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| Number | Title | Issue Date |
| 7615367 | strains producing stable high-molecular-mass exopolysaccharides The invention relates to the field of exopolysaccharide producing lactic acid bacteria. The invention relates to methods and culture media for producing large amounts of exopolysaccharides in safe and simple fermentation conditions. The invention more specifically r... | 11/10/2009 |
| 7575914 | Microorganism producing hyaluronic acid and purification method of hyaluronic acid The present invention relates to a hyaluronic acid producing strain Streptococcus sp. KL0188 and a method for purifying hyaluronic acid, more particularly to a Streptococcus sp. KL0188 that does not express hyaluronidase and is non-hemolytic, and a met... | 08/18/2009 |
| 7435434 | Phage resistant bacteria The invention relates to an S thermophilus bacterium which is resistant to attack by at least one bacteriophage, a method of production of the bacterium and a composition which comprises the bacterium. The bacterium comprises a modification of the Sfi21 proph... | 10/14/2008 |
| 7432365 | DNA molecules encoding beta clamp proteins of gram positive bacteria The present invention relates to beta protein-encoding genes from Gram positive bacterium. Expression systems and host cells containing these genes are also disclosed. ... | 10/07/2008 |
| 7432095 | Formate dehydrogenase tolerant to halogen compounds and process for producing the same The invention provides a formate dehydrogenase having high specific activity, small Km values for formate and NAD, broad temperature and pH ranges of stability, broad temperature and pH ranges for action, and capable of regenerating a coenzyme with good efficiency i... | 10/07/2008 |
| 7329741 | Polynucleotides that hybridize to DP-75 and their use The present invention is a novel nucleic acid sequence which hybridizes to SEQ ID NO:6 or fragments thereof under stringent conditions, or fragments thereof. The invention also includes diagnostic assays, expression vectors, control sequences, antisense molecules, r... | 02/12/2008 |
| 7323329 | Methods for production of hyaluronic acid, and isolated strains of supercapsulated streptococci Isolated strains of supercapsulated streptococci band at a density of no greater than 1.03 g/cm3 in a Percoll gradient and are capable of producing hyaluronic acid with molecular weight exceeding 6 million Da. Methods of producing high molecular we... | 01/29/2008 |
| 7323175 | Immunogenicity of glucan binding protein Immunogenic compositions and subunit vaccines for dental caries are described which comprise peptide subunits of glucan binding protein-B and peptide subunits of glucan binding protein-B in combination with peptide subunits of glucosyltransferase. Methods of provoki... | 01/29/2008 |
| RE40023 | Dietary and pharmaceutical compositions containing lyophilized lactic bacteria, their preparation and use A pharmaceutical composition containing several different bacteria including Streptococcus thermophilus, Lactobacilli and Bifidobacteria is disclosed. The bacteria are present in the composition at a total concentration of 1×1011 to 1×1013 pe... | 01/22/2008 |
| 7294501 | Geldanamycin-producing strains, uses thereof and methods of producing same A use of an inoculum of a geldanamycin-producing strain able to survive in a plant rhizosphere as a biocontrol of common scab affecting the plant and a method for biocontrolling common scab comprising the use of such strain. A biologically pure culture of a Strep... | 11/13/2007 |
| 7241610 | Lactic acid bacteria overproducing exopolysaccharides The invention concerns lactic acid bacteria overproducing exopolysaccharides following mutation in the gene coding for α-phosphoglucomutase. Said mutants are useful, in particular for preparing fermented products or for producing exopolysaccharides. ... | 07/10/2007 |
| 7238351 | Immunogen adherence inhibitor directed to lactic acid producing organisms and method of making and using it The method of producing a microbial adherence inhibitor for administration to food animals to control the incidents of acidosis in food animals by preventing the adherence of colony-forming lactic acid producing bacteria in the rumen or intestinal tracts of the food... | 07/03/2007 |
| 7223591 | Strain of lactic acid bacterium and edible compositions, drugs and veterinary products containing it Describes a new strain of Streptococcus thermophilus ssp. salivarius (deposited on 4 Dec. 2001 at the DSMZ—Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH, Braunschweig, Germany, with accession No. DSM 14667) and edible compositions, drug... | 05/29/2007 |
