William F. Semple, a dentist, was awarded the first US Patent on chewing gum in 1869. His recipe contained powdered chalk.
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| Number | Title | Issue Date |
| 8227233 | Method of making foamed mycelium structure A method of making a molded part, including forming a liquid aggregate from a mixture of finely ground aggregate and a fluid. A mixture of a fungal inoculum and the liquid aggregate is formed. Nanoparticles are homogenously distributed throughout the mixture. The mi... | 07/24/2012 |
| 7795000 | Foaming composition of competitive exclusion microbes and methods of using same The present invention relates to a composition including a microbial component and a foaming component, wherein the composition can be used to prevent the proliferation, or otherwise competitively exclude the continued growth of, undesirable microbes. The present in... | 09/14/2010 |
| 7244770 | Method for evaluating an optimal dosage of defoamers in a fermentation process Methods suitable for selecting optimal defoamers for use in fermentation processes are described wherein the methods comprise: (a) determining an amount of each of two or more defoamers which provides a requisite dynamic surface tension of at most 50 mN/m at a parti... | 07/17/2007 |
| 6528305 | Method of producing infectious reovirus A simple and efficient method of producing mammalian reovirus is developed using HEK 293 cells. The method provides for fast production of reovirus in high yield. Furthermore, this method provides for a simpler purification procedure of the produced reovi... | 03/04/2003 |
| 6365149 | Porous tissue scaffoldings for the repair or regeneration of tissue The present patent describes a three-dimensional interconnected open cell porous foams that have a gradient in composition and/or microstructure through one or more directions. These foams can be made from a blend of absorbable and biocompatible polymers ... | 04/02/2002 |
| 6335191 | Automated system and method for growing bacteria An automated system and method is provided for cultivating bacteria in a fluid medium and thereafter selectively discharging the fluid medium, wherein an initial supply of the selected strain or strains of bacteria is combined with nutrients and water in ... | 01/01/2002 |
| 6146892 | Fibrillar matrices Methods and compositions are described that provide three-dimensional fibrillar matrices useful as, among other things, structural prosthetics and scaffolds for cells. The porous fibrillar matrices of the present invention have desirable mechanical proper... | 11/14/2000 |
| 6057268 | Solid form compositions for treating natural bodies of water Solid form compositions for the treatment of natural bodies of water comprising A) a quantity of beneficial aerobic microorganisms that will control at least one of an organic pollutant, an algae, and a weed in at least a portion of said body of water; an... | 05/02/2000 |
| 6022727 | Method for forming reversible colloidal gas or liquid aphrons and compositions produced A method for forming gas or liquid aphrons with reversible surfactants or emulsifiers is described. Polymers which change their emulsifying properties upon change of pH, temperature or other condition are used to form the aphrons. The aphrons are useful f... | 02/08/2000 |
| 5714379 | Biodegradation of volatile organic contaminants from air using biologically activated foam A bioreactor is disclosed which degrades volatile organic contaminants (VOCs) from air using biologically activated foam. The reactor includes a foam generator, a reaction pipe in fluid communication with the foam generator and a defoamer in fluid communi... | 02/03/1998 |
| 5690825 | Filtration method and apparatus An expansible, compressed foam is used a s a filter medium and captured particulates are released from the foam by expanding the foam to open its pores. Micro-organisms such as Cryptosporidium or Giardia cysts may be trapped and recovered at high eficienc... | 11/25/1997 |
| 5686091 | Biodegradable foams for cell transplantation A structurally rigid biodegradable foam scaffold useful for cell transplantation is provided. The foam can be loaded with nutrients and/or drugs that elute from the foam during transplant to promote growth of the cells. The foam, which features a continuo... | 11/11/1997 |
| 5616493 | Method for foam bioprocess A biological process includes the step of producing a substantially continuous foam of gas bubbles in a liquid capable of undergoing a biological process utilizing prokaryotic or eukaryotic cells. The cells are introduced into the foam after the foam is p... | 04/01/1997 |
| 5362635 | Process for the production of an amino acid using a fermentation apparatus Amino acid fermentation is conducted by fermenting bacterial cells in a culture medium in a fermentor and separating fermentation solution withdrawn from the fermentor into a solution containing said bacterial cells and a solution not containing bacterial... | 11/08/1994 |
| 5338670 | Production of bordetella pertussis toxin with a low concentration of iron A fermentation level cultivation of Bordetella pertussis bacteria on commercial scale is described. The critical factors in large scale cultivation of the bacteria are the presence of an antifoam agent and maintaining proper oxygen level and iron content ... | 08/16/1994 |
