...that after Walter Hunt patented the safety pin in 1849, he sold the rights to it for $400?
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| Number | Title | Issue Date |
| 8021869 | Method of cell storage in a delivery system comprising a fibrous matrix Cell storage and delivery systems and methods for storing and delivering viable cells to a mammal are disclosed. The cell storage and delivery systems include a biodegradable and/or bioabsorbable fibrous matrix physically associated with viable cells to contain and ... | 09/20/2011 |
| 7648832 | Methods for lyophilizing competent cells This invention relates to a method for producing cells which are competent for transformation and which may be stably stored for extended periods of time at various temperatures. The method involves growing cells in a growth conducive medium, rendering said cells co... | 01/19/2010 |
| 7358284 | Particulate acellular tissue matrix A method of processing an acellular tissue matrix to give a particulate acellular tissue matrix includes: cutting sheets of dry acellular tissue matrix into strips; cryofracturing the dry acellular tissue matrix strips at cryogenic temperatures; separating the resul... | 04/15/2008 |
| 7335552 | Electrode for thin film capacitor devices A method of forming a conductor on a substrate including steps of depositing tantalum on a glass layer of the substrate; oxidizing the tantalum; and depositing a noble metal on the oxidized tantalum to form the conductor. The method can be used to form a ferroelectr... | 02/26/2008 |
| 7323297 | Stabilized polynucleotide complexes and methods The invention comprises stabilized polynucleotide complexes that have a cryoprotectant and are lyophilized. Cryoprotectant compounds comprise carbohydrates or sugars, preferably lactose and sucrose, but also glucose, maltodextrins, mannitol, sorbitol, trehalose, and... | 01/29/2008 |
| RE40023 | Dietary and pharmaceutical compositions containing lyophilized lactic bacteria, their preparation and use A pharmaceutical composition containing several different bacteria including Streptococcus thermophilus, Lactobacilli and Bifidobacteria is disclosed. The bacteria are present in the composition at a total concentration of 1×1011 to 1×1013 pe... | 01/22/2008 |
| 7316896 | Egg freezing and storing tool and method An egg freezing and storing instrument has an egg freezing and storing tube made of a liquid nitrogen-resistant material; and a metal cylindrical protection member for protecting the tube. The tube has a body part; and an egg-storing small-diameter part having an in... | 01/08/2008 |
| 7270990 | Virus production An improved process for recovery of virus from allantoic fluid of virus-infected chick embryos. Virus associated with granular and fibrous debris in the allantoic fluid can be disassociated from the debris and recovered, thereby increasing viral yield. Dissociation ... | 09/18/2007 |
| 7253002 | Fluid storage and dispensing vessels having colorimetrically verifiable leak-tightness, and method of making same A chemical storage and dispensing vessel having associated therewith a colorimetric member that is effective to change color in exposure to leakage of a gas contained in the vessel. The colorimetric member may be constituted by a film, e.g., of a shrink-wrap charact... | 08/07/2007 |
| 7244595 | Method of maintaining or improving a nitrile hydratase activity The object of this invention is to provide a method which not only maintains the nitrile hydratase activity of a nitrile hydratase-containing cell or a treated material of the cell under conditions where the cell does not grow, but also improves the nitrile hydratas... | 07/17/2007 |
| 7235246 | Dermatomycosis vaccine The present invention relates to the preparation of universal inactivated vaccines and their use in preparing compositions for the prophylaxis and therapy of dermatomycosis. Vaccines according to the present invention have the advantage of conferring immunity agains... | 06/26/2007 |
| 7235391 | Formulation of adenovirus for gene therapy The present invention addresses the need to improve the long-term storage stability (i.e. infectivity) of vector formulations. In particular, it has been demonstrated that for adenovirus, the use of bulking agents, cryoprotectants and lyoprotectants imparts desired ... | 06/26/2007 |
| 7229818 | Formulations to increase in vivo survival of probiotic bacteria and extend their shelf-life Disclosed is a formulation for preserving the life of probiotic bacteria during passage through the stomach, while permitting their release in the intestine, and which has a low water activity and correspondingly long shelf life. These formulations are designed to r... | 06/12/2007 |
