioculture experiments system The present invention provides a feedback controlled bioculture platform for use as a precision cell biology research tool and for clinical cell growth and maintenance applications. The system provides individual closed-loop flowpath cartridges, with integrated, ase... | 03/15/2011 |
| 7858366 | Integrated airborne substance collection and detection system An integrated collection and detection system is configured to monitor the ambient air for specific particles, such as toxins and pathogens. An air collector captures airborne particles and outputs a fluid sample including the captured particles in a fluid solution.... | 12/28/2010 |
| 7855070 | Centimeter-scale, integrated diagnostics incubator for biological culturing Disclosed are portable, disposable, centimeter-scale, integrated diagnostics incubators for use in biological culturing. An exemplary incubator comprises an optically accessible enclosure having a plurality of fluidic ports. A heating element is disposed within the ... | 12/21/2010 |
| 7824906 | Anaerobic reactor and corresponding method for digesting organic material The present invention is an anaerobic reactor and preferably a vertically oriented plug flow anaerobic reactor for producing methane from various organic materials. The organic materials preferably have a high organic content. The reactor includes cutting members fo... | 11/02/2010 |
| 7820430 | Micro device for cell culture A micro device for cell culture is disclosed, which cooperates with a fluid and includes: a top plate having an inlet port; a orifice plate having a plurality of orifices; a culture plate having a plurality of culture wells and a plurality of injection ports; and a ... | 10/26/2010 |
| 7704734 | Device for raising or cultivating cells in a container-like receptacle A device for raising or cultivating cells in a container-like receptacle, comprises a base and at least one lid. The at least one lid is connected to the receptacle in a pressure-tight manner. The receptacle or the lid is provided with at least one connector drillin... | 04/27/2010 |
| 7659108 | Fermenter comprising an agitator A plug-flow operated, horizontal fermenter for anaerobic fermentation of biogenic waste includes a fermenter tank having an inlet and an outlet that is configured to be filled with a biomass material. The fermenter also includes an agitator having a shaft passing th... | 02/09/2010 |
| 7582474 | Process reactor with layered packed bed Packed bed reactors that have a series of alternating layers of packing. A first packing layer has open body packing elements randomly packed in a layer up to about 10 packing elements deep; and a second packing layer has porous support elements of hydrophobic foam.... | 09/01/2009 |
| 7514256 | Bioreactor for selectively controlling the molecular diffusion between fluids A diffusion controlling bioreactor that selectively controls the molecular diffusion between fluids through a microchannel in fluid communication with a reaction reservoir. The length and cross-sectional area are selected to obtain a predetermined rate of molecular ... | 04/07/2009 |
| 7435579 | Biosensor and related method A microscale biosensor for use in the detection of target biological substances includes a detection chamber disposed on the substrate and defining a volume between 1 pico-liter and 1 micro-liter. The detection chamber is adapted to confine a composition containing ... | 10/14/2008 |
| 7416884 | Bioreactor and methods for tissue growth and conditioning A bioreactor and methods of using same for making tissue constructs and for conditioning tissue-engineered constructs and harvested tissues such as cryopreserved tissues. The bioreactor allows for static and dynamic culture/conditioning. The bioreactor is dual chamb... | 08/26/2008 |
| 7399629 | Cell/tissue culture apparatus The invention provides a cell/tissue culture apparatus capable of applying an optional physical stimulation to a material to be cultivated serving as a cell or tissue to be cultivated and of protecting the material to be cultivated from contamination of various bact... | 07/15/2008 |
| 7396673 | Device for measuring extracellular potential A sensing element for measuring extracellular potential including a substrate, a well provided in a substrate, a guide section provided on the wall of the well, and a detective electrode formed at a lower surface of the substrate. The guide section is for guiding dr... | 07/08/2008 |
| 7358082 | Device and method for culturing cells An object of the present invention is to construct a culture device optimized for culturing animal cells. The present invention provides a device for culturing cells which comprises at least one water-containing polymer gel film for adhering animal cells onto at lea... | 04/15/2008 |
| 7358078 | Auto microfluidic hybridization chip platform An auto microfluidic hybridization chip platform is disclosed to provide a hybrid reaction test system with the features of fast reactions, automatic operations, and a convenient platform. The platform includes a flow control system with a platform base, a microflui... | 04/15/2008 |
| 7326564 | Flow system for medical device evaluation and production In some embodiments, a flow system includes a medical device mount, fluid and a conduit containing the fluid and medical device mount. The conduit is mounted on an assembly that moves the conduit along with the medical device mount to induce relative motion of the f... | 02/05/2008 |
| 7294503 | Microfabricated crossflow devices and methods A microfluidic device for analyzing and/or sorting biological materials (e.g., molecules such as polynucleotides and polypeptides, including proteins and enzymes; viruses and cells) and methods for its use are provided. The device and methods of the invention are us... | 11/13/2007 |
| 7288405 | Devices and methods for pharmacokinetic-based cell culture system Devices, in vitro cell cultures, systems, and methods are provided for microscale cell culture analogous (CCA) device. ... | 10/30/2007 |
| 7270996 | Automated bioculture and bioculture experiments system The present invention provides a feedback controlled bioculture platform for use as a precision cell biology research tool and for clinical cell growth and maintenance applications. The system provides individual closed-loop flowpath cartridges, with integrated, ase... | 09/18/2007 |
