Did You Know...
...that after Parker Brothers executives turned down the game of Monopoly because it had "52 fundamental errors" (including taking too long to play), a copy of the game wound up in the home of the company president who stayed up until 1 a.m. to finish playing it? He was so impressed by the game that the next day he wrote to inventor Charles Darrow and offered to buy it!
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| Number | Title | Issue Date |
| 8183028 | Methods and compositions for producing olefins Compositions and methods for producing olefins are described herein. The olefins can be used to produced biofuels. ... | 05/22/2012 |
| 8178337 | nucleic acid sequences encoding carbohydrate utilization-related proteins and uses therefor Carbohydrate utilization-related and multidrug transporter nucleic acids and polypeptides, and fragments and variants thereof, are disclosed in the current invention. In addition, carbohydrate utilization-related and multidrug transporter fusion proteins, antigenic ... | 05/15/2012 |
| 8168421 | Microbial vaccine and vaccine vector The present invention includes cold-adapted, acid-fast bacterium for use as a vaccine and a vaccine vector. In preferred embodiments, the cold-adapted, acid-fast bacterium is a Mycobacteria, for example, Mycobacteria shottsii. ... | 05/01/2012 |
| 8168422 | Microorganism producing inosine and method of producing inosine using the same The present invention relates to a microorganism producing inosine, which is one of purine nucleoside, an important material for 5′-inosinic acid synthesis, and method for producing inosine using the same. More particularly, the present invention relates to a reco... | 05/01/2012 |
| 8163532 | Microorganisms with a reactivation system for cob(I)alamin-dependent methionine synthase The present invention relates to microorganisms and methods for producing methionine by reactivation of the MetH enzyme. ... | 04/24/2012 |
| 8148136 | Diagnostics and vaccines for mycobacterial infections of animals and humans This invention relates to the protein, Mycobacterium paratuberculosis acylase (mpa) and the gene encoding mpa, which we have identified in the pathogen Mycobacterium paratuberculosis Mptb (also designated Mycobacterium avium subspecies paratu... | 04/03/2012 |
| 8137950 | Bacteriophage resistant lactic acid bacteria A lactic acid bacterium (LAB) wherein an YjaE protein is essentially inactive and the LAB thereby get improved resistance to bacteriophages, a starter culture composition comprising the lactic acid bacterium and use of this starter culture manufacturing a food or fe... | 03/20/2012 |
| 8129167 | UL16 binding protein 4 ULBP4, a novel member of the ULBP family has been isolated and characterized. ULBP4 is a useful activator of immune effector cells, particularly of NK cells. Nucleic acids encoding ULBP4, vectors, and cells encoding the same are provided. ... | 03/06/2012 |
| 8129170 | Recombinant bacteria having the ability to metabolize sucrose Recombinant bacteria capable of metabolizing sucrose are described. The recombinant bacteria comprise in their genome or on at least one recombinant construct: a nucleotide sequence from Pseudomonas fluorescens Pf5 (ATCC® BAA-477) encoding a polypeptide havi... | 03/06/2012 |
| 8129169 | Microorganisms for the production of 1,4-butanediol and related methods The invention provides non-naturally occurring microbial organisms comprising a 1,4-butanediol (BDO) pathway comprising at least one exogenous nucleic acid encoding a BDO pathway enzyme expressed in a sufficient amount to produce BDO and further optimized for expres... | 03/06/2012 |
| 8129168 | Recombinant colwellia psychrerythraea alkaline phosphatase and uses thereof A heat labile alkaline phosphatase enzyme and methods of using the same and kits including the same are disclosed. Specifically, a nucleotide sequence of, peptide sequence of, methods of using, and kits comprising, a heat labile alkaline phosphatase isolated from | 03/06/2012 |
| 8129166 | Immunogenic minicells and methods of use The disclosed invention relates to immunogenic minicells cells (anucleated) and their use to induce an immune response from a subject. ... | 03/06/2012 |
| 8124399 | Enhanced protein expression in The present invention provides cells that have been genetically manipulated to have an altered capacity to produce expressed proteins. In particular, the present invention relates to Gram-positive microorganisms, such as Bacillus species having enhanced expre... | 02/28/2012 |
