Did You Know...
...that after Parker Brothers executives turned down the game of Monopoly because it had "52 fundamental errors" (including taking too long to play), a copy of the game wound up in the home of the company president who stayed up until 1 a.m. to finish playing it? He was so impressed by the game that the next day he wrote to inventor Charles Darrow and offered to buy it!
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| Number | Title | Issue Date |
| 8187832 | Method of detecting an amount of a cholinesterase inhibitor in a sample A method of detecting an amount of a cholinesterase inhibitor in a sample comprising steps of: (a) contacting the sample with an agent capable of recovering the cholinesterase inhibitor from the sample so that the cholinesterase inhibitor is recovered, wherein the a... | 05/29/2012 |
| 7494783 | Method for assessing trait anxiety by determining cholinergic status The invention provides methods/kits for assessing levels of trait or state anxiety in a subject by comparing genotypes and/or expression patterns at the ACHE, PON1 and/or BChE genes to the genotype and/or expression pattern of the genes in a reference population who... | 02/24/2009 |
| 7422892 | Enzyme-based device for environmental monitoring A sensor for the intermittent or continuous detection of the presence of at least one analyte in an environmental sample includes at least one enzyme that is selected to either (i) catalyze a reaction of the analyte to chemically convert the analyte to a product com... | 09/09/2008 |
| 7371564 | Apparatus for automatically analyzing genetic and protein materials using photodiodes An apparatus for automatically analyzing genetic and protein materials using photodiodes. The apparatus comprises a computer for controlling the entire operation of the apparatus and analyzing a voltage level from a characteristic detector to analyze states of the g... | 05/13/2008 |
| 7319029 | Lipase from sp. strain T1 A biologically pure culture of Geobacillus Strain T1 bacteria isolated from Palm Oil Mill Effluent capable of producing thermostable lipase T1 gene. The production of thermostable lipase T1 gene from a novel Geobacillus bacterium having a designated as... | 01/15/2008 |
| 7252962 | Method for detecting sensitivity to acetylcholine esterase in insects A method for checking for sensitivity of acetylcholine esterase in insects using a single insect, includes homogenizing a single insect in aqueous, neutral to acid pH phosphate buffer, providing a solution of acetylcholine iodide in neutral to acid pH phosphate buff... | 08/07/2007 |
| 7238483 | Method for detecting catalytic activity This invention has as its object a method for detecting catalytic activity of a sample, characterized in that it comprises: the incubation of a substrate (S) with the sample that may have the catalytic activity that it is desired to detect, the addition of a reagent... | 07/03/2007 |
| 7217507 | Method for detecting ligands and targets in a mixture The invention provides a method of characterizing a target that binds to a ligand. The method comprises providing ligands, optionally attached to a support, and contacting the ligands with targets to allow at least one target to bind to at least one ligand. The meth... | 05/15/2007 |
| 7141385 | Microcantilever apparatus and methods for detection of enzymes, enzyme substrates, and enzyme effectors An apparatus and a method are provided for detecting an enzyme, or or for detecting a substrate of an enzyme or for detecting an enzyme effector such as an inhibitor, by measuring a change in deflection of a microcantilever having a substrate or an enzyme, respectiv... | 11/28/2006 |
| 7026111 | Methods and reagents for improved cell-based assays The ability to efficiently determine the state of enzyme expression in cells has long been desired as material to the diagnosis of disease. This invention relates to cytoenzymology, and more particularly to improved reagents for use in cell-based assays, especially ... | 04/11/2006 |
| 6996473 | Method for screening and producing compound libraries A secondary compound library produced by a method of screening a compound library or portion thereof by absorption is provided. The method includes a step (i) that screens a primary compound library or portion thereof having a plurality of test samples containing is... | 02/07/2006 |
| 6968063 | Dynamic volume adjustment in a slot machine A casino gaming machine includes a speaker structured to produce a game audio output having a volume, an ambient noise level (ambient noise level) detector structured to detect an ambient noise level proximate the gaming machine, and an dynamic volume controller con... | 11/22/2005 |
