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| Number | Title | Issue Date |
| 7442522 | Nucleic acids encoding chromo or fluorescent proteins and method for using the same Nucleic acid compositions encoding novel chromo/fluoroproteins and mutants thereof, are provided. The subject proteins of interest are proteins that are colored and/or fluorescent, where this feature arises from the interaction of two or more residues of the protein... | 10/28/2008 |
| 7442521 | Nucleic acids encoding chromophores/fluorophores and methods for using the same Nucleic acid compositions encoding novel chromo/fluoroproteins and mutants thereof are provided. The subject proteins of interest are proteins that are colored and/or fluorescent, where this feature arises from the interaction of two or more residues of the protein.... | 10/28/2008 |
| 7439038 | Method for producing L-amino acid using methylotroph A DNA encoding for a mutant of LysE protein, or a homologous protein thereof, of a coryneform bacterium, wherein the mutant, when introduced into a methanol-assimilating bacterium imparts resistance to L-lysine analogue. The DNA encoding for a mutant of LysE protein... | 10/21/2008 |
| 7427493 | Recombinant genes for polyketide modifying enzymes Materials and methods to produce modified polyketides are disclosed. The biosynthesis, transfer and regulator genes for various sugars to effectuate polyketide modification are disclosed. ... | 09/23/2008 |
| 7427593 | Methods of making triacylglycerol using phospholipid:Diacylglycerol acyltransferase The present invention relates to the production of triacylglycerol in a transformed organism or host cell, by means of a nucleotide sequence from S. cerevisiae, whereby said enzyme catalyzes the transfer of fatty acids from phospholipids to diacylglycerol in ... | 09/23/2008 |
| 7419803 | Nucleic acids encoding human coagulation Factor VII polypeptides The present invention relates to novel human coagulation Factor VIIa variants having coagulant activity as well as polynucleotide constructs encoding such variants, vectors and host cells comprising and expressing the polynucleotide, pharmaceutical compositions, use... | 09/02/2008 |
| 7416861 | Human coagulation factor VII polypeptides The present invention relates to novel human coagulation Factor VIIa variants having coagulant activity as well as polynucleotide constructs encoding such variants, vectors and host cells comprising and expressing the polynucleotide, pharmaceutical compositions, use... | 08/26/2008 |
| 7416860 | Nucleic acids encoding human coagulation factor VII variants The invention concerns nucleic acids encoding coagulation Factor VII variants in which the Leu residue in position 305 has been replaced by another amino acid residue. The invention further concerns the expression of such nucleic acids resulting in a Factor VII vari... | 08/26/2008 |
| 7413878 | Recombinant host cells expressing atoAD and capable of making a polyketide using a starter unit Host cells, such as E. coli, are provided with an expression system for making starter units required for biosynthesis of polyketides using the ato pathway. ... | 08/19/2008 |
| 7413874 | Nucleic acid encoding fluorescent proteins from aquatic species Provided are four new fluorescent proteins. The proteins were derived from two wild-type fluorescent proteins: a red fluorescent protein (RFP) that was isolated from Actinodiscus or Discosoma sp. 1 and a green fluorescent protein (GFP) isolated from | 08/19/2008 |
| 7364729 | Method of inducing a CTL response Disclosed herein are methods for inducing an immunological CTL response to an antigen by sustained, regular delivery of the antigen to a mammal so that the antigen reaches the lymphatic system. Antigen is delivered at a level sufficient to induce an immunologic CTL ... | 04/29/2008 |
| 7364877 | Polynucleotides encoding disorazole polyketide synthase polypeptides The sequence of the disorazole polyketide synthase protein gene is disclosed. Domains of disorazole polyketide synthase and polynucleotides encoding them are provided. Methods to prepare disorazoles in pharmaceutically useful quantities are described, as are methods... | 04/29/2008 |
| 7358076 | Sublancin lantibiotic produced by 168 An antimicrobial peptide produced by Bacillus subtilis 168 was isolated and characterized and named sublancin 168. The invention includes DNA encoding for the sublancin 168 peptides and peptides which are at least 80% identical to the sublancin 168 peptide. T... | 04/15/2008 |