| 8119389 | strain The present invention relates to a process for preparing (2R,3S)-1-halo-2-hydroxy-3-(protected)amino-4-substituted butane comprising contacting a mutagenized Rhodococcus erythropolis having ATCC deposit no. PTA-6648 with (3S)-1-halo-2-oxo-3-(protected)amino-4... | 02/21/2012 |
| 8105816 | Nucleic acid molecules encoding BANK1 splice variants The present invention relates to a new splice variant of BANK1, the use of SNPs in BANK1 for diagnostics and the use of antagonists to modulate BANK1 and/or the BANK1 pathway. ... | 01/31/2012 |
| 8101398 | Modified cellulases with increased thermostability, thermophilicity, and alkalophilicity A modified Family 6 cellulase enzyme comprising a proline residue at position 413 is provided. Genetic constructs and genetically modified microbes comprising DNA sequences encoding the modified Family 6 cellulase are also provided. Family 6 cellulases of the invent... | 01/24/2012 |
| 8097446 | strain CYL1892 This disclosure presents embodiments of novel strains of Staphylococcus aureus that through genetic engineering produce type 5 capsular polysaccharide at greater levels than Staphylococcus aureus strain Reynolds. ... | 01/17/2012 |
| 8084243 | Blocking sporulation by inhibiting SpoIIE We have shown that the control of solventogenesis and sporulation can be genetically uncoupled in C. acetobutylicum. In strain 824(pASspo), the absence of SpoIIE causes sporulation to be blocked at stage II. The cell remains in a vegetative state, and this al... | 12/27/2011 |
| 8080402 | Surface expression method of peptides P5 and Anal3 using the gene encoding poly-gamma-glutamate synthetase The present invention relates to a method for expressing each of peptide antibiotics P5 3 and Anal3 35 having amphiphilicity and showing antibacterial, antifungal and anticancer activities 61, 63, 65, 67, 69, 71, on the microbial surface, using a vector containing o... | 12/20/2011 |
| 8076120 | 3-hydroxypropionic acid and other organic compounds Methods and materials related to producing 3-HP as well as other organic compounds are disclosed. Specifically, isolated nucleic acids, polypeptides, host cells, and methods and materials for producing 3-HP and other organic compounds are disclosed. ... | 12/13/2011 |
| 8071356 | strains of reduced pathogenicity, method for their preparation and uses thereof The invention concerns novel Salmonella enterica attenuated strains, characterized in that they are inactivated at the level of the znuABC operon through mutation in at least one of the znuA, znuB, znuC genes of such operon, for uses in medical or veterinary ... | 12/06/2011 |
| 8071355 | Polyhydroxyalkanoate production by coenzyme A-dependent aldehyde dehydrogenase pathways Organisms are provided containing genes encoding one or more enzymes, Coenzyme-A-dependent aldehyde dehydrogenase, acyl-CoA transferase, acyl-CoA synthetase, β-ketothiolase, acetoacetyl-CoA reductase and/or PHA synthase. In some cases one or more of these genes are... | 12/06/2011 |
| 8067224 | Presenilin associated membrane protein (PAMP) and uses thereof Presenilin Associated Membrane Protein (PAMP), and nucleic acids encoding this protein, are provided. PAMP and PAMP nucleic acids provide diagnostic and therapeutic tools for evaluating and treating or preventing neurodegenerative diseases. In a specific embodiment,... | 11/29/2011 |
| 8058052 | Isolated genomic polynucleotide fragments from chromosome 12 that encode human carboxypeptidse M The invention is directed to isolated genomic polynucleotide fragments that encode human carboxypeptidase M and human mouse double minute 2 homolog, vectors and hosts containing these fragments and fragments hybridizing to noncoding regions as well as antisense olig... | 11/15/2011 |
| 8048666 | Ethanol production in microorganisms The present disclosure relates to methods and compositions for engineering photoautotrophic organisms to convert carbon dioxide and light into fatty acid esters and other molecules, including biofuels. The molecules are then secreted by the organism into a growth me... | 11/01/2011 |
| 8043841 | Nucleic acid molecules encoding alanine 2,3-aminomutases Alanine 2,3-aminomutase sequences are disclosed, as are cells having alanine 2,3-aminomutase activity and methods of selecting for such cells. Methods for producing beta-alanine, pantothenate, 3-hydroxypropionic acid, as well as other organic compounds, are disclose... | 10/25/2011 |
| 8034603 | Nucleic acid molecule The invention relates to an isolated nucleic acid molecule encoding a polypeptide capable of producing a triterpenoid hydrocarbon. The invention also relates to the encoded polypeptide, a vector comprising the nucleic acid molecule, a recombinant non-human organism ... | 10/11/2011 |
