Bizarre Patents
Crispy Chip Sandwich and Process of Producing a Sandwich Product
A food product comprising a multilayer cookie or snack having outer layers formed from a crispy type edible food product such as a potato chip or corn chip, etc. with an intermediate marshmallow layer being in contact with the inner surface of each crispy chip and one or more filler substances.
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| Number | Title | Issue Date |
| 7732188 | Protozoan strains of reduced virulence and use thereof The present invention relates to a protozoan strain of the family of the Trypanosomatidae the virulence of which is lower than that of the corresponding wild-type strain, characterized in that at least one copy of the SIR2 gene present in the genome of the strain is... | 06/08/2010 |
| 7261887 | as carriers for the delivery of proteins and peptides Methods for delivering potentially therapeutic or prophylactic protein and peptide agents to mammalian cells are provided. The agents are delivered by mutant trypanosomatid protozoa that have been genetically manipulated to code for such protein or peptide agents. T... | 08/28/2007 |
| 7238347 | Suicidal mutant vaccine The present invention discloses the use of a mutant Leishmania as a suicidal vaccine wherein the mutant Leishmania is responsive to external signals to become porphyric and commit suicidal cytolysis. The mutant can be selected from natural Leishmani... | 07/03/2007 |
| 6955890 | Method for the identification and treatment of pathogenic microorganisms infections by inhibiting one or more enzymes in an essential metabolic pathway A method for the identification and treatment of pathogenic microorganism infections by inhibiting one or more enzymes in a metabolic pathway by inhibiting the conversion of substrate to produce the penultimate or ultimate product particularly by inhibiting the acti... | 10/18/2005 |
| 6890542 | Leishmania vaccine The present invention relates to the use of a live mutant Leishmania in the preparation of a vaccine and to vaccine formulations for use in immunizing mammals, such as dogs and/or humans. The mutant Leishmania comprises at least one defective cysteine ... | 05/10/2005 |
| 6855537 | Macrophage-infecting parasites expressing a granulocyte macrophage colony stimulated factor Strains of Leishmania and other macrophage-infecting parasites are provided which express the GM-CSF gene which are useful in treating hosts infected by the parasite and in protecting hosts against disease caused by infection of hosts by parasites. The parasites are... | 02/15/2005 |
| 6652847 | Attenuated strains of leishmania and uses thereof Attenuated strains of Leishmania are provided in which at least one gene contributing to virulence of the strain and expressed in both the promastigote and amastigote forms of the strain is functionally disabled, such as, by deleting at least a portion of... | 11/25/2003 |
| 6458581 | Process for the in vitro culture of different stages of tissue parasites The present invention provides a method for carrying out in vitro the complete developmental sequence culture of tissular parasites, which includes culturing the parasites in a totally defined culture medium which is an axenic monophasic liquid culture me... | 10/01/2002 |
| 6426203 | Attenuated strains of Leishmania and uses thereof Attenuated strains of Leishmania are provided in which at least one gene contributing to virulence of the strain and expressed in both the promastigote and amastigote forms of the strain is functionally disabled, such as, by deleting at least a portion of... | 07/30/2002 |
| 6331304 | Macrophage-infecting parasites expressing a granulocyte macrophage colony stimulating factor Strains of Leishmanda and other macrophage-infecting parasites are provided which express the GM-CSF gene which are useful in treating hosts infected by the parasite and in protecting hosts against disease caused by infection of hosts by parasites. The pa... | 12/18/2001 |
| 6291217 | Glutathionylspermidine synthetase and processes for recovery and use thereof The present invention describes an enzyme showing glutathionylspermidine synthetase-activity and being distinct from known enzymes with similar activities in several physicochemical parameters, a novel process to isolate said enzyme from Crithidia fascicu... | 09/18/2001 |
| 6261523 | Adjustable volume sealed chemical-solution-confinement vessel An adjustable-volume, sealed chemical-solution-confinement vessel for enclosing the inner bottom surface of the chemical-solution-confinement vessel within a sealed chamber. The chemical-solution-confinement vessel comprises a well-shaped base into which ... | 07/17/2001 |
| 6228649 | Double targeted gene replacement in unicellular diploid organisms Homozygous gene replacement can be created in unicellular diploid organisms by individually targeting each allele of a gene with genetic constructs containing two different and independent selectable markers. Selection for both markers indicates replaceme... | 05/08/2001 |
| 6162638 | Attenuated strains of leishmania and uses thereof Attenuated strains of Leishmania are provided in which at least one gene contributing to virulence of the strain and expressed in both the promastigote and amastigote forms of the strain is functionally disabled, such as, by deleting at least a portion of... | 12/19/2000 |
| 6133017 | Attenuated strain of Leishmania Differentially expressed Leishmania genes and proteins are described. One differentially expressed gene (A2) is expressed at significantly elevated levels (more than about 10 fold higher) in the amastigote stage of the life cycle when the Leishmania organ... | 10/17/2000 |
| 6020144 | Sustained delivery device comprising a Leishmania protozoa and methods of making and using the same Disclosed herein are novel medical devices, particular well-suited for sustained delivery of therapeutically-significant substances. Also disclosed are methods of making and using these delivery devices. Using these devices and methods the present inventi... | 02/01/2000 |
| 5955333 | Double targeted gene replacement in unicellular diploid organisms Homozygous gene replacement can be created in unicellular diploid organisms by individually targeting each allele of a gene with genetic constructs containing two different and independent selectable markers. Selection for both markers indicates replaceme... | 09/21/1999 |
| 4801530 | Nucleotide hybridization assay for protozoan parasites The present invention provides a method for detection of protozoan parasites in blood or other specimen from their mammalian hosts. The method comprises nucleic acid hybridization of repetitive nuclear DNA fragments of the parasites. Hybridization probes ... | 01/31/1989 |
| 4713240 | Vaccines based on insoluble supports The present invention relates to vaccine compositions which comprise at least one antigen chemically linked to a water-insoluble support combined with a pharmaceutically acceptable carrier. It also relates to a method of stimulating an organism's immune s... | 12/15/1987 |
| 4687666 | Vaccine for Leishmaniasis Mammals immunized with an innoculum containing TLCK-treated and killed Leishmania cells show an increased resistance to Leishmaniasis.... | 08/18/1987 |