| 7354708 | Invasion assays The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence... | 04/08/2008 |
| 7354754 | Microorganism sensitive to lysozyme A microorganism of the genus Rhodococcus is provided which has a higher sensitivity to lysozyme at a low concentration than a wild-type strain, which can easily cause cell lysis, and from which a recombinant protein expressed therein is easily recovered. More... | 04/08/2008 |
| 7344862 | Nucleic acids encoding chromophores/fluorophores and methods for using the same Nucleic acid compositions encoding novel chromo/fluoroproteins and mutants thereof, are provided. The subject proteins of interest are proteins that are colored and/or fluorescent, where this feature arises from the interaction of two or more residues of the protein... | 03/18/2008 |
| 7341831 | Method for immuno-detection of epitopes Methods, systems and kits are provided for detecting, molecules expressing a selected epitope in a sample through use of an epitope detector containing a single chain Fv for the selected epitope or a constrained epitope specific CDR attached to an oligonucleotide. | 03/11/2008 |
| 7338784 | Nucleic acids encoding chromophores/fluorophores and methods for using the same Nucleic acid compositions encoding novel chromo/fluoroproteins and mutants thereof, are provided. The subject proteins of interest are proteins that are colored and/or fluorescent, where this feature arises from the interaction of two or more residues of the protein... | 03/04/2008 |
| 7338783 | Nucleic acids encoding chromophores/fluorophores and methods for using the same Nucleic acid compositions encoding novel chromo/fluoroproteins and mutants thereof, are provided. The subject proteins of interest are proteins that are colored and/or fluorescent, where this feature arises from the interaction of two or more residues of the protein... | 03/04/2008 |
| 7338782 | Nucleic acids encoding chromophores/fluorophores and methods for using the same Nucleic acid compositions encoding novel chromo/fluoroproteins and mutants thereof, are provided. The subject proteins of interest are proteins that are colored and/or fluorescent, where this feature arises from the interaction of two or more residues of the protein... | 03/04/2008 |
| 7338785 | Nucleic acids encoding chromophores/fluorophores and methods for using the same Nucleic acid compositions encoding novel chromo/fluoroproteins and mutants thereof, are provided. The subject proteins of interest are proteins that are colored and/or fluorescent, where this feature arises from the interaction of two or more residues of the protein... | 03/04/2008 |
| 7319028 | Process for producing sporangia of , control agent, and controlling method The present invention provides a process for efficiently producing sporangia of Bacillus popilliae containing spores and parasporal bodies having controlling effects on Scarabaeidae insects, and a control agent and controlling method for Scarabaeida... | 01/15/2008 |
| 7314736 | Nucleic acids encoding oxidation-reduction sensitive green fluorescent protein variants The disclosure provides proteins that can be used to determine the redox status of an environment (such as the environment within a cell or subcellular compartment). These proteins are green fluorescent protein (GFP) variants (also referred to as redox sensitive GFP... | 01/01/2008 |
| 7300786 | Bacteria of the family having enhanced transaldolase activity A method is provided for producing L-histidine using bacterium of the Enterobacteriaceae family, wherein the L-amino acid productivity of said bacterium is enhanced by enhancing an activity of the transaldolase encoded by the talb gene. ... | 11/27/2007 |
| 7294493 | Nucleic acid fragments encoding nitrile hydratase and amidase enzymes from 5-MGAM-4D and recombinant organisms expressing those enzymes useful for the production of amides and acids The invention relates to the isolation, sequencing, and recombinant expression of genes encoding either a nitrile hydratase (NHase) or amidase (Am) from Comamonas testosteroni 5-MGAM-4D, where the NHase is useful for catalyzing the hydration of nitriles to th... | 11/13/2007 |
| 7291711 | Fluorescent proteins from aquatic species Provided are four new fluorescent proteins. The proteins were derived from two wild-type fluorescent proteins: a red fluorescent protein (RFP) that was isolated from Actinodiscus or Discosoma sp. 1 and a green fluorescent protein (GFP) isolated from | 11/06/2007 |
