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| Number | Title | Issue Date |
| 8137946 | Recombinant GRAS strains expressing thermophilic arabinose isomerase as an active form and method of preparing food grade tagatose by using the same The present invention relates to a recombinant GRAS (Generally Recognized As Safe) strains expressing thermophilic arabinose isomerase as an active form and method of food grade tagatose by using the same, and more precisely, a gene encoding arabinose isomerase orig... | 03/20/2012 |
| 8048665 | Nucleotide sequences encoding alanine racemase from coryneform The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the alr gene, and a host-vector system having a coryneform host bacterium in which the alr gene is present in attenuated form and a vector which carries at least the... | 11/01/2011 |
| 8030051 | Alanine 2,3-aminomutases and related polynucleotides The present disclosure relates generally to polypeptides having improved alanine 2,3-aminomutase (AAM) activity, the polynucleotides encoding the AAM polypeptides, and expression vectors and host cells for expressing the AAM polypeptides. ... | 10/04/2011 |
| 8008058 | Ketose 3-epimerase, its preparation and uses An object of the present invention is to provide a novel ketose 3-epimerase, a process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, and a process for producing a ketose by using the enzyme. The present inv... | 08/30/2011 |
| 7977082 | Isomaltulose synthases, polynucleotides encoding them and uses therefor The invention is directed to novel enzymes that convert sucrose to isomaltulose. More particularly, the present invention discloses novel sucrose isomerases, polynucleotides encoding these sucrose isomerases, methods for isolating such polynucleotides and nucleic ac... | 07/12/2011 |
| 7915025 | In vivo incorporation of unnatural amino acids The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids. ... | 03/29/2011 |
| 7846707 | Nucleic acid molecules encoding alanine 2,3-aminomutases Alanine 2,3-aminomutase sequences are disclosed, as are cells having alanine 2,3-aminomutase activity and methods of selecting for such cells. Methods for producing beta-alanine, pantothenate, 3-hydroxypropionic acid, as well as other organic compounds, are disclose... | 12/07/2010 |
| 7713724 | Hydantoin racemase The invention relates to isolated polypeptides with hydantoin recemase activity, that do not suffer from substrate inhibition. Such polypeptides arc for instance isolated polypeptides with at least 87% identity with SEQ ID: NO. 2 or SEQ ED: NO. 4. The invention also... | 05/11/2010 |
| 7691619 | Sequence of thermotolerant L-rhamnose isomerase gene and use of the same The invention relates to an isolated protein including an amino acid sequence represented by SEQ ID NO:2 and having an L-rhamnose isomerase activity. This novel enzyme has a higher reaction efficiency between D-psicose and D-allose and is excellent in thermal stabil... | 04/06/2010 |
| 7666653 | Low-substrate-specific amino acid racemase and process for producing racemic amino acid The present invention provides a protein having low-substrate-specific amino acid racemase activity; DNA encoding the protein; a recombinant DNA comprising the DNA; a transformant carrying the recombinant DNA; a process for producing the protein by using the transfo... | 02/23/2010 |
| 7655451 | Alanine 2,3-aminomutase Alanine 2,3-aminomutase sequences are disclosed, as are cells having alanine 2,3-aminomutase activity and methods of selecting for such cells. Methods for producing beta-alanine, pantothenate, 3-hydroxypropionic acid, as well as other organic compounds, are disclose... | 02/02/2010 |
| 7585656 | Crystallographic structure of TcPRACA and uses therefor The present invention provides the crystal structure of the Trypanosoma cruzi PRACA proline racemase. Methods of modelling drugs that treat or prevent infection by T. cruzi are also provided, as are the drugs that are identified. ... | 09/08/2009 |
| 7439050 | genes encoding diaminopimelate epimerase Isolated nucleic acid molecules, designated MP nucleic acid molecules, which encode novel MP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MP nuc... | 10/21/2008 |
| 7399626 | Glucuronyl C5-epimerase, DNA encoding the same and uses thereof The invention is directed to a novel purified mouse C5-epimerase, fragments thereof, nucleic acids encoding the same and the recombinant production thereof. The invention is also directed to fragments of such epimerase, especially N-terminal fragments that are usefu... | 07/15/2008 |