| 7189398 | Broad spectrum pyrogenic exotoxins antagonists and vaccines The invention relates to peptides having an amino acid sequence substantially homologous to an amino sequence of a domain of a pyrogenic exotoxin, which domain forms a central turn in the exotoxin starting within β-strand 7 and connecting the β-strand 7, via short... | 03/13/2007 |
| 7179628 | Transglutaminase A DNA molecule encoding transglutaminase, a transglutaminase, an expression vector containing the DNA molecule, and a cell containing the expression vector. ... | 02/20/2007 |
| 7163682 | Glucan binding protein and glucosyltransferase immunogens Immunogenic compositions and subunit vaccines for dental caries are described which comprise peptide subunits of glucan binding protein-B and peptide subunits of glucan binding protein-B in combination with peptide subunits of glucosyltransferase. Methods of provoki... | 01/16/2007 |
| 7157258 | Particles containing coated living micro-organisms, and method for producing same Particles containing dehydrated living micro-organisms are coated with a homogeneous layer of hydrophobic substance selected to reduce the risks of degradation of the micro-organisms by physico-chemical stresses such as heat, humidity, gastric acid, or compression. ... | 01/02/2007 |
| 7125548 | vaccines and diagnostic tests The invention relates to Streptococcus suis infection in pigs, vaccines directed against those infections and tests for diagnosing Streptococcus suis infections. The invention provides an isolated or recombinant nucleic acid encoding a capsular gene cl... | 10/24/2006 |
| 7056517 | Glucosyltransferase immunogens Vaccine compositions and immunogenic compositions are described which are glucosyltransferase subunit vaccines for dental caries and which contain at least one peptide which corresponds to a sequence of glucosyltransferase containing aspartate 413, an equivalent of ... | 06/06/2006 |
| 7056510 | Streptococcus pneumoniae SP036 polynucleotides, polypeptides, antigens and vaccines The present invention relates to novel vaccines for the prevention or attenuation of infection by Streptococcus pneunoniae. The invention further relates to isolated nucleic acid molecules encoding antigenic polypeptides of Streptococcus pneumoniae. An... | 06/06/2006 |
| 7056697 | FabK variant The invention provides FabK polypeptides and polynucleotides encoding FabK polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing FabK polypeptides to screen for antibacterial compounds. ... | 06/06/2006 |
| 7033795 | FabK variant The invention provides FabK polypeptides and polynucleotides encoding FabK polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are preferred methods for utilizing FabK polypeptides and polynucleotides as diagnostic reage... | 04/25/2006 |
| 7008785 | Micro-organisms with glycosylation modulating action of intestinal cell surface The invention concerns micro-organism strains, in particular of lactic acid bacteria, having a glycosylation modulating effect of intestinal cell surface. The invention also concerns a method for selecting micro-organism strains, in particular of lactic acid bacteri... | 03/07/2006 |
| 6994997 | Gram positive bacteria deprived of HtrA protease activity and their uses The invention concerns bacteria strains, obtained from gram-positive bacteria whereof the genome size is not more than 3.2 Mb, and wherein the HtrA surface protease is inactive. Said strains are useful for expressing exported proteins of interest. ... | 02/07/2006 |
| 6995134 | Use of yneS, essential bacterial genes and polypeptides Disclosed is a gene, termed “S-yneS,” found in Streptococcus pneumoniae, which is essential for survival for a wide range of bacteria. This gene and the S-yneS polypeptide that it encodes, as well as homologs and orthologs thereof (collectively referred t... | 02/07/2006 |
| 6875601 | Mutant Lactobacillus bulgaricus strains free from β-galactoside activity The invention concerns mutant L. bulgaricus strains bearing a nonsense mutation, in at least one of the sequences coding for the lactose operon, and free from β-galactosidase activity, and lactic starters comprising said strains. Said strains and starters ca... | 04/05/2005 |
| 6835818 | Mutants of Streptococcal toxin C and methods of use This invention is directed to mutant SPE-C toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred SPE-C toxin has at least one amino acid change and is substantially non-l... | 12/28/2004 |
