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| Number | Title | Issue Date |
| 7670833 | High throughput analysis for molecular fractions This invention presents the high throughput (HT) analysis technology for molecular fractions employing micro-array format. Molecules are fractionated according to the properties of molecules and are assigned primary designated orders while their tissue origins are a... | 03/02/2010 |
| 7666664 | Instrument for heating and cooling An instrument and method is provided that conveniently allows rapid amplification of nucleic acids. The instrument comprises in the following order at least one substantially flat temperature sensor element; a heat conducting substrate and a heater layer, whereby th... | 02/23/2010 |
| 7662613 | Disease diagnosis apparatus and method using photocurrent of amorphous silicon Provided is a disease diagnosis apparatus and method for detecting a specific disease. The disease diagnosis chip, includes: a light sensing layer; a probe molecule fixed on the light sensing layer; and an electrode connected to the light sensing layer to detect an ... | 02/16/2010 |
| 7662612 | Chemical sensor device A sensor device is provided for performing rapid and high-sensitivity detection. The sensor device comprising at least one support for immobilizing a subject to be detected and a cell for containing a solution in which a reaction product generated from the subject t... | 02/16/2010 |
| 7659107 | Rapid test for glycated albumin A rapid immunochromatographic assay system is provided for measuring the amount of glycated albumin in a blood sample relative to the total level of albumin in the sample. The assay system is comprised of a disposable cassette that contains the test strips and testi... | 02/09/2010 |
| 7642085 | Protein arrays The invention provides proteins attached to solid supports, and methods of preparing such solid support-bound proteins are provided. The proteins are attached to solid supports by means of an unnatural amino acid incorporated into the protein, which unnatural amino ... | 01/05/2010 |
| 7642087 | Chromatography kit, examination container, and method for manufacturing the same An chromatography kit is described, a representative one of which includes: an examination container one end of which has an inlet for receiving a sample, and an chromatography examination strip used by inserting from the inlet into the examination container wherein... | 01/05/2010 |
| 7642086 | Labeled probe bound object, method for producing the same and method for using the same A method for labeling an object, which is effective when multiple types of labels are given as necessary even to a very small object such as a fine particulate substrate for use in fixation of biological substances such as probe molecules or nucleic acid primers tha... | 01/05/2010 |
| 7629164 | Methods for genotyping polymorphisms in humans The invention provides nucleic acid sequences that are complementary, in one embodiment, to a collection of human single nucleotide polymorphisms. The invention provides the sequences in such a way as to make them available for a variety of analyses including genoty... | 12/08/2009 |
| 7622295 | Molecular microarrays and helical peptides Methods for fabricating dense arrays of polymeric molecules in a highly multiplexed manner are provided using semiconductor-processing-derived lithographic methods. Advantageously, the methods are adaptable to the synthesis of a variety of polymeric compounds. For e... | 11/24/2009 |
| 7618811 | Thermal cycling device A multi-layer device suitable for thermal cycling is set forth. The device is particularly suitable for performing a polymerase chain reaction (PCR). One embodiment includes a first layer (18), a second layer (20) adjacent to the first layer, and a thi... | 11/17/2009 |
| 7618812 | Device and process unit for providing a hybridization chamber A device provides a hybridization chamber for hybridizing nucleic acid samples, proteins or tissue sections on a slide, and is an essentially rectangular body movable opposite the slide. The device includes a surface, lines for supplying and/or removing media, a spe... | 11/17/2009 |
| 7615370 | System having device for preventing air bubbles in a hybridization chamber and corresponding method The present invention relates to a system (1) having hybridization chambers (5) for hybridizing nucleic acid samples, proteins, or tissue sections immobilized on slides (27), each hybridization chamber (5) being defined as an essentially ... | 11/10/2009 |
