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...Daniel Webster invented a "bull plow" to pull out tree stumps. It didn't catch on because it was huge and required four oxen to pull it!
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| Number | Title | Issue Date |
| 8187854 | Lipase variants The invention provides variant lipases, preferably, variants with reduced tendency to odor generation obtained by introducing mutations in one or more regions identified in a parent lipase. ... | 05/29/2012 |
| 8012732 | Fungal lypolytic and amylase enzyme composition and methods using the same A fungal wild-type lipolytic enzyme having a higher ratio of activity on polar lipids compared with triglycerides, wherein the enzyme preferably has a phospholipid:triglyceride activity ratio of at least 4. Preferably, the lipolytic enzyme according to the present i... | 09/06/2011 |
| 7977080 | Phospholipases, nucleic acids encoding them and methods for making and using them The invention provides novel polypeptides having phospholipase activity, including, e.g., phospholipase A, B, C and D activity, patatin activity, phosphatidic acid phosphatases (PAP)) and/or lipid acyl hydrolase (LAH) activity, nucleic acids encoding them and antibo... | 07/12/2011 |
| 7943360 | Phospholipases, nucleic acids encoding them and methods for making and using them The invention provides novel polypeptides having phospholipase activity, including, e.g., phospholipase A, B, C and D activity, patatin activity, lipid acyl hydrolase (LAH) activity, nucleic acids encoding them and antibodies that bind to them. Industrial methods, e... | 05/17/2011 |
| 7927855 | Esters of long-chain alcohols and preparation thereof Disclosed are esters and a process for the preparation of the esters represented by formula 1: The process includes reacting an alcohol with a long-chain acid R2COOH or long-chain ester R2COOR4 | 04/19/2011 |
| 7919298 | Polypeptides having lipase activity and polynucleotides encoding same The invention provides polypeptides obtained by introducing mutations in one or more regions identified in a parent lipase. The polypeptides of the present invention have surprisingly been found to have a low specific activity towards short chain fatty acids leading... | 04/05/2011 |
| 7811802 | Lipase powder composition and a process for preparing an esterified compound by using the same There is provided a lipase composition comprising (a) a powdered lipase which is a lipase derived from Rhizomucor sp. or a powdered lipase which is a lipase derived from Penicillium sp. and (b) a powdered lipase selected from the group consisting of a ... | 10/12/2010 |
| 7790429 | Robust multi-enzyme preparation for the synthesis of fatty acid alkyl esters A process for the preparation of short-chain alkyl esters of fatty acids, preferably fatty acid methyl esters (biodiesel) in solvent-free system is disclosed. In particular, the process comprises (a) providing a fatty acid source, (b) stepwise adding a short-chain f... | 09/07/2010 |
| 7781200 | Polypeptides having lipase activity and polynucleotides encoding same The present invention relates to a new wild-type lipase, its nucleic acid sequences and the amino acid sequences thereof. This new lipase shows washing performance in the form of wild-type. The present invention also relates to the method for producing the lipase an... | 08/24/2010 |
| 7754462 | Enzyme catalysis in the presence of ionic liquids The invention relates to the implementation of enzyme-catalysed reactions in the presence of ionic liquids. ... | 07/13/2010 |
| 7632669 | Lipolytic enzyme variants The substrate specificity of a lipolytic enzyme can be modified by making alterations to the amino acid sequence in a defined region of the lipolytic enzyme, so as to increase the level of a desired activity or to decrease the level of an undesired activity. Thus, t... | 12/15/2009 |
| 7622290 | Fungal lipolytic enzymes, nucleic acids encoding, and uses thereof A fungal wild-type lipolytic enzyme having a higher ratio of activity on polar lipids compared with triglycerides, wherein the enzyme preferably has a phospholipid:triglyceride activity ratio of at least 4. Preferably, the lipolytic enzyme according to the present i... | 11/24/2009 |