| 6827936 | Synthetic peptide vaccines for dental caries Vaccine compositions and immunogenic compositions are described which are glucosyltransferase subunit vaccines for dental caries and which contain at least one peptide which corresponds to a sequence of glucosyltransferase containing aspartate 413, an equivalent of ... | 12/07/2004 |
| 6818624 | Therapeutic agent for a cancer and method of screening the same, and health-care auxillary food A therapeutic agent for a cancer comprising a therapeutically effective amount of an active ingredient, wherein the therapeutic agent is used referring to an ability of acting on NK cell antigen receptor NKR-P1 of NKT cell as an index of the ability to activate the ... | 11/16/2004 |
| 6777547 | Collagen-binding proteins from streptococcus pyogenes Isolated proteins, designated Cpa1 and Cpa49, and their corresponding amino acid and nucleic acid sequences are provided which are useful in the prevention and treatment of infection caused by group A streptococcal bacteria such as Streptococcus pyogenes. The... | 08/17/2004 |
| 6773912 | Lantibiotic This invention provides an antibacterial protein, Salivaricin B. Salivaricin B is bacteriocidal with respect to, inter alia, S. pyogenes and therefore has numerous therapeutic applications. These applications include, but are not limited to, forming part of t... | 08/10/2004 |
| 6737245 | Luciferase expression cassettes and methods of use The present invention relates to bacterial luciferase expression cassettes suitable for conferring bioluminescence properties on Gram-positive bacteria, cells transformed with such cassettes, and methods of making and using such cassettes. ... | 05/18/2004 |
| 6737521 | Delivery and expression of a hybrid surface protein on the surface of gram positive bacteria Process is described for the delivery and expression of hybrid surface proteins to the surface of bacteria. The transformed bacteria are useful as vaccines, for the delivery of other active peptides to animal hosts, as diagnostic reagents and for other purposes.... | 05/18/2004 |
| 6696057 | Composition and method for treatment of gastrointestinal disorders and hyperlipidemia A probiotic composition and method for the treatment of gastrointestinal disorders, hyperlipidemia and autoimmune diseases. The probiotic composition comprises a culture having lactobacillus bulgaricus and streptococcus thermophilus lactic acid bacteria a... | 02/24/2004 |
| 6696287 | System for co-culturing bacteria and eukaryotic cells The present invention is directed to an apparatus that can be used for co-culturing bacteria and eukaryotic cells. The apparatus allows the bacteria to be grown under steady state conditions and then perfused over the eukaryotic cells. The invention also ... | 02/24/2004 |
| 6686192 | Antisense RNA expression strategies effective against Streptococcus thermophilus bacteriophages Recombinant bacteria containing nucleotide sequences encoding Streptococcus thermophilus phage helicase and primase genes expressed in the antisense orientation and methods of making and using the same are disclosed. Replication of bacteriophage infecting... | 02/03/2004 |
| 6682745 | Use of bacterium for manufacture of a vaccine The present invention relates to the use of live attenuated bacteria for the manufacture of a vaccine for submucosal administration.... | 01/27/2004 |
| 6624140 | Synthetic peptides with antimicrobial and endotoxin neutralizing properties for management of the sepsis syndrome A peptide with an amino acid composition such that the peptide is amphipathic, cationic and forms a stable -helix and has the following structure comprising at least 12 amino acids said peptide has either the orientation according to the formula or the ... | 09/23/2003 |
| 6613549 | Probiotic therapy for newborns The invention relates to probiotic microbes, including but not limited to Lactobacillus species and Bifidobacteria species, and their compositions and methods of employing said compositions for treating and preventing intestinal and other infections which... | 09/02/2003 |
| 6579711 | Lactic acid bacteria species Strain of lactic acid bacterium, (1) whose 16S ribosomal RNA is characteristic of the genus Streptococcus, (2) whose total protein profile, obtained after migration of the total proteins on an SDS-PAGE electrophoresis gel, is characteristic of that of the... | 06/17/2003 |