| 7611888 | Rotaxane compound, rotaxane-bonded solid substrate, and biochip using the same The present disclosure provides a rotaxane compound that can be used to separate molecules within a linkage layer formed on a solid substrate of a biochip by a predetermined distance. The compound is represented by Formula 1, in which a compound of Formula 3 vertica... | 11/03/2009 |
| 7611889 | Method for noncovalently immobilizing a biomolecule on a solid substrate and microarray produced according to the method Provided is a method for noncovalently immobilizing a biomolecule on a solid substrate, including: providing a solid substrate having a first functional group attached thereto, the first functional group having a hydrogen bond donating ability; and reacting a mixtur... | 11/03/2009 |
| 7604982 | High-throughput screening method for intergrin antagonist and new peptide screened therefrom The present invention relates to the screening method of antagonistic material of integrin using the protein chip and useful peptides screened thereby. The protein chip used in the present invention is unique substrate coated with new material, calixarene derivative... | 10/20/2009 |
| 7604983 | Apparatus and methods for parallel processing of micro-volume liquid reactions Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array o... | 10/20/2009 |
| 7604981 | Excitable target marker detection A variety of types of molecules are detected and/or analyzed using an integrated micro-circuit arrangement. According to an example embodiment of the present invention, a micro-circuit arrangement detects excitable target markers in response to an excitation source.... | 10/20/2009 |
| 7601532 | Microarray for predicting the prognosis of neuroblastoma and method for predicting the prognosis of neuroblastoma A microarray for predicting the prognosis of neuroblastoma, wherein the microarray has 25 to 45 probes related to good prognosis, which are hybridized to a gene transcript whose expression is increased in a good prognosis patient with neuroblastoma and are selected ... | 10/13/2009 |
| 7585662 | Container for an analysis chip A receptacle is provided for accommodating an analysis chip, which receptacle has openings in a housing having access to the analysis chip, which openings are protected from external influences by a movable protector, and for carrying out an analysis, a mechanism fo... | 09/08/2009 |
| 7585664 | Integrated circuit optical detector for biological detection This invention provides an integrated circuit (IC) optical detector. The IC optical detector comprises a substrate and an IC. The substrate comprises a plurality of test sites defined thereon. The test sites comprise a surface suitably treated for coating of at leas... | 09/08/2009 |
| 7585663 | Thermal device, system, and method, for fluid processing device A device, system, and method are provided for thermally treating a fluid processing device. According to various embodiments, a system is provided that can include a thermal device and a fluid processing device holder. The thermal device can include a first block ha... | 09/08/2009 |
| 7579184 | Methods to increase dynamic range and improve quantitative analysis in rapid biosensors Conductimetric assay devices that have both low end and high end sensitivity are described. The geometric shape and/or arrangement of the capture zones make it possible for the assay devices to have both low end and high end sensitivity. Also described is a conducti... | 08/25/2009 |
| 7575915 | Biosensor A biosensor is provided with a development layer for developing an inspection target solution, that has a reagent immobilization part where an antibody for a measurement target in the inspection target solution is immobilized and a reagent holding part which marks i... | 08/18/2009 |
| 7572624 | DNA chip comprising a microarray made of an microelectrode system A DNA chip includes a carrier and a microarray of spots containing immobilised catcher molecules which are arranged on the carrier. Each spot contains a microelectrode system for the impedance spectroscopic detection of binding events occurring between the catcher m... | 08/11/2009 |
| 7572625 | Medical devices coated with drug carrier macromolecules A medical device coated with carrier macromolecules, wherein the carrier macromolecules are conjugated with a therapeutic agent. The carrier macromolecules may be antibodies which bind the therapeutic agent at the antigen binding site or by covalent bonding. The car... | 08/11/2009 |
| 7569381 | Biochemical reaction cassette with improved liquid filling performance A biochemical reaction cassette comprises a housing member, a reaction chamber arranged in the housing member and having a bottom section and a ceiling facing the bottom section, an injection port arranged at the ceiling of the reaction chamber, a discharge port arr... | 08/04/2009 |