| 7125658 | Small protein that interacts with a ribonucleotide reductase subunit and uses thereof The present invention provides for an isolated Sml1 protein or a homologue thereof. The present invention also provides for a screening assay for identifying compounds that are capable of reducing the division rate of a cell by altering an interaction between a ribo... | 10/24/2006 |
| 7122370 | Formulations to increase survival of probiotic bacteria and extend their shelf-life Disclosed is a formulation for preserving the life of probiotic bacteria during passage through the stomach, while permitting their release in the intestine, and which has a low water activity and correspondingly long shelf life. These formulations are designed to r... | 10/17/2006 |
| 7087370 | Kit for vitrifying specimens The present invention relates to systems for the vitrification of a biological specimen. The systems employ a transfer instrument such as a loop, containing a base medium that includes a cryoprotectant. The biological specimen which has undergone vitrification may b... | 08/08/2006 |
| 7052724 | Method of producing active dry yeast A novel technique is provided for drying a yeast for brewing and a method of producing alcoholic beverages by using the yeast. It is intended to provide a method of producing a dry yeast which has the optimum fermentability when directly used in fermentation and giv... | 05/30/2006 |
| 7037708 | Dried microorganism cultures and method for producing same Dry microorganism cultures comprising at least one microorganism species in carrier-bound form are present in the form of particles which a) have a particle size of at least about 0.1 mm and b) are compressed; processes for preparing dry microorganism cultures and t... | 05/02/2006 |
| 7029840 | Method for preservation of cells and nucleic acid targets The present invention provides a method for preserving cells and nucleic acids in a sample by exposing the sample to a composition that causes an inhibitory affect on proteolytic agents and/or nucleic acid degradative agents in the sample. Such compositions that are... | 04/18/2006 |
| 7022514 | Use of Acacia Gum to isolate and preserve biological material Compositions and methods for the reversible preservation of biological samples are provided. The compositions include Acacia Gum, including derivations and modifications thereof which are useful as a reversible preservation solution. A method is provided for ... | 04/04/2006 |
| 6979411 | Water treatment agent for extending water exchange intervals in tank systems A composition for long term improvement of water quality in biological tank systems is described as: 1) at least one highly or poorly soluble Al3+, Fe3+, TiO2+ or ZrO2+ salt of an organic carboxylic acid, optionally mixed ... | 12/27/2005 |
| 6969593 | Method for the selective survival or selective growth of a target cell by the use of a conjugate, its use in therapeutics and/or diagnostics and the preparation of said conjugate The invention is in particular related to a method for the selective survival or selective growth of a target cell comprising the steps of: a) contacting the target cell with a conjugate compound A-B, wherein A is a selective antibody or antibody derivative recogniz... | 11/29/2005 |
| 6960464 | Methods for lyophilizing competent cells This invention relates to a method for producing cells which are competent for transformation and which may be stably stored for extended periods of time at various temperatures. The method involves growing cells in a growth conducive medium, rendering said cells co... | 11/01/2005 |
| 6955886 | Scintillation proximity assay for the detection of peptidoglycan synthesis The invention provides a scintillation proximity assay for detecting peptidoglycan synthesis. The assay is especially suitable for high throughput screening of compounds affecting peptidoglycan synthesis. ... | 10/18/2005 |
| 6946297 | System for stabilizing samples A transport/preservation system has been found which provides safe, effective transport for patient specimens and bodily fluids, and functions as a preservative for biological reagents, therapeutics, and personal care products. The transport/preservative formulation... | 09/20/2005 |
| 6939708 | Method of rapid bio-cycling of an aquarium A method of rapid biochemical cycling of aquariums using naturally preserved granular marine substrate material, such as sand or aragonite, to rapidly denitrify the aquatic environment and to establish biochemical conditions that are favorable to the survival and vi... | 09/06/2005 |