| 6815185 | Methods of creating constructs useful for introducing sequences into embryonic stem cells This invention provides novel nucleotide constructs. Also provided are methods for making DNA constructs useful for introducing sequences into and disrupting the function of a gene in a cell, particularly an embryonic stem cell. ... | 11/09/2004 |
| 6764831 | Methods and compositions for pain management The present invention provides novel methods and diagnostic kits for the objective measurement of the severity of pain or stress being experienced by a patient with a disorder, diagnosis and treatment for patients suffering from painful disorders, and monitoring the... | 07/20/2004 |
| 6746850 | Assay for detecting, measuring and monitoring the activities and concentrations of proteins and methods of use thereof An assay for detecting, measuring, or monitoring the activity or concentration of at least two proteins that have similar or overlapping properties is disclosed. The assay comprises first determining the sensitivity coefficients of the substrates for each of the pro... | 06/08/2004 |
| 6673565 | Enzymatic polymeric sensors A sensor for detecting an analyte enzyme includes at least one substrate compound and at least one indicator compound selected to produce a measurable change of state as a result of the interaction of the substrate and at least one target or analyte enzym... | 01/06/2004 |
| 6660491 | Process for producing dietary sterol fatty acid esters A process for enzymatically producing, from a vegetable oil deodorizer distillate, a dietary sterol fatty acid ester superior in flavor qualities (e.g., color, odor and taste) and safety and containing no or little trans fatty acids, wherein the condition... | 12/09/2003 |
| 6605440 | Method for determining analyte level A multilayer analytical element for determining a level of an analyte on a substrate and adapted for use with hydrogen peroxide and an affinity-enzymatic compound of formula A-C-B, wherein A is a detecting agent having affinity for the analyte, B is an en... | 08/12/2003 |
| 6551631 | Antimicrobial agents isolated from Aloe vera Antimicrobial agents and method for isolation thereof from the gel liquid of Aloe vera includes at least one antimicrobial agent isolated from the clear gel isolated from the whole leaf of the Aloe vera plant, wherein the antimicrobial agent is an agent p... | 04/22/2003 |
| 6461831 | Diagnostic test for alzheimer's disease A method for the diagnosis of Alzheimer's disease (AD) in a patient, comprising the steps of: (1) providing a sample of an appropriate body fluid from said patient; (2) detecting the presence of acetylcholinesterase (AChE) with an altered glycosylation pa... | 10/08/2002 |
| 6406876 | Immobilized enzymes biosensors for chemical toxins Methods, compositions and materials useful in the detection of organophosphorous and organosulfur compounds are disclosed. In particular, biosensors wherein a porous or a non-porous support having an enzyme immobilized upon or within are disclosed. The bi... | 06/18/2002 |
| 6403329 | Methods of detecting methylphosphonic compounds Methods and apparatus are disclosed for screening chemical samples to detect the presence of chemical warfare agents, chemical warfare agent precursors and degradation products formed therefrom. Particular applications include detection of the presence of... | 06/11/2002 |
| 6326139 | Method of screening for genetic predisposition to anticholinesterase therapy A method of screening for a genetic predisposition to anticholinesterase exposure. The method includes the steps of obtaining a peripheral blood sample, and then analysing serum from the blood sample for BuChE levels and inhibitor-susceptibilities. The DN... | 12/04/2001 |
| 6291200 | Enzyme-containing polymeric sensors A sensor for detecting the presence of at least one analyte includes at least one enzyme that is selected to either (i) catalyze a reaction of the analyte to chemically convert the analyte to a product compound or (ii) be inhibited by the analyte in the p... | 09/18/2001 |
| 6114134 | Method for assaying biological specimens for substances contained in the components thereof and reagent to be used in this method A method for assaying biological specimens for substances contained in the components of each specimen by the use of one or more kinds of calixarenes; and a reagent comprising one or more kinds of calixarenes. The method utilizes complexes formed by calix... | 09/05/2000 |
| 6083539 | Buckwheat starch syrup, method for preparing the same, and foods containing the same The present invention relates to a buckwheat starch syrup prepared by liquefying, saccharisfying, and proteolyzing starch from buckwheat flour, a method for preparing the buckwheat starch syrup, and various foods containing the same. The buckwheat starch ... | 07/04/2000 |