| 7267983 | Peptides for use in culture media The present invention provides peptides libraries which are useful for rapid identification of biologically active compounds. The invention further provides peptides which include cell-growth affecting peptides and peptides which enhance or inhibit production of cel... | 09/11/2007 |
| 7226764 | Compositions and methods for the synthesis and subsequent modification of uridine-5′-diphosphosulfoquinovose (UDP-SQ) The present invention is directed to compositions and methods related to the synthesis and modification of uridine-5′-diphospho-sulfoquinovose (UDP-SQ). In particular, the methods of the present invention comprise the utilization of recombinant enzymes from Ara... | 06/05/2007 |
| 7186531 | L-threonine producing bacterium belonging to the genus and method for producing L-threonine There is disclosed a method for producing L-threonine using bacterium belonging to the genus Escherichia wherein the bacterium has been modified to enhance an activity of aspartate-β-semialdehyde dehydrogenase. ... | 03/06/2007 |
| 7176014 | Solid culture medium and method for preparing the same A solid medium having a 10 minute-average water absorption rate of at least 0.05 ml/minute, which is obtainable by a method for producing a solid medium comprising the steps of dissolving components of the solid medium other than solvent water into the solvent water... | 02/13/2007 |
| 7160698 | Fluorescent and colored proteins, and polynucleotides that encode these proteins The subject invention provides new fluorescent and/or colored proteins, and polynucleotide sequences that encode these proteins. The subject invention further provides materials and methods useful for expressing these detectable proteins in biological systems. ... | 01/09/2007 |
| 7122364 | FEN endonucleases The present invention provides novel cleavage agents and polymerases for the cleavage and modification of nucleic acid. The cleavage agents and polymerases find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucl... | 10/17/2006 |
| 7122176 | Mycoattractants and mycopesticides The present invention utilizes the pre-sporulation (preconidial) mycelial stage of entomopathogenic fungi as insect attractants and/or pathogens. The fungus can be cultivated on grain, wood, agricultural wastes or other cellulosic material, attracting the insect and... | 10/17/2006 |
| 7091317 | Fluorescent proteins The present invention provides novel engineered derivatives of green fluorescent protein (GFP) which have an amino acid sequence which is modified by amino acid substitution compared with the amino acid sequence of wild type Green Fluorescent Protein. The modified G... | 08/15/2006 |
| 7011944 | Invasive cleavage of nucleic acids The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence... | 03/14/2006 |
| 7001986 | Fluorescent proteins A GFP with an F64L mutation and an E222G mutation is provided. This GFP has a bigger Stokes shift compared to other GFPs making it very suitable for high throughput screening due to a better resolution. This GFP also has an excitation maximum between the yellow GFP ... | 02/21/2006 |
| 6994851 | Method of inducing a CTL response A method of inducing a cytotoxic T-lymphocyte (CTL) response to an antigen is disclosed. The method involves delivering the antigen to the lymphatic system of an animal regularly over a sustained period of time using, e.g., an osmotic pump. The method is advantageou... | 02/07/2006 |
| 6977074 | Method of inducing a CTL response Disclosed herein are methods for inducing an immunological CTL response to an antigen by sustained, regular delivery of the antigen to a mammal so that the antigen reaches the lymphatic system. Antigen is delivered at a level sufficient to induce an immunologic CTL ... | 12/20/2005 |
| 6972282 | Process for producing a product containing antihypertensive tripeptides The invention relates to a process for preparing a product containing antihypertensive peptides by fermenting a casein-containing starting material with lactic acid bacteria. The invention also relates to the obtained product and its use as a functional product as s... | 12/06/2005 |
| 6753177 | P-glycoproteins and uses thereof The invention pertains to dog P-glycoproteins and related P-glycoproteins which include dog-specific amino acids, as well as nucleic acids which encode those polypeptides. The present invention also includes fragments and biologically functional variants of the dog ... | 06/22/2004 |