| 7560270 | Biochip cartridge and biochip reader A biochip cartridge has a vessel and a lid portion having a plurality of microlenses. A biochip having a plurality of sites is provided in the vessel. The plurality of sites are to be disposed at the same pitches as the microlenses. Excitation light is applied to ea... | 07/14/2009 |
| 7550288 | Reaction method with use of biochemical analysis unit A biochemical analysis unit has a flow-through area in which plural spot areas are arranged, and probes are spotted onto the spot areas. The biochemical analysis unit is set into a chamber of a reaction vessel. A reaction solution containing a target is supplied thr... | 06/23/2009 |
| 7550289 | Method of fabricating an entegral device of a biochip intergrated with micro thermo-electric elements and the apparatus thereof A method of fabricating an integral device of a biochip integrated with micro thermo-electric elements and the apparatus thereof is disclosed. The micro thermo-electric biochip includes a micro thermo-electric temperature control unit and a biochip unit, and both of... | 06/23/2009 |
| 7544504 | Diagnostic methods The present invention relates to novel methods for the diagnosis of Helicobacter pylori infection. Specifically, the present invention relates to novel non-invasive methods for the detection of the presence or absence of a Helicobacter pylori antigen o... | 06/09/2009 |
| 7544505 | Hybridization chamber agitation device using pump and valves Provided is an agitation device used to agitate a solution in a hybridization chamber, the agitation device including: the hybridization chamber; first and second air channels connected to ends of the hybridization chamber; a first valve disposed in the first air ch... | 06/09/2009 |
| 7541176 | Fluorescence biosensor A fluorescence detector includes a light source being positioned so that in use, radiation emitted therefrom falls on one or more fluorescing species, and a photodetector being switchably connectable between a charge integrator device and a charge disposal device. T... | 06/02/2009 |
| 7524672 | Microfluidic microarray systems and methods thereof Disclosed are systems that include a manifold in fluid communication with a microfluidic chip having a microarray, an illuminator, and a detector in optical communication with the microarray. Methods for using these systems for biological detection are also disclose... | 04/28/2009 |
| 7510865 | Sensing switch and detecting method using the same Provided are a sensing switch and a sensing method using the same. The sensing switch includes: a substrate; a supporter on the substrate; a sensing plate that is connected to a side of the supporter and is in parallel with the substrate by a predetermined distance;... | 03/31/2009 |
| 7507575 | Multiplex fluorescence detection device having removable optical modules Techniques are described for the detection of multiple target species in real-time PCR (polymerase chain reaction). For example, a system comprises a data acquisition device and a detection device coupled to the data acquisition device. The detection device includes... | 03/24/2009 |
| 7507576 | Method of manufacturing probe carrier A flat plate-shaped probe carrier for carrying probes such as single stranded DNAs, proteins, etc., which are reactive specifically with target substances comprises a plurality of ring bodies arranged substantially in parallel and the external space among the ring b... | 03/24/2009 |
| 7482153 | Nucleic acid detection cassette and nucleic acid detection device A nucleic acid detection cassette includes a cassette body, a nucleic acid detection region disposed in the cassette body, a first channel disposed in the cassette body, a second channel disposed in the cassette body. The nucleic acid detection region, in which a nu... | 01/27/2009 |
| 7476533 | Diagnostic devices for use in the assaying of biological fluids Diagnostic in-vitro devices for use in the assaying of biological fluids are provided which include cover plates or backing strips which exhibit hydrophilic properties to assist in transport of the biological fluid or retention of same within the device. Exemplary d... | 01/13/2009 |
| 7473551 | Nano-mechanic microsensors and methods for detecting target analytes The present invention relates generally to methods and compositions for analyzing test samples containing target analytes including proteins and nucleic acids. The invention uses a surface acoustic wave sensor in combination with a hydrogel to obtain an ultra sensit... | 01/06/2009 |