| 7264962 | Enzymatic cascade bioreactor Disclosed is an apparatus and method for continuously converting sucrose to β-D-glucose. The method comprises a three stage enzymatic reactor in which an aqueous solution of sucrose is first converted into a solution of fructose and α-D-glucose by passing it throu... | 09/04/2007 |
| 7256035 | System for thermocycling of fluids in cartridges System for thermocycling of fluids in cartridges comprising a thermocycling unit in thermal contact with a first substantially planar and heat conducting wall of a cartridge, a light source for transmitting light into the interior of said cartridge through a second ... | 08/14/2007 |
| 7247470 | Method and apparatus for measuring nitric oxide production and oxygen consumption in cultures of adherent cells An apparatus and method for measuring nitric oxide production and oxygen consumption in cultures of adherent cells continuously and without destroying the cells. The method involves flowing growth media through a tube having adherent cells are adhered to the inner s... | 07/24/2007 |
| 7235400 | Laminated microarray interface device A device for forming a low volume reaction chamber on a substrate such as a microarray slide and its method of use is disclosed. The reaction chamber forming device has an adhesive laminate design that permits it to be manufactured as a disposable device. A preferre... | 06/26/2007 |
| 7179637 | Apparatus and method for using intestinal segments or their substitutes in high-throughput analysis of compound absorption An apparatus for high-throughput analysis of compound absorption in a controlled environment that closely resembles in-vivo conditions. The apparatus includes at least one tissue-receiving enclosure that is capable of interfacing (e.g., via transfer of fluids, elect... | 02/20/2007 |
| 7160348 | Mist elimination hood A mist elimination device in the form of a hood for the removal of moisture from a gas stream treated by a WESP includes a series of gutters on the outer surface of the hood to trap liquid droplets and direct the moisture to channels to drain to the lower region of ... | 01/09/2007 |
| 7144726 | Apparatus for culturing cell/tissue A cell/tissue culture apparatus can give a physical stimulation necessary for proliferation and growth to a cultured object which is a cell or tissue to be cultured. The cell/tissue culture apparatus has a chamber (a culture chamber 4) which accommodates a cu... | 12/05/2006 |
| 7091035 | Cell culturing and storage systems, devices and methods Featured is a long-term cell culture system being configured and arranged so as to be capable of monitoring the dynamic processes that occur during proliferation and differentiation of stem cells such as central nervous system (CNS) stem cells/embryonic stem cells. ... | 08/15/2006 |
| 7056725 | Vegetable alga and microbe photosynthetic reaction system and method for the same A vegetable alga and microbe photosynthetic reaction system and method for the same is used for vegetable algae and microbe cultivation liquid and algae seeds infused herein to circularly conduct photosynthesis and discharge oxygen; the vegetable alga and microbe ph... | 06/06/2006 |
| 7054766 | Fluid properties evaluation Fluid flow properties often dictate the performance of processing operations. The present invention relates to a system for evaluating properties of a fluid flowing in a pipe. A test cell (20) which includes two parallel surfaces (5, 6) which are posit... | 05/30/2006 |
| 7029838 | Prevascularized contructs for implantation to provide blood perfusion This application discloses methods and materials for preparing functional microvascular beds in the laboratory. These prevascularized constructs can be used to vascularize engineered tissue constructs or to revascularize damaged or diseased tissues or organs followi... | 04/18/2006 |
| 7018824 | Mannosyl transfer with regeneration of GDP-mannose A one-pot glycosylation reaction is disclosed in which a mannosyl (Man) group is enzymatically transferred to an acceptor molecule. The starting glycoside is a mannosyl 1-phosphate that is enzymatically converted to its GDP derivative via UTP and a pyrophorylase. Th... | 03/28/2006 |
| 6991628 | Device and method for creating a vascular graft in vitro Methods and apparatus are provided for forming a vascular graft in vitro by axially distending a blood vessel to induce growth. The apparatus comprises a chamber containing a tissue culture medium, an inlet cannula, an outlet cannula, and a means for moving the inle... | 01/31/2006 |
| 6946287 | Device for providing a hybridization chamber, and process unit and system for hybridizing nucleic acid samples, proteins, and tissue sections A device (1) is disclosed for providing a hybridization chamber (2), for hybridizing nucleic acid samples, proteins, or tissue sections on a slide (3), which is implemented so that it is movable in relation to this slide (3) and includes ... | 09/20/2005 |
| 6939392 | System and method for thermal management A system for the management of thermal transfer in a gas turbine engine includes a heat generating sub-system in operable communication with the engine, a fuel source to supply a fuel, a fuel stabilization unit to receive the fuel from the fuel source and to provide... | 09/06/2005 |
| 6936463 | Method and device for making different thickness of biofilms A method and device for making different thickness of biofilms is disclosed. It comprises: (a) a pair of pentagonal dish including a dish bottom and a dish cover; (b) an internal thickness module having a number of protrusions of different heights or of the same hei... | 08/30/2005 |
| 6919440 | Mannosyl transfer with regeneration of GDP-mannose A one-pot glycosylation reaction is disclosed in which a mannosyl (Man) group is enzymatically transferred to an acceptor molecule. The starting glycoside is a mannosyl 1-phosphate that is enzymatically converted to its GDP derivative via UTP and a pyrophorylase. Th... | 07/19/2005 |
| 6911148 | Adsorptive membrane device for treating particle-laden liquid feeds There is disclosed a device for the simultaneous separation of particles and target substances from liquid feeds by adsorption membranes having particle-passing apertures therein. ... | 06/28/2005 |