| 7381544 | Nucleic acid that encodes a fusion protein This invention provides fusion polypeptides that include a glycosyltransferase catalytic domain and a catalytic domain from an accessory enzyme that is involved in making a substrate for a glycosyltransferase reaction. Nucleic acids that encode the fusion polypeptid... | 06/03/2008 |
| 7371555 | Polypeptides having α-H-α-amino acid amide racemase activity and nucleic acids encoding the same The invention relates to isolated polypeptides having α-H-α-amino acid amide racemase activity and nucleic acids encoding the same. The invention also relates to vectors and host cells comprising the nucleic acids according to the invention. The invention also rel... | 05/13/2008 |
| 7354745 | Method for producing L-β-lysine Purified β-amino acids are of considerable interest in the preparation of pharmacologically active compounds. Although enantiomerically pure β-amino acids, such as L-β-lysine, can be produced by standard chemical synthesis, this traditional approach is time consu... | 04/08/2008 |
| 7326781 | Polynucleotides encoding the human citron kinase polypeptide, BMSNKC0020/0021 The present invention describes a novel human protein kinase related to citron kinase, and its encoding polynucleotide. Also described are expression vectors, host cells, antisense molecules, and antibodies associated with the protein kinase polynucleotide and/or po... | 02/05/2008 |
| 7326546 | Purine-derived substance-producing bacterium and a method for producing purine-derived substance A purine-derived substance is produced by culturing a Bacillus bacterium which has an ability to produce a purine-derived substance and has enhanced activity of an enzyme of the oxidative pentosephosphate pathway. The purine-derived substance is produced in t... | 02/05/2008 |
| 7309597 | Alanine 2,3-Aminomutase Alanine 2,3-aminomutase sequences are disclosed, as are cells having alanine 2,3-aminomutase activity and methods of selecting for such cells. Methods for producing beta-alanine, pantothenate, 3-hydroxypropionic acid, as well as other organic compounds, are disclose... | 12/18/2007 |
| 7303906 | Competent bacteria The present invention discloses that a bacterium having a genome that is genetically engineered to be at least 10% smaller than the genome of its native parent strain has better transformation competence. Specific E. coli strains, having significantly reduced... | 12/04/2007 |
| 7294498 | Glycosidase enzymes A thermostable glycosidase enzymes derived from various Thermococcus, Staphylothermus and Pyrococcus organisms is disclosed. The enzymes are produced from native or recombinant host cells and can be utilized in the food processing industry, pharmaceuti... | 11/13/2007 |
| 7282359 | Plant 1-deoxy-D-xylulose 5-phosphate reductoisomerase This invention relates to an isolated nucleic acid fragment encoding a 1-deoxy-D-xylulose 5-phosphate reductoisomerase. The invention also relates to the construction of a chimeric gene encoding all or a portion of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase... | 10/16/2007 |
| 7273755 | Compositions and methods for altering biosynthesis of taxanes and taxane-related compounds Isolated nucleic acid and amino acid sequences for phenylalanine aminomutase enzyme and methods for purifying this enzyme are provided. Methods for altering biosynthesis of compounds in plant cell cultures are also provided. In particular, methods for altering produ... | 09/25/2007 |
| 7268227 | Posh nucleic acids, polypeptides and related methods The application discloses novel polypeptides and nucleic acids involved in a variety of biological processes, including viral reproduction. Related methods and compositions are also described. ... | 09/11/2007 |
| 7250282 | Isomaltulose synthases, polynucleotides encoding them and uses therefor The invention is directed to novel enzymes that convert sucrose to isomaltulose. More particularly, the present invention discloses novel sucrose isomerases, polynucleotides encoding these sucrose isomerases, methods for isolating such polynucleotides and nucleic ac... | 07/31/2007 |
| 7247456 | Preparation of fucosylated oligosaccharides This invention provides methods for practical enzymatic conversion of GDP-mannose to GDP-fucose. These methods are useful for efficient synthesis of reactants used in the synthesis of fucosylated oligosaccharides. ... | 07/24/2007 |