| 6051389 | Enzyme sensor The present invention relates to an enzyme sensor for measuring the concentration or activity of an analyte in a test fluid. The sensor has at least one enzyme layer comprising an immobilized enzyme for which the analyte is a substrate. The immobilized en... | 04/18/2000 |
| 5989825 | Excitatory amino acid transporter gene and uses This invention relates to novel mammalian excitatory amino acid transporter proteins and genes encoding such proteins. The invention is directed towards the isolation, characterization and use of human excitatory amino acid transporter proteins for pharma... | 11/23/1999 |
| 5807696 | Method for determination of cholesterol in low-density lipoprotein The present invention relates to a method for the determination of cholesterol in low-density lipoprotein (LDL) in a sample containing LDL, which comprises eliminating cholesterol in high-density lipoprotein in the sample, subjecting the sample to a react... | 09/15/1998 |
| 5736352 | Method and apparatus for determination of the activity of cholesterol oxidase and method and apparatus for evaluation of the toxicity of chemical substances A method for determination of activity of a cholesterol oxidase comprises the following steps. A monomolecule film comprising a sterol and a phospholipid is formed on a surface of a cholesterol oxidase solution. Subsequently, a surface pressure of the mon... | 04/07/1998 |
| 5707820 | Reagent and assay methods including a phenazine-containing indicator A new reagent and methods for measuring the concentration of (or detecting the presence of) an analyte in a sample. The reagent includes a phenazine-containing compound and an enzyme. The phenazine-containing compound must be of sufficient type to form a ... | 01/13/1998 |
| 5654152 | Method of measuring enzyme activity by using a column having an immobilized substrate Enzyme activity is measured promptly with a high accuracy by introducing an enzyme, the activity of which is to be measured, into a column comprising a hollow tube packed with a filler comprising a support and a substrate that can be recognized by the enz... | 08/05/1997 |
| 5624831 | Immobilized acetylcholinesterase stabilized by a film of gelatin or albumin containing trehalose Acetylcholinesterase and/or a receptor of acetylcholinesterase is immobilized on a solid support and stabilized by covering with a protective film of gelatin and/or albumin containing trehalose. The film is applied by covering the immobilized acetylcholin... | 04/29/1997 |
| 5605795 | Assays using chemiluminescent, enzymatically cleavable substituted 1,2-dioxetanes and kits therefor Dioxetane compounds reactable with an enzyme to release optically detectable eneregy are disclosed. These compounds have the formula: ##STR1## wherein T is a cycloalkyl group or a fused polycyclo-alkylidene group bonded to the dioxetane ring through ... | 02/25/1997 |
| 5595883 | Method of diagnosing alzheimer's disease by measuring acetylcholinesterase activity in ocular fluid A method is provided for diagnosing of senile dementia of the Alzheimer type (Alzheimer's disease) by measuring acetylcholinesterase (AChE) activity in ocular fluids and determining if such AChE activity is elevated over that found in ocular fluids of pat... | 01/21/1997 |
| 5587295 | Method for producing affino-enzymatic compounds and visualizing agent and application thereof The invention is a non-invasive diagnostic test which is performed on the surface of the skin. This test indicates skin cholesterol levels which can provide information about the extent of aortic atherosclerosis. The invention also relates to reagents in ... | 12/24/1996 |
| 5543299 | Extender containing polymer compositions and uses thereof The invention relates to polymeric compositions useful in analyte determination. The compositions contain a polymer, a reagent system for analyte determination, and an extender. The last component alleviates tackiness in the composition, and thus reduces ... | 08/06/1996 |
| 5543295 | Chemiluminescent 3--(Substituted adamant--2'--Ylidene) 1,2--Dioxetanes Enzymatically clearable chemiluminescent 1,2-dioxetane compounds capable of producing light energy when decomposed, substantially stable at room temperature before a bond by which an enzymatically clearable labile substituent thereof is intentionally clea... | 08/06/1996 |
| 5527509 | Colorimetric enzymic analysis A colorimetric enzymic analytical test element comprises a support and a plurality of reaction zones incorporating a dried enzyme composition, dyestuff and reagent adapted to provide a substantial dosage independent colorimetric display when the concentra... | 06/18/1996 |
| 5506097 | Method for inhibiting ଲ-protein enzymatic activity A method of inhibiting the function of ଲ-protein, particularly enzymatic activity, such as esterase (cholinesterase) or proteinase activity, is to contact ଲ-protein with a compound which inhibits such enzymatic activity. Examples of such inhib... | 04/09/1996 |
