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| Number | Title | Issue Date |
| 7285406 | Nucleic acid fragments encoding nitrile hydratase and amidase enzymes from 5-MGAM-4D and recombinant organisms expressing those enzymes useful for the production of amides and acids The invention relates to the isolation, sequencing, and recombinant expression of genes encoding either a nitrile hydratase (NHase) or amidase (Am) from Comamonas testosteroni 5-MGAM-4D, where the NHase is useful for catalyzing the hydration of nitrites to th... | 10/23/2007 |
| 7141244 | proteins useful for vaccines and diagnostics This invention provides polypeptides of Helicobacter pylori cytotoxin associated immunodominant (CAI) antigen. The invention also provides prophylactic and therapeutic vaccines comprising polypeptides of Helicobacter pylori CAI antigen, and methods for... | 11/28/2006 |
| 6872563 | Compositions and methods for production of disulfide bond containing proteins in host cells The invention provides composition and methods for producing proteins of interest which comprise at least one disulfide bond, include proteins which in their mature form do not contain disulfide bonds, but whose precursor molecule contained at least one disulfide bo... | 03/29/2005 |
| 6787348 | Liquid starter cultures having improved storage stability and use thereof Liquid microbial starter culture that retains its initial metabolic activity during storage for extended periods of time. Such liquid starter cultures are useful in the manufacturing of food and feed products. Starter cultures of the invention include culture of lac... | 09/07/2004 |
| 6258566 | Production of polyketides in bacteria and yeast Hybrid and novel polyketide synthases (PKSs) and polyketides are produced by use of a multiple vector system. The combinatorial possibilities offered by placing the various catalytic activities of PKS systems on separate vectors permits the construction o... | 07/10/2001 |
| 6210665 | Bacillus mycoides strain for controlling insects A novel pesticidal metabolite-producing B. mycoides strain is provided. In addition, a supernatant of the novel strain with pesticidal activity is provided. A water-soluble, small molecular weight ( | 04/03/2001 |
| 6194383 | Lipopeptides from actinoplanes sp. with pharmacological action, process for their production and the use thereof The invention relates to lipopeptides with very homologous amino-acid sequences but different fatty acid residues (lipid portion) which are synthesized by Actinoplanes sp. during fermentation and are released into the culture medium, to a process for isol... | 02/27/2001 |
| 5906818 | Bacillus mycoides strain for controlling corn rootworm A novel pesticidal metabolite-producing B. mycoides strain is provided. In addition, a supernatant of the novel strain with pesticidal activity is provided. A water-soluble, small molecular weight ( | 05/25/1999 |
| 5900372 | Method for the culture of microorganisms of the genera helicobacter, campylobacter and arcobacter employing culture media comprising cycodextrin Method for the culture of microorganisms of the genera Helicobacter, Campylobacter and Arcobacter, wherein culture media are employed, which comprise, in place of blood or its derivative, cyclodextrins, methylcellulose or mixtures thereof.... | 05/04/1999 |
| 5824537 | Processes for the in vitro culture, attenuation of the virulence and cloning of parasites of the genus babesia and their applications The present invention provides a process for the in vitro culture of parasites of the genus Babesia, processes for the in vitro attenuation of the virulence of these parasites, processes for the in vitro cloning of these parasites, attenuated parasites, c... | 10/20/1998 |
| 5627057 | Inhibitor compounds of farnesyl-protein transferase and chemotherapeutic compositions containing the same, produced by strain ATCC 55532 The present invention is directed to compounds which inhibit farnesyl-protein transferase (FPTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this inven... | 05/06/1997 |
| 5378463 | Antitumor antibiotic A certain fermentation product of Actinomadura strain Q473-8 yield, when suitably treated, a novel compound having both antibiotic and antitumor activities.... | 01/03/1995 |
| 5270187 | Microbial transformation product Described is a process for producing a new immunosuppressant, L-682,992, a C-13, C-31 demethylated ring-rearranged analog of L-679,934, under novel fermentation conditions utilizing the microorganism, Actinoplanacete Sp., (Merck Culture Collection MA 6559... | 12/14/1993 |