| 5288789 | Foam control in fermentation broths with a condensate of alkylphenol and aldehyde that has been polyoxyalkylated A method is disclosed for controlling foam in a fermentation broth by adding to the fermentation broth an effective amount of a composition comprising a compound corresponding to the formula: ##STR1## wherein AO is an oxyalkylene copolymer moiety of ... | 02/22/1994 |
| 5266481 | Fermentation broth degassification A post-fermentation degassing technique is provided which is directed for use in degassing foamed fermentation broths containing cultured microorganisms. Such a broth is charged while pressurized first through a heat exchanger to cool same, and then throu... | 11/30/1993 |
| 5149652 | Fermentation broth degassification A post-fermentation degassing technique is provided for use in degassing foamed fermentation broths containing cultured microorganisms. Such a broth is charged while pressurized through a nozzle to form a spray suspension in a gaseous spray chamber locate... | 09/22/1992 |
| 5024937 | Method for processing aqueous fermentation broths A method for processing aqueous fermentation broths in a bioreactor vessel, in which a foam inhibitor is added to the fermentation broth in the bioreactor vessel in order to prevent the accumulation and buildup of foam in the bioreactor vessel caused by o... | 06/18/1991 |
| 4987082 | Control of foam build up in a fermenter The use of a probe for the control of foam build up in a fermenter, which probe comprises a guard electrode (13), first and second insulators (14 and 15) separated by the guard electrode, a detecting electrode (12) separated from the guard electrode by th... | 01/22/1991 |
| 4931397 | Method for removing antifoaming agents during processing of microbial fermentations Antifoaming agents are commonly used during culturing of enzyme-producing microorganisms. These antifoams often persist through enzyme processing, slowing filtrations, clogging filtration membranes and adversely affecting the quality of the final product.... | 06/05/1990 |
| 4900553 | Method of reducing glial scar formation and promoting axon and blood vessel growth and/or regeneration through the use of activated immature astrocytes The present invention relates to "activated" immature astrocytes and methods of utilizing the activated immature astrocytes to reduce secondary necrosis and scar formation in central nervous system tissue as well as to promote axon and/or blood vessel gro... | 02/13/1990 |
| 4795708 | Novel backteria and single cell protein production therewith Single cell protein (SCP) is produced at high yields from a novel methanol assimilating Methylomonas sp. grown at elevated temperatures in an aerobic bacterial fermentation process.... | 01/03/1989 |
| 4752564 | Fermentation method and apparatus A process for the production of microbial cells by fermentation of carbonaceous material in a foam fermenter containing an oxygen-enriched nutrient medium. The process uses a source of carbon which is assimilable by the microorganism for the production of... | 06/21/1988 |
| 4654305 | Multiphase reactor systems based on foams for simultaneous growth and separation of products A nutrient gas is introduced into a liquid nutrient formulation. The resulting nutrient media is a foam. The bubble size of the gas phase is between 0.1 to 200 microns and the foam is 40-80% voids.... | 03/31/1987 |
| 4622303 | Defoamers for yeast fermentation Troublesome foaming in the fermentation of yeast is suppressed by the addition of polyglycol ethers which are derived from saturated and monounsaturated C16 -C18 fatty alcohols and which contain on an average of from 1 to 4 ethylene ... | 11/11/1986 |
| 4576915 | Strains of Rhizobium phaseoli and preparation of cyclic (1.fwdarw.2)-ଲ - Novel strains of Rhizobium phaseoli which do not produce acidic extracellular polysaccharides or their constituents, which produces cyclic ଲ-1,2-glucan effectively.... | 03/18/1986 |
| 4443549 | Production of monoclonal antibodies against bacterial adhesins Monoclonal antibodies specific for surface antigens of bacteria which act as adhesins between prokaryotic and eukaryotic cells and, in particular, K-99 pili, and methods for production thereof are described. These monoclonal antibodies may be used for the... | 04/17/1984 |
| 4340677 | Fermentation process An organism rich fluid is withdrawn from a foam fermenting apparatus by collecting and withdrawing the fluid from the foam breaker. In another embodiment the fluid from the foam breaker inside of the fermentor is subjected to a liquid/solid centrifugal ac... | 07/20/1982 |
| 4041180 | Introducing gases into fermentation liquids The bubbling of poorly soluble gases into fermentation liquids either for the replenishment of dissolved oxygen or for removal of excess super-saturated CO2 can lead to severe foaming problems, particularly in deep fermentation vessels. The pre... | 08/09/1977 |
| 3982998 | Methanol foam fermentation to single cell protein by microorganisms A process for the production of microbial cells by fermenting a carbonaceous material in a foam fermenter containing an oxygen-enriched nutrient medium. The process uses a source of carbon which is assimilable by the microorganism for the production of th... | 09/28/1976 |
| 3957585 | Method for conducting fermentation An apparatus for conducting a fermentation process for the production of single cell protein and the like. The apparatus includes a vessel with a reaction zone and has liquid atomizing means opening thereinto for the injection of atomized liquid into the ... | 05/18/1976 |