| 7611880 | Enzymatic ammonolysis process for the preparation of intermediates for DPP IV inhibitors An enzymatic ammonolysis process is provided for the preparation of intermediates used in preparing dipeptidyl peptidase IV inhibitors wherein the enzyme Candida antarctica lipase-B is used to catalyze the ammonolysis process. ... | 11/03/2009 |
| 7550280 | Lipases and uses thereof The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel lipolytic enzyme from Aspergillus niger. The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the ... | 06/23/2009 |
| 7485445 | Plant gene and uses thereof A novel gene isolated from Deschampsia antarctica coding for a lipase like protein is disclosed. A system for production of recombinant enzyme is also disclosed as well as uses for the enzyme. ... | 02/03/2009 |
| 7473541 | Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase Afamily members possessing triacylglycerol lipase and acylglycerol transacylase activities Isolated novel and purified and characterized phospholipase A2, referred to herein as calcium-independent phospholipase A2zeta (iPLA2zeta) having SEQ. ID. NO: 2 (See FIG. 1), and nucleic acid sequence (SEQ. ID. NO: 4), and cal... | 01/06/2009 |
| 7468266 | Isolated genomic polynucleotide fragments that encode human lipoprotein-associated phospholipase A2 The invention is directed to isolated genomic polynucleotide fragments that encode human lipoprotein-associated phospholipase A2, vectors and hosts containing the fragment and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these ... | 12/23/2008 |
| 7416869 | Enzyme delivery systems, application in water based products Aqueous enzyme delivery systems as well as aqueous cosmetics and personal care products were provided which comprise at least one stabile enzyme and a polyglycerol containing at least 15 carbons. In addition, stabile non-aqueous enzyme delivery systems which are dis... | 08/26/2008 |
| 7416867 | Enzymatic production of (meth)acrylic acid esters A method for the production of partially esterified (meth)acrylic acid esters of polyalcohols and the use thereof. ... | 08/26/2008 |
| 7416853 | Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds. ... | 08/26/2008 |
| 7407779 | Modification of solid 3-sn-phosphoglycerides Methods for hydrolyzing solid ungranulated lysophosphatidylcholine with phospholipase A2 are provided. Also disclosed are methods for making a lipid matrix of lysophosphatidylcholine, monoglyceride and fatty acid, and lipid matrices of particular structur... | 08/05/2008 |
| 7407786 | Lipase genes New lipase enzymes (both nucleic acids and polypeptides) are provided. Compositions which include these polypeptides, proteins, nucleic acids, recombinant cells, as well as methods involving the enzymes, antibodies to the enzymes, and methods of using the enzymes ar... | 08/05/2008 |
| 7402414 | Enzymatic process for deacetylation of a phenoxy-alkynyl acetate to the corresponding alcohol A process for preparing the compound of formula II by reacting the compound of formula I with an enzyme that can hydrolyze the ester bond: where * indicates a chiral center, R1 and R... | 07/22/2008 |
| 7396667 | Enzymatic depolymerization process of polylactic acid, and producing process of polylactic acid using depolymerization product A depolymerizing process of polylactic acid, wherein the polylactic acid is depolymerized in the presence of a hydrolase in an organic solvent or a supercritical fluid, thereby producing a re-polymerizable oligomer. A producing process of polylactic acid, wherein th... | 07/08/2008 |
| 7396657 | Lipase variants Attaching a peptide extension to the C-terminal amino acid of a lipase reduces the tendency to form odor. This may lead to lipase variants with a reduced odor generation when washing textile soiled with fat which includes relatively short-chain fatty acyl groups (e.... | 07/08/2008 |
| 7384787 | Increasing perhydrolase activity in esterases and/or lipases The invention provides for methods of modifying n esterase or a lipase enzyme to introduce perhydrolase activity or to increase the already-existing perhydrolase activity. The invention also provides for methods of converting an polypeptide having predominantly este... | 06/10/2008 |