| 7247466 | Amino acid racemase having low substrate specificity and process for producing racemic amino acid The present invention provides a protein having low-substrate-specific amino acid racemase activity; DNA encoding the protein; a recombinant DNA comprising the DNA; a transformant carrying the recombinant DNA; a process for producing the protein by using the transfo... | 07/24/2007 |
| 7241610 | Lactic acid bacteria overproducing exopolysaccharides The invention concerns lactic acid bacteria overproducing exopolysaccharides following mutation in the gene coding for α-phosphoglucomutase. Said mutants are useful, in particular for preparing fermented products or for producing exopolysaccharides. ... | 07/10/2007 |
| 7238513 | Nucleic acid sequences encoding protein disulfide isomerase Protein disulfide isomerase is a major component of Conus venom ducts. The invention relates to a protein disulfide isomerase (PDI) from Conus snails, a nucleic acid sequence encoding the Conus protein disulfide isomerase, and to methods for fol... | 07/03/2007 |
| 7229797 | Enzymatic synthesis of deoxyribonucleosides The present invention relates to a method for the in vitro enzymatic synthesis of deoxyribonucleosides and enzymes suitable for this method. ... | 06/12/2007 |
| 7208307 | Preparation of acariogenic sugar substitutes The invention relates to sucrose isomerases, to DNA sequences that code for sucrose isomerases, and to novel processes for the production of non-cariogenic sugars. ... | 04/24/2007 |
| 7205141 | Gene sequence of L-rhamnose isomerase having new catalytic function and use thereof In the rare sugar strategy of Izumoring (FIG. 1), it is intended to establish a reaction system of producing rare sugars of many types by acquiring an isomerase which acts on various rare aldoses and, therefore, is most efficient in producing variou... | 04/17/2007 |
| 7198932 | Gdp-4-keto-6-deoxy-d-mannose-3,5-epimerase-4-reductase gene derived from arabidopsis thaliana The present invention relates to a gene for an enzyme involving in the synthesis of GDP-L-fucose. Particularly, the present invention relates to a GDP-4-keto-6-deoxy-D-mannose-3, 5-epimerase-4-reductase gene derived from Arabidopsis thaliana, and a process fo... | 04/03/2007 |
| 7198933 | xylose isomerase polypeptides and nucleic acids encoding same The present invention provides novel isolated polynucleotides encoding a novel xylose isomerases capable of catalyzing the conversion of glucose to fructose and nucleic acids encoding for such isomerase. The present invention also provides a method of producing the ... | 04/03/2007 |
| 7192748 | Isolated polynucleotides encoding phosphohexuloisomerase from The present invention provides polypeptides and polynucleotides involved in C1 assimilation in Methylophilus methylotrophus and methods of producing amino acids in microorganisms having enhanced or attenuated expression of these polypeptides and/or polynucleo... | 03/20/2007 |
| 7192758 | Polynucleotides encoding phosphoribosylanthranilate isomerase This invention relates to isolated nucleic acid fragments encoding phosphoribosylanthranilate isomerases, a tryptophan biosynthetic enzyme. The invention also relates to the construction of a chimeric gene comprising the nucleic acid fragment, in sense or antisense ... | 03/20/2007 |
| 7157082 | Cardioprotective therapies based on enzymatic elimination of lipid peroxides by allene oxide synthase The present invention relates to methods and compositions related to the use of enzymes of the allene oxide synthase family for reducing myocardial ischemia reperfusion injury associated with myocardial infarction, thrombolysis, angioplasty and coronary bypass surge... | 01/02/2007 |
| 7148192 | Neuroprotective dietary supplement The invention relates to a novel dietary supplement mixture having improved neuroprotective activity and preventing, ameliorating or counteracting neurodegeneration and preventing, counteracting and/or improving cognitive function decline. It also provides a dietary... | 12/12/2006 |
| 7135283 | Topoisomerase type II gene polymorphisms and their use in identifying drug resistance and pathogenic strains of microorganisms Novel polymorphisms of prokaryotic topoisomerase type II Gyr A, Gyr B and parC gene loci are provided. These polymorphisms differentiate very closely related organisms and provide a means to identify pathogenicity and drug resistance. For example, drug resistance su... | 11/14/2006 |