| 8034602 | Method for producing L-arginine using Disclosed herein are a microorganism producing L-arginine and a method of producing L-arginine using the same. The microorganism is a mutant strain of the genus Corynebacterium, Corynebacterium glutamicum CJR0500. The method for L-arginine production comprise... | 10/11/2011 |
| 8034604 | High viscosity xanthan polymer preparations Increasing the molecular length of xanthan polymer makes a higher viscosity xanthan composition. Xanthan with higher specific viscosity characteristics provides more viscosity at equivalent concentration in food, industrial and oilfield applications. Methods for inc... | 10/11/2011 |
| 8030053 | Substitutional variants of hydroxynitrile lyase with high specific activity and methods of use An improved hydroxynitrile lyase characterized by having a mutation of substitution of at least one amino acid residue in the amino acid sequence of a wild-type hydroxynitrile lyase with another amino acid and by its hydroxynitrile lyase activity per transformant be... | 10/04/2011 |
| 8030052 | Midecamycin hyper producing strain A midecamycin hyper producing strain having improved productivity of midecamycin which is a member of macrolide antibiotics, and a method for producing midecamycins using the strain are provided. The midecamycin producing actinomycetes comprises a midecamycin biosyn... | 10/04/2011 |
| 7998722 | Zymomonas with improved xylose utilization Strains of Zymomonas were engineered by introducing a chimeric xylose isomerase gene that contains a mutant promoter of the Z. mobilis glyceraldehyde-3-phosphate dehydrogenase gene. The promoter directs increased expression of xylose isomerase, and whe... | 08/16/2011 |
| 7989194 | PCB-degrading recombinant bacterium, product for the bioremediation and method of bioremediation A recombinant bacterium capable to completely degrade or mineralize pollutants such as polychlorobiphenyls (PCBs), which corresponds to Cupriavidus necator strain JMS34, deposited under the access number NRRL B-30817 a product for the bioremediation of enviro... | 08/02/2011 |
| 7989193 | Compositions and methods for producing gamma-carboxylated proteins The present invention relates a host cell comprising an expression vector comprising a nucleic acid molecule encoding a protein requiring gamma-carboxylation and associated expression control sequences and a nucleic acid molecule encoding a vitamin K epoxido reducta... | 08/02/2011 |
| 7981658 | Nucleic acid molecules, vectors, and host cells encoding fluorescent protein The present invention provides a fluorescent protein having an amino acid sequence of the green fluorescent protein, the yellow fluorescent protein or mutants thereof wherein the 46th phenylalanine residue is substituted with a leucine residue. According ... | 07/19/2011 |
| 7972833 | Isolated nucleic acid molecules which encode T cell inducible factors (TIFs), the proteins encoded, and uses thereof The invention involves isolation of nucleic acid molecules, the expression of which are upregulated by interleukin-9. The amino acid sequences of the proteins which correspond to the nucleic acid molecules show some structural features of cytokines. In addition to t... | 07/05/2011 |
| 7972834 | Modified fluorescent proteins and methods for using same Embodiments of the present invention provide nucleic acid molecules encoding improved fluorescent mutants of the Katushka fluorescent protein, variants and derivatives thereof, as well as proteins and peptides encoded by these nucleic acids. Also of interest are pro... | 07/05/2011 |
| 7968325 | Methods for the biosynthesis of polyesters Coexpression of a polyhydroxyalkanoic acid synthase and a either a fatty acid:acyl-CoA transferase or an acyl-CoA synthetase in cells enables the biosynthesis of polyester materials. Plasmids, bacteria, materials, and methods for the preparation of polyesters are di... | 06/28/2011 |
| 7943361 | Mutants of and process thereof The present invention provides mutant Mycobacterium strains harboring a modified tyrosine phosphatase gene (mptpA or mptpB) wherein the mutant Mycobacterium strain is incapable of expressing the active tyrosine phosphatase. The invention provides a met... | 05/17/2011 |
| 7943363 | Methods and compositions for improving the production of products in microorganisms Methods and compositions are provided for improving the production of products, such as fuel products like ethanol, in microorganisms. In particular, methods and compositions are described for improving ethanol production utilizing genes identified in Clostridium... | 05/17/2011 |