| 6924133 | Spray dried enzyme product The invention relates to a particle comprising an enzyme and a biomass, to a process for preparing a particle comprising spray drying an enzyme and biomass containing fermentation broth starting material, to obtain a solid particle comprising an enzyme and a biomass... | 08/02/2005 |
| 6872399 | Dermatomycosis vaccine The present invention relates to the preparation of universal inactivated vaccines and their use in preparing compositions for the prophylaxis and therapy of dermatomycosis. Vaccines according to the present invention have the advantage of conferring immunity agains... | 03/29/2005 |
| 6858424 | Cryopreservation vial apparatus and methods Disclosed is a biopharmaceutical product cryopreservation system, for cryopreserving a biopharmaceutical product that includes a cryopreservation compartment; a cryopreservation fluid located within the cryopreservation compartment; and a biopharmaceutical product c... | 02/22/2005 |
| 6841168 | Method for the preservation of biologically-active material Biologically-active material can be preserved by a method of desiccation, without lyophilisation, in a matrix of glassy trehalose. The method involves forming a coacervate of the biologically-active material and chitosan and then dehydrating mixture of coacervate an... | 01/11/2005 |
| 6830922 | System and method for inoculating a biological reactor A system and method are provided for inoculating a biological reactor having a chamber. The chamber is configured to contain influent and biomass to degrade contaminants in the influent. A vessel is configured to receive influent and biomass from the chamber and to ... | 12/14/2004 |
| 6825031 | Storage of materials Materials which are not themselves storage-stable at room temperature are made suitable for storage by mixing them with a carrier substance and spray drying the resulting mixture so as to form particles containing both the material and the carrier substance in which... | 11/30/2004 |
| 6821789 | Method and device for collecting and stabilizing a biological sample A collection container and method for collecting a predetermined volume of a biological sample, and particularly a whole blood sample, includes at least one gene induction blocking agent in an amount effective to stabilize and inhibit gene induction. The gene induct... | 11/23/2004 |
| 6753182 | Cryopreservation of plant cells Methods are provided for cryopreserving plant cells and to methods for recovering viable plant cells from long or short term cryopreservation. Plant cells to be cryopreserved can be grown in culture and pretreated with a solution containing an cryorotective agent an... | 06/22/2004 |
| 6723526 | Composition for forming a dried lens-shaped pellet comprising albumin, starch, microorganisms and sugar and/or salt A composition for forming a dried lens-shaped pellet and processes therefore, are provided. The composition comprises 20 to 40% by weight albumin, about 2 to 5% by weight starch, about 40 to 90% by weight of sugar and/or salt, and about 102 to 1011 | 04/20/2004 |
| 6716632 | System for stabilizing samples A transport/preservation system has been found which provides safe, effective transport for patient specimens and bodily fluids, and functions as a preservative for biological reagents, therapeutics and personal care products. The transport/preservative formulations... | 04/06/2004 |
| 6709853 | Process for the preparation of cell beads BOD sensor useful for instant BOD estimation Immobilized cell beads incorporating formulated microbial consortium comprising a synergistic mixture of the following bacterial strains namely, Enterobacter sakazaki, Pseudomonas aeruginosa and Aeromonas sobria selected from the following isolated bac... | 03/23/2004 |
| 6689600 | Formulation of adenovirus for gene therapy The present invention addresses the need to improve the long-term storage stability (i.e. infectivity) of vector formulations. In particular, it has been demonstrated that for adenovirus, the use of bulking agents, cryoprotectants and lyoprotectants impar... | 02/10/2004 |
| 6677149 | Method for stabilizing nitrilase activity and preserving microbial cells with carbamate salts A method for preserving immobilized or unimmobilized microbial cells having nitrilase activity and for stabilizing the nitrilase activity of unimmobilized or immobilized microbial cells has been developed. Aqueous suspensions containing at least 100 mM bi... | 01/13/2004 |
| 6670184 | Method for producing a lipid emulsion for use in insect cell culture A serum-free insect cell culture medium is provided which provides improvements in the maximum insect cell density and replication of insect viruses within these cells, at a significantly lower cost than commercially-available media. A method is provided ... | 12/30/2003 |