| 5238830 | Microbiological process for the production of 6-hydroxypicolinic acid A microbiological process for the production of 6-hydroxypicolinic acid starting from picolinic acid and/or its salts. The concentration of picolinic acid and/or its salts is selected so that the 6-hydroxypicolinic acid is not further metabolized. The pro... | 08/24/1993 |
| 5202258 | Immunosuppressant-producing culture Described is a new microorganism, Actinoplanacete sp., (Merck Culture Collection MA 6559) ATCC No. 53771. The microorganism acts as a demethylating agent and can produce the new immunosuppressants, "demethomycin" (L-682,993) a C-31 demethylated analog of ... | 04/13/1993 |
| 5182197 | Microbiological process for the production of 6-hydroxypicolinic acid A microbiological process for the production of 6-hydroxypicolinic acid starting from picolinic acid and/or its salts. The concentration of picolinic acid and/or its salts is selected so that the 6-hydroxypicolinic acid is not further metabolized. The pro... | 01/26/1993 |
| 5145786 | Preenriched broth medium for the simultaneous sampling of foods for salmonella and listeria This invention relates to a preenrichment broth medium that allows for the simultaneous sampling for Salmonella and Listeria spp. The medium allows for the recovery of sublethally injured bacteria that would otherwise be overlooked by conventional techniq... | 09/08/1992 |
| 5126350 | Polycyclic aromatic antifungal compounds A compound represented by the formula I: ##STR1## wherein R1 and R2 are independently hydrogen or (C2 -C10) alkanoyl in substantially chemically pure form, and pharmaceutical compositions thereof are disclo... | 06/30/1992 |
| 5085990 | Teicoplanin-like derivatives The present invention relates to new teicoplanin-like antibiotics differing from the parent compound in the length of the acyl group. The compounds of the invention are obtained according to a microbiological process and possess an antimicrobiol activity mainl... | 02/04/1992 |
| 4992369 | Fermentation process for glycopeptide antibiotic A new glycopeptide antibiotic UK-68,597 can be prepared by submerged aerobic propagation in aqueous nutrient media of Actinoplanes sp. ATCC 53533. The antibiotic and its cationic salts are active against a variety of microorganisms and are effective in co... | 02/12/1991 |
| 4981792 | Immunosuppressant compound Described is a process for producing a new immunosuppressant, "demethomycin" (L-682,993) a C-31 demethylated analog of L-679,934 under novel fermentation conditions utilizing the microorganism, Actinoplanacete sp., (Merck Culture Collection MA 6559) ATCC ... | 01/01/1991 |
| 4859599 | Antibiotic A26201-1 and antibiotic A26201-2 produced by a novel strain of actinoplanes Antibiotic A26201-1 and antibiotic A26201-2 are produced by the novel microorganism, Actinoplanes species A26201 (ATCC 39573), under aqueous aerobic fermentation conditions. The antibiotics are useful for inhibiting bacteria, particularly gram positive ba... | 08/22/1989 |
| 4637981 | Antibiotic A-4696 factor G Glycopeptide antibiotic A-4696G is produced by culturing Actinoplanes missouriensis mutant strain ATCC 31681 under submerged aerobic fermentation conditions, and is recovered from the fermentation broth by resin adsorption and chromatographic purification... | 01/20/1987 |
| 4587218 | Novel bioconverting microorganisms New Actinoplanes missouriensis strains CUC 014 (NRRL 15647) and CSV 558 (NRRL 15646) which operate together to cosynthesize the useful glycopeptide antibiotic CUC/CSV.... | 05/06/1986 |
| 4332902 | Antibiotic substance A novel antibiotic substance, named "Mycoplanecin", of presently unknown structural formula, is produced by cultivating a Mycoplanecin-producing microorganism of the genus Actinoplanes, especially the Actinoplanes nov. sp. Strain No. 41042, NRRL No. 11462... | 06/01/1982 |
| 4328316 | Biologically pure culture of actinoplanes capable of producing antibiotic A/16686 The present invention relates to a glycopeptide antibiotic arbitrarily designated as A/16686 antibiotic, and to its physiologically-acceptable acid addition salts. Antibiotic A/16686 free base, and its acid addition salts are antibacterial agents, especia... | 05/04/1982 |
| 4280001 | Biologically pure culture A biologically pure culture of Actinoplanes sarveparensis.... | 07/21/1981 |
| 4276382 | Antibiotic substances The antibiotic gardimycin and process for producing said antibiotic by fermentation of strains belonging to the genus Actinoplanes.... | 06/30/1981 |