| 7361741 | Antibody, or fragment thereof, capable of binding specifically to human pancreatic lipase An antibody, or fragment thereof, capable of binding specifically to one or more human dietary enzymes, said antibody or fragment thereof comprising a heavy chain variable domain derived from an immunoglobulin naturally devoid of light chains, or a functional equiva... | 04/22/2008 |
| 7355004 | Protein lipase inhibitor for flour and dough The present invention relates to the isolation of and characterization of a novel lipase inhibitor and its effect on different lipases. The present invention also relates to the use of a lipase inhibitor as a screen for lipases. The present invention also relates to... | 04/08/2008 |
| 7341857 | Production of beta-hydroxypalmitate methyl esterase from sp.0-0013 (FERM BP-08660) The present invention provides a novel esterase derived from Ideonella sp. 0-0013 strain (FERM BP-08660) having the following properties: (1) function, substrate specificity: hydrolyzes methyl 3-hydroxypalmitate to generate 3-hydroxypalmitic acid and methanol... | 03/11/2008 |
| 7332318 | Calcium-independent phospholipases A, genes thereof and promoter of the same Novel calcium-independent phospholipases A2; genes encoding the same; an antibody against them; an inherent promoter or a regulator gene which comprises a base sequence occurring in intron and inducing site-specific expression in response to an external s... | 02/19/2008 |
| 7319015 | Methods and compositions for using alveolar macrophage phospholipase A2 The present invention is directed to methods and compositions for improving pulmonary surfactant catabolism. More specifically, the specification describes methods and compositions for making and using a lysosomal phospholipase A2 in methods for the diagnosis, and t... | 01/15/2008 |
| 7319029 | Lipase from sp. strain T1 A biologically pure culture of Geobacillus Strain T1 bacteria isolated from Palm Oil Mill Effluent capable of producing thermostable lipase T1 gene. The production of thermostable lipase T1 gene from a novel Geobacillus bacterium having a designated as... | 01/15/2008 |
| 7314742 | Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds which inhibit the enzym... | 01/01/2008 |
| 7314739 | Lipase variants The invention relates to a lipase variant which can be prepared by carrying out, on the amino acid sequence of a starting lipase selected from the lipase homologous family I.1 or I.2, at least one amino acid substitution in those positions which correspond to the po... | 01/01/2008 |
| 7312062 | Lipolytic enzyme variants The substrate specificity of a lipolytic enzyme can be modified by making alterations to the amino acid sequence in a defined region of the lipolytic enzyme, so as to increase the level of a desired activity or to decrease the level of an undesired activity. Thus, t... | 12/25/2007 |
| 7303904 | Stable gene variants of lipases The present invention relates to the generation and production of novel thermostable, organic solvent stable and pH tolerant lipase gene variants. The invention also relates to methods of selecting lipase variants for high temperatures and for their purification. | 12/04/2007 |
| 7294496 | Cloned human lysophospholipase A cloned of a human brain lysophospholipid-specific lysophospholipase enzyme molecule, its potential use for treatment of a host of diseases and method of inactivation are disclosed. Also disclosed are its distribution in tissue sand detailed kinetic analysis. hLyso... | 11/13/2007 |
| 7288400 | Nucleic acids encoding esterases and methods of making and using them The invention relates to esterases and to polynucleotides encoding the esterases. In addition methods of designing new esterase method of use thereof are also provided. The esterases have increased activity and stability at increased pH and temperature. ... | 10/30/2007 |
| 7282233 | Chemically modified lipolytic enzyme Lipolytic enzymes are chemically modified by covalently linking one or more (particularly 1-3) hydrophobic groups to the enzyme molecule. The chemical modification improves the performance of the lipolytic enzyme, e.g., in baking or in detergents. ... | 10/16/2007 |
| 7271139 | Lipolytic enzyme genes The inventors have isolated novel lipolytic enzyme genes with a high homology to the T. lanuginosus lipase gene and thus well suited for use in gene shuffling. Accordingly, the invention provides a method of generating genetic diversity into lipolytic enzymes... | 09/18/2